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DE69132091D1 - Verfahren zur Herstellung von Indolderivaten - Google Patents

Verfahren zur Herstellung von Indolderivaten

Info

Publication number
DE69132091D1
DE69132091D1 DE69132091T DE69132091T DE69132091D1 DE 69132091 D1 DE69132091 D1 DE 69132091D1 DE 69132091 T DE69132091 T DE 69132091T DE 69132091 T DE69132091 T DE 69132091T DE 69132091 D1 DE69132091 D1 DE 69132091D1
Authority
DE
Germany
Prior art keywords
preparation
indole derivatives
acid
indole
methylbenzenemethanesulphonamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69132091T
Other languages
English (en)
Other versions
DE69132091T2 (de
Inventor
Frederick David Albinson
Derek Leslie Crookes
John Wilson Macfarla Mackinnon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE69132091D1 publication Critical patent/DE69132091D1/de
Application granted granted Critical
Publication of DE69132091T2 publication Critical patent/DE69132091T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Glass Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69132091T 1990-06-21 1991-06-20 Verfahren zur Herstellung von Indolderivaten Expired - Fee Related DE69132091T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909013845A GB9013845D0 (en) 1990-06-21 1990-06-21 Process

Publications (2)

Publication Number Publication Date
DE69132091D1 true DE69132091D1 (de) 2000-05-11
DE69132091T2 DE69132091T2 (de) 2000-10-12

Family

ID=10677976

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132091T Expired - Fee Related DE69132091T2 (de) 1990-06-21 1991-06-20 Verfahren zur Herstellung von Indolderivaten

Country Status (8)

Country Link
US (1) US5103020A (de)
EP (1) EP0462837B1 (de)
JP (1) JP3166125B2 (de)
AT (1) ATE191476T1 (de)
DE (1) DE69132091T2 (de)
DK (1) DK0462837T3 (de)
ES (1) ES2144995T3 (de)
GB (1) GB9013845D0 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133453A (en) * 1998-05-15 2000-10-17 Pharm-Eco Laboratories, Inc. Method for making substituted indoles
JP4897221B2 (ja) 2002-12-20 2012-03-14 チバ ホールディング インコーポレーテッド アミン類の合成及びその合成のための中間体
EA013123B1 (ru) 2005-04-13 2010-02-26 Ньюрэксон, Инк. Замещенные индолы, обладающие активностью ингибирования nos
TW200808780A (en) * 2006-04-13 2008-02-16 Neuraxon Inc 1,5 and 3,6- substituted indole compounds having NOS inhibitory activity
CN100554252C (zh) * 2007-07-17 2009-10-28 浙江苏泊尔制药有限公司 一种琥珀酸舒马曲坦的制备方法
US20090131503A1 (en) * 2007-11-16 2009-05-21 Annedi Subhash C 3,5 - substituted indole compounds having nos and norepinephrine reuptake inhibitory activity
WO2009062319A1 (en) * 2007-11-16 2009-05-22 Neuraxon, Inc. Indole compounds and methods for treating visceral pain
US20090163451A1 (en) * 2007-11-16 2009-06-25 Frank Porreca Methods for treating visceral pain
CN102432519B (zh) * 2011-11-21 2013-12-11 山东新华制药股份有限公司 3-(2-氨乙基)-n-甲基-1h-吲哚-5-甲烷磺酰胺的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55105664A (en) * 1979-02-08 1980-08-13 Kawaken Fine Chem Co Ltd Preparation of tryptamine
IT1170387B (it) * 1982-06-07 1987-06-03 Glaxo Group Ltd Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds

Also Published As

Publication number Publication date
ATE191476T1 (de) 2000-04-15
DK0462837T3 (da) 2000-09-11
JP3166125B2 (ja) 2001-05-14
EP0462837B1 (de) 2000-04-05
JPH04230258A (ja) 1992-08-19
US5103020A (en) 1992-04-07
ES2144995T3 (es) 2000-07-01
GB9013845D0 (en) 1990-08-15
DE69132091T2 (de) 2000-10-12
EP0462837A2 (de) 1991-12-27
EP0462837A3 (en) 1992-09-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee