DE69117588D1 - Zusammensetzung und Verfahren zur Bestimmung von Ketonkörpern - Google Patents
Zusammensetzung und Verfahren zur Bestimmung von KetonkörpernInfo
- Publication number
- DE69117588D1 DE69117588D1 DE69117588T DE69117588T DE69117588D1 DE 69117588 D1 DE69117588 D1 DE 69117588D1 DE 69117588 T DE69117588 T DE 69117588T DE 69117588 T DE69117588 T DE 69117588T DE 69117588 D1 DE69117588 D1 DE 69117588D1
- Authority
- DE
- Germany
- Prior art keywords
- composition
- beta
- hydroxybutyrate
- ketone bodies
- reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 150000002576 ketones Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- WHBMMWSBFZVSSR-GSVOUGTGSA-M (R)-3-hydroxybutyrate Chemical compound C[C@@H](O)CC([O-])=O WHBMMWSBFZVSSR-GSVOUGTGSA-M 0.000 abstract 4
- KIUMMUBSPKGMOY-UHFFFAOYSA-N 3,3'-Dithiobis(6-nitrobenzoic acid) Chemical compound C1=C([N+]([O-])=O)C(C(=O)O)=CC(SSC=2C=C(C(=CC=2)[N+]([O-])=O)C(O)=O)=C1 KIUMMUBSPKGMOY-UHFFFAOYSA-N 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 102000034279 3-hydroxybutyrate dehydrogenases Human genes 0.000 abstract 1
- 108090000124 3-hydroxybutyrate dehydrogenases Proteins 0.000 abstract 1
- 102000028526 Dihydrolipoamide Dehydrogenase Human genes 0.000 abstract 1
- 108010028127 Dihydrolipoamide Dehydrogenase Proteins 0.000 abstract 1
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- FCCDDURTIIUXBY-UHFFFAOYSA-N lipoamide Chemical compound NC(=O)CCCCC1CCSS1 FCCDDURTIIUXBY-UHFFFAOYSA-N 0.000 abstract 1
- 229950006238 nadide Drugs 0.000 abstract 1
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 150000003573 thiols Chemical class 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/904—Oxidation - reduction indicators
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/20—Oxygen containing
- Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/545,634 US5190863A (en) | 1990-06-29 | 1990-06-29 | Composition for determining the presence or concentration of D-β-hydroxybutyrate |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69117588D1 true DE69117588D1 (de) | 1996-04-11 |
DE69117588T2 DE69117588T2 (de) | 1996-10-10 |
Family
ID=24176972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69117588T Expired - Fee Related DE69117588T2 (de) | 1990-06-29 | 1991-06-15 | Zusammensetzung und Verfahren zur Bestimmung von Ketonkörpern |
Country Status (9)
Country | Link |
---|---|
US (2) | US5190863A (de) |
EP (1) | EP0463524B1 (de) |
JP (1) | JP3118029B2 (de) |
AT (1) | ATE135052T1 (de) |
AU (1) | AU628751B2 (de) |
CA (1) | CA2042645A1 (de) |
DE (1) | DE69117588T2 (de) |
DK (1) | DK0463524T3 (de) |
ES (1) | ES2084061T3 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5190863A (en) * | 1990-06-29 | 1993-03-02 | Miles Inc. | Composition for determining the presence or concentration of D-β-hydroxybutyrate |
DE69129308T2 (de) * | 1991-12-12 | 1999-01-07 | Asahi Kasei Kogyo K.K., Osaka | Hochempfindliche bestimmung von d-3-hydroxybutiersäure oder acetessigsäure und zusammensetzung dafür |
US5510245A (en) * | 1992-09-08 | 1996-04-23 | Bayer Corporation | Composition and method of assaying for ketone bodies |
US5516700A (en) * | 1993-05-28 | 1996-05-14 | Chimera Research And Chemical, Inc. | Automated urinalysis method |
US6541216B1 (en) | 1999-12-22 | 2003-04-01 | Roche Diagnostics Corporation | Amperometric biosensor test strip |
US6583722B2 (en) | 2000-12-12 | 2003-06-24 | Kimberly-Clark Worldwide, Inc. | Wetness signaling device |
US6603403B2 (en) | 2000-12-12 | 2003-08-05 | Kimberly-Clark Worldwide, Inc. | Remote, wetness signaling system |
US6762035B1 (en) * | 2002-02-04 | 2004-07-13 | Surendra K. Gupta | Method and test strips for the measurement of fat loss during weight loss programs |
US6703216B2 (en) | 2002-03-14 | 2004-03-09 | The Regents Of The University Of California | Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB) |
US7723118B2 (en) * | 2002-10-18 | 2010-05-25 | Alt Bioscience, Llc. | Compositions and methods for simultaneous detection of volatile sulfur compounds and polyamines |
AU2006326040B2 (en) * | 2005-12-15 | 2012-02-09 | Société des Produits Nestlé S.A. | Compositions and methods for preserving brain function |
EP3391812B1 (de) | 2007-01-23 | 2025-01-01 | Ascensia Diabetes Care Holdings AG | Vorrichtung zum testen von analyten |
US7910778B2 (en) * | 2007-08-25 | 2011-03-22 | Exxonmobil Chemical Patents Inc. | Process for producing cyclohexylbenzene |
KR101175849B1 (ko) * | 2007-09-21 | 2012-08-24 | 엑손모빌 케미칼 패턴츠 인코포레이티드 | 사이클로헥실벤젠의 제조방법 |
JP5192546B2 (ja) * | 2007-09-21 | 2013-05-08 | エクソンモービル ケミカル パテンツ インコーポレイテッド | シクロヘキシルベンゼンの製造プロセス |
US8084648B2 (en) * | 2008-02-12 | 2011-12-27 | Exxonmobil Chemical Patents Inc. | Process for producing cyclohexylbenzene |
CN101998942B (zh) | 2008-04-14 | 2016-02-03 | 埃克森美孚化学专利公司 | 制备环己基苯的工艺 |
US20090305317A1 (en) * | 2008-06-05 | 2009-12-10 | Brauer Jacob S | User interface for testing device |
CN102216215B (zh) * | 2008-07-28 | 2014-03-26 | 埃克森美孚化学专利公司 | 使用emm-12制备烷基芳族化合物的方法 |
CN102333747A (zh) | 2009-02-26 | 2012-01-25 | 埃克森美孚化学专利公司 | 生产环己基苯的方法 |
US8500990B2 (en) * | 2009-04-22 | 2013-08-06 | Nova Biomedical Corporation | Electrochemical biosensors based on NAD(P)-dependent dehydrogenase enzymes |
US8633343B2 (en) | 2009-05-26 | 2014-01-21 | Exxonmobil Chemical Patents Inc. | Transalkylation of polycyclohexylbenzenes |
CA2888743C (en) | 2012-10-17 | 2024-01-02 | University Of Maryland, Office Of Technology Commercialization | Device and methods of using device for detection of aminoacidopathies |
EP3132049B1 (de) * | 2014-04-17 | 2021-08-25 | University of Maryland, College Park | Vorrichtung und verfahren zur verwendung der vorrichtung für den nachweis von aminoazidopathien |
WO2016176366A1 (en) | 2015-04-27 | 2016-11-03 | University Of Maryland, College Park | Device and methods of using device for detection of hyperammonemia |
CN112840210B (zh) * | 2018-09-06 | 2024-09-06 | 澳科环球有限公司 | 用于确定分析物浓度的系统、传感器和方法 |
WO2021245040A1 (en) | 2020-06-01 | 2021-12-09 | Gambro Lundia Ab | System and method for extracorporeal blood treatment |
CN116018084A (zh) * | 2020-09-18 | 2023-04-25 | 美敦力迷你迈德公司 | 酮体感测装置和方法 |
CN114965641B (zh) * | 2022-05-23 | 2024-05-28 | 可孚医疗科技股份有限公司 | 一种β-羟丁酸电化学试纸、制备方法及应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4147514A (en) * | 1977-11-21 | 1979-04-03 | Miles Laboratories, Inc. | Test means and method for detecting ketone bodies |
US4254222A (en) * | 1978-07-19 | 1981-03-03 | Owen Oliver E | Semi-quantitative assay of lactic acid and β-hydroxy butyrate |
US4351899A (en) * | 1978-07-19 | 1982-09-28 | Owen Oliver E | Semi-quantitative assay of metabolic acids |
US4288541A (en) * | 1979-10-15 | 1981-09-08 | Miles Laboratories, Inc. | Ascorbate resistant composition, test device and method for detecting a component in a liquid test sample |
US4318984A (en) * | 1979-11-13 | 1982-03-09 | Miles Laboratories, Inc. | Stabilized composition, test device, and method for detecting the presence of a sugar in a test sample |
US4279993A (en) * | 1979-11-13 | 1981-07-21 | Magers Thomas A | Indicator composition and test device containing amine oxide, and method of use |
US4290773A (en) * | 1979-11-13 | 1981-09-22 | Miles Laboratories, Inc. | Stabilization of benzidine-type indicators with various enhancers |
JPS6091998A (ja) * | 1983-10-27 | 1985-05-23 | Yukio Shigeta | 体液及び尿中のd―3―ヒドロキシ酪酸の測定法並びにそのための測定試薬 |
JPS60180600A (ja) * | 1984-02-29 | 1985-09-14 | Kyowa Medetsukusu Kk | 還元型ニコチンアミド・アデニン・ジヌクレオチドの定量方法 |
JPH0698029B2 (ja) * | 1985-12-10 | 1994-12-07 | 株式会社三和化学研究所 | 獣乳の品質検査と乳獣の健康診断とを同時に行う方法 |
US5041658A (en) * | 1986-04-04 | 1991-08-20 | Miles Inc. | Carboxamido nitrobenzene disulfide compound |
US4975367A (en) * | 1986-04-04 | 1990-12-04 | Miles Inc. | Catalytic test composition intended to produce a range of colors |
US4898813A (en) * | 1986-04-04 | 1990-02-06 | Albarella James P | Catalytic test composition intended to produce a range of colors |
DE3703081A1 (de) * | 1987-02-03 | 1988-08-11 | Miles Inc | Verfahren und mittel zum nachweis von thiolen |
CA1340759C (en) * | 1988-07-01 | 1999-09-21 | James P. Albarella | Isobenzothiazolone chromogenic thiol indicators and their derivatives |
US5190863A (en) * | 1990-06-29 | 1993-03-02 | Miles Inc. | Composition for determining the presence or concentration of D-β-hydroxybutyrate |
-
1990
- 1990-06-29 US US07/545,634 patent/US5190863A/en not_active Expired - Lifetime
-
1991
- 1991-05-15 CA CA002042645A patent/CA2042645A1/en not_active Abandoned
- 1991-06-15 DE DE69117588T patent/DE69117588T2/de not_active Expired - Fee Related
- 1991-06-15 AT AT91109858T patent/ATE135052T1/de not_active IP Right Cessation
- 1991-06-15 EP EP91109858A patent/EP0463524B1/de not_active Expired - Lifetime
- 1991-06-15 ES ES91109858T patent/ES2084061T3/es not_active Expired - Lifetime
- 1991-06-15 DK DK91109858.0T patent/DK0463524T3/da active
- 1991-06-21 AU AU79261/91A patent/AU628751B2/en not_active Ceased
- 1991-06-28 JP JP03184189A patent/JP3118029B2/ja not_active Expired - Fee Related
-
1992
- 1992-09-08 US US07/941,707 patent/US5326697A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU7926191A (en) | 1992-01-02 |
US5190863A (en) | 1993-03-02 |
ES2084061T3 (es) | 1996-05-01 |
EP0463524B1 (de) | 1996-03-06 |
ATE135052T1 (de) | 1996-03-15 |
AU628751B2 (en) | 1992-09-17 |
JPH04237500A (ja) | 1992-08-25 |
EP0463524A1 (de) | 1992-01-02 |
US5326697A (en) | 1994-07-05 |
CA2042645A1 (en) | 1991-12-30 |
JP3118029B2 (ja) | 2000-12-18 |
DE69117588T2 (de) | 1996-10-10 |
DK0463524T3 (da) | 1996-07-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |