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DE69115990D1 - Zusammensetzung zur Behandlung von Dry Eye Erkrankungen - Google Patents

Zusammensetzung zur Behandlung von Dry Eye Erkrankungen

Info

Publication number
DE69115990D1
DE69115990D1 DE69115990T DE69115990T DE69115990D1 DE 69115990 D1 DE69115990 D1 DE 69115990D1 DE 69115990 T DE69115990 T DE 69115990T DE 69115990 T DE69115990 T DE 69115990T DE 69115990 D1 DE69115990 D1 DE 69115990D1
Authority
DE
Germany
Prior art keywords
composition
treatment
dry eye
eye diseases
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69115990T
Other languages
English (en)
Other versions
DE69115990T2 (de
Inventor
Thomas Glonek
Donald Korb
Jack V Greiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OCULAR RES OF BONTON Inc
Original Assignee
OCULAR RES OF BONTON Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OCULAR RES OF BONTON Inc filed Critical OCULAR RES OF BONTON Inc
Application granted granted Critical
Publication of DE69115990D1 publication Critical patent/DE69115990D1/de
Publication of DE69115990T2 publication Critical patent/DE69115990T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
DE69115990T 1990-05-29 1991-04-25 Zusammensetzung zur Behandlung von Dry Eye Erkrankungen Expired - Lifetime DE69115990T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52965790A 1990-05-29 1990-05-29
US63821591A 1991-01-07 1991-01-07

Publications (2)

Publication Number Publication Date
DE69115990D1 true DE69115990D1 (de) 1996-02-15
DE69115990T2 DE69115990T2 (de) 1996-05-30

Family

ID=27063077

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69115990T Expired - Lifetime DE69115990T2 (de) 1990-05-29 1991-04-25 Zusammensetzung zur Behandlung von Dry Eye Erkrankungen

Country Status (12)

Country Link
US (1) US5294607A (de)
EP (1) EP0459148B1 (de)
JP (1) JP3281392B2 (de)
AT (1) ATE132366T1 (de)
AU (1) AU648304B2 (de)
CA (1) CA2043366C (de)
DE (1) DE69115990T2 (de)
ES (1) ES2084722T3 (de)
GR (1) GR3019478T3 (de)
IL (1) IL98237A (de)
RU (1) RU2092138C1 (de)
TW (1) TW200396B (de)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364632A (en) * 1989-04-05 1994-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
ZA927277B (en) * 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
EP0733918B1 (de) * 1995-03-24 2003-07-30 Ocular Research of Boston, Inc. Hydrogellinse mit Lipid-Vorbeschichtigung
DE19511322C2 (de) 1995-03-28 1999-09-02 Mann Gerhard Chem Pharm Fab Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung
US5616342A (en) * 1995-04-11 1997-04-01 Pdt, Inc. Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof
DE19527132A1 (de) * 1995-07-25 1997-01-30 Laevosan Gmbh & Co Kg Ophthalmologische Ozonschutzzusammensetzung
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
JPH10218760A (ja) * 1997-02-04 1998-08-18 Nobel Igaku Kenkyusho:Kk ドライアイ治療用の微量油添加目薬
ZA989513B (en) 1997-10-21 1999-04-21 Alcon Lab Inc Compositions containing histamine H2 agonists and methods of use in treating dry eye
RU2125427C1 (ru) * 1998-05-27 1999-01-27 Миронова Эмилия Михайловна Средство для лечения глазных заболеваний - оковидит
EP0982025A1 (de) * 1998-08-28 2000-03-01 Wilhelm Prof. Dr. Stoffel Künstliche Tränen
US6462080B1 (en) 1998-12-24 2002-10-08 Alcon Manufacturing, Ltd. Prostaglandin E receptor agonists for treatment of dry eye
WO2000038663A2 (en) 1998-12-24 2000-07-06 Alcon Laboratories, Inc. Ep4 receptor agonists for treatment of dry eye
US6281192B1 (en) 1999-03-01 2001-08-28 Vista Scientific Llc Mucin containing ophthalmic preparations
AUPQ228199A0 (en) * 1999-08-18 1999-09-09 Sly, Anthony William Ophthalmic fluid
US6353032B1 (en) 1999-11-09 2002-03-05 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
US6552084B2 (en) 1999-11-09 2003-04-22 Alcon Universal Ltd. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
AU8031400A (en) 1999-11-09 2001-06-06 Alcon Universal Limited 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders
KR20020050240A (ko) 1999-11-09 2002-06-26 구이도 콜러, 스테판 바슬러 하이드록시에이코사테트라에노에이트 염, 조성물 및 안구건조증 치료에서의 사용 방법
BR0015392A (pt) * 1999-11-09 2002-06-25 Alcon Inc Lipoxina a4 e seus análogos para o tratamento de olho ressecado
ATE296792T1 (de) 1999-11-09 2005-06-15 Alcon Inc Benzenoidderivate von 15- hydroxyeicosatetraensäure und verfahren zur verwendung zur behandlung des trockenen auges
HK1045984B (en) 1999-11-09 2004-04-23 Alcon, Inc. Omega chain modified 15-hydroxyeicosatetraenoic acid derivative is suitable for the treatment of dry eye
US6803385B2 (en) 1999-11-09 2004-10-12 Alcon, Inc. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
AU1101301A (en) 1999-11-09 2001-06-06 Alcon Universal Limited 2,2-difluoro 15-hydroxyeicosatetraenoic acid analogs and methods of use
HK1045986B (en) 1999-11-09 2004-12-24 Alcon, Inc. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
KR20020050238A (ko) 1999-11-09 2002-06-26 구이도 콜러, 스테판 바슬러 15-하이드록시에이코사테트라엔산-관련 화합물 및 사용 방법
BR0015423A (pt) 1999-11-09 2002-07-09 Alcon Inc Análogos de ácido 15-hidroxieicosatetraenóico interrompidos por heteroátomo e métodos de uso
DE60010503T2 (de) 1999-11-09 2004-09-23 Alcon, Inc. Tri-heteroatom-substituierte und zwei kohlenstoff homologe von 15-hete und verfahren zur verwendung
US6458854B2 (en) 1999-11-09 2002-10-01 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
US6576663B2 (en) 1999-12-22 2003-06-10 Alcon, Inc. 6-Keto prostaglandin F1α and analogs for treating dry eye
US6348508B1 (en) 2000-04-04 2002-02-19 Bausch & Lomb Incorporated Method for treating dry eye
JP2004502497A (ja) * 2000-07-12 2004-01-29 ルージュ ヴァリー ナチュラル スプリングス インコーポレイテッド 眼の表面を湿らせる方法及びキット
US7524511B1 (en) * 2000-07-12 2009-04-28 Rogue Valley Natural Springs, Inc. Method and kit for moisturizing the surface of the eye
US7112588B2 (en) * 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
CA2447918A1 (en) * 2001-05-21 2002-11-28 Alcon, Inc. Method of treating dry eye disorders
US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
WO2002095704A1 (en) 2001-05-21 2002-11-28 Alcon, Inc. Use of nf-kappa-b inhibitors to treat dry eye disorders
MXPA03010634A (es) 2001-05-21 2004-03-09 Alcon Inc Uso de inhibidores de proteasoma para tratar trastornos del ojo seco.
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
FR2827190A1 (fr) * 2001-06-22 2003-01-17 Rhodia Chimie Sa Utilisation d'une huile comprenant un groupement polaire comme aide au depot d'une huile polaire non ionisable
US6750250B1 (en) * 2001-07-12 2004-06-15 Alcon, Inc. 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
DE10141018A1 (de) * 2001-08-22 2003-03-13 Eth Zuerich Eidgenoessische Te Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges
AR035293A1 (es) * 2001-08-23 2004-05-05 Novartis Ag Composicion oftalmica.
US20040220089A1 (en) * 2001-10-03 2004-11-04 Ellis Edward J. Ophthalmic preparation containing glycoprotein
US20040214754A1 (en) * 2001-10-03 2004-10-28 Ellis Edward J. Ophthalmic preparation containing glycomacropeptide
CA2462272A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye by a combination of an antiinflammatory steroid and a muc-1 secretagogue
WO2003030894A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
US6656460B2 (en) * 2001-11-01 2003-12-02 Yissum Research Development Method and composition for dry eye treatment
AU782913B2 (en) * 2001-11-02 2005-09-08 Santen Sas Method and composition for dry eye treatment
WO2003096991A2 (en) * 2002-05-17 2003-11-27 Othera Pharmaceuticals, Inc. Amelioration of the development of cataracts and other opthalmic diseases
RU2232582C2 (ru) * 2002-07-29 2004-07-20 Уфимский научно-исследовательский институт глазных болезней Глазная пленка
MXPA05003063A (es) * 2002-09-20 2005-05-27 Alcon Inc Uso de inhibidores de la sintesis de citosina para el tratamiento de trastornos de ojos secos.
AU2003303623A1 (en) * 2002-12-20 2004-07-29 Alcon, Inc. Treatment of dry eye by restoring 15-lipoxygenase activity to ocular surface cells
WO2004093878A1 (en) 2003-04-16 2004-11-04 Alcon, Inc. Use of fused pyridazine derivatives for treating dry eye disorders
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
RU2245137C1 (ru) * 2003-06-18 2005-01-27 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Фармацевтическая композиция для лечения воспалительных процессов вирусной этиологии в глазном яблоке
WO2005025539A1 (ja) * 2003-09-10 2005-03-24 Senju Pharmaceutical Co., Ltd. コンタクトレンズ用眼科用組成物
MXPA03011987A (es) 2003-12-19 2005-06-23 Osio Sancho Alberto Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal.
CA2552524A1 (en) * 2004-01-10 2005-07-28 Biolipid, Inc. Lipid compositions and methods of use
US20050182039A1 (en) * 2004-02-13 2005-08-18 Bausch & Lomb Incorporated Use of Loteprednol etabonate for the treatment of dry eye
AU2005229006B9 (en) 2004-03-25 2011-05-19 Bausch & Lomb Incorporated Use of loteprednol etabonate for the treatment of dry eye
US20050256189A1 (en) * 2004-05-14 2005-11-17 Alcon, Inc. Method of treating dry eye disorders and uveitis
US7923471B2 (en) * 2004-05-14 2011-04-12 Alcon, Inc. Method of treating dry eye disorders and uveitis
US20060009522A1 (en) * 2004-07-01 2006-01-12 Reza Dana Compositions and methods for treating eye disorders and conditions
JP5272307B2 (ja) * 2004-07-16 2013-08-28 大正製薬株式会社 水性点眼剤
US7223737B1 (en) 2004-08-13 2007-05-29 Alcon, Inc. Method of treating dry eye disorders using glycosides
US20070265353A1 (en) 2004-08-27 2007-11-15 Senju Pharmaceutical Co., Ltd. Eye Drops for the Treatment of Dry Eye
WO2006065916A1 (en) * 2004-12-14 2006-06-22 Alcon, Inc. Method of treating dry eye disorders using 13(s)-hode and its analogs
US9161905B2 (en) * 2005-01-12 2015-10-20 Ocular Research Of Boston, Inc. Dry eye treatment
AU2012201476B2 (en) * 2005-01-12 2014-07-17 Ocular Research Of Boston, Inc Dry eye treatment
TW200722109A (en) * 2005-03-31 2007-06-16 Bausch & Lomb Polysaccharide and polyol composition for treating dry eye and related methods of manufacture and methods of use
TWI393567B (zh) * 2005-03-31 2013-04-21 Bausch & Lomb 治療乾眼之組合物及相關之製造方法及使用方法
SI1888059T1 (sl) 2005-06-01 2015-05-29 Edison Pharmaceuticals, Inc. Redoks-aktivni terapevtiki za zdravljenje mitohondrijskih bolezni in drugih bolezni ter modulacijo energijskih biooznaäśevalcev
US20070004672A1 (en) * 2005-07-01 2007-01-04 Dharmendra Jani Long lasting alginate dry eye, related methods of manufacture and methods of use
US20070110812A1 (en) * 2005-11-14 2007-05-17 Bausch & Lomb Incorporated Ophthalmic composition for dry eye therapy
JP6033177B2 (ja) * 2006-01-13 2016-11-30 大正製薬株式会社 O/w型エマルション水性点眼剤
JP5748385B2 (ja) * 2006-01-13 2015-07-15 大正製薬株式会社 O/w型エマルション水性点眼剤
EA019675B1 (ru) 2006-02-22 2014-05-30 Эдисон Фармасьютикалз, Инк. Редокс-активные терапевтические средства для лечения митохондриальных заболеваний и модуляции биомаркера коэнзима q
US7745461B1 (en) 2006-02-27 2010-06-29 Alcon Research, Ltd. Method of treating dry eye disorders
ES2284398B2 (es) 2006-04-27 2008-12-16 Universidad Complutense De Madrid Formulacion de vesiculas liposomales en soluciones acuosas con caracteristicas de pelicula lagrimal.
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
CA2650478C (en) * 2006-07-07 2013-08-13 Bausch & Lomb Incorporated Compositions comprising a dissociated glucocorticoid receptor agonist and an immunosuppressive agent for treating dry eye
US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
US20080095754A1 (en) * 2006-10-18 2008-04-24 Burke Susan E Ophthalmic compositions comprising diglycine
US8138156B2 (en) * 2006-10-18 2012-03-20 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
WO2008052031A2 (en) * 2006-10-24 2008-05-02 Alcon Research, Ltd. 2-pyrrolidone derivatives for preservation of ophthalmic, otic and nasal compositions
US20080093247A1 (en) * 2006-10-24 2008-04-24 Alcon Manufacturing Ltd. Packaging materials for formulations containing 2-pyrrolidone derivatives
US20080188573A1 (en) * 2007-02-02 2008-08-07 Alcon Research, Ltd. Use of thy1-fp transgenic mouse for the identification of ophthalmic agents
WO2008120249A1 (en) * 2007-03-30 2008-10-09 Sifi S.P.A. Pharmaceutical formulations based on apolar and polar lipids for ophthalmic use
ES2396999T3 (es) * 2007-05-04 2013-03-01 Bausch & Lomb Incorporated Composiciones para la reducción, mejora, tratamiento, o prevención de la afección de ojo seco y métodos de elaboración y de uso de las mismas
CA2686866A1 (en) * 2007-05-07 2008-11-13 Erning Xia Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same
WO2008154129A1 (en) * 2007-06-08 2008-12-18 Bausch & Lomb Incorporated Pharmaceutical compositions and method for treating, reducing, ameliorating, alleviating, or preventing dry eye
US20090142292A1 (en) * 2007-12-03 2009-06-04 Blackwell Richard I Method For The Mitigation of Symptoms of Dry Eye
US8629099B2 (en) * 2008-03-25 2014-01-14 Bausch & Lomb Incorporated Ophthalmic compositions comprising a dipeptide
EP2344142B1 (de) 2008-09-10 2024-06-26 PTC Therapeutics, Inc. Behandlung von pervasiven entwicklungsstörungen mit redox-aktiven therapeutika
WO2010030725A1 (en) * 2008-09-15 2010-03-18 Bausch & Lomb Incorporated Compositions comprising polymers having amino sugar units and methods of making and using same
US8539938B2 (en) * 2009-03-12 2013-09-24 Ford Global Technologies, Llc Fuel systems and methods for controlling fuel systems in a vehicle with multiple fuel tanks
JP2012525399A (ja) 2009-04-28 2012-10-22 エジソン ファーマシューティカルズ, インコーポレイテッド トコトリエノールキノンを用いる、レーバー遺伝性視神経症および優性遺伝性視神経萎縮症の治療
TWI478730B (zh) 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
US8658614B2 (en) 2010-08-13 2014-02-25 The University of Texas Health Science Center Aptamer-containing compositions and methods for targeting E-selectin
US9161531B2 (en) 2011-02-23 2015-10-20 Donald R. Korb High alcohol content sanitizer
US8859525B2 (en) 2011-07-19 2014-10-14 Bausch & Lomb Incorporated Pharmaceutical compositions comprising mushroom-based polysaccharides and uses thereof
CA2851492A1 (en) 2011-09-22 2013-03-28 Bausch & Lomb Incorporated Ophthalmic gel compositions
US8324171B1 (en) 2012-02-06 2012-12-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US8664180B2 (en) 2012-02-06 2014-03-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US9278132B2 (en) 2012-02-13 2016-03-08 Bausch & Lomb Incorporated Ophthalmic pharmaceutical compositions and methods of making and using same
US9375401B2 (en) 2012-02-24 2016-06-28 Bausch ÷ Lomb Incorporated Ophthalmic compositions with alkoxylated natural waxes
JP6016465B2 (ja) * 2012-06-12 2016-10-26 ロート製薬株式会社 ビタミンa類を含有する水性組成物
KR102184340B1 (ko) 2012-08-10 2020-12-01 오시오 코포레이션 디/비/에이 율리아 헬스 안과적 상태 치료시의 컨택트 렌즈 사용
WO2014116787A1 (en) 2013-01-24 2014-07-31 Bausch & Lomb Incorporated Poly(nitrogen/amine) derivatives of a natural wax and ophthalmic compositions
US10302658B2 (en) 2014-03-12 2019-05-28 University Of Virginia Patent Foundation Compositions and methods for treating eye infections and disease
EP3140316A1 (de) 2014-05-05 2017-03-15 Thetis Pharmaceuticals LLC Zusammensetzungen und verfahren im zusammenhang mit ionischen salzen von peptiden
CN107074884A (zh) 2014-06-18 2017-08-18 西蒂斯制药有限责任公司 活性剂的矿物质氨基酸复合物
JP7002756B2 (ja) 2015-11-05 2022-01-20 ユニバーシティー オブ ルイヴィル リサーチ ファウンデーション,インコーポレーテッド 局所と局部の麻酔と鎮痛
JP6905527B2 (ja) 2015-12-17 2021-07-21 ピーティーシー セラピューティクス, インコーポレイテッド 酸化ストレス障害を処置するためのフルオロアルキル、フルオロアルコキシ、フェノキシ、ヘテロアリールオキシ、アルコキシ、およびアミノ1,4−ベンゾキノン誘導体
CN109562186B (zh) 2016-06-03 2022-09-13 西蒂斯制药有限责任公司 与专门促消退介质的盐有关的组合物和方法
US9981041B2 (en) 2016-08-23 2018-05-29 Ira Jason Salzman Ophthalmic lubricating spray
US12233017B2 (en) 2016-10-14 2025-02-25 Olympic Ophthalmics, Inc. Quiet handheld devices and methods for treatment of disorders
US20180296390A1 (en) * 2017-04-18 2018-10-18 David Hoare Apparatus and method for treating a number of eye conditions of a user including dry eye syndrome and/or burns to the eyes
KR102691673B1 (ko) 2018-02-21 2024-08-06 알콘 인코포레이티드 지질-기재 안과용 에멀션
US11141348B2 (en) 2018-02-26 2021-10-12 Olympic Ophthalmics, Inc. Treatment methods using handheld devices for disorders
CN113423387A (zh) * 2018-12-10 2021-09-21 埃特娜蒂尔公司 提供持久眼部润滑的眼用制剂
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677099A (en) * 1981-09-04 1987-06-30 Yeda Research And Development Co., Ltd. Medical processes employing a novel lipid fraction
US4421748A (en) * 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
US4839175A (en) * 1986-07-28 1989-06-13 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
WO1988000824A1 (en) * 1986-07-28 1988-02-11 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
US4804539A (en) * 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
US4818537A (en) * 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
US4914088A (en) * 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US4866049A (en) * 1987-08-10 1989-09-12 Spectra Pharmaceutical Services, Inc. Ophthalmic compositionn and method of using same
AU614465B2 (en) * 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions

Also Published As

Publication number Publication date
GR3019478T3 (en) 1996-07-31
AU648304B2 (en) 1994-04-21
RU2092138C1 (ru) 1997-10-10
AU7619191A (en) 1992-08-06
EP0459148A3 (en) 1992-10-14
CA2043366C (en) 1999-01-05
ES2084722T3 (es) 1996-05-16
JP3281392B2 (ja) 2002-05-13
CA2043366A1 (en) 1991-11-30
US5294607A (en) 1994-03-15
TW200396B (de) 1993-02-21
DE69115990T2 (de) 1996-05-30
ATE132366T1 (de) 1996-01-15
IL98237A (en) 1996-08-04
EP0459148A2 (de) 1991-12-04
IL98237A0 (en) 1992-06-21
EP0459148B1 (de) 1996-01-03
JPH04279525A (ja) 1992-10-05

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