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DE69104539D1 - Granulare Zubereitungen und Verfahren zur ihrer Herstellung. - Google Patents

Granulare Zubereitungen und Verfahren zur ihrer Herstellung.

Info

Publication number
DE69104539D1
DE69104539D1 DE69104539A DE69104539A DE69104539D1 DE 69104539 D1 DE69104539 D1 DE 69104539D1 DE 69104539 A DE69104539 A DE 69104539A DE 69104539 A DE69104539 A DE 69104539A DE 69104539 D1 DE69104539 D1 DE 69104539D1
Authority
DE
Germany
Prior art keywords
fatty acid
acid ester
polyglycerol fatty
active ingredient
pharmacologically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69104539A
Other languages
English (en)
Other versions
DE69104539T2 (de
DE69104539T4 (de
Inventor
Minoru Yoshioka
Toshio Kashihara
Hidetoshi Horibe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69104539D1 publication Critical patent/DE69104539D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/30—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using agents to prevent the granules sticking together; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/20—Agglomerating; Granulating; Tabletting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Glanulating (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69104539A 1990-04-28 1991-04-22 Granulare Zubereitungen und Verfahren zur ihrer Herstellung. Expired - Fee Related DE69104539D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11438290 1990-04-28

Publications (1)

Publication Number Publication Date
DE69104539D1 true DE69104539D1 (de) 1994-11-17

Family

ID=14636279

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69104539A Expired - Fee Related DE69104539D1 (de) 1990-04-28 1991-04-22 Granulare Zubereitungen und Verfahren zur ihrer Herstellung.
DE69104539T Expired - Lifetime DE69104539T4 (de) 1990-04-28 1991-04-22 Granulare Zubereitungen und Verfahren zur ihrer Herstellung.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69104539T Expired - Lifetime DE69104539T4 (de) 1990-04-28 1991-04-22 Granulare Zubereitungen und Verfahren zur ihrer Herstellung.

Country Status (10)

Country Link
US (1) US5443846A (de)
EP (1) EP0455391B1 (de)
JP (1) JP3124063B2 (de)
KR (1) KR0171218B1 (de)
AT (1) ATE112675T1 (de)
CA (1) CA2041378C (de)
DE (2) DE69104539D1 (de)
DK (1) DK0455391T3 (de)
ES (1) ES2061179T3 (de)
IE (1) IE65045B1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW209174B (de) 1991-04-19 1993-07-11 Takeda Pharm Industry Co Ltd
TW282403B (de) * 1993-08-26 1996-08-01 Takeda Pharm Industry Co Ltd
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
SE511313C2 (sv) * 1997-01-13 1999-09-06 Gs Dev Ab Komposition med reglerad frisättning innefattande fettsyraester av diacylglycerol
CN1252711A (zh) * 1997-04-18 2000-05-10 大正制药株式会社 微乳
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
US20020029520A1 (en) * 1998-05-21 2002-03-14 Weder Donald E. Decorative attachments and methods of use
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
JP4974419B2 (ja) * 2001-06-12 2012-07-11 東和薬品株式会社 薬物含有徐放性顆粒およびそれを含む錠剤
SE0200154D0 (sv) 2002-01-21 2002-01-21 Galenica Ab New process
US20050031686A1 (en) * 2002-03-25 2005-02-10 Truffini & Regge' Farmaceutici Srl Gastroresistant tablets for alimentary, dietetic and therapeutic use
PL206594B1 (pl) 2002-07-15 2010-08-31 Alcon Kompozycja implantu śródocznego i zastosowanie leku oftalmicznego w połączeniu z niskocząsteczkowym związkiem lipofilowym do jej wytwarzania
EP1640006A4 (de) * 2003-06-27 2012-04-04 Otsuka Pharma Co Ltd Teilchen mit verzögerter arzneimittelfreisetzung und herstellungsverfahren dafür
US20070059358A1 (en) * 2003-07-02 2007-03-15 Tianjin Tasly Pharmaceutical Co., Ltd., China Matrix adjuvants and the drop pills prepared with them
US7364755B2 (en) * 2003-07-07 2008-04-29 Synthon Ip Inc. Modified calcium phosphate excipient
DE102004049241A1 (de) * 2004-10-09 2006-04-20 Sanofi-Aventis Deutschland Gmbh Trockner und Verfahren zum Steuern eines Trockners
US20060275228A1 (en) * 2005-05-09 2006-12-07 Bissett Donald L Skin care compositions containing idebenone
EP2502621A1 (de) 2005-06-27 2012-09-26 Valeant International (Barbados) SRL Kristalline Formen von Bupropion HBr
WO2007022092A1 (en) * 2005-08-15 2007-02-22 Stepan Company High melt lipids
CA2649619C (en) * 2006-04-17 2012-08-28 Meiji Seika Kaisha, Ltd. Whey protein-containing granules and method of producing the same
JP5256041B2 (ja) * 2006-10-31 2013-08-07 株式会社カネカ 生理活性物質含有粒子状組成物およびその製造方法
US20090246276A1 (en) 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
US8287902B2 (en) * 2008-07-23 2012-10-16 Rainbow Medical Ltd. Enhanced-diffusion capsule
JP5230308B2 (ja) * 2008-09-04 2013-07-10 協友アグリ株式会社 溶出が制御された農薬製剤
KR101159890B1 (ko) * 2008-12-22 2012-06-25 주식회사 삼양웰푸드 분말 유지 조성물
US8227399B2 (en) * 2010-02-12 2012-07-24 Evonik Goldschmidt Gmbh Polyglycerol esters and their use
JP5650956B2 (ja) * 2010-08-31 2015-01-07 株式会社ファンケル 混合顆粒剤の製造方法
US9353301B2 (en) * 2013-11-25 2016-05-31 Ecolab Usa Inc. Composition for dust control
JP6178233B2 (ja) * 2013-12-25 2017-08-09 三井化学アグロ株式会社 徐放性農薬製剤及びその製造方法
US9492396B2 (en) 2014-07-15 2016-11-15 Yossi Gross Enhanced drug delivery pill
EP3703724A1 (de) 2017-11-02 2020-09-09 NatureCeuticals Sdn. Bhd. Extrakt aus orthosiphon stamineus, formulierungen und verwendungen davon
US10675248B2 (en) 2018-08-14 2020-06-09 Alma Therapeutics Ltd. Expandable pill
WO2025032355A1 (de) * 2023-08-04 2025-02-13 Ioi Oleo Gmbh Grundlage für suppositorien oder ovula sowie darauf basierende suppositorien- oder ovulamasse und deren verwendung in einem herstellungsverfahren

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH574245A5 (de) * 1971-06-04 1976-04-15 Boehringer Mannheim Gmbh
US3936391A (en) * 1971-06-16 1976-02-03 Drackett Company Hydrated polyglycerol ester composition
DE2143519B2 (de) * 1971-08-31 1974-05-30 Sandoz Ag, 8500 Nuernberg Verfahren zur Wirbelschichtgranulation pulverförmiger pharmazeutischer Mischungen
JPS4856577A (de) * 1971-11-22 1973-08-08
DE2426812A1 (de) * 1974-06-04 1976-01-02 Klinge Co Chem Pharm Fab Verfahren zur herstellung von granulaten
US4386120A (en) * 1980-01-07 1983-05-31 Nippon Kayaku Kabushiki Kaisha Process for producing polyacrylic acid salt granules easily soluble in water
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
DE3224619A1 (de) * 1981-07-14 1983-05-19 Freund Industrial Co., Ltd., Tokyo Orale pharmazeutische zusammensetzung
JPS58214333A (ja) * 1982-06-04 1983-12-13 Dai Ichi Seiyaku Co Ltd 粒状物
JPS5944327A (ja) * 1982-09-06 1984-03-12 Taiyo Kagaku Kk Ｌ−アスコルビン酸およびその塩類の安定化法
US4904478A (en) * 1983-08-11 1990-02-27 Mission Pharmacal Company Slow-release sodium fluoride tablet and method for treatment of osteoporosis
US4894233A (en) * 1984-10-05 1990-01-16 Sharma Shri C Novel drug delivery system for decongestants
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
US4820523A (en) * 1986-04-15 1989-04-11 Warner-Lambert Company Pharmaceutical composition
DE3702029A1 (de) * 1987-01-24 1988-08-04 Basf Ag Waessriges oder pulverfoermiges, wasserdispergierbares praeparat eines in wasser schwerloeslichen pharmazeutischen wirkstoffs und verfahren zu seiner herstellung
JP2547995B2 (ja) * 1987-01-26 1996-10-30 昭和電工株式会社 反すう動物用粒剤及びその製造法
DE3721721C1 (de) * 1987-07-01 1988-06-09 Hoechst Ag Verfahren zur Umhuellung von Granulaten
DE3837628A1 (de) * 1988-11-05 1990-05-10 Broesamle Peter Verfahren und vorrichtung zur behandlung von organischen schlaemmen
AU645003B2 (en) * 1988-11-08 1994-01-06 Takeda Chemical Industries Ltd. Sustained release preparations
CA1331713C (en) * 1988-12-29 1994-08-30 Hitoshi Iijima Granular composition for ruminant
US5017383A (en) * 1989-08-22 1991-05-21 Taisho Pharmaceutical Co., Ltd. Method of producing fine coated pharmaceutical preparation
US5169645A (en) * 1989-10-31 1992-12-08 Duquesne University Of The Holy Ghost Directly compressible granules having improved flow properties

Also Published As

Publication number Publication date
EP0455391B1 (de) 1994-10-12
IE911276A1 (en) 1991-11-06
DE69104539T2 (de) 1995-03-23
KR0171218B1 (ko) 1999-01-15
ATE112675T1 (de) 1994-10-15
DK0455391T3 (da) 1995-03-13
EP0455391A2 (de) 1991-11-06
US5443846A (en) 1995-08-22
JPH05237A (ja) 1993-01-08
JP3124063B2 (ja) 2001-01-15
IE65045B1 (en) 1995-10-04
CA2041378A1 (en) 1991-10-29
EP0455391A3 (de) 1991-12-18
DE69104539T4 (de) 1995-07-27
ES2061179T3 (es) 1994-12-01
CA2041378C (en) 2002-02-12
KR910018069A (ko) 1991-11-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee