DE69033603D1 - Antagonisten von wachstumshormonen - Google Patents

Antagonisten von wachstumshormonen

Info

Publication number: DE69033603D1
Authority: DE; Germany
Prior art keywords: antagonists; growth hormones; growth; animals; antagonist
Prior art date: 1989-10-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69033603T

Other languages

English (en)

Other versions

DE69033603T2 (de

Inventor

J Kopchick

Y Chen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ohio University

Original Assignee

Ohio University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-12

Filing date

1990-10-12

Publication date

2000-09-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23662783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69033603(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-10-12 Application filed by Ohio University filed Critical Ohio University

2000-09-14 Application granted granted Critical

2000-09-14 Publication of DE69033603D1 publication Critical patent/DE69033603D1/de

2001-04-12 Publication of DE69033603T2 publication Critical patent/DE69033603T2/de

2010-10-13 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Zoology (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Environmental Sciences (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Biodiversity & Conservation Biology (AREA)
Biophysics (AREA)
Animal Husbandry (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Physics & Mathematics (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DE69033603T 1989-10-12 1990-10-12 Antagonisten von wachstumshormonen Expired - Lifetime DE69033603T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US41956189A	1989-10-12	1989-10-12
PCT/US1990/005874 WO1991005853A1 (en)	1989-10-12	1990-10-12	Growth hormone antagonists

Publications (2)

Publication Number	Publication Date
DE69033603D1 true DE69033603D1 (de)	2000-09-14
DE69033603T2 DE69033603T2 (de)	2001-04-12

Family

ID=23662783

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69033603T Expired - Lifetime DE69033603T2 (de)	1989-10-12	1990-10-12	Antagonisten von wachstumshormonen

Country Status (10)

Country	Link
EP (1)	EP0556171B1 (de)
JP (1)	JP3789928B2 (de)
AT (1)	ATE195339T1 (de)
AU (1)	AU652545B2 (de)
CA (1)	CA2067136C (de)
DE (1)	DE69033603T2 (de)
DK (1)	DK0556171T3 (de)
ES (1)	ES2150901T3 (de)
GR (1)	GR3034743T3 (de)
WO (1)	WO1991005853A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2062572T3 (es) *	1989-07-10	1994-12-16	Upjohn Co	Analogos de somatotropina.
US5350836A (en) *	1989-10-12	1994-09-27	Ohio University	Growth hormone antagonists
US5310882A (en) *	1990-11-30	1994-05-10	American Cyanamid Company	Somatotropins with alterations in the α-helix 3 region
CA2102129C (en) *	1991-05-01	2003-04-01	John J. Kopchick	Growth hormone antagonists
US5506107A (en) *	1991-05-10	1996-04-09	Genentech, Inc.	Selecting ligand agonists and antagonists
US6429186B1 (en)	1991-05-10	2002-08-06	Genentech, Inc.	Ligand antagonists for treatment of breast cancer
ATE314479T1 (de) *	1992-05-18	2006-01-15	Genentech Inc	Aktivierung von rezeptoren fähig zur oligomerisierung durch verwendung von fusionierten rezeptor liganden
US5684136A (en) *	1992-05-18	1997-11-04	Genentech, Inc.	Chimeric hepatocyte growth factor (HGF) ligand variants
WO1999051627A1 (fr) *	1998-04-04	1999-10-14	Nakoshi, Hideo	Methode de recherche de substances physiologiquement actives, procede de production de ces substances et medicaments decouverts par la methode de recherche
US7855279B2 (en)	2005-09-27	2010-12-21	Amunix Operating, Inc.	Unstructured recombinant polymers and uses thereof
US8703717B2 (en)	2009-02-03	2014-04-22	Amunix Operating Inc.	Growth hormone polypeptides and methods of making and using same
EP3178835B1 (de)	2009-02-03	2019-04-10	Amunix Pharmaceuticals, Inc.	Verlängerte rekombinante polypeptide und zusammensetzungen damit
US8680050B2 (en)	2009-02-03	2014-03-25	Amunix Operating Inc.	Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
US9849188B2 (en)	2009-06-08	2017-12-26	Amunix Operating Inc.	Growth hormone polypeptides and methods of making and using same
JP5976541B2 (ja)	2009-09-17	2016-08-23	シーワイオコーナーイレイドヴィレッジファウンデーション	家畜のジェノタイピング方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5010011A (en) *	1985-03-28	1991-04-23	Wisconsin Alumni Research Foundation	Bovine placental lactogen gene
AU613876B2 (en) *	1986-10-01	1991-08-15	Merck & Co., Inc.	Synthetic genes encoding proteins from plasmid containing eucaryotic secretory signal peptides and process for secreting encoded proteins
GB8718937D0 (en) *	1987-08-11	1987-09-16	Coopers Animal Health	Biologically active molecules
ES2062572T3 (es) *	1989-07-10	1994-12-16	Upjohn Co	Analogos de somatotropina.

1990
- 1990-10-12 AU AU68783/91A patent/AU652545B2/en not_active Expired
- 1990-10-12 DK DK90917592T patent/DK0556171T3/da active
- 1990-10-12 JP JP50038791A patent/JP3789928B2/ja not_active Expired - Lifetime
- 1990-10-12 AT AT90917592T patent/ATE195339T1/de not_active IP Right Cessation
- 1990-10-12 EP EP90917592A patent/EP0556171B1/de not_active Expired - Lifetime
- 1990-10-12 CA CA002067136A patent/CA2067136C/en not_active Expired - Lifetime
- 1990-10-12 DE DE69033603T patent/DE69033603T2/de not_active Expired - Lifetime
- 1990-10-12 WO PCT/US1990/005874 patent/WO1991005853A1/en active IP Right Grant
- 1990-10-12 ES ES90917592T patent/ES2150901T3/es not_active Expired - Lifetime
2000
- 2000-11-02 GR GR20000402431T patent/GR3034743T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0556171A1 (de)	1993-08-25
WO1991005853A1 (en)	1991-05-02
CA2067136A1 (en)	1991-04-13
GR3034743T3 (en)	2001-02-28
AU6878391A (en)	1991-05-16
JPH05505518A (ja)	1993-08-19
JP3789928B2 (ja)	2006-06-28
EP0556171A4 (de)	1992-06-15
ATE195339T1 (de)	2000-08-15
AU652545B2 (en)	1994-09-01
DE69033603T2 (de)	2001-04-12
CA2067136C (en)	2003-07-29
DK0556171T3 (da)	2000-12-18
EP0556171B1 (de)	2000-08-09
ES2150901T3 (es)	2000-12-16

Publication	Publication Date	Title
ATE195339T1 (de)	2000-08-15	Antagonisten von wachstumshormonen
NZ227788A (en)	1991-10-25	Peptide having growth hormone regulatory effects, and compositions
IT9048315A0 (it)	1990-09-27	Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi.
ATE82273T1 (de)	1992-11-15	Leucotrien-antagonisten.
FI921291L (fi)	1992-03-25	Human c3b/c4b-receptor (cri).
ATE115148T1 (de)	1994-12-15	Gereinigtes follikel-stimulierendes hormon.
DE59101613D1 (de)	1994-06-16	Knochennagel zur Versorgung von Oberarmfrakturen.
NO880518L (no)	1988-08-08	Dentalsementmateriale.
DE68908166D1 (de)	1993-09-09	Zuechtung von halbleiterkristall-materialien.
ES2023253B3 (es)	1992-01-01	Composiciones cementosas.
NO852568L (no)	1985-12-30	Fiskeveksthormon-polypeptid.
DK57289D0 (da)	1989-02-08	Dyreprotein
DE3889533D1 (de)	1994-06-16	Giesspunkterniedrigende methacrylatadditive und -zusammensetzungen.
NL192456B (nl)	1997-04-01	Humane eiwitten.
CA2102129A1 (en)	1992-11-02	Growth hormone antagonists
DE69133390D1 (de)	2004-07-01	Verwendung von angiotensin-ii-rezeptorantagonisten in der behandlung von hämorragischem schlaganfall
DE3881533D1 (de)	1993-07-15	Tiermedizinische zusammensetzung zur verhinderung von diarrhoe bei tieren.
DE69106407D1 (de)	1995-02-16	Verfahren zur Herstellung von rekombinantem menschlichem gamma-Interferon ohne Cystein und ohne Methionin am N-Terminal.
DE3886517D1 (de)	1994-02-03	Menschlicher Prourokinase ähnliches Polypeptid.
DE3880520D1 (de)	1993-06-03	Rekombinantes plasmid fuer die expression von l-phenylalanin-ammonialyase und transformierte staemme, die es enthalten.
DE69012206D1 (de)	1994-10-13	Futterpräparate zur Aufzucht von Fischen.
DE3875030D1 (de)	1992-11-05	Leukotrien-antagonisten.
FI884255A0 (fi)	1988-09-15	L-aspartyl-3-(bicykloalkyl)-l -alaninalkylestrar med hoeg soethetsgrad.
NO894179L (no)	1991-04-22	Fiskevandringsanlegg.
DE60138885D1 (de)	2009-07-16	Polypeptide mit aktivität der stimulierung von neutrophilen

Legal Events

Date	Code	Title	Description
2001-08-30	8364	No opposition during term of opposition