DE69029693D1 - Hydantoin- oder Imidazolidintrionderivate zur Vorbeugung oder Behandlung von Niereninsuffizienz - Google Patents
Hydantoin- oder Imidazolidintrionderivate zur Vorbeugung oder Behandlung von NiereninsuffizienzInfo
- Publication number
- DE69029693D1 DE69029693D1 DE69029693T DE69029693T DE69029693D1 DE 69029693 D1 DE69029693 D1 DE 69029693D1 DE 69029693 T DE69029693 T DE 69029693T DE 69029693 T DE69029693 T DE 69029693T DE 69029693 D1 DE69029693 D1 DE 69029693D1
- Authority
- DE
- Germany
- Prior art keywords
- renal failure
- hydantoin
- imidazolidintrione
- prevention
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 208000001647 Renal Insufficiency Diseases 0.000 title abstract 2
- 201000006370 kidney failure Diseases 0.000 title abstract 2
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 title 1
- 229940091173 hydantoin Drugs 0.000 title 1
- ZFLIKDUSUDBGCD-UHFFFAOYSA-N parabanic acid Chemical class O=C1NC(=O)C(=O)N1 ZFLIKDUSUDBGCD-UHFFFAOYSA-N 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001469 hydantoins Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1207699A JP2678499B2 (ja) | 1989-08-09 | 1989-08-09 | 尿毒症毒素低下剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69029693D1 true DE69029693D1 (de) | 1997-02-27 |
DE69029693T2 DE69029693T2 (de) | 1997-05-07 |
Family
ID=16544105
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69029693T Expired - Fee Related DE69029693T2 (de) | 1989-08-09 | 1990-08-07 | Hydantoin- oder Imidazolidintrionderivate zur Vorbeugung oder Behandlung von Niereninsuffizienz |
Country Status (8)
Country | Link |
---|---|
US (1) | US5084473A (de) |
EP (1) | EP0412940B1 (de) |
JP (1) | JP2678499B2 (de) |
KR (1) | KR0151389B1 (de) |
AT (1) | ATE147625T1 (de) |
DE (1) | DE69029693T2 (de) |
DK (1) | DK0412940T3 (de) |
ES (1) | ES2095870T3 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2678499B2 (ja) * | 1989-08-09 | 1997-11-17 | 日本臓器製薬 株式会社 | 尿毒症毒素低下剤 |
US5912261A (en) * | 1994-12-20 | 1999-06-15 | Nippon Zoki Pharmaceutical Co., Ltd. | Carboxyalkyl heterocyclic derivatives |
US6197806B1 (en) * | 1995-12-20 | 2001-03-06 | Nippon Zoki Pharmaceutical Co., Ltd. | Eliminating agent for activated oxygen and free radicals |
JPH10182460A (ja) * | 1996-12-27 | 1998-07-07 | Nippon Zoki Pharmaceut Co Ltd | 3−デオキシグルコソン生成阻害剤 |
AU754989B2 (en) * | 1998-11-16 | 2002-11-28 | Nippon Zoki Pharmaceutical Co., Ltd. | A therapeutic agent for intractable vasculitis |
JP4711523B2 (ja) | 2001-02-13 | 2011-06-29 | 日本臓器製薬株式会社 | 低アルブミン血症改善剤 |
TWI353979B (en) * | 2002-04-10 | 2011-12-11 | Nippon Zoki Pharmaceutical Co | Novel crystal form of 5-hydroxy-1-methylhydantoin |
JP2004123736A (ja) * | 2002-09-11 | 2004-04-22 | Nippon Zoki Pharmaceut Co Ltd | 光学活性(r)−ヒダントイン誘導体 |
JP2004123735A (ja) * | 2002-09-11 | 2004-04-22 | Nippon Zoki Pharmaceut Co Ltd | 光学活性(s)−ヒダントイン誘導体 |
US20060241163A1 (en) * | 2005-04-20 | 2006-10-26 | Kaoru Okamoto | Optically active (S)-hydantoin derivative |
US20060241162A1 (en) * | 2005-04-20 | 2006-10-26 | Kaoru Okamoto | Optically active (R)-hydantoin derivative |
EP1961888A1 (de) * | 2005-12-13 | 2008-08-27 | Osamu Ito | Kombinierte markisenvorrichtung und aufnahmerolle für leinwandflächengebilde |
JP4660616B2 (ja) * | 2009-08-31 | 2011-03-30 | 株式会社東芝 | 基板検査装置 |
JP6509729B2 (ja) * | 2014-02-26 | 2019-05-08 | 日本臓器製薬株式会社 | 慢性腎臓病の進行抑制又は改善剤 |
US11464762B2 (en) | 2017-06-13 | 2022-10-11 | National Cancer Center | Carcinogenesis inhibitor |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
JPS59199652A (ja) * | 1983-04-27 | 1984-11-12 | Kyowa Hakko Kogyo Co Ltd | α−ケトカルボン酸塩類の製造方法 |
JPH0686436B2 (ja) * | 1984-11-15 | 1994-11-02 | 日本臓器製薬株式会社 | 新規ヒダントイン誘導体及び該化合物を含有する医薬組成物 |
AU578068B2 (en) * | 1984-03-08 | 1988-10-13 | Nippon Zoki Pharmaceutical Co., Ltd. | Hydantoin derivatives and pharmaceutical compositions containing them |
JPH062748B2 (ja) * | 1984-03-08 | 1994-01-12 | 日本臓器製薬株式会社 | 新規ヒダントイン誘導体及び該化合物を有効成分として含有する医薬組成物 |
JPH0764729B2 (ja) * | 1985-02-06 | 1995-07-12 | 日本臓器製薬株式会社 | イミダゾリジントリオン誘導体を含有する医薬組成物 |
ATE50248T1 (de) * | 1985-02-06 | 1990-02-15 | Nippon Zoki Pharmaceutical Co | Ein imidazolidintrion-derivat oder ein seiner pharmazeutisch akzeptierbaren salze enthaltende pharmazeutische zusammenstellung. |
JPH0623102B2 (ja) * | 1985-08-22 | 1994-03-30 | 日本臓器製薬株式会社 | 脂質低下剤 |
US4853401A (en) * | 1987-04-01 | 1989-08-01 | G. D. Searle & Co. | Spiro-hydantoins as aldose reductase inhibitors |
JP2678499B2 (ja) * | 1989-08-09 | 1997-11-17 | 日本臓器製薬 株式会社 | 尿毒症毒素低下剤 |
-
1989
- 1989-08-09 JP JP1207699A patent/JP2678499B2/ja not_active Expired - Fee Related
-
1990
- 1990-08-07 ES ES90810592T patent/ES2095870T3/es not_active Expired - Lifetime
- 1990-08-07 DE DE69029693T patent/DE69029693T2/de not_active Expired - Fee Related
- 1990-08-07 DK DK90810592.7T patent/DK0412940T3/da active
- 1990-08-07 AT AT90810592T patent/ATE147625T1/de not_active IP Right Cessation
- 1990-08-07 EP EP90810592A patent/EP0412940B1/de not_active Expired - Lifetime
- 1990-08-09 KR KR1019900012231A patent/KR0151389B1/ko not_active IP Right Cessation
- 1990-08-09 US US07/564,520 patent/US5084473A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0412940A2 (de) | 1991-02-13 |
DE69029693T2 (de) | 1997-05-07 |
EP0412940A3 (en) | 1991-10-23 |
US5084473A (en) | 1992-01-28 |
JPH0372463A (ja) | 1991-03-27 |
KR910004191A (ko) | 1991-03-28 |
EP0412940B1 (de) | 1997-01-15 |
JP2678499B2 (ja) | 1997-11-17 |
DK0412940T3 (da) | 1997-07-14 |
ATE147625T1 (de) | 1997-02-15 |
ES2095870T3 (es) | 1997-03-01 |
KR0151389B1 (ko) | 1998-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |