[go: up one dir, main page]

DE69022578D1 - Test für Hepatitis-C. - Google Patents

Test für Hepatitis-C.

Info

Publication number
DE69022578D1
DE69022578D1 DE69022578T DE69022578T DE69022578D1 DE 69022578 D1 DE69022578 D1 DE 69022578D1 DE 69022578 T DE69022578 T DE 69022578T DE 69022578 T DE69022578 T DE 69022578T DE 69022578 D1 DE69022578 D1 DE 69022578D1
Authority
DE
Germany
Prior art keywords
assay
sample
hepatitis
test
hcv antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69022578T
Other languages
English (en)
Other versions
DE69022578T2 (de
Inventor
Tat Leung
James M Casey
Virender Kumar Sarin
Smriti U Mehta
Sushil G Devare
Richard R Lesniewski
Suresh M Desai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69022578D1 publication Critical patent/DE69022578D1/de
Publication of DE69022578T2 publication Critical patent/DE69022578T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE69022578T 1989-12-22 1990-12-22 Test für Hepatitis-C. Expired - Fee Related DE69022578T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45616289A 1989-12-22 1989-12-22
US61018090A 1990-11-07 1990-11-07

Publications (2)

Publication Number Publication Date
DE69022578D1 true DE69022578D1 (de) 1995-10-26
DE69022578T2 DE69022578T2 (de) 1996-05-02

Family

ID=27038137

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69022578T Expired - Fee Related DE69022578T2 (de) 1989-12-22 1990-12-22 Test für Hepatitis-C.

Country Status (7)

Country Link
EP (1) EP0445423B1 (de)
JP (1) JP3188717B2 (de)
AT (1) ATE128237T1 (de)
AU (1) AU638304B2 (de)
CA (1) CA2032907C (de)
DE (1) DE69022578T2 (de)
ES (1) ES2080099T3 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
JP2656996B2 (ja) * 1989-05-18 1997-09-24 カイロン コーポレイション Ｎａｎｂｖの診断用薬
US5308750A (en) * 1989-12-22 1994-05-03 Abbott Laboratories Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
BR9106309A (pt) † 1990-04-04 1993-04-20 Chiron Corp Combinacao de antigenos sinteticos de hepatite c viral (hcv),processo de detectar anticorpos para o virus da hepatite c e estojo para realizar teste
AU660925B2 (en) * 1990-04-06 1995-07-13 Genelabs Technologies, Inc. Hepatitis C virus epitopes
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
ATE206717T1 (de) * 1990-11-03 2001-10-15 Dade Behring Marburg Gmbh Hcv-spezifische peptide, mittel dazu und ihre verwendung
EP0485209A1 (de) * 1990-11-08 1992-05-13 Immuno Japan Inc. Mit Non-A Non-B Hepatitis Virus verwandtes Antigen, Aufspürsysteme für Antikörper, Polynukleotide und Polypeptide
WO1992009634A1 (en) * 1990-11-29 1992-06-11 Toray Industries, Incorporated Non-a non-b hepatitis virus antigen protein
US6007982A (en) * 1990-12-14 1999-12-28 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
US5910404A (en) 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
DK0489968T3 (da) * 1990-12-14 1997-03-24 Innogenetics Nv Syntetiske antigener til påvisning af antistoffer imod hepatitis C virus
AU1459792A (en) * 1991-01-14 1992-08-27 James N. Gamble Institute Of Medical Research Basic structural immunogenic polypeptides having epitopes for hcv, antibodies, polynucleotide sequences, vaccines and methods
WO1992013892A1 (en) * 1991-01-31 1992-08-20 Abbott Laboratories Monoclonal antibodies to putative hcv envelope region and methods for using same
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
RO117329B1 (ro) * 1991-06-24 2002-01-30 Chiron Corp Emeryville Polipeptide care contin o secventa a virusului hepatitei c
EP0599913B1 (de) * 1991-08-21 1998-12-02 Abbott Laboratories Monoklonale antikörper gegen mutmassliche hepatitis c-virus ns5-proteine und ihre anwendungsmethoden
WO1993006247A1 (en) * 1991-09-16 1993-04-01 Abbott Laboratories Hepatitis c assay
AU671967B2 (en) 1991-11-21 1996-09-19 Common Services Agency Hepatitis-C virus testing
JPH05176773A (ja) * 1991-12-27 1993-07-20 Imuno Japan:Kk オリゴヌクレオチド、オリゴペプタイド、ならびに抗ｃ型肝 炎ウイルス抗体検出・鑑別方法
GB9203803D0 (en) * 1992-02-21 1992-04-08 Wellcome Found A recombinant polypeptide
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
GB2294690B (en) * 1994-11-01 1998-10-28 United Biomedical Inc Peptides effective for diagnosis and detection of hepatitis C infection
DE19504302A1 (de) * 1995-02-09 1996-08-14 Boehringer Mannheim Gmbh Methode zur serologischen Typisierung mittels typspezifischer Antigene
DE19540105C1 (de) * 1995-09-19 1997-02-20 United Biomedical Inc Peptidzusammensetzungen zur Diagnose und zum Nachweis von Hepatitis C Virus (HCV)-Infektion
WO1999024466A2 (en) 1997-11-06 1999-05-20 Innogenetics N.V. Multi-mer peptides derived from hepatitis c virus envelope proteins for diagnostic use and vaccination purposes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE318216T1 (de) * 1987-11-18 1990-06-13 Chiron Corp., Emeryville, Calif. Nanbv-diagnostika und vakzine.
UA50829C2 (uk) * 1989-03-17 2002-11-15 Чірон Корпорейшн Очищений поліпептид, що містить антиген вірусу гепатиту с, полінуклеотид, вектор, клітини, система експресії, моноклональне антитіло, препарат поліклональних антитіл, нуклеотидна проба, аналітичні набори, спосіб виявлення нуклеїнових кислот, способи імуноаналізу, вакцина, спосіб одержання антитіл

Also Published As

Publication number Publication date
ES2080099T3 (es) 1996-02-01
DE69022578T2 (de) 1996-05-02
JPH04253998A (ja) 1992-09-09
EP0445423A2 (de) 1991-09-11
CA2032907C (en) 2002-05-14
AU638304B2 (en) 1993-06-24
AU6839090A (en) 1991-06-27
EP0445423B1 (de) 1995-09-20
EP0445423A3 (en) 1992-04-29
CA2032907A1 (en) 1991-06-23
JP3188717B2 (ja) 2001-07-16
ATE128237T1 (de) 1995-10-15

Similar Documents

Publication Publication Date Title
DE69022578D1 (de) Test für Hepatitis-C.
ES2082777T3 (es) Un metodo para la deteccion de un anti-cuerpo y antigeno en un inmunoensayo.
ES2145746T3 (es) Analisis de deteccion de hepatitis c.
ES2148225T3 (es) Reactivos y procedimientos que permiten la deteccion y la cuantificacion de la tiroxina en muestras de fluido.
EP0375422A3 (de) Zusammensetzung und Methoden zur Bestimmung der Anwesenheit von Amphetaminen in einer Probe, die in Verdacht steht, Amphetamine und/oder Metamphetamine zu enthalten
ES2139571T3 (es) Ensayo de hepatitis c que utiliza antigenos recombinantes.
ATE109825T1 (de) Monoklonale antikörper und verfahren zum nachweis von dioxinen und dibenzofuranen.
DE69025940D1 (de) Durch Silber intensiviertes, auf Goldmarkierung beruhendes Immuntestverfahren
ATE254286T1 (de) Zwei-inkubations mit markiertem antigen verwendenes immunoassay
ES2023868B3 (es) Procedimiento de determinacion inmunometrico
DE3579856D1 (de) Immunulogischer test zur bestimmung von gemeinsamen, bestimmenden hepatitis-b-antikoerpern.
EP0245052A3 (de) Feststellung einer Entzündung und Antikörper dazu
ATE67603T1 (de) Zusammensetzungen zum immunoenzymatischen test von prostaglandinen.
ATE182172T1 (de) Immunologischer nachweis von metolachlor
DE3679926D1 (de) Nachweis von human-t-zellen-leukemievirus des typs-iii.
ATE143142T1 (de) Immunoassay zum nachweis von antikörpern gegen hiv
ATE180282T1 (de) Antikörpertest zur erkennung von alkoholikern und zur überwachung der alkoholaufnahme
GR940300091T1 (en) Equipment and test for determining an antigen/antibody in a test sample.
DE60018785D1 (de) Immunoassay von c-peptid-enthaltenden verunreinigungen in rekombinantem human-insulin
ES2016992B3 (es) Reagente y procedimiento en la determinacion c 3a mediante ensayo inmunoquimico.
ES2066973T3 (es) Inmunoanalisis de elastasa-1.
IT1237809B (it) Metodo per la determinazione qualitativa e quantitativa di anticorpi diretti contro antigeni batterici attraverso la misurazione fotometrica dell'agglutinazione.
CA2116026A1 (en) Hepatitis c assay utilizing recombinant antigens to c-100 region
KR910001378A (ko) HIV p24 정량 패널
ATE208041T1 (de) A-protein als diagnostikum für krebs

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee