DE68928080D1 - Einstufiges in situ-hybridierungstestverfahren - Google Patents
Einstufiges in situ-hybridierungstestverfahrenInfo
- Publication number
- DE68928080D1 DE68928080D1 DE68928080T DE68928080T DE68928080D1 DE 68928080 D1 DE68928080 D1 DE 68928080D1 DE 68928080 T DE68928080 T DE 68928080T DE 68928080 T DE68928080 T DE 68928080T DE 68928080 D1 DE68928080 D1 DE 68928080D1
- Authority
- DE
- Germany
- Prior art keywords
- test procedure
- hybrid test
- situ hybrid
- situ
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000010998 test method Methods 0.000 title 1
- 229920001222 biopolymer Polymers 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 238000012296 in situ hybridization assay Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Materials For Medical Uses (AREA)
- Inorganic Insulating Materials (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Television Systems (AREA)
- Stereo-Broadcasting Methods (AREA)
- Valve Device For Special Equipments (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23910688A | 1988-08-31 | 1988-08-31 | |
PCT/US1989/003580 WO1990002173A1 (en) | 1988-08-31 | 1989-08-18 | One-step in situ hybridization assay |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68928080D1 true DE68928080D1 (de) | 1997-07-03 |
DE68928080T2 DE68928080T2 (de) | 1998-01-15 |
Family
ID=22900643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68928080T Expired - Lifetime DE68928080T2 (de) | 1988-08-31 | 1989-08-18 | Einstufiges in situ-hybridierungstestverfahren |
Country Status (12)
Country | Link |
---|---|
EP (2) | EP0432221B1 (de) |
JP (1) | JPH04502552A (de) |
AT (1) | ATE153705T1 (de) |
AU (1) | AU636854B2 (de) |
DE (1) | DE68928080T2 (de) |
DK (1) | DK34191A (de) |
FI (1) | FI910957A7 (de) |
IL (1) | IL91405A (de) |
NZ (1) | NZ230389A (de) |
PT (1) | PT91589B (de) |
WO (1) | WO1990002173A1 (de) |
ZA (1) | ZA896490B (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5985549A (en) * | 1985-10-22 | 1999-11-16 | University Of Massachusetts | Non-isotopic in-situ hybridization method for detection of nucleic acids |
US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
WO1990002173A1 (en) * | 1988-08-31 | 1990-03-08 | Research Development Foundation | One-step in situ hybridization assay |
US6242184B1 (en) | 1988-10-18 | 2001-06-05 | University Of Massachusetts | In-situ hybridization of single-copy and multiple-copy nucleic acid sequences |
US6203977B1 (en) | 1988-11-15 | 2001-03-20 | Yale University | Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization |
EP0462221A1 (de) * | 1989-03-07 | 1991-12-27 | Syngene, Inc. | In situ Hybridisierung in Suspension zum Nachweis und zur Trennung von Zellen |
US5547839A (en) | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
IL99025A0 (en) * | 1990-08-15 | 1992-07-15 | Astra Ab | Novel process for the detection of pathogens using dna probes |
AU4685593A (en) * | 1992-07-17 | 1994-02-14 | Aprogenex, Inc. | Enriching and identyfying fetal cells in maternal blood for in situ hybridization |
US5521061A (en) * | 1992-07-17 | 1996-05-28 | Aprogenex, Inc. | Enhancement of probe signal in nucleic acid-mediated in-situ hybridization studies |
US5629147A (en) * | 1992-07-17 | 1997-05-13 | Aprogenex, Inc. | Enriching and identifying fetal cells in maternal blood for in situ hybridization |
WO1997005282A2 (en) * | 1995-07-28 | 1997-02-13 | Rijksuniversiteit Groningen | Methods and materials for determining relative abundance of microorganisms in mixed populations |
EP0900286A1 (de) * | 1996-04-19 | 1999-03-10 | PHARMACIA & UPJOHN COMPANY | IN SITU mRNA HYBRIDISIERUNGSVERFAHREN IM GROSSEN VOLUMEN ZUR QUANTIFIZIERUNG UND ENTDECKUNG VON KRANKHEITSSPEZIFISCHEN GENEN |
WO1999060163A1 (en) * | 1998-05-18 | 1999-11-25 | Igenex, Inc. | In situ hybridization method for detecting target nucleic acid |
JP4557347B2 (ja) * | 2000-01-30 | 2010-10-06 | 株式会社カイノス | 特定の塩基配列を有する標的核酸の検出またはその核酸量の測定方法 |
US20040115692A1 (en) * | 2000-04-03 | 2004-06-17 | Cytyc Corporation | Methods, compositions and apparatuses for detecting a target in a preservative solution |
US9212390B2 (en) | 2010-04-30 | 2015-12-15 | Exiqon A/S | In situ hybridization method and buffer |
WO2021207062A1 (en) * | 2020-04-07 | 2021-10-14 | Advanced Cell Diagnostics, Inc. | Methods for detecting target nucleic acids by in situ hybridization and a kit thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990002173A1 (en) * | 1988-08-31 | 1990-03-08 | Research Development Foundation | One-step in situ hybridization assay |
EP0462221A1 (de) * | 1989-03-07 | 1991-12-27 | Syngene, Inc. | In situ Hybridisierung in Suspension zum Nachweis und zur Trennung von Zellen |
-
1989
- 1989-08-18 WO PCT/US1989/003580 patent/WO1990002173A1/en active IP Right Grant
- 1989-08-18 FI FI910957A patent/FI910957A7/fi not_active Application Discontinuation
- 1989-08-18 AU AU43439/89A patent/AU636854B2/en not_active Ceased
- 1989-08-18 JP JP1510636A patent/JPH04502552A/ja active Pending
- 1989-08-18 DE DE68928080T patent/DE68928080T2/de not_active Expired - Lifetime
- 1989-08-18 AT AT89911504T patent/ATE153705T1/de not_active IP Right Cessation
- 1989-08-18 EP EP89911504A patent/EP0432221B1/de not_active Expired - Lifetime
- 1989-08-22 NZ NZ230389A patent/NZ230389A/xx unknown
- 1989-08-24 IL IL9140589A patent/IL91405A/en not_active IP Right Cessation
- 1989-08-25 ZA ZA896490A patent/ZA896490B/xx unknown
- 1989-08-30 PT PT91589A patent/PT91589B/pt not_active IP Right Cessation
- 1989-08-31 EP EP19890308850 patent/EP0357436A3/de not_active Withdrawn
-
1991
- 1991-02-27 DK DK034191A patent/DK34191A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ATE153705T1 (de) | 1997-06-15 |
DK34191A (da) | 1991-04-30 |
IL91405A0 (en) | 1990-04-29 |
DK34191D0 (da) | 1991-02-27 |
FI910957A0 (fi) | 1991-02-27 |
IL91405A (en) | 1996-03-31 |
EP0432221A1 (de) | 1991-06-19 |
EP0432221A4 (en) | 1992-01-15 |
PT91589B (pt) | 1995-08-09 |
JPH04502552A (ja) | 1992-05-14 |
NZ230389A (en) | 1991-11-26 |
ZA896490B (en) | 1990-06-27 |
EP0357436A2 (de) | 1990-03-07 |
EP0357436A3 (de) | 1991-06-12 |
PT91589A (pt) | 1990-03-08 |
DE68928080T2 (de) | 1998-01-15 |
FI910957A7 (fi) | 1991-02-27 |
AU4343989A (en) | 1990-03-23 |
EP0432221B1 (de) | 1997-05-28 |
AU636854B2 (en) | 1993-05-13 |
WO1990002173A1 (en) | 1990-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |