DE68926548D1 - Verfahren zur enzymatischen Herstellung von beta-Lactamen - Google Patents

Verfahren zur enzymatischen Herstellung von beta-Lactamen

Info

Publication number: DE68926548D1
Authority: DE; Germany
Prior art keywords: beta; lactams; enzymatic production; enzymatic; aminophenylacetamido
Prior art date: 1988-04-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE68926548T

Other languages

English (en)

Other versions

DE68926548T2 (de

Inventor

Der Laken Cornelis Jacobus Van

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

DSM IP Assets BV

Original Assignee

Gist Brocades NV

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-26

Filing date

1989-04-25

Publication date

1996-07-04

1989-04-25 Application filed by Gist Brocades NV filed Critical Gist Brocades NV

1996-07-04 Publication of DE68926548D1 publication Critical patent/DE68926548D1/de

1996-09-26 Application granted granted Critical

1996-09-26 Publication of DE68926548T2 publication Critical patent/DE68926548T2/de

2009-04-26 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
- C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DE68926548T 1988-04-26 1989-04-25 Verfahren zur enzymatischen Herstellung von beta-Lactamen Expired - Fee Related DE68926548T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP88200811		1988-04-26

Publications (2)

Publication Number	Publication Date
DE68926548D1 true DE68926548D1 (de)	1996-07-04
DE68926548T2 DE68926548T2 (de)	1996-09-26

Family

ID=8199787

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE68926548T Expired - Fee Related DE68926548T2 (de)	1988-04-26	1989-04-25	Verfahren zur enzymatischen Herstellung von beta-Lactamen

Country Status (9)

Country	Link
EP (1)	EP0339751B1 (de)
JP (1)	JP2771244B2 (de)
KR (1)	KR890016184A (de)
AT (1)	ATE138690T1 (de)
DE (1)	DE68926548T2 (de)
DK (1)	DK198789A (de)
ES (1)	ES2090031T3 (de)
GR (1)	GR3020486T3 (de)
PT (1)	PT90373B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2086250C (en) *	1990-07-04	2001-05-29	Svend Gunnar Kaasgaard	Process for preparation of beta-lactams
WO1993012250A1 (en) *	1991-12-19	1993-06-24	Novo Nordisk A/S	AN IMPROVED METHOD FOR THE PREPARATION OF CERTAIN β-LACTAM ANTIBIOTICS
EP0734452A1 (de) *	1994-06-10	1996-10-02	Gist-Brocades B.V.	Verbessertes acylierungsverfahren für penicillinen und cephalosporinen
CN1095875C (zh) *	1994-07-18	2002-12-11	吉斯特·布罗卡迪斯股份有限公司	在恒定的高反应物浓度下制备β－内酰胺的方法
US6320069B1 (en)	1996-07-02	2001-11-20	Toray Industries, Inc.	Production of optically active ketone
BR9804858A (pt) *	1997-04-22	1999-08-24	Gist Brocades Bv	M-todo de prepara-Æo de antibiÄtico b-lactam
SMT201800111T1 (it)	2010-09-07	2018-05-02	Dsm Sinochem Pharm Nl Bv	Processo per la produzione di cefalosporine
EP2723881A2 (de)	2011-06-23	2014-04-30	DSM Sinochem Pharmaceuticals Netherlands B.V.	Neues kristallines cefoperazon-zwischenprodukt
US20140200342A1 (en)	2011-06-23	2014-07-17	Dsm Sinochem Pharmaceuticals Netherlands B.V.	Process for preparing 3'-thiosubstituted cephalosporins employing a pencillin g acylase

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5343597B1 (de) *	1970-12-25	1978-11-21
JPS5548797B1 (de) *	1971-04-02	1980-12-08
US3904606A (en) *	1973-01-12	1975-09-09	Upjohn Co	Process for preparing optically active 6-(' -amino-acetamido)penicillanic acids and 7-(' -aminoacetamido) cephalosporanic acids
JPS51133488A (en) *	1975-05-14	1976-11-19	Shionogi & Co Ltd	Process for producing antibiotics enzymatically
JPS591995Y2 (ja) *	1980-02-21	1984-01-19	日立造船株式会社	微細粒を含有する液体の貯溜槽
JPS63294933A (ja) *	1987-05-27	1988-12-01	Niigata Eng Co Ltd	スラリ−貯槽
JPS63294932A (ja) *	1987-05-27	1988-12-01	Niigata Eng Co Ltd	スラリーの貯蔵装置

1989
- 1989-04-25 ES ES89201074T patent/ES2090031T3/es not_active Expired - Lifetime
- 1989-04-25 DE DE68926548T patent/DE68926548T2/de not_active Expired - Fee Related
- 1989-04-25 DK DK198789A patent/DK198789A/da not_active Application Discontinuation
- 1989-04-25 EP EP89201074A patent/EP0339751B1/de not_active Expired - Lifetime
- 1989-04-25 AT AT89201074T patent/ATE138690T1/de not_active IP Right Cessation
- 1989-04-26 KR KR1019890005508A patent/KR890016184A/ko not_active Application Discontinuation
- 1989-04-26 JP JP1107111A patent/JP2771244B2/ja not_active Expired - Fee Related
- 1989-04-26 PT PT90373A patent/PT90373B/pt not_active IP Right Cessation
1996
- 1996-07-09 GR GR960401854T patent/GR3020486T3/el unknown

Also Published As

Publication number	Publication date
ATE138690T1 (de)	1996-06-15
KR890016184A (ko)	1989-11-28
JPH01312998A (ja)	1989-12-18
PT90373B (pt)	1994-09-30
GR3020486T3 (en)	1996-10-31
JP2771244B2 (ja)	1998-07-02
EP0339751A1 (de)	1989-11-02
DK198789D0 (da)	1989-04-25
PT90373A (pt)	1989-11-10
EP0339751B1 (de)	1996-05-29
DE68926548T2 (de)	1996-09-26
DK198789A (da)	1989-10-27
ES2090031T3 (es)	1996-10-16

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Legal Events

Date	Code	Title	Description
1997-06-26	8364	No opposition during term of opposition
1999-07-01	8327	Change in the person/name/address of the patent owner	Owner name: DSM N.V., HEERLEN, NL
2004-05-13	8327	Change in the person/name/address of the patent owner	Owner name: DSM IP ASSETS B.V., HEERLEN, NL
2006-02-09	8339	Ceased/non-payment of the annual fee