[go: up one dir, main page]

DE68917709D1 - Verfahren zur Herstellung eines Pertussis-Toxin-Toxoides. - Google Patents

Verfahren zur Herstellung eines Pertussis-Toxin-Toxoides.

Info

Publication number
DE68917709D1
DE68917709D1 DE68917709T DE68917709T DE68917709D1 DE 68917709 D1 DE68917709 D1 DE 68917709D1 DE 68917709 T DE68917709 T DE 68917709T DE 68917709 T DE68917709 T DE 68917709T DE 68917709 D1 DE68917709 D1 DE 68917709D1
Authority
DE
Germany
Prior art keywords
pertussis toxin
toxoid
preparation
toxin toxoid
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68917709T
Other languages
English (en)
Other versions
DE68917709T2 (de
Inventor
Akihiro Ginnaga
Kazunori Morokuma
Katsutoshi Aihara
Mitsuo Sakoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Application granted granted Critical
Publication of DE68917709D1 publication Critical patent/DE68917709D1/de
Publication of DE68917709T2 publication Critical patent/DE68917709T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE68917709T 1988-11-29 1989-11-29 Verfahren zur Herstellung eines Pertussis-Toxin-Toxoides. Expired - Lifetime DE68917709T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63303767A JP2706792B2 (ja) 1988-11-29 1988-11-29 百日咳毒素のトキソイド化法

Publications (2)

Publication Number Publication Date
DE68917709D1 true DE68917709D1 (de) 1994-09-29
DE68917709T2 DE68917709T2 (de) 1995-05-04

Family

ID=17925036

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68917709T Expired - Lifetime DE68917709T2 (de) 1988-11-29 1989-11-29 Verfahren zur Herstellung eines Pertussis-Toxin-Toxoides.

Country Status (6)

Country Link
US (1) US4996299A (de)
EP (1) EP0377114B1 (de)
JP (1) JP2706792B2 (de)
AT (1) ATE110279T1 (de)
CA (1) CA2004206C (de)
DE (1) DE68917709T2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5165927A (en) * 1986-08-01 1992-11-24 University Of Southern California Composition with modified pertussis toxin
US5332583A (en) * 1987-11-24 1994-07-26 Connaught Laboratories Limited Vaccine containing genetically-detoxified pertussis holotoxin
US5578308A (en) * 1990-02-12 1996-11-26 Capiau; Carine Glutaraldehyde and formalin detoxified bordetella toxin vaccine
GB9021004D0 (en) * 1990-09-27 1990-11-07 Wellcome Found Acellular vaccines
GB9216351D0 (en) * 1992-07-31 1992-09-16 Wellcome Found Vaccine production
BRPI0402630B8 (pt) * 2004-07-05 2021-05-25 Fund Butantan processo de obtenção de vacina pertussis celular menos reatogênica
JP5207380B2 (ja) * 2006-03-27 2013-06-12 北里第一三共ワクチン株式会社 長期保存においても毒性復帰がおこらない特徴を持つ全菌体細菌ワクチンならびにその用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5750925A (en) * 1980-09-12 1982-03-25 Takeda Chem Ind Ltd Preparation of pertussis toxoid
CA1213234A (en) * 1983-03-30 1986-10-28 Akihiro Ginnaga Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine
KR890001003B1 (ko) * 1984-07-19 1989-04-18 자이단 호오진 까가꾸 오요비 겟세이 료오호 겐뀨쇼 Lpf-ha의 정제방법
GB8512972D0 (en) * 1985-05-22 1985-06-26 Univ Glasgow Vaccine production
GB8601279D0 (en) * 1986-01-20 1986-02-26 Public Health Lab Service Purification of pertussis antigens
FR2597344B1 (fr) * 1986-04-16 1989-06-23 Merieux Inst Perfectionnement au procede de purification d'antigenes proteiques de bacteries appartenant au genre bordetella, en vue de l'obtention d'un vaccin acellulaire.
US4762710A (en) * 1986-06-16 1988-08-09 The United States Of America As Represented By The Department Of Health And Human Services Novel method of preparing toxoid by oxidation and metal ions
US4845036A (en) * 1987-02-03 1989-07-04 The United States Of America As Represented By The Department Of Health And Human Services Process for isolation of the B oligomer of pertussis toxin
CA1337859C (en) * 1987-04-24 1996-01-02 Masashi Chazono Method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine

Also Published As

Publication number Publication date
JPH02149529A (ja) 1990-06-08
CA2004206C (en) 2000-02-08
ATE110279T1 (de) 1994-09-15
CA2004206A1 (en) 1990-05-29
DE68917709T2 (de) 1995-05-04
US4996299A (en) 1991-02-26
EP0377114B1 (de) 1994-08-24
JP2706792B2 (ja) 1998-01-28
EP0377114A1 (de) 1990-07-11

Similar Documents

Publication Publication Date Title
DE69022454D1 (de) Verfahren zur Herstellung eines Polyborosilazanes.
DE69015226D1 (de) Verfahren zur Herstellung eines Fluororganopolysiloxans.
DE69011859D1 (de) Verwendung von sigma-rezeptor-liganden zur herstellung eines anxiolytikums.
NO165478C (no) Fremgangsmaate for fremstilling av antigeniske preparater.
DE68918016D1 (de) Verfahren zur Herstellung eines Dimethyltetralins.
DE3785157D1 (de) Verfahren zur herstellung von toxoid.
ATE116541T1 (de) Verfahren zur herstellung mikronisierter bioabbaubarer partikel.
DE69016848D1 (de) Verfahren zur Herstellung eines Hohlkörpers.
DE68917709D1 (de) Verfahren zur Herstellung eines Pertussis-Toxin-Toxoides.
DE69034264D1 (de) Verfahren zur Herstellung eines azellulären Impfstoffes der Bordetella pertussis Antigene enthält
DE69427955D1 (de) Verfahren zur Herstellung von 2,2-Difluorketensilylacetalen und alpha,alpha-Difluor-beta -Silyloxy-1,3-Dioxolan-4-Propansäureestern
DE59004655D1 (de) Verfahren zur Herstellung eines poly-1-olefins.
EP0202947A3 (de) Impfstoffproduktion
DE68924453D1 (de) Verfahren zur Herstellung eines Polyisocyanats.
CY1935A (en) Novel vaccine and method therefor
ATE218131T1 (de) Verfahren zur herstellung von mono-n- substituierten tetraazamakrocyclen
DE59105327D1 (de) Verfahren zur Herstellung eines Feuchthaltemittels.
DE69019199D1 (de) Verfahren zur Herstellung eines Fluororganopolysiloxans.
DE69017570D1 (de) Verfahren zur Herstellung eines Lactons.
YU80389A (en) Process for obtaining pertusis toxoide
ATE99925T1 (de) Verfahren zur herstellung eines ranitidin-harzabsorbates.
ATE187252T1 (de) Verfahren zur herstellung langzeitstabiler klarer seren
ATE63061T1 (de) Verfahren zur herstellung eines stabilen nicorandilpraeparats.
DK49685A (da) Fremgangsmaade til fremstilling af en modificeret levende pasteurella haemolytica vaccine

Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition