DE60334289D1 - Dithiolopyrrolon-derivate zur behandlung von proliferativen störungen - Google Patents
Dithiolopyrrolon-derivate zur behandlung von proliferativen störungenInfo
- Publication number
- DE60334289D1 DE60334289D1 DE60334289T DE60334289T DE60334289D1 DE 60334289 D1 DE60334289 D1 DE 60334289D1 DE 60334289 T DE60334289 T DE 60334289T DE 60334289 T DE60334289 T DE 60334289T DE 60334289 D1 DE60334289 D1 DE 60334289D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- proliferative disorder
- dithiolopyrrolone
- dithiolopyrrolone derivatives
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36726502P | 2002-03-26 | 2002-03-26 | |
| US41869802P | 2002-10-17 | 2002-10-17 | |
| PCT/CA2003/000380 WO2003080624A2 (en) | 2002-03-26 | 2003-03-18 | Dithiolopyrrolone derivatives useful in the treatment of proliferative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60334289D1 true DE60334289D1 (de) | 2010-11-04 |
Family
ID=28457151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60334289T Expired - Lifetime DE60334289D1 (de) | 2002-03-26 | 2003-03-18 | Dithiolopyrrolon-derivate zur behandlung von proliferativen störungen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9051330B2 (de) |
| EP (1) | EP1490374B1 (de) |
| JP (1) | JP4530667B2 (de) |
| KR (1) | KR100839214B1 (de) |
| CN (1) | CN100347176C (de) |
| AT (1) | ATE482217T1 (de) |
| CA (1) | CA2479341C (de) |
| DE (1) | DE60334289D1 (de) |
| HK (1) | HK1074840A1 (de) |
| WO (1) | WO2003080624A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2433417C (en) | 2001-01-18 | 2010-10-19 | Welichem Biotech Inc. | Novel 1,2-diphenylethene derivatives for treatment of immune diseases |
| WO2008038175A2 (en) * | 2006-09-29 | 2008-04-03 | Celestial Pharmaceuticals (Shenzhen) Ltd. | Dithiolopyrrolones compounds and their therapeutic applications |
| CN101381371B (zh) * | 2007-09-05 | 2011-05-18 | 上海医药工业研究院 | 二硫杂环戊烯并吡咯酮类化合物及其制备方法和应用 |
| CN102219724B (zh) * | 2010-05-17 | 2014-10-01 | 上海现代制药股份有限公司 | 吡咯酮类化合物及其制备方法和应用 |
| CN102432624B (zh) * | 2011-08-26 | 2013-12-18 | 魏爽 | 一种二硫杂环戊烯并吡咯酮类化合物结晶的制备工艺 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2752359A (en) * | 1952-10-06 | 1956-06-26 | Pfizer & Co C | Antimicrobial agents |
| US2798811A (en) * | 1953-07-23 | 1957-07-09 | Schaefer Brewing Co | Inhibiting micro-biological growth in beer |
| US2776967A (en) * | 1955-09-08 | 1957-01-08 | Upjohn Co | Diketopregnanespirothiazolidine |
| US3038819A (en) * | 1958-08-25 | 1962-06-12 | Sidney H Ross | Antibiotics as preservatives for industrial materials |
| US3057779A (en) * | 1960-03-14 | 1962-10-09 | American Cyanamid Co | Antibiotic and production thereof |
| GB2170498A (en) | 1985-02-04 | 1986-08-06 | Ici Plc | Processes for making fungicidal dithiolopyrrolones |
| GB2173499A (en) | 1985-02-04 | 1986-10-15 | Ici Plc | Fungicidal dithiolopyrrolones |
| JPS63112586A (ja) * | 1986-10-29 | 1988-05-17 | Nippon Kayaku Co Ltd | ３−アシルアミノ−４−オキソ−４，５−ジヒドロ−１，２−ジチオロ〔４，３−ｂ〕ピロ−ル誘導体の製法 |
| GB9310485D0 (en) | 1993-05-21 | 1993-07-07 | Smithkline Beecham Plc | Novel compounds |
| EP0712405A1 (de) | 1993-08-13 | 1996-05-22 | Smithkline Beecham Plc | Derivate der monsäuren a und c mit antibakterieller, antimycloplasmatischer, fungizider und herbizider aktivität |
| US6583171B1 (en) * | 1996-04-04 | 2003-06-24 | Welichem Biotech Inc. | Antineoplastic agents |
| US5827872A (en) * | 1996-08-23 | 1998-10-27 | Webster; John M. | Xenomins novel heterocyclic compounds with antimicrobial and antneoplastic properties |
| US6020360A (en) * | 1996-09-18 | 2000-02-01 | Webster; John M. | Anticancer property of dithiolopyrrolones |
| CA2212237A1 (en) * | 1997-09-05 | 1999-03-05 | John M. Webster | Novel antineoplastic agents |
| JP4960548B2 (ja) * | 2000-01-07 | 2012-06-27 | セケラ インコーポレイテッド | 新規抗細菌化合物の用途 |
| WO2008038175A2 (en) * | 2006-09-29 | 2008-04-03 | Celestial Pharmaceuticals (Shenzhen) Ltd. | Dithiolopyrrolones compounds and their therapeutic applications |
-
2003
- 2003-03-18 AT AT03744744T patent/ATE482217T1/de not_active IP Right Cessation
- 2003-03-18 JP JP2003578378A patent/JP4530667B2/ja not_active Expired - Fee Related
- 2003-03-18 US US10/509,074 patent/US9051330B2/en not_active Expired - Fee Related
- 2003-03-18 CN CNB038068826A patent/CN100347176C/zh not_active Expired - Lifetime
- 2003-03-18 EP EP03744744A patent/EP1490374B1/de not_active Expired - Lifetime
- 2003-03-18 WO PCT/CA2003/000380 patent/WO2003080624A2/en active Application Filing
- 2003-03-18 KR KR1020047015537A patent/KR100839214B1/ko not_active Expired - Fee Related
- 2003-03-18 DE DE60334289T patent/DE60334289D1/de not_active Expired - Lifetime
- 2003-03-18 CA CA2479341A patent/CA2479341C/en not_active Expired - Fee Related
-
2005
- 2005-08-19 HK HK05107222A patent/HK1074840A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1490374B1 (de) | 2010-09-22 |
| KR20050008666A (ko) | 2005-01-21 |
| US20060074125A1 (en) | 2006-04-06 |
| CA2479341A1 (en) | 2003-10-02 |
| CN100347176C (zh) | 2007-11-07 |
| WO2003080624A2 (en) | 2003-10-02 |
| US9051330B2 (en) | 2015-06-09 |
| HK1074840A1 (en) | 2005-11-25 |
| AU2003209899A1 (en) | 2003-10-08 |
| KR100839214B1 (ko) | 2008-06-17 |
| WO2003080624A3 (en) | 2004-03-25 |
| JP2005526803A (ja) | 2005-09-08 |
| CA2479341C (en) | 2012-07-10 |
| EP1490374A2 (de) | 2004-12-29 |
| CN1642959A (zh) | 2005-07-20 |
| JP4530667B2 (ja) | 2010-08-25 |
| AU2003209899B2 (en) | 2009-07-09 |
| ATE482217T1 (de) | 2010-10-15 |
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