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DE60331638D1 - Keratin-netzwerke enthaltende wundverbände für gewebedefekte - Google Patents

Keratin-netzwerke enthaltende wundverbände für gewebedefekte

Info

Publication number
DE60331638D1
DE60331638D1 DE60331638T DE60331638T DE60331638D1 DE 60331638 D1 DE60331638 D1 DE 60331638D1 DE 60331638 T DE60331638 T DE 60331638T DE 60331638 T DE60331638 T DE 60331638T DE 60331638 D1 DE60331638 D1 DE 60331638D1
Authority
DE
Germany
Prior art keywords
wonder
keratin
associations
tissue diseases
networks containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60331638T
Other languages
English (en)
Inventor
Dyke Mark E Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Keraplast Technologies Ltd
Original Assignee
Keraplast Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/119,477 external-priority patent/US6914126B2/en
Priority claimed from US10/127,523 external-priority patent/US7001987B2/en
Priority claimed from US10/133,885 external-priority patent/US6989437B2/en
Application filed by Keraplast Technologies Ltd filed Critical Keraplast Technologies Ltd
Application granted granted Critical
Publication of DE60331638D1 publication Critical patent/DE60331638D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/01Hydrolysed proteins; Derivatives thereof
    • A61K38/012Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/014Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
    • A61K38/015Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen from keratin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4741Keratin; Cytokeratin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42Block-or graft-polymers containing polysiloxane sequences
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42Block-or graft-polymers containing polysiloxane sequences
    • C08G77/452Block-or graft-polymers containing polysiloxane sequences containing nitrogen-containing sequences
    • C08G77/455Block-or graft-polymers containing polysiloxane sequences containing nitrogen-containing sequences containing polyamide, polyesteramide or polyimide sequences
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08HDERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00Macromolecular products derived from proteins
    • C08H1/06Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Colloid Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
DE60331638T 2002-04-10 2003-04-10 Keratin-netzwerke enthaltende wundverbände für gewebedefekte Expired - Fee Related DE60331638D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10/119,477 US6914126B2 (en) 2002-04-10 2002-04-10 Methods for producing, films comprising, and methods for using heterogenous crosslinked protein networks
US10/127,523 US7001987B2 (en) 2002-04-22 2002-04-22 Hydrogel with controllable mechanical, chemical, and biological properties and method for making same
US10/133,885 US6989437B2 (en) 2002-04-10 2002-04-26 Methods for producing, films comprising, and methods for using heterogeneous crosslinked protein networks
US39395802P 2002-07-05 2002-07-05
PCT/US2003/011364 WO2003086491A2 (en) 2002-04-10 2003-04-10 Tissue defect dressings comprising a keratin network

Publications (1)

Publication Number Publication Date
DE60331638D1 true DE60331638D1 (de) 2010-04-22

Family

ID=29255535

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60331638T Expired - Fee Related DE60331638D1 (de) 2002-04-10 2003-04-10 Keratin-netzwerke enthaltende wundverbände für gewebedefekte

Country Status (10)

Country Link
EP (2) EP1494728B1 (de)
JP (2) JP2005528938A (de)
AT (1) ATE460188T1 (de)
AU (5) AU2003221916A1 (de)
CA (2) CA2482262A1 (de)
DE (1) DE60331638D1 (de)
DK (1) DK1495048T3 (de)
ES (1) ES2460926T3 (de)
NZ (2) NZ536159A (de)
WO (4) WO2003087195A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4662948B2 (ja) * 2003-12-19 2011-03-30 ケラテク リミテッド ケラチンを含む創傷ケア製品
BRPI0513954A (pt) * 2004-07-30 2008-05-20 Matsushita Electric Ind Co Ltd transmissor sem fio e método de transmissão sem fio
US7439012B2 (en) 2004-08-17 2008-10-21 Wake Forest University Health Sciences Ambient stored blood plasma expanders containing keratose
US8920827B2 (en) 2005-10-21 2014-12-30 Wake Forest University Health Sciences Keratin bioceramic compositions
US7892573B2 (en) 2006-02-10 2011-02-22 Wake Forest University Health Sciences Nerve regeneration employing keratin biomaterials
US8273702B2 (en) 2006-02-17 2012-09-25 Wake Forest University Health Sciences Wound healing compositions containing keratin biomaterials
WO2007098053A2 (en) 2006-02-17 2007-08-30 Wake Forest University Health Sciences Coatings and biomedical implants formed from keratin biomaterials
US8101717B2 (en) 2006-11-13 2012-01-24 The University Of Sydney Use of tropoelastin for repair or restoration of tissue
GB0622694D0 (en) * 2006-11-14 2006-12-27 Serentis Ltd Use of opioid compounds in wound healing
JP5868592B2 (ja) * 2007-04-17 2016-02-24 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ ケラチンバイオマテリアルを含有する創傷治癒組成物
US9068162B2 (en) 2007-08-17 2015-06-30 Wake Forest University Health Sciences Keratin biomaterials for cell culture and methods of use
WO2010132673A1 (en) 2009-05-13 2010-11-18 Keraplast Technologies, Ltd. Biopolymer materials
CN102458795B (zh) 2009-06-22 2014-09-03 博里利斯股份公司 耐二氧化氯的聚乙烯管,其制备和用途
WO2011109808A1 (en) 2010-03-05 2011-09-09 Wake Forest University Health Sciences Controlled delivery system
WO2011112575A1 (en) 2010-03-08 2011-09-15 Wake Forest University Health Sciences Keratin biomaterials for treatment of ischemia
CA2818166C (en) 2010-11-17 2019-04-30 Wake Forest University Health Sciences Keratin compositions for treatment of bone deficiency or injury
US9700631B2 (en) 2011-08-17 2017-07-11 KeraNetics, LLC Low protein percentage gelling compositions
WO2013025928A2 (en) 2011-08-17 2013-02-21 Keranetics Llc Methods for extracting keratin proteins
US9827245B2 (en) 2013-03-15 2017-11-28 KeraNetics, LLC Keratin compositions comprising halofuginone
US9783905B2 (en) * 2014-12-30 2017-10-10 Rohm and Haas Electronic Mateirals LLC Reaction products of amino acids and epoxies
CN105126148B (zh) * 2015-08-03 2018-03-23 广东泰宝医疗科技股份有限公司 一种可视银释放敷料及其制备方法
CN114681673B (zh) * 2020-12-31 2023-05-23 杭州启明医疗器械股份有限公司 抗折痕的脱水交联生物材料及其制备方法和应用
US20250090719A1 (en) * 2021-07-30 2025-03-20 Regents Of The University Of Minnesota Biomaterials for embolization and drug delivery

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL274938A (de) * 1961-02-22
BE758986A (fr) * 1969-11-18 1971-04-30 Iws Nominee Co Ltd Procede de foulage de tissus textiles
DE2364525A1 (de) * 1973-12-24 1975-07-03 Henkel & Cie Gmbh Neue n-polyhydroxyalkyl-aminosaeuren, deren herstellung, sowie diese enthaltende hautpflege- und hautschutzmittel
EP0097907A3 (de) * 1982-06-25 1985-01-09 Flow General, Inc. Mikroträger für Zellkultur
US4474694A (en) * 1982-11-08 1984-10-02 Ralston Purina Company Modified protein adhesive binder and method of producing
JPS59155248A (ja) * 1983-02-22 1984-09-04 テルモ株式会社 被覆膜およびその製法
US4795629A (en) * 1987-07-06 1989-01-03 Chesebrough-Pond's Inc. Crosslinking of hair thiols using cystamine
JPH0725778B2 (ja) * 1987-10-21 1995-03-22 花王株式会社 リン酸エステル、その製造法およびそれを含有する洗浄剤組成物
GB9123251D0 (en) * 1991-11-01 1991-12-18 Croda Int Plc Protein-silicone copolymers
FR2692582B1 (fr) * 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
US5300285A (en) * 1992-10-13 1994-04-05 Dow Corning Corporation Permanent waving with silicones
US5505952A (en) * 1994-04-19 1996-04-09 United States Surgical Corporation Modified synthetic cross-linked amino acid polymers and medical devices formed therefrom
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6352699B1 (en) * 1997-04-04 2002-03-05 L'oreal Cosmetic or dermatological composition forming, on a keratin substrate, a film in cross-linked hybrid material
DE69821548T2 (de) * 1997-05-29 2004-12-30 Rohm And Haas Co. Vernetzte Polyaminsäure und deren Verfahren zur Herstellung
US6110487A (en) * 1997-11-26 2000-08-29 Keraplast Technologies Ltd. Method of making porous keratin scaffolds and products of same
US5932552A (en) * 1997-11-26 1999-08-03 Keraplast Technologies Ltd. Keratin-based hydrogel for biomedical applications and method of production
US5948432A (en) * 1997-11-26 1999-09-07 Keraplast Technologies Ltd. Keratin-based sheet material for biomedical applications and method of production
US7662409B2 (en) * 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US6371984B1 (en) * 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
DE60228573D1 (de) * 2001-05-30 2008-10-09 Chisso Corp Vernetztes elastin und verfahren zu deren herstellung
US6989437B2 (en) * 2002-04-10 2006-01-24 Keraplast Technologies, Ltd. Methods for producing, films comprising, and methods for using heterogeneous crosslinked protein networks

Also Published As

Publication number Publication date
WO2003086491A2 (en) 2003-10-23
AU2003221916A1 (en) 2003-10-27
WO2003087156A3 (en) 2004-09-02
DK1495048T3 (da) 2014-05-05
EP1495048A2 (de) 2005-01-12
WO2003087195A3 (en) 2004-07-15
AU2003234721A1 (en) 2003-10-27
CA2482215A1 (en) 2003-10-23
WO2003086491A3 (en) 2004-02-26
EP1494728B1 (de) 2010-03-10
AU2003221870A1 (en) 2003-10-27
WO2003087195A2 (en) 2003-10-23
NZ536159A (en) 2006-05-26
ES2460926T3 (es) 2014-05-16
EP1494728A2 (de) 2005-01-12
CA2482262A1 (en) 2003-10-23
WO2003087156A2 (en) 2003-10-23
AU2003224926A1 (en) 2003-10-27
ATE460188T1 (de) 2010-03-15
AU2003234721A8 (en) 2003-10-27
JP2005528938A (ja) 2005-09-29
WO2003087197A1 (en) 2003-10-23
AU2003221870B2 (en) 2009-06-04
EP1495048B1 (de) 2014-03-05
WO2003086491B1 (en) 2004-04-01
AU2009200774A1 (en) 2009-03-19
JP2006508027A (ja) 2006-03-09
NZ536158A (en) 2009-12-24

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee