DE60325718D1 - Nystatin-nanopartikelzusammensetzungen - Google Patents
Nystatin-nanopartikelzusammensetzungenInfo
- Publication number
- DE60325718D1 DE60325718D1 DE60325718T DE60325718T DE60325718D1 DE 60325718 D1 DE60325718 D1 DE 60325718D1 DE 60325718 T DE60325718 T DE 60325718T DE 60325718 T DE60325718 T DE 60325718T DE 60325718 D1 DE60325718 D1 DE 60325718D1
- Authority
- DE
- Germany
- Prior art keywords
- nystatin
- nanoparticle compositions
- directed
- composition
- particle size
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 229960000988 nystatin Drugs 0.000 title abstract 3
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 title abstract 3
- 239000002105 nanoparticle Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37759902P | 2002-05-06 | 2002-05-06 | |
| US38000802P | 2002-05-07 | 2002-05-07 | |
| US42338502P | 2002-11-04 | 2002-11-04 | |
| PCT/US2003/013833 WO2003094894A1 (en) | 2002-05-06 | 2003-05-05 | Nanoparticulate nystatin formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60325718D1 true DE60325718D1 (de) | 2009-02-26 |
Family
ID=29424512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60325718T Expired - Lifetime DE60325718D1 (de) | 2002-05-06 | 2003-05-05 | Nystatin-nanopartikelzusammensetzungen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20040018242A1 (de) |
| EP (1) | EP1503737B1 (de) |
| JP (1) | JP2005529911A (de) |
| AT (1) | ATE419835T1 (de) |
| AU (1) | AU2003234452A1 (de) |
| CA (1) | CA2484637A1 (de) |
| DE (1) | DE60325718D1 (de) |
| WO (1) | WO2003094894A1 (de) |
Families Citing this family (55)
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| US8236352B2 (en) | 1998-10-01 | 2012-08-07 | Alkermes Pharma Ireland Limited | Glipizide compositions |
| US8293277B2 (en) | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
| US20080102121A1 (en) * | 1998-11-02 | 2008-05-01 | Elan Pharma International Limited | Compositions comprising nanoparticulate meloxicam and controlled release hydrocodone |
| US7521068B2 (en) | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
| US7198795B2 (en) | 2000-09-21 | 2007-04-03 | Elan Pharma International Ltd. | In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions |
| JP4598399B2 (ja) * | 2002-02-04 | 2010-12-15 | エラン ファーマ インターナショナル，リミティド | 表面安定剤としてリゾチームを有するナノ粒子組成物 |
| WO2003103640A1 (en) * | 2002-06-10 | 2003-12-18 | Elan Pharma International, Ltd | Nanoparticulate formulations comprising hmg coa reductase inhibitor derivatives (“statins”), novel combinations thereof as well as manufacturing of these pharmaceutical compositions |
| US8512727B2 (en) * | 2003-03-03 | 2013-08-20 | Alkermes Pharma Ireland Limited | Nanoparticulate meloxicam formulations |
| US20100297252A1 (en) | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
| FR2855051B1 (fr) * | 2003-05-20 | 2006-08-25 | Oreal | Particules stabilisees en taille par copolymere diacide |
| WO2004103345A2 (fr) * | 2003-05-20 | 2004-12-02 | L'oreal | Particules stabilisees en taille par copolymere diacide |
| ATE509618T1 (de) | 2003-11-05 | 2011-06-15 | Elan Pharma Int Ltd | Nanoteilchenförmige zusammensetzungen mit einem peptid als oberflächenstabilisator |
| US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
| US7754230B2 (en) | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
| DK1758590T3 (da) | 2004-05-19 | 2011-11-21 | Los Angeles Biomed Res Inst | Anvendelse af et detergent til ikke-kirurgisk fjernelse af fedt |
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| ES2326354B1 (es) * | 2005-04-13 | 2010-07-08 | Elan Pharma International Limited | Composiciones de liberacion controlada y nanoparticuladas que comprenden derivados de prostaglandina. |
| KR20080008403A (ko) * | 2005-05-10 | 2008-01-23 | 엘란 파마 인터내셔널 리미티드 | 나노입자형 클로피도그렐 제제 |
| WO2006132752A1 (en) * | 2005-05-10 | 2006-12-14 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising vitamin k2 |
| CA2609296A1 (en) * | 2005-05-16 | 2006-11-16 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising a cephalosporin |
| US20100028439A1 (en) * | 2005-05-23 | 2010-02-04 | Elan Pharma International Limited | Nanoparticulate stabilized anti-hypertensive compositions |
| US20060292214A1 (en) * | 2005-06-03 | 2006-12-28 | Elan Pharma International Limited | Nanoparticulate acetaminophen formulations |
| WO2006133045A1 (en) * | 2005-06-03 | 2006-12-14 | Elan Pharma International, Limited | Nanoparticulate benidipine compositions |
| WO2006133046A2 (en) * | 2005-06-03 | 2006-12-14 | Elan Pharma International, Limited | Nanoparticulate imatinib mesylate formulations |
| WO2008073068A1 (en) | 2005-06-08 | 2008-06-19 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising cefditoren |
| US20070059371A1 (en) * | 2005-06-09 | 2007-03-15 | Elan Pharma International, Limited | Nanoparticulate ebastine formulations |
| US20070003615A1 (en) * | 2005-06-13 | 2007-01-04 | Elan Pharma International Limited | Nanoparticulate clopidogrel and aspirin combination formulations |
| JP2008543862A (ja) * | 2005-06-15 | 2008-12-04 | エラン ファーマ インターナショナル リミテッド | ナノ粒子アゼルニジピン製剤 |
| CA2614412A1 (en) * | 2005-07-07 | 2007-01-18 | Elan Pharma International, Limited | Nanoparticulate clarithromycin formulations |
| JP2009507925A (ja) * | 2005-09-13 | 2009-02-26 | エラン ファーマ インターナショナル リミテッド | ナノ粒子タダラフィル製剤 |
| EP2279727A3 (de) | 2005-09-15 | 2011-10-05 | Elan Pharma International Limited | Nanoteilchenförmige Aripiprazolformulierungen |
| SG170047A1 (en) | 2006-05-30 | 2011-04-29 | Elan Pharma Int Ltd | Nanoparticulate posaconazole formulations |
| JP2009543797A (ja) * | 2006-07-10 | 2009-12-10 | エラン ファーマ インターナショナル，リミティド | ナノ粒子ソラフェニブ製剤 |
| TW200820992A (en) * | 2006-07-12 | 2008-05-16 | Elan Corp Plc | Nanoparticulate formulations of modafinil |
| TWI405590B (zh) * | 2007-04-06 | 2013-08-21 | Activus Pharma Co Ltd | 微粉碎化有機化合物粒子之製法 |
| US20090118228A1 (en) * | 2007-11-07 | 2009-05-07 | Bristol-Myers Squibb Company | Carotenoid-containing compositions and methods |
| EP2070521A1 (de) | 2007-12-10 | 2009-06-17 | Bayer Schering Pharma Aktiengesellschaft | Nanopartikel mit modifizierter Oberfläche |
| US20090238867A1 (en) * | 2007-12-13 | 2009-09-24 | Scott Jenkins | Nanoparticulate Anidulafungin Compositions and Methods for Making the Same |
| WO2009117401A2 (en) * | 2008-03-21 | 2009-09-24 | Elan Pharama International Limited | Compositions for site-specific delivery of imatinib and methods of use |
| US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
| CN102448447A (zh) * | 2009-04-09 | 2012-05-09 | 阿尔科米斯制药爱尔兰有限公司 | 药物递送组合物 |
| ES2609415T3 (es) | 2009-05-27 | 2017-04-20 | Alkermes Pharma Ireland Limited | Reducción de agregación laminar en composiciones con nanopartículas de meloxicam |
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| US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
| CA2903433A1 (en) * | 2013-03-04 | 2014-09-12 | Vtv Therapeutics Llc | Stable glucokinase activator compositions |
| US8883747B1 (en) * | 2013-10-09 | 2014-11-11 | Craig W. Carver | Topical antifungal compositions and methods of use thereof |
| US11135158B2 (en) * | 2014-05-26 | 2021-10-05 | Michael Lee Martin | Medicated hard candy product for treating esophageal inflammation and a method using the same |
| EP3173067B1 (de) * | 2015-11-16 | 2018-11-14 | Istanbul Universitesi Rektorlugu | Mucoadhäsive bukkal in situ gelformulierung |
| WO2017134661A1 (en) * | 2016-02-04 | 2017-08-10 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Methods for disrupting biofilms |
| EP3295937A1 (de) * | 2016-09-20 | 2018-03-21 | Centre National De La Recherche Scientifique | Nanopartikel-prodrugs |
| US20240358651A1 (en) * | 2021-04-01 | 2024-10-31 | Snj Pharma Inc | Oral nanoparticles for bioactive compound, and method of preparing same |
| CN115363212B (zh) * | 2022-07-27 | 2024-04-05 | 海南师范大学 | 负载类胡萝卜素的海藻酸衍生物胶束、制备方法及其应用 |
| CN116686841B (zh) * | 2023-06-07 | 2024-07-19 | 丽珠集团新北江制药股份有限公司 | 一种含有多烯烃大环内酯类物质的液态组合物的制备方法 |
| CN119606873A (zh) * | 2025-02-14 | 2025-03-14 | 深圳市药欣生物科技有限公司 | 一种口腔凝胶剂及其应用 |
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| WO2000047187A1 (en) * | 1999-02-11 | 2000-08-17 | Kinetana Inc. | Serum albumin-based parenteral formulations of polyene macrolides |
| US6270806B1 (en) * | 1999-03-03 | 2001-08-07 | Elan Pharma International Limited | Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions |
| US6267989B1 (en) * | 1999-03-08 | 2001-07-31 | Klan Pharma International Ltd. | Methods for preventing crystal growth and particle aggregation in nanoparticulate compositions |
| US6413537B1 (en) * | 2000-03-10 | 2002-07-02 | Wisconsin Alumni Research Foundation | Nystatin formulation having reduced toxicity |
| US6316029B1 (en) * | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
| CA2420597C (en) * | 2000-08-31 | 2011-05-17 | Rtp Pharma Inc. | Milled particles |
| US6623761B2 (en) * | 2000-12-22 | 2003-09-23 | Hassan Emadeldin M. | Method of making nanoparticles of substantially water insoluble materials |
| US6660761B2 (en) * | 2002-02-06 | 2003-12-09 | Council Of Scientific And Industrial Research | Method of treatment for fungal infections with a synergistic formulation of antifungal agents |
-
2003
- 2003-05-05 CA CA002484637A patent/CA2484637A1/en not_active Abandoned
- 2003-05-05 JP JP2004502980A patent/JP2005529911A/ja active Pending
- 2003-05-05 AT AT03728678T patent/ATE419835T1/de not_active IP Right Cessation
- 2003-05-05 AU AU2003234452A patent/AU2003234452A1/en not_active Abandoned
- 2003-05-05 DE DE60325718T patent/DE60325718D1/de not_active Expired - Lifetime
- 2003-05-05 WO PCT/US2003/013833 patent/WO2003094894A1/en active Application Filing
- 2003-05-05 EP EP03728678A patent/EP1503737B1/de not_active Expired - Lifetime
- 2003-05-05 US US10/429,245 patent/US20040018242A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040018242A1 (en) | 2004-01-29 |
| EP1503737A1 (de) | 2005-02-09 |
| WO2003094894A1 (en) | 2003-11-20 |
| AU2003234452A1 (en) | 2003-11-11 |
| ATE419835T1 (de) | 2009-01-15 |
| JP2005529911A (ja) | 2005-10-06 |
| EP1503737B1 (de) | 2009-01-07 |
| CA2484637A1 (en) | 2003-11-20 |
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