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DE60325329D1 - Quaternäre terpensalze als biologisch aktive tenside - Google Patents

Quaternäre terpensalze als biologisch aktive tenside

Info

Publication number
DE60325329D1
DE60325329D1 DE60325329T DE60325329T DE60325329D1 DE 60325329 D1 DE60325329 D1 DE 60325329D1 DE 60325329 T DE60325329 T DE 60325329T DE 60325329 T DE60325329 T DE 60325329T DE 60325329 D1 DE60325329 D1 DE 60325329D1
Authority
DE
Germany
Prior art keywords
quaternary
terpene
salts
biologically active
active surfactants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60325329T
Other languages
English (en)
Inventor
Pavel A Krasutsky
Dmytro V Avilov
Tatiana Sergeeva
Dmytro Krasutsky
Oksana Kolomitsyna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota Twin Cities
University of Minnesota System
Original Assignee
University of Minnesota Twin Cities
University of Minnesota System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Minnesota Twin Cities, University of Minnesota System filed Critical University of Minnesota Twin Cities
Application granted granted Critical
Publication of DE60325329D1 publication Critical patent/DE60325329D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60325329T 2002-01-18 2003-01-21 Quaternäre terpensalze als biologisch aktive tenside Expired - Fee Related DE60325329D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34956402P 2002-01-18 2002-01-18
PCT/US2003/001666 WO2003062260A1 (en) 2002-01-18 2003-01-21 Triterpene quaternary salts as biologically active surfactants

Publications (1)

Publication Number Publication Date
DE60325329D1 true DE60325329D1 (de) 2009-01-29

Family

ID=27613290

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60325329T Expired - Fee Related DE60325329D1 (de) 2002-01-18 2003-01-21 Quaternäre terpensalze als biologisch aktive tenside

Country Status (10)

Country Link
US (5) US7199114B2 (de)
EP (1) EP1465914B1 (de)
JP (1) JP2005519913A (de)
AT (1) ATE417857T1 (de)
AU (1) AU2003205244B2 (de)
CA (1) CA2473799A1 (de)
DE (1) DE60325329D1 (de)
IL (1) IL163077A (de)
MX (1) MXPA04006953A (de)
WO (1) WO2003062260A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60325329D1 (de) * 2002-01-18 2009-01-29 Univ Minnesota Quaternäre terpensalze als biologisch aktive tenside
WO2006133314A2 (en) * 2005-06-08 2006-12-14 Regents Of The University Of Minnesota Synthesis of betulonic and betulinic aldehydes
FI121468B (fi) * 2006-06-07 2010-11-30 Valtion Teknillinen Betuliiniperäiset yhdisteet antimikrobisina aineina
JP2008123753A (ja) * 2006-11-09 2008-05-29 Koito Mfg Co Ltd 車両用灯具ユニット
CA2744908A1 (en) * 2007-12-04 2009-06-11 Myrexis, Inc. Compounds and therapeutic use thereof
LT2252283T (lt) 2008-01-11 2019-03-25 Reata Pharmaceuticals, Inc. Sintetiniai triterpenoidai ir jų panaudojimo būdai gydant ligą
WO2009090063A1 (en) * 2008-01-16 2009-07-23 Jado Technologies Gmbh Steroid sapogenin, androstane and triterpenoid sapogenin derivatives for the treatment and prevention of infectious diseases
MX2010011439A (es) 2008-04-18 2011-01-25 Reata Pharmaceuticals Inc Moduladores de inflamacion antioxidantes: derivados del acido oleanolico homologacion c-17.
SG190564A1 (en) 2008-04-18 2013-06-28 Reata Pharmaceuticals Inc Compounds including an anti-inflammatory pharmacore and methods of use
MX2010011437A (es) 2008-04-18 2010-12-20 Reata Pharmaceuticals Inc Moduladores antioxidantes de inflamacion: derivados del acido oleanolico con saturacion en el anillo c.
LT2276493T (lt) 2008-04-18 2019-01-10 Reata Pharmaceuticals, Inc. Antioksidaciniai uždegimo moduliatoriai: oleanolio rūgšties dariniai su amino ir kitomis modifikacijomis c-17
PT104607B (pt) * 2009-05-20 2012-03-23 Univ De Coimbra Derivados triterpenóides úteis como agentes antiproliferativos
EP2651902B1 (de) 2010-12-17 2017-11-08 Reata Pharmaceuticals, Inc. Tricyclische pyrazolyl- und pyrimidinylenone als antioxidante entzündungsmodulatoren
UY33946A (es) 2011-03-11 2012-08-31 Reata Pharmaceuticals Inc Derivados de c4-monometil triterpenoides y sus métodos de uso
WO2013163344A1 (en) 2012-04-27 2013-10-31 Reata Pharmaceuticals, Inc. 2.2-difluoropropionamide derivatives of bardoxolone methyl, polymorphic forms and methods of use thereof
US9556222B2 (en) 2012-06-15 2017-01-31 Reata Pharmaceuticals, Inc. A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof
WO2014040073A1 (en) 2012-09-10 2014-03-13 Reata Pharmaceuticals, Inc. C13-hydroxy derivatives of oleanolic acid and methods of use thereof
TWI630212B (zh) 2012-09-10 2018-07-21 瑞塔醫藥有限責任公司 丁香油素（ｏｌｅａｎｏｌｉｃ ａｃｉｄ）之ｃ１７－烷二基與烯二基衍生物及其使用方法
US9512094B2 (en) 2012-09-10 2016-12-06 Reata Pharmaceuticals, Inc. C17-heteroaryl derivatives of oleanolic acid and methods of use thereof
UY39092A (es) 2013-04-24 2021-03-26 Abbvie Inc Derivados de 2,2-difluoropropanamida y metil bardoxolona, formas polimórficas y métodos de uso
CN104387440A (zh) * 2014-11-07 2015-03-04 上海应用技术学院 一种白桦脂醇氨基酸酯化合物及其制备方法和用途
US11584775B2 (en) 2015-09-23 2023-02-21 Reata Pharmaceuticals, Inc. C4-modified oleanolic acid derivatives for inhibition of IL-17 and other uses
WO2019232208A1 (en) * 2018-05-30 2019-12-05 Translate Bio, Inc. Cationic lipids comprising a steroidal moiety
WO2019246461A1 (en) 2018-06-20 2019-12-26 Reata Pharmaceuticals, Inc. Cysteine-dependent inverse agonists of nuclear receptors ror-gamma/ror-gamma-t and methods of treating diseases or disorders therewith
RU2725873C2 (ru) * 2018-08-20 2020-07-07 Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук Способ получения 1-(3-гидрокси, 28-ацетоксилуп-20(29)-ен-30-ил)-пиридиний бромида и его применение в качестве средства с антибактериальной и противогрибковой активностью
CN113876595A (zh) * 2021-10-18 2022-01-04 东华大学 桦木醇基季铵盐类抗菌型有机单体及其复合树脂的用途和其复合树脂的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1454749A (en) * 1972-11-29 1976-11-03 Akzo Nv 2beta, 16beta-diamino-androstanes and their preparation
ES423577A1 (es) * 1974-02-23 1976-05-16 Landerlan S A Procedimiento de obtencion de derivados de acidos triterpe-nicos.
CH602794A5 (de) * 1974-10-29 1978-08-15 Hoffmann La Roche
KR910008736B1 (ko) * 1989-06-13 1991-10-19 태평양화학주식회사 4급암모니움-치환된 사포닌 에테르 유도체 및 그 제조방법
US6303589B1 (en) 1998-12-08 2001-10-16 Micro Flo Company Pentacyclic triterpenes
DE60325329D1 (de) * 2002-01-18 2009-01-29 Univ Minnesota Quaternäre terpensalze als biologisch aktive tenside

Also Published As

Publication number Publication date
US20070259842A1 (en) 2007-11-08
ATE417857T1 (de) 2009-01-15
JP2005519913A (ja) 2005-07-07
US7410958B2 (en) 2008-08-12
EP1465914A1 (de) 2004-10-13
IL163077A (en) 2009-06-15
AU2003205244B2 (en) 2009-01-08
US7199114B2 (en) 2007-04-03
MXPA04006953A (es) 2005-06-20
US20070088009A1 (en) 2007-04-19
WO2003062260A1 (en) 2003-07-31
US20050059642A1 (en) 2005-03-17
US20070259839A1 (en) 2007-11-08
CA2473799A1 (en) 2003-07-31
EP1465914B1 (de) 2008-12-17
US20070244081A1 (en) 2007-10-18

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee