DE60322682D1 - Verfahren zur überwachung der typ-ii-kollagenabbau in knorpeln - Google Patents
Verfahren zur überwachung der typ-ii-kollagenabbau in knorpelnInfo
- Publication number
- DE60322682D1 DE60322682D1 DE60322682T DE60322682T DE60322682D1 DE 60322682 D1 DE60322682 D1 DE 60322682D1 DE 60322682 T DE60322682 T DE 60322682T DE 60322682 T DE60322682 T DE 60322682T DE 60322682 D1 DE60322682 D1 DE 60322682D1
- Authority
- DE
- Germany
- Prior art keywords
- collagen
- cartles
- dissipation
- collagen type
- monitoring type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108010041390 Collagen Type II Proteins 0.000 title abstract 3
- 102000000503 Collagen Type II Human genes 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000012544 monitoring process Methods 0.000 title abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 102000029816 Collagenase Human genes 0.000 abstract 1
- 108060005980 Collagenase Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000002917 arthritic effect Effects 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 108010093679 collagen type II (108-116) Proteins 0.000 abstract 1
- 229960002424 collagenase Drugs 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/84—Bones; tendons; teeth; cartilage
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Tires In General (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36392602P | 2002-03-13 | 2002-03-13 | |
| DKPA200200380 | 2002-03-13 | ||
| PCT/EP2003/002561 WO2003076947A2 (en) | 2002-03-13 | 2003-03-12 | Method for monitoring collagen type ii degradation in cartilage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60322682D1 true DE60322682D1 (de) | 2008-09-18 |
Family
ID=27806429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60322682T Expired - Lifetime DE60322682D1 (de) | 2002-03-13 | 2003-03-12 | Verfahren zur überwachung der typ-ii-kollagenabbau in knorpeln |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7410770B2 (de) |
| EP (1) | EP1485718B1 (de) |
| AT (1) | ATE403873T1 (de) |
| AU (1) | AU2003222759A1 (de) |
| DE (1) | DE60322682D1 (de) |
| ES (1) | ES2311696T3 (de) |
| WO (1) | WO2003076947A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010003016A2 (en) * | 2008-07-04 | 2010-01-07 | Axial Biotech, Inc | Genetic markers associated with degenerative disc disease and uses thereof |
| KR101705353B1 (ko) * | 2013-10-17 | 2017-02-13 | 경북대학교 산학협력단 | ApoPep-1 펩타이드 프로브를 포함하는 골관절염 조기진단용 시약 |
| EP3233909A1 (de) * | 2014-12-19 | 2017-10-25 | Université de Liège | Coll2-1-peptid und dessen nitrierte form als therapeutische targets zur behandlung von osteoarthritis |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5702909A (en) * | 1987-11-06 | 1997-12-30 | Washington Research Foundation | Methods of detecting collagen type II degradation in vivo |
| US4973666A (en) * | 1987-11-06 | 1990-11-27 | Washington Research Foundation | Peptide fragments containing HP and LP cross-links |
| US6132976A (en) * | 1992-12-04 | 2000-10-17 | Shriners Hospitals For Children | Immunoassays for the measurement of collagen denaturation and cleavage in cartilage |
| US6110689A (en) * | 1994-01-21 | 2000-08-29 | Osteometer A/S | Method of assaying collagen fragments in body fluids, a test kit and means for carrying out the method and use of the method to diagnose the presence of disorders associated with the metabolism of collagen |
| GB9928052D0 (en) | 1999-11-26 | 2000-01-26 | Osteometer Biotech As | Assay of isomerised and/or optically inverted proteins and protein fragments |
| US7148020B2 (en) * | 2001-07-12 | 2006-12-12 | Arexis Ab | Triple polypeptide complexes |
-
2003
- 2003-03-12 ES ES03718685T patent/ES2311696T3/es not_active Expired - Lifetime
- 2003-03-12 US US10/507,498 patent/US7410770B2/en not_active Expired - Fee Related
- 2003-03-12 WO PCT/EP2003/002561 patent/WO2003076947A2/en active IP Right Grant
- 2003-03-12 AU AU2003222759A patent/AU2003222759A1/en not_active Abandoned
- 2003-03-12 EP EP03718685A patent/EP1485718B1/de not_active Expired - Lifetime
- 2003-03-12 AT AT03718685T patent/ATE403873T1/de not_active IP Right Cessation
- 2003-03-12 DE DE60322682T patent/DE60322682D1/de not_active Expired - Lifetime
-
2008
- 2008-08-07 US US12/222,352 patent/US7728112B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20090042220A1 (en) | 2009-02-12 |
| US7410770B2 (en) | 2008-08-12 |
| AU2003222759A8 (en) | 2003-09-22 |
| WO2003076947A3 (en) | 2004-04-08 |
| AU2003222759A1 (en) | 2003-09-22 |
| WO2003076947A2 (en) | 2003-09-18 |
| US20050170429A1 (en) | 2005-08-04 |
| EP1485718B1 (de) | 2008-08-06 |
| EP1485718A2 (de) | 2004-12-15 |
| ES2311696T3 (es) | 2009-02-16 |
| US7728112B2 (en) | 2010-06-01 |
| ATE403873T1 (de) | 2008-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |