[go: up one dir, main page]

DE60313365D1 - 4-Aryl-4-(Naphth-1-ylmethylamino)methyl-Piperidin-Verbindungen und deren Verwendung - Google Patents

4-Aryl-4-(Naphth-1-ylmethylamino)methyl-Piperidin-Verbindungen und deren Verwendung

Info

Publication number
DE60313365D1
DE60313365D1 DE60313365T DE60313365T DE60313365D1 DE 60313365 D1 DE60313365 D1 DE 60313365D1 DE 60313365 T DE60313365 T DE 60313365T DE 60313365 T DE60313365 T DE 60313365T DE 60313365 D1 DE60313365 D1 DE 60313365D1
Authority
DE
Germany
Prior art keywords
sub
ylmethylamino
naphth
aryl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60313365T
Other languages
English (en)
Other versions
DE60313365T2 (de
Inventor
Peter Bernstein
Paul Warwick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE60313365D1 publication Critical patent/DE60313365D1/de
Publication of DE60313365T2 publication Critical patent/DE60313365T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Addiction (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60313365T 2002-12-20 2003-12-18 4-Aryl-4-(Naphth-1-ylmethylamino)methyl-Piperidin-Verbindungen und deren Verwendung Expired - Fee Related DE60313365T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43513002P 2002-12-20 2002-12-20
US435130P 2002-12-20
PCT/SE2003/002004 WO2004056771A1 (en) 2002-12-20 2003-12-18 Piperidine amine compounds and their use

Publications (2)

Publication Number Publication Date
DE60313365D1 true DE60313365D1 (de) 2007-05-31
DE60313365T2 DE60313365T2 (de) 2007-12-27

Family

ID=32682165

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60313365T Expired - Fee Related DE60313365T2 (de) 2002-12-20 2003-12-18 4-Aryl-4-(Naphth-1-ylmethylamino)methyl-Piperidin-Verbindungen und deren Verwendung

Country Status (8)

Country Link
US (1) US20060058352A1 (de)
EP (1) EP1581495B1 (de)
JP (1) JP2006512363A (de)
AT (1) ATE360001T1 (de)
AU (1) AU2003291589A1 (de)
DE (1) DE60313365T2 (de)
ES (1) ES2286470T3 (de)
WO (1) WO2004056771A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006502157A (ja) * 2002-09-09 2006-01-19 アストラゼネカ・アクチエボラーグ ナフチルエーテル化合物及びそれらの使用
WO2005037269A1 (ja) * 2003-10-21 2005-04-28 Dainippon Sumitomo Pharma Co., Ltd. 新規ピペリジン誘導体
GB0412865D0 (en) 2004-06-09 2004-07-14 Glaxo Group Ltd Chemical compounds
US7494986B2 (en) 2004-07-20 2009-02-24 Bristol-Myers Squibb Company Cycloalkylamine derivatives as NK-1/SSRI antagonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3693820A (en) * 1971-06-03 1972-09-26 Robert P Linkletter Safety closure cap
US3931891A (en) * 1974-10-11 1976-01-13 Peppler Stanley R K Pill container with pocket
FR2603871B1 (fr) * 1986-09-16 1988-12-02 Morel Simone Capsule de securite formant bouchon pour flacons et objets analogues
GB9601960D0 (en) * 1996-01-31 1996-04-03 Galton Fenzi Miles D M Containers
US5908125A (en) * 1997-04-16 1999-06-01 Weatherchem Corporation Child-resistant screw-on cap and bottle
IL140770A0 (en) * 1998-07-10 2002-02-10 Astrazeneca Ab N-substituted naphthalene carboxamides as neurokinin-receptor antagonists
GB9907571D0 (en) * 1999-04-06 1999-05-26 Zeneca Ltd Compounds
AU2003253558A1 (en) * 2002-08-29 2004-03-19 Astrazeneca Ab Naphthamide derivatives and their use

Also Published As

Publication number Publication date
ES2286470T3 (es) 2007-12-01
DE60313365T2 (de) 2007-12-27
EP1581495A1 (de) 2005-10-05
EP1581495B1 (de) 2007-04-18
AU2003291589A1 (en) 2004-07-14
JP2006512363A (ja) 2006-04-13
WO2004056771A1 (en) 2004-07-08
ATE360001T1 (de) 2007-05-15
US20060058352A1 (en) 2006-03-16

Similar Documents

Publication Publication Date Title
SE0104251D0 (sv) Novel compounds
NO20044995L (no) Heterosykliske forbindelser
CY1115925T1 (el) Παραγωγα πυριδαζινονης
DE60334536D1 (de) Furylverbindungen
SE0401971D0 (sv) Piperidne derivatives
CY1114574T1 (el) Παραγωγα πιπεριδινης και πιπεραζινης για τη θεραπεια ογκων
ATE477256T1 (de) Thienylverbindungen
CY1105047T1 (el) Ενωσεις πυριδοπυριμιδινονης, η μεθοδος παρασκευης τους και φαρμακευτικες συνθεσεις που τις περιεχουν
MX2007003470A (es) Compuestos de carbonilo los cuales pueden utilizarse como inhibidores del factor de coagulacion xa.
SE0104248D0 (sv) Method of treatment
SE0401969D0 (sv) Piperidine derivatives
SE0203302D0 (sv) Novel Compounds
SE0301699D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
DE60313365D1 (de) 4-Aryl-4-(Naphth-1-ylmethylamino)methyl-Piperidin-Verbindungen und deren Verwendung
TW200504059A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
ATE416162T1 (de) Naphthamidderivate und deren verwendung
AU2002359150A8 (en) Therapeutic heterocycles
NO20052994L (no) Nye fosforamidderivater.
CY1106472T1 (el) Η χρηση των παραγωγων υδροξυπυριδονης στην επουλωση πληγων
DE60224805D1 (de) 1-glycinyl-4-(1-methylpiperidin-4-yl)piperazine un
SE0301442D0 (sv) Diarylmethylidene piperidine derivatives, preparations therof and uses thereof
NO20053805L (no) Diarylmetylindenpiperidinderivater, framgangsmate for fremstilling derav, og anvendelse derav
TW200500356A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
NO20063617L (no) Diarylmetylidenpiperidinderivater, fremstilling og anvendelse derav
MXPA05012117A (es) Derivados de diarilmetiliden piperidina, preparaciones de los mismos y usos de los mismos.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee