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DE60237003D1 - USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH - Google Patents

USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH

Info

Publication number
DE60237003D1
DE60237003D1 DE60237003T DE60237003T DE60237003D1 DE 60237003 D1 DE60237003 D1 DE 60237003D1 DE 60237003 T DE60237003 T DE 60237003T DE 60237003 T DE60237003 T DE 60237003T DE 60237003 D1 DE60237003 D1 DE 60237003D1
Authority
DE
Germany
Prior art keywords
hair growth
cyclosporin derivatives
position cyclosporin
active ingredient
cyclosporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60237003T
Other languages
German (de)
Inventor
Sang-Nyun Kim
Ho-Jeong Ahn
Chang-Woo Lee
Min-Ho Lee
Jung-Hun Kim
Jong-Il Kim
Seung-Jin Kim
Ho-Song Cho
Heon-Sik Lee
Hyung-Jin Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LG H&H Co Ltd
Original Assignee
LG Household and Health Care Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LG Household and Health Care Ltd filed Critical LG Household and Health Care Ltd
Application granted granted Critical
Publication of DE60237003D1 publication Critical patent/DE60237003D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention discloses a hair growth promoting agent comprising a cyclosporin derivative as an active ingredient, and more particularly, a hair growth promoting agent comprising a cyclosporin A derivative substituted in the 3-position as an active ingredient.
DE60237003T 2001-05-11 2002-05-11 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH Expired - Lifetime DE60237003D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2001-0025682A KR100465012B1 (en) 2001-05-11 2001-05-11 Use of 3-position cyclosporin derivatives for hair growth
PCT/KR2002/000879 WO2002092032A1 (en) 2001-05-11 2002-05-11 Use of 3-position cyclosporin derivatives for hair growth

Publications (1)

Publication Number Publication Date
DE60237003D1 true DE60237003D1 (en) 2010-08-26

Family

ID=19709334

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60237003T Expired - Lifetime DE60237003D1 (en) 2001-05-11 2002-05-11 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH

Country Status (17)

Country Link
US (2) US6790830B2 (en)
EP (1) EP1387660B1 (en)
JP (1) JP4214181B2 (en)
KR (1) KR100465012B1 (en)
CN (1) CN1248671C (en)
AT (1) ATE473730T1 (en)
AU (1) AU2002258271B2 (en)
BR (1) BRPI0209619B8 (en)
CA (1) CA2446971C (en)
DE (1) DE60237003D1 (en)
ES (1) ES2348225T3 (en)
MX (1) MXPA03010027A (en)
PL (1) PL208536B1 (en)
RU (1) RU2291682C2 (en)
TR (1) TR200301931T2 (en)
WO (1) WO2002092032A1 (en)
ZA (1) ZA200308532B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020039528A (en) * 2000-11-22 2002-05-27 조명재 Use of cyclosporin 7-thioamide derivatives for hair growth
KR100865211B1 (en) * 2001-10-26 2008-10-23 주식회사 엘지생활건강 Non-immune [gamma-hydroxy-en-methyl-leucine 4] anti-cancer chemotherapy inhibitors using cyclosporine derivatives as an active ingredient
US6987090B2 (en) * 2002-05-09 2006-01-17 Lg Household & Health Care Ltd. Use of 3-position cyclosporin derivatives for hair growth
US7538084B2 (en) 2003-03-17 2009-05-26 Amr Technology, Inc. Cyclosporins
US7511013B2 (en) 2004-09-29 2009-03-31 Amr Technology, Inc. Cyclosporin analogues and their pharmaceutical uses
US7378391B2 (en) 2004-09-29 2008-05-27 Amr Technology, Inc. Cyclosporin alkyne analogues and their pharmaceutical uses
EP1812037A4 (en) 2004-10-06 2009-11-11 Amr Technology Inc Novel cyclosporin alkynes and their utility as pharmaceutical agents
WO2007103311A2 (en) * 2006-03-06 2007-09-13 Rouse Martin D Jr Thermal vaporizer apparatus
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
DE102008060549A1 (en) 2008-12-04 2010-06-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Drug-peptide construct for extracellular accumulation
US20100305047A1 (en) * 2009-05-27 2010-12-02 Allergan, Inc. Cyclosporin derivatives for enhancing the growth of hair
WO2010146622A1 (en) 2009-06-15 2010-12-23 花王株式会社 Nfat signal inhibitor and calcineurin inhibitor
CN107496902B (en) 2010-12-15 2022-01-18 康卓维尔制药公司 Cyclosporin-like molecules modified at amino acid 1 and 3
RU2479872C1 (en) * 2012-01-11 2013-04-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации Method for correction of ischemic disorders caused by reperfusion liver injury
EP2705856A1 (en) 2012-09-07 2014-03-12 Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. Compounds for the treatment of neurodegenerative disorders
KR102469342B1 (en) * 2021-06-14 2022-11-21 주식회사 오리엔트바이오 Controlled-release intralesional injection composition comprising cyclic peptides and method for preparing same

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60243008A (en) 1984-05-17 1985-12-03 Wakamoto Pharmaceut Co Ltd Hair producing and growing tonic
EP0194972B1 (en) * 1985-03-11 1992-07-29 Sandoz Ag Novel cyclosporins
JPS6219512A (en) 1985-07-17 1987-01-28 Shiseido Co Ltd Hair tonic
JPS6219513A (en) 1985-07-17 1987-01-28 Shiseido Co Ltd Hair tonic
CH679119A5 (en) 1988-05-13 1991-12-31 Sandoz Ag
US5284826A (en) * 1989-07-24 1994-02-08 Sandoz Ltd. 0-hydroxyethyl and acyloxyethyl derivatives of [ser]8 cyclosporins
GB8916901D0 (en) * 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
GB9203886D0 (en) * 1992-02-24 1992-04-08 Sandoz Ltd Improvements in or relating to organic compounds
JPH07316023A (en) * 1994-05-26 1995-12-05 Shiseido Co Ltd Hair tonic
AU722858B2 (en) * 1995-07-17 2000-08-10 Scynexis, Inc. Cyclosporin derivatives having an anti-HIV effect
FR2757521B1 (en) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa NOVEL CYCLOSPORIN DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
JP4477777B2 (en) * 1998-06-12 2010-06-09 シネクシス・インコーポレイテツド New cyclosporine
FR2780061B1 (en) * 1998-06-22 2001-09-07 Rhone Poulenc Rorer Sa NOVEL PROCESS FOR THE PREPARATION OF CYCLOSPORIN DERIVATIVES
WO2000051558A1 (en) 1999-03-05 2000-09-08 The University Of Texas Southwestern Medical Center Method of treating hair loss using non-immunosuppressive compounds
JP2003514000A (en) * 1999-11-19 2003-04-15 エル・ジー ハウスホールド アンド ヘルスケア リミティッド Hair growth promoting agent containing cyclosporin derivative
KR100316604B1 (en) * 1999-11-19 2001-12-12 성재갑 Use of a nonimmunosuppressive cyclosporin A derivative for hair growth
US6521595B1 (en) * 1999-11-19 2003-02-18 Lg Chemical, Ltd. Nonimmunosuppressive [γ-hydroxy-methylleucine4] cyclosporin A, hair growth stimulator and external composition for skin using the same
KR100360716B1 (en) * 2000-11-22 2002-11-13 주식회사 엘지생활건강 Use of cyclosporin A 7-thioamide derivatives for hair growth
KR20020039528A (en) * 2000-11-22 2002-05-27 조명재 Use of cyclosporin 7-thioamide derivatives for hair growth
KR100681670B1 (en) * 2001-02-14 2007-02-09 주식회사 엘지생활건강 [Gamma Hydroxy En-methyl-L-Leucine 9] Hair Growth Accelerator Having Cyclosporin A as an Active Ingredient
KR100695610B1 (en) * 2001-05-15 2007-03-14 주식회사 엘지생활건강 Scalp and transdermal formulations containing [gamma hydroxy en-methyl lysine 4] cyclosporin derivatives as non-immune hair growth ingredients
KR100695611B1 (en) * 2001-05-17 2007-03-14 주식회사 엘지생활건강 [Gamma Hydroxy-En-methyl-L-Leucine 4] Hair Growth Accelerator Using Cyclosporin Derivative as an Active Ingredient

Also Published As

Publication number Publication date
RU2291682C2 (en) 2007-01-20
ES2348225T3 (en) 2010-12-01
JP4214181B2 (en) 2009-01-28
PL208536B1 (en) 2011-05-31
CN1248671C (en) 2006-04-05
BR0209619A (en) 2004-03-30
RU2003135846A (en) 2005-03-27
CA2446971C (en) 2011-07-05
US20030186857A1 (en) 2003-10-02
AU2002258271B2 (en) 2006-06-29
EP1387660B1 (en) 2010-07-14
US6790830B2 (en) 2004-09-14
ATE473730T1 (en) 2010-07-15
BRPI0209619B1 (en) 2015-05-19
TR200301931T2 (en) 2004-09-21
US6762164B2 (en) 2004-07-13
ZA200308532B (en) 2004-07-01
JP2004530685A (en) 2004-10-07
MXPA03010027A (en) 2005-09-08
US20030207798A1 (en) 2003-11-06
EP1387660A4 (en) 2006-05-17
KR20020086041A (en) 2002-11-18
WO2002092032A1 (en) 2002-11-21
PL366407A1 (en) 2005-01-24
KR100465012B1 (en) 2005-01-13
CA2446971A1 (en) 2002-11-21
BRPI0209619B8 (en) 2021-05-25
CN1507339A (en) 2004-06-23
EP1387660A1 (en) 2004-02-11

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