DE60236386D1 - Verfahren und pharmazeutische Zusammensetzung zur Vorbeugung und/oder Behandlung des Syndroms der systemischen entzündlichen Reaktion - Google Patents
Verfahren und pharmazeutische Zusammensetzung zur Vorbeugung und/oder Behandlung des Syndroms der systemischen entzündlichen ReaktionInfo
- Publication number
- DE60236386D1 DE60236386D1 DE60236386T DE60236386T DE60236386D1 DE 60236386 D1 DE60236386 D1 DE 60236386D1 DE 60236386 T DE60236386 T DE 60236386T DE 60236386 T DE60236386 T DE 60236386T DE 60236386 D1 DE60236386 D1 DE 60236386D1
- Authority
- DE
- Germany
- Prior art keywords
- systemic inflammatory
- syndrome
- prevention
- treatment
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- 230000009885 systemic effect Effects 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 108010054218 Factor VIII Proteins 0.000 abstract 1
- 102000001690 Factor VIII Human genes 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 206010040070 Septic Shock Diseases 0.000 abstract 1
- 206010051379 Systemic Inflammatory Response Syndrome Diseases 0.000 abstract 1
- 108090000190 Thrombin Proteins 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000009190 disseminated intravascular coagulation Diseases 0.000 abstract 1
- 229960000301 factor viii Drugs 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000036303 septic shock Effects 0.000 abstract 1
- 229960004072 thrombin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26140501P | 2001-01-11 | 2001-01-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60236386D1 true DE60236386D1 (de) | 2010-07-01 |
Family
ID=22993164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60236386T Expired - Lifetime DE60236386D1 (de) | 2001-01-11 | 2002-01-11 | Verfahren und pharmazeutische Zusammensetzung zur Vorbeugung und/oder Behandlung des Syndroms der systemischen entzündlichen Reaktion |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1222929B8 (de) |
| AT (1) | ATE468136T1 (de) |
| CY (1) | CY1110781T1 (de) |
| DE (1) | DE60236386D1 (de) |
| DK (1) | DK1222929T3 (de) |
| ES (1) | ES2346189T3 (de) |
| PT (1) | PT1222929E (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005016455A2 (en) * | 2003-08-14 | 2005-02-24 | D. Collen Research Foundation Vzw | Antibodies against factor viii with modified glycosylation in the variable region |
| US7829085B2 (en) | 1999-07-14 | 2010-11-09 | Life Sciences Research Partners Vzw | Methods of treating hemostasis disorders using antibodies binding the C1 domain of factor VIII |
| TW200407335A (en) | 2002-07-22 | 2004-05-16 | Chugai Pharmaceutical Co Ltd | Non-neutralizing antibody to inhibit the inactivation of activated protein C |
| US20060167230A1 (en) * | 2003-01-20 | 2006-07-27 | Takaki Koga | Anti-pci neutralizing antibody |
| US8119137B2 (en) * | 2004-12-23 | 2012-02-21 | Csl Behring Gmbh | Prevention of thrombus formation and/or stabilization with inhibitors of factor XII or activated factor XII |
| JP2009502149A (ja) | 2005-07-29 | 2009-01-29 | ライフ・サイエンシーズ・リサーチ・パートナーズ・フェレニゲング・ゾンデル・ウィンストーメルク | 新規な抗第viii因子抗体 |
| CN102234641A (zh) * | 2010-05-05 | 2011-11-09 | 杭州星博生物科技有限公司 | 一种快速获取特异性人源抗体可变区基因序列的方法 |
| DE102013005184A1 (de) | 2013-03-20 | 2014-09-25 | fzmb GmbH, Forschungszentrum für Medizintechnik und Biotechnologie | Verfahren zur Funktionalisierung einer Oberfläche |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA24512A1 (fr) | 1996-01-17 | 1998-12-31 | Univ Vermont And State Agrienl | Procede pour la preparation d'agents anticoagulants utiles dans le traitement de la thrombose |
| JP4297207B2 (ja) | 1999-07-14 | 2009-07-15 | ライフ・サイエンシーズ・リサーチ・パートナーズ・フェレニゲング・ゾンデル・ウィンストーメルク | 止血障害処置のための治療組成物に使用するためのリガンド |
-
2002
- 2002-01-11 PT PT02447005T patent/PT1222929E/pt unknown
- 2002-01-11 ES ES02447005T patent/ES2346189T3/es not_active Expired - Lifetime
- 2002-01-11 DE DE60236386T patent/DE60236386D1/de not_active Expired - Lifetime
- 2002-01-11 DK DK02447005.6T patent/DK1222929T3/da active
- 2002-01-11 EP EP02447005A patent/EP1222929B8/de not_active Expired - Lifetime
- 2002-01-11 AT AT02447005T patent/ATE468136T1/de active
-
2010
- 2010-08-10 CY CY20101100748T patent/CY1110781T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1222929T3 (da) | 2010-09-06 |
| ES2346189T3 (es) | 2010-10-13 |
| EP1222929A2 (de) | 2002-07-17 |
| EP1222929B8 (de) | 2010-07-07 |
| EP1222929A3 (de) | 2002-09-18 |
| EP1222929B1 (de) | 2010-05-19 |
| PT1222929E (pt) | 2010-08-18 |
| CY1110781T1 (el) | 2015-06-10 |
| ATE468136T1 (de) | 2010-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: LIFE SCIENCES RESEARCH PARTNERS VZW, LEUVEN, BE |
|
| 8364 | No opposition during term of opposition |