DE60227297D1 - Biochip-Lesegerät - Google Patents
Biochip-LesegerätInfo
- Publication number
- DE60227297D1 DE60227297D1 DE60227297T DE60227297T DE60227297D1 DE 60227297 D1 DE60227297 D1 DE 60227297D1 DE 60227297 T DE60227297 T DE 60227297T DE 60227297 T DE60227297 T DE 60227297T DE 60227297 D1 DE60227297 D1 DE 60227297D1
- Authority
- DE
- Germany
- Prior art keywords
- biochip reader
- biochip
- reader
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Optical Measuring Cells (AREA)
- Microscoopes, Condenser (AREA)
- Facsimile Scanning Arrangements (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001139678 | 2001-05-10 | ||
JP2001140137 | 2001-05-10 | ||
JP2001140835 | 2001-05-11 | ||
JP2002031668A JP3741051B2 (ja) | 2001-05-10 | 2002-02-08 | バイオチップ読取装置 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60227297D1 true DE60227297D1 (de) | 2008-08-07 |
Family
ID=27482257
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60227297T Expired - Lifetime DE60227297D1 (de) | 2001-05-10 | 2002-03-21 | Biochip-Lesegerät |
DE60228769T Expired - Lifetime DE60228769D1 (de) | 2001-05-10 | 2002-03-21 | Ein System umfassend einen Biochip und einen Biochip-Lesegerät |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60228769T Expired - Lifetime DE60228769D1 (de) | 2001-05-10 | 2002-03-21 | Ein System umfassend einen Biochip und einen Biochip-Lesegerät |
Country Status (4)
Country | Link |
---|---|
US (4) | US6867860B2 (de) |
EP (6) | EP1256795A3 (de) |
JP (1) | JP3741051B2 (de) |
DE (2) | DE60227297D1 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003057557A (ja) * | 2001-08-09 | 2003-02-26 | Yokogawa Electric Corp | バイオチップ読取装置 |
US7312432B2 (en) * | 2002-07-08 | 2007-12-25 | Dmetrix, Inc. | Single axis illumination for multi-axis imaging system |
US7285424B2 (en) | 2002-08-27 | 2007-10-23 | Kimberly-Clark Worldwide, Inc. | Membrane-based assay devices |
DE10307802A1 (de) * | 2003-02-24 | 2004-09-09 | Advalytix Ag | Analyseverfahren und -Vorrichtung zur Analyse von spezifischen Bindungsreaktionen |
JP2004347454A (ja) * | 2003-05-22 | 2004-12-09 | Mitsubishi Rayon Co Ltd | シェーディング補正方法 |
CN100338444C (zh) * | 2003-06-13 | 2007-09-19 | 上海爱普特仪器有限公司 | 一种激光强度调节装置 |
US7002750B2 (en) * | 2003-11-06 | 2006-02-21 | Ann-Lun Lee | Image capturing device |
US7943395B2 (en) | 2003-11-21 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Extension of the dynamic detection range of assay devices |
US20050112703A1 (en) | 2003-11-21 | 2005-05-26 | Kimberly-Clark Worldwide, Inc. | Membrane-based lateral flow assay devices that utilize phosphorescent detection |
TWI258584B (en) * | 2003-12-09 | 2006-07-21 | Ind Tech Res Inst | Fluorescent-assisted tester |
WO2005083432A1 (fr) * | 2003-12-19 | 2005-09-09 | Chengdu Kuachang Medical Industrial Limited | Procede et dispositif d'analyse de puce multireacteur |
JP4370900B2 (ja) * | 2003-12-22 | 2009-11-25 | 横河電機株式会社 | バイオチップ基板保持方法およびバイオチップ読取装置 |
JP2005181244A (ja) * | 2003-12-24 | 2005-07-07 | Yokogawa Electric Corp | 光量分布補正方法およびバイオチップ読取装置 |
JP4232648B2 (ja) * | 2004-02-16 | 2009-03-04 | コニカミノルタセンシング株式会社 | 反射光測定装置 |
DE102004011387B4 (de) * | 2004-03-05 | 2010-04-29 | L.U.M. Gmbh | Verfahren und Vorrichtung zur Charakterisierung von multiplen Proben einer Dispersion |
DE102004015488B4 (de) * | 2004-03-26 | 2008-01-31 | Lavision Biotec Gmbh | Verfahren zum Auslesen durch streifenweises Abtasten von flächigen Objekten mit Substanzen, die Fluoreszenzstrahlung abgeben |
US20050244953A1 (en) * | 2004-04-30 | 2005-11-03 | Kimberly-Clark Worldwide, Inc. | Techniques for controlling the optical properties of assay devices |
US7815854B2 (en) * | 2004-04-30 | 2010-10-19 | Kimberly-Clark Worldwide, Inc. | Electroluminescent illumination source for optical detection systems |
US20060019265A1 (en) * | 2004-04-30 | 2006-01-26 | Kimberly-Clark Worldwide, Inc. | Transmission-based luminescent detection systems |
US7796266B2 (en) * | 2004-04-30 | 2010-09-14 | Kimberly-Clark Worldwide, Inc. | Optical detection system using electromagnetic radiation to detect presence or quantity of analyte |
JP4500612B2 (ja) | 2004-07-09 | 2010-07-14 | 横河電機株式会社 | バイオチップ読取装置 |
WO2006009077A1 (ja) * | 2004-07-16 | 2006-01-26 | Fujifilm Corporation | 蛍光検出方法 |
JP2008506959A (ja) * | 2004-07-21 | 2008-03-06 | チェングドゥ クアチャング メディカル インダストリアル リミテッド | マルチリアクタ・分析チップのテスト方法、該分析チップ及びテスト装置 |
US20070121113A1 (en) * | 2004-12-22 | 2007-05-31 | Cohen David S | Transmission-based optical detection systems |
ES2285578T3 (es) * | 2005-01-18 | 2007-11-16 | F. Hoffmann-La Roche Ag | Visualizacion de señales de fluorescencia utilizando telecentricidad. |
JP5203951B2 (ja) * | 2005-10-14 | 2013-06-05 | ザ ジェネラル ホスピタル コーポレイション | スペクトル及び周波数符号化蛍光画像形成 |
JP2009526993A (ja) * | 2006-02-15 | 2009-07-23 | リ−コール インコーポレーティッド | 分子撮像のための蛍光フィルタリングシステムおよび方法 |
DE102006023945A1 (de) * | 2006-05-18 | 2007-11-22 | Jenoptik Instruments Gmbh | Verfahren und optisches Modul zum Auslesen von Biochips |
RU2009116936A (ru) * | 2006-10-05 | 2010-11-10 | Конинклейке Филипс Электроникс Н.В. (Nl) | Способы и системы детектирования при фронтальном облучении |
JP5265558B2 (ja) * | 2006-11-03 | 2013-08-14 | テューダー アルヴィンテ | 試料評価方法および装置 |
JP2010032400A (ja) * | 2008-07-30 | 2010-02-12 | Yokogawa Electric Corp | バイオチップ読取装置 |
US8449842B2 (en) * | 2009-03-19 | 2013-05-28 | Thermo Scientific Portable Analytical Instruments Inc. | Molecular reader |
JP2011038922A (ja) * | 2009-08-12 | 2011-02-24 | Sony Corp | 光検出用チップおよび該光検出用チップを用いた光検出装置 |
US9068916B2 (en) * | 2010-03-15 | 2015-06-30 | Bio-Rad Laboratories, Inc. | Microassembled imaging flow cytometer |
FR2968402B1 (fr) * | 2010-12-07 | 2013-02-15 | Ecole Polytech | Systeme et procede d'imagerie multitechniques pour l'analyse chimique, biologique ou biochimique d'un echantillon. |
KR101316568B1 (ko) * | 2012-03-14 | 2013-10-15 | 한국식품연구원 | 테라파를 이용한 고 분해능 물체 검사 장치 |
JP2014095594A (ja) * | 2012-11-08 | 2014-05-22 | Yokogawa Electric Corp | 分光装置および分光用光源 |
US8785885B1 (en) * | 2013-01-30 | 2014-07-22 | Omnivision Technologies, Inc. | Fluorescence imaging module |
JP6331191B2 (ja) * | 2013-09-20 | 2018-05-30 | 国立大学法人九州大学 | 光測定装置、光測定方法、フィルタ部材及びフィルタ部材を生産する方法 |
US9541750B2 (en) | 2014-06-23 | 2017-01-10 | Li-Cor, Inc. | Telecentric, wide-field fluorescence scanning systems and methods |
US9482624B2 (en) * | 2014-10-29 | 2016-11-01 | SUNMOON UNIVERSITY Industry-University Cooperation | Apparatus for inspecting |
KR102350656B1 (ko) | 2017-02-17 | 2022-01-12 | (주)옵토레인 | 면역진단 카트리지 |
CN106990519B (zh) * | 2017-05-12 | 2024-09-24 | 中国科学院苏州生物医学工程技术研究所 | 结构光照明显微成像系统 |
CN107525937A (zh) * | 2017-08-25 | 2017-12-29 | 苏州优函信息科技有限公司 | 基于上转换发光标记物、蛋白芯片及检测方法 |
CN109164080B (zh) * | 2018-09-29 | 2024-06-14 | 江苏瑞明生物科技有限公司 | 适用于细胞水平无损荧光检测光谱仪 |
JP7545259B2 (ja) | 2020-08-07 | 2024-09-04 | 浜松ホトニクス株式会社 | 光学素子、光検出装置、及び蛍光検出装置 |
CN114137195B (zh) * | 2021-12-03 | 2023-12-12 | 南京大学 | 一种基于图像拍摄分析的高通量生化检测系统及其方法 |
Family Cites Families (46)
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JPS523585B2 (de) * | 1972-07-23 | 1977-01-28 | ||
JPS5419263B2 (de) * | 1973-10-17 | 1979-07-13 | ||
JPS55144530A (en) * | 1979-04-27 | 1980-11-11 | Susumu Yagyu | Two-wavelength photometer for measuring microplate |
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JPS6082865A (ja) * | 1983-10-12 | 1985-05-11 | Toshiba Corp | 自動化学分析装置 |
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JPS6166950A (ja) * | 1984-09-11 | 1986-04-05 | Nippon Tectron Co Ltd | 血液自動分析装置のデ−タ処理装置 |
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FR2903930B3 (fr) * | 2006-07-21 | 2008-10-17 | James Dagan | Vrille |
-
2002
- 2002-02-08 JP JP2002031668A patent/JP3741051B2/ja not_active Expired - Lifetime
- 2002-03-18 US US10/098,534 patent/US6867860B2/en not_active Expired - Lifetime
- 2002-03-21 EP EP02006377A patent/EP1256795A3/de not_active Withdrawn
- 2002-03-21 DE DE60227297T patent/DE60227297D1/de not_active Expired - Lifetime
- 2002-03-21 EP EP06100549A patent/EP1650554B1/de not_active Expired - Lifetime
- 2002-03-21 EP EP06100547A patent/EP1653220A3/de not_active Withdrawn
- 2002-03-21 EP EP06100542A patent/EP1650552A3/de not_active Withdrawn
- 2002-03-21 EP EP06100532.8A patent/EP1650551B1/de not_active Expired - Lifetime
- 2002-03-21 EP EP06100548A patent/EP1650553B1/de not_active Expired - Lifetime
- 2002-03-21 DE DE60228769T patent/DE60228769D1/de not_active Expired - Lifetime
-
2003
- 2003-09-22 US US10/664,964 patent/US6888630B2/en not_active Expired - Fee Related
- 2003-09-22 US US10/664,908 patent/US6873410B2/en not_active Expired - Lifetime
- 2003-09-22 US US10/664,965 patent/US6864976B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP3741051B2 (ja) | 2006-02-01 |
EP1653220A3 (de) | 2006-08-30 |
JP2003028799A (ja) | 2003-01-29 |
US20040066511A1 (en) | 2004-04-08 |
US6888630B2 (en) | 2005-05-03 |
EP1650551A2 (de) | 2006-04-26 |
US20020167662A1 (en) | 2002-11-14 |
EP1653220A2 (de) | 2006-05-03 |
US6873410B2 (en) | 2005-03-29 |
EP1650553A8 (de) | 2006-07-05 |
EP1650551B1 (de) | 2014-01-08 |
EP1650552A3 (de) | 2006-08-23 |
US6867860B2 (en) | 2005-03-15 |
EP1650553A3 (de) | 2006-08-23 |
EP1650551A3 (de) | 2006-05-17 |
EP1256795A2 (de) | 2002-11-13 |
EP1256795A3 (de) | 2006-03-29 |
EP1650554B1 (de) | 2008-06-25 |
US20040056098A1 (en) | 2004-03-25 |
US6864976B2 (en) | 2005-03-08 |
US20040057048A1 (en) | 2004-03-25 |
EP1650552A2 (de) | 2006-04-26 |
EP1650554A3 (de) | 2006-08-30 |
DE60228769D1 (de) | 2008-10-16 |
EP1650553A2 (de) | 2006-04-26 |
EP1650554A2 (de) | 2006-04-26 |
EP1650553B1 (de) | 2008-09-03 |
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