DE60212464D1 - Herstellung von tabletten von pharmazeutisch aktiven substanzen mit ungünstigen tablettierungseigenschaften mit einer mikrokristalline zellulose enthaltenden granulierflüssigkeit - Google Patents
Herstellung von tabletten von pharmazeutisch aktiven substanzen mit ungünstigen tablettierungseigenschaften mit einer mikrokristalline zellulose enthaltenden granulierflüssigkeitInfo
- Publication number
- DE60212464D1 DE60212464D1 DE60212464T DE60212464T DE60212464D1 DE 60212464 D1 DE60212464 D1 DE 60212464D1 DE 60212464 T DE60212464 T DE 60212464T DE 60212464 T DE60212464 T DE 60212464T DE 60212464 D1 DE60212464 D1 DE 60212464D1
- Authority
- DE
- Germany
- Prior art keywords
- microcrystalline cellulose
- tablets
- preparation
- pharmaceutically active
- invalid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229920000168 Microcrystalline cellulose Polymers 0.000 title abstract 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 title abstract 2
- 239000008108 microcrystalline cellulose Substances 0.000 title abstract 2
- 229940016286 microcrystalline cellulose Drugs 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- 239000012530 fluid Substances 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/HU2002/000035 WO2003092658A1 (en) | 2002-04-29 | 2002-04-29 | A process for the preparation of tablets from pharmaceutically active substances having unfavourable tabletting properties with a granulating liquid comprising microcrystalline cellulose |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60212464D1 true DE60212464D1 (de) | 2006-07-27 |
DE60212464T2 DE60212464T2 (de) | 2007-01-11 |
Family
ID=29287270
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60212464T Expired - Fee Related DE60212464T2 (de) | 2002-04-29 | 2002-04-29 | Herstellung von tabletten von pharmazeutisch aktiven substanzen mit ungünstigen tablettierungseigenschaften mit einer mikrokristalline zellulose enthaltenden granulierflüssigkeit |
Country Status (14)
Country | Link |
---|---|
US (1) | US20050163836A1 (de) |
EP (1) | EP1501484B2 (de) |
AT (1) | ATE329582T1 (de) |
AU (1) | AU2002258002A1 (de) |
CZ (1) | CZ296100B6 (de) |
DE (1) | DE60212464T2 (de) |
DK (1) | DK1501484T3 (de) |
EA (1) | EA006008B1 (de) |
ES (1) | ES2266496T3 (de) |
HK (1) | HK1073263A1 (de) |
PT (1) | PT1501484E (de) |
SK (1) | SK50232004A3 (de) |
UA (1) | UA75831C2 (de) |
WO (1) | WO2003092658A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9720061D0 (en) | 1997-09-19 | 1997-11-19 | Crosfield Joseph & Sons | Metal compounds as phosphate binders |
US20050163846A1 (en) * | 2001-11-21 | 2005-07-28 | Eisai Co., Ltd. | Preparation composition containing acid-unstable physiologically active compound, and process for producing same |
HUP0301537A3 (en) * | 2003-06-03 | 2005-07-28 | Egis Gyogyszergyar Nyilvanosan | Deramcyclane fumarate tablets and process for producing them |
CN1893956A (zh) * | 2003-07-25 | 2007-01-10 | 沃纳奇尔科特公司 | 多西环素金属络合物固体剂型 |
US20080095839A1 (en) * | 2004-03-26 | 2008-04-24 | Eisai R&D Management Co., Ltd. | Controlled-Release Pharmaceutical Composition and Method for Producing the Same |
EP1930030A1 (de) * | 2005-09-29 | 2008-06-11 | Eisai R&D Management Co., Ltd. | Puls-präparat mit verbesserten zerfallseigenschaften in vivo |
MY157620A (en) | 2006-01-31 | 2016-06-30 | Cytochroma Dev Inc | A granular material of a solid water-soluble mixed metal compound capable of binding phosphate |
WO2008062320A2 (en) | 2006-10-06 | 2008-05-29 | Eisai R&D Management Co., Ltd | Extended release formulations of a proton pump inhibitor |
GB0714670D0 (en) | 2007-07-27 | 2007-09-05 | Ineos Healthcare Ltd | Use |
GB0720220D0 (en) | 2007-10-16 | 2007-11-28 | Ineos Healthcare Ltd | Compound |
GB0913525D0 (en) | 2009-08-03 | 2009-09-16 | Ineos Healthcare Ltd | Method |
GB201001779D0 (en) | 2010-02-04 | 2010-03-24 | Ineos Healthcare Ltd | Composition |
US20130338121A1 (en) * | 2011-03-01 | 2013-12-19 | Le Tien Canh | Two speed monolithic system for controlled release of drugs |
EP3157516A4 (de) | 2014-06-22 | 2017-12-13 | Dexcel Pharma Technologies Ltd. | Pharmazeutische zusammensetzungen mit eisencitrat und verfahren zur herstellung davon |
RU2657424C1 (ru) * | 2017-02-27 | 2018-06-13 | Павел Владимирович Алексенко | Способ производства таблеток |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3146168A (en) † | 1962-04-10 | 1964-08-25 | Fmc Corp | Manufacture of pharmaceutical preparations containing cellulose crystallite aggregates |
US4543332A (en) * | 1982-03-29 | 1985-09-24 | Miles Laboratories, Inc. | Method for the preparation of spherical microorganism cell aggregates |
US5073380A (en) * | 1987-07-27 | 1991-12-17 | Mcneil-Ppc, Inc. | Oral sustained release pharmaceutical formulation and process |
US4911921A (en) † | 1989-02-02 | 1990-03-27 | Mallinckrodt, Inc. | High ibuprofen content granulations |
DE69227240T2 (de) † | 1991-01-16 | 1999-04-08 | Fmc Corp., Philadelphia, Pa. | Träger für wirkstoffe und damit hergestellte feste darreichungsformen |
HU214588B (hu) † | 1994-07-01 | 1998-04-28 | EGIS Gyógyszergyár Rt. | Eljárás bicikloheptán-származékot tartalmazó, CCK-rendszer gátló hatású gyógyászati készítmények előállítására |
JPH10139659A (ja) * | 1996-09-10 | 1998-05-26 | Freunt Ind Co Ltd | 球形粒子群、その製造方法及びそれを用いた球形粒子製剤 |
HU226061B1 (en) * | 1996-10-17 | 2008-04-28 | Egis Gyogyszergyar Nyilvanosan | 1,7,7-trimethyl-bicyclo[2.2.1]heptane derivative, pharmaceutical compositions containing the same and process for their preparation |
AU1970797A (en) * | 1997-02-25 | 1998-09-09 | Procter & Gamble Company, The | Wet granulating method |
US6852337B2 (en) * | 1998-04-09 | 2005-02-08 | Roche Diagnostics Gmbh | Carvedilol-galenics |
-
2002
- 2002-04-29 WO PCT/HU2002/000035 patent/WO2003092658A1/en not_active Application Discontinuation
- 2002-04-29 ES ES02727807T patent/ES2266496T3/es not_active Expired - Lifetime
- 2002-04-29 US US10/512,957 patent/US20050163836A1/en not_active Abandoned
- 2002-04-29 DE DE60212464T patent/DE60212464T2/de not_active Expired - Fee Related
- 2002-04-29 SK SK5023-2004A patent/SK50232004A3/sk unknown
- 2002-04-29 DK DK02727807T patent/DK1501484T3/da active
- 2002-04-29 CZ CZ20041145A patent/CZ296100B6/cs not_active IP Right Cessation
- 2002-04-29 EP EP02727807A patent/EP1501484B2/de not_active Expired - Lifetime
- 2002-04-29 UA UA20041109803A patent/UA75831C2/uk unknown
- 2002-04-29 EA EA200401418A patent/EA006008B1/ru not_active IP Right Cessation
- 2002-04-29 AU AU2002258002A patent/AU2002258002A1/en not_active Abandoned
- 2002-04-29 AT AT02727807T patent/ATE329582T1/de not_active IP Right Cessation
- 2002-04-29 PT PT02727807T patent/PT1501484E/pt unknown
-
2005
- 2005-07-28 HK HK05106494A patent/HK1073263A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EA006008B1 (ru) | 2005-08-25 |
DE60212464T2 (de) | 2007-01-11 |
EP1501484B1 (de) | 2006-06-14 |
CZ296100B6 (cs) | 2006-01-11 |
EP1501484A1 (de) | 2005-02-02 |
ATE329582T1 (de) | 2006-07-15 |
EP1501484B2 (de) | 2010-07-07 |
AU2002258002A1 (en) | 2003-11-17 |
PT1501484E (pt) | 2006-10-31 |
DK1501484T3 (da) | 2006-10-23 |
US20050163836A1 (en) | 2005-07-28 |
EA200401418A1 (ru) | 2005-04-28 |
WO2003092658A1 (en) | 2003-11-13 |
HK1073263A1 (en) | 2005-09-30 |
UA75831C2 (en) | 2006-05-15 |
ES2266496T3 (es) | 2007-03-01 |
CZ20041145A3 (cs) | 2005-03-16 |
SK50232004A3 (sk) | 2005-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8339 | Ceased/non-payment of the annual fee |