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DE60208385D1 - Antineoplasische kombinationspräparate - Google Patents

Antineoplasische kombinationspräparate

Info

Publication number
DE60208385D1
DE60208385D1 DE60208385T DE60208385T DE60208385D1 DE 60208385 D1 DE60208385 D1 DE 60208385D1 DE 60208385 T DE60208385 T DE 60208385T DE 60208385 T DE60208385 T DE 60208385T DE 60208385 D1 DE60208385 D1 DE 60208385D1
Authority
DE
Germany
Prior art keywords
antineoplasic
combination preparations
preparations
combination
antineoplasic combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60208385T
Other languages
English (en)
Other versions
DE60208385T2 (de
Inventor
Krishna Rabindran
J Gibbons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of DE60208385D1 publication Critical patent/DE60208385D1/de
Application granted granted Critical
Publication of DE60208385T2 publication Critical patent/DE60208385T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and unsaturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60208385T 2001-08-07 2002-08-06 Antineoplastische kombinationspräparate Expired - Fee Related DE60208385T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31064601P 2001-08-07 2001-08-07
US310646P 2001-08-07
PCT/US2002/024841 WO2003020266A1 (en) 2001-08-07 2002-08-06 Antineoplastic combinations

Publications (2)

Publication Number Publication Date
DE60208385D1 true DE60208385D1 (de) 2006-02-02
DE60208385T2 DE60208385T2 (de) 2006-08-03

Family

ID=23203475

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60208385T Expired - Fee Related DE60208385T2 (de) 2001-08-07 2002-08-06 Antineoplastische kombinationspräparate

Country Status (26)

Country Link
US (4) US6617333B2 (de)
EP (2) EP1414438B1 (de)
JP (2) JP2005505549A (de)
KR (1) KR20040029406A (de)
CN (3) CN1326523C (de)
AR (2) AR036250A1 (de)
AT (1) ATE314069T1 (de)
AU (2) AU2002330994B2 (de)
BR (1) BR0211769A (de)
CA (1) CA2455126A1 (de)
CY (1) CY1104983T1 (de)
DE (1) DE60208385T2 (de)
DK (1) DK1414438T3 (de)
EA (2) EA011098B1 (de)
ES (1) ES2252512T3 (de)
HU (1) HUP0401089A3 (de)
IL (2) IL159859A0 (de)
MX (1) MXPA04001118A (de)
NO (2) NO325503B1 (de)
NZ (3) NZ542272A (de)
PL (1) PL368303A1 (de)
SG (1) SG170612A1 (de)
TW (2) TWI300351B (de)
UA (1) UA77200C2 (de)
WO (1) WO2003020266A1 (de)
ZA (1) ZA200401801B (de)

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CL2004000016A1 (es) 2003-01-21 2005-04-15 Wyeth Corp Compuesto derivado de cloruro de 4-amino-2-butenoilo o una sal farmaceuticamente aceptable del mismo; procedimiento para preparar dicho compuesto, util como intermediario en la sintesis de compuestos inhibidores de proteina quinasa tirosina.

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TWI300351B (en) 2008-09-01
WO2003020266A1 (en) 2003-03-13
EA200501251A1 (ru) 2008-12-30
AR036250A1 (es) 2004-08-25
TW200626526A (en) 2006-08-01
EP1414438B1 (de) 2005-12-28
NZ542272A (en) 2007-12-21
USRE41084E1 (en) 2010-01-19
EA200400284A1 (ru) 2004-06-24
CY1104983T1 (el) 2010-03-03
NZ530847A (en) 2006-02-24
KR20040029406A (ko) 2004-04-06
NO20073801L (no) 2004-02-06
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JP2005505549A (ja) 2005-02-24
AU2006233165A1 (en) 2006-11-09
EP1414438A1 (de) 2004-05-06
BR0211769A (pt) 2004-07-27
CN1326523C (zh) 2007-07-18
USRE40418E1 (en) 2008-07-01
ZA200401801B (en) 2005-06-06
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AU2006233165B2 (en) 2009-12-24
AU2002330994B2 (en) 2007-10-04
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UA77200C2 (en) 2006-11-15
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