DE60205888D1 - Das citrat-salz des 5,8,14,-triazatetracyclo(10.3.1.02,11.04,9)-hexadeca-2(11),3,5,7,9-pentaens - Google Patents

Das citrat-salz des 5,8,14,-triazatetracyclo(10.3.1.02,11.04,9)-hexadeca-2(11),3,5,7,9-pentaens

Info

Publication number: DE60205888D1
Authority: DE; Germany
Prior art keywords: reacyclo; triazate; pentaene; hexadeca; citrate salt
Prior art date: 2001-05-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60205888T

Other languages

English (en)

Other versions

DE60205888T2 (de

Inventor

James Johnson

Robert Rose

Theophilus Wint

Robert Williams

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Products Inc

Original Assignee

Pfizer Products Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-14

Filing date

2002-04-26

Publication date

2005-10-06

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23117854&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60205888(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-04-26 Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc

2005-10-06 Publication of DE60205888D1 publication Critical patent/DE60205888D1/de

2006-07-06 Application granted granted Critical

2006-07-06 Publication of DE60205888T2 publication Critical patent/DE60205888T2/de

2022-04-27 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Diabetes (AREA)
Dermatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Psychology (AREA)
Virology (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Communicable Diseases (AREA)
Anesthesiology (AREA)
Hematology (AREA)
Oncology (AREA)
AIDS & HIV (AREA)
Rheumatology (AREA)
Obesity (AREA)

DE60205888T 2001-05-14 2002-04-26 Das citratsalz von 5,8,14-triazatetracyclo(10.3.1.02,11.04.9)-hexadeca-2(11),3,5,7,9-pentaen Expired - Fee Related DE60205888T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US29086301P	2001-05-14	2001-05-14
US290863P		2001-05-14
PCT/IB2002/001450 WO2002092597A1 (en)	2001-05-14	2002-04-26	The citrate salt of 5, 8, 14-triazatetracyclo(10.3.1.0?2,11.04.9¿)-hexadeca-2.(11),3,5,7,9-pentaene and pharmaceutical compositions thereof

Publications (2)

Publication Number	Publication Date
DE60205888D1 true DE60205888D1 (de)	2005-10-06
DE60205888T2 DE60205888T2 (de)	2006-07-06

Family

ID=23117854

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60205888T Expired - Fee Related DE60205888T2 (de)	2001-05-14	2002-04-26	Das citratsalz von 5,8,14-triazatetracyclo(10.3.1.02,11.04.9)-hexadeca-2(11),3,5,7,9-pentaen

Country Status (37)

Country	Link
US (1)	US6787549B2 (de)
EP (1)	EP1390366B1 (de)
JP (1)	JP4137645B2 (de)
KR (1)	KR20040008175A (de)
CN (1)	CN1509288A (de)
AP (1)	AP1429A (de)
AR (1)	AR035889A1 (de)
AT (1)	ATE303386T1 (de)
BG (1)	BG108344A (de)
CA (1)	CA2446988A1 (de)
CZ (1)	CZ20032917A3 (de)
DE (1)	DE60205888T2 (de)
DO (1)	DOP2002000390A (de)
DZ (1)	DZ3503A1 (de)
EA (1)	EA005529B1 (de)
EE (1)	EE200300557A (de)
ES (1)	ES2245731T3 (de)
GT (1)	GT200200081A (de)
HR (1)	HRP20030911A2 (de)
HU (1)	HUP0304085A3 (de)
IL (1)	IL157874A0 (de)
IS (1)	IS6956A (de)
MA (1)	MA27021A1 (de)
MX (1)	MXPA03010365A (de)
MY (1)	MY134123A (de)
NO (1)	NO20035035L (de)
NZ (1)	NZ528209A (de)
OA (1)	OA12600A (de)
PA (1)	PA8545001A1 (de)
PE (1)	PE20021095A1 (de)
PL (1)	PL366774A1 (de)
SK (1)	SK13372003A3 (de)
TN (1)	TNSN03112A1 (de)
UA (1)	UA73421C2 (de)
UY (1)	UY27287A1 (de)
WO (1)	WO2002092597A1 (de)
ZA (1)	ZA200307234B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9816186B1 (pt) *	1997-12-31	2009-01-13		processo para preparar compostos azapolicÍclico condensados com arila.
KR100892517B1 (ko) *	2001-11-30	2009-04-10	화이자 프로덕츠 인크.	5,8,14-트리아자테트라시클로[10.3.1.0(2,11).0(4,9)]-헥사데카-2(11)3,5,7,9-펜타엔의 약학 조성물
CA2525874C (en) *	2003-05-20	2007-11-27	Pfizer Products Inc.	Pharmaceutical compositions of varenicline
US20050043407A1 (en) *	2003-08-22	2005-02-24	Pfizer Inc	Pharmaceutical composition for the prevention and treatment of addiction in a mammal
WO2008060487A2 (en) *	2006-11-09	2008-05-22	Pfizer Products Inc.	Polymorphs of nicotinic intermediates
US8440825B2 (en)	2008-03-06	2013-05-14	Medichem S.A.	Fumaric acid salt of varenicline
EP2268639A2 (de)	2008-05-22	2011-01-05	Teva Pharmaceutical Industries Ltd.	Vareniclin-tosylat, ein zwischenprodukt bei der herstellung von vareniclin-l-tartrat
US20090318460A1 (en) *	2008-05-26	2009-12-24	Glenmark	Amorphous varenicline tartrate and process for the preparation thereof
WO2009155403A2 (en) *	2008-06-19	2009-12-23	Teva Pharmaceutical Industries Ltd.	Processes for the preparation of varenicline and intermediates thereof
US20100010221A1 (en) *	2008-07-10	2010-01-14	Revital Lifshitz-Liron	Processes for purifying varenicline l-tartrate salt and preparing crystalline forms of varenicline l-tartrate salt
AU2009325147B2 (en) *	2008-12-11	2014-08-14	Cti Biopharma Corp.	11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6)1(8,12)] heptacosa-1(25),2(26),3,5,8,10,12(27)j16,21,23-decaene citrate salt
US20100189790A1 (en)	2009-01-23	2010-07-29	Teva Pharmaceutical Industries, Ltd.	Delayed release rasagiline formulation
CA2801842A1 (en)	2009-06-10	2010-12-16	Actavis Group Ptc Ehf	Amorphous varenicline tartrate co-precipitates
US8178537B2 (en)	2009-06-22	2012-05-15	Teva Pharmaceutical Industries Ltd.	Solid state forms of varenicline salts and processes for preparation thereof
WO2011140431A1 (en)	2010-05-06	2011-11-10	Teva Pharmaceutical Industries Ltd.	Varenicline salts and crystal forms thereof
CN104334561B (zh)	2012-04-13	2016-06-22	连云港金康和信药业有限公司	化合物jk12a及其制备
WO2018154395A2 (en)	2018-06-11	2018-08-30	Alvogen Malta Operations (Row) Ltd	Controlled release pharmaceutical composition of varenicline
EP3756653A1 (de)	2019-06-28	2020-12-30	Alfred E. Tiefenbacher (GmbH & Co. KG)	Mikropartikuläres vareniclin-citrat
WO2021188563A1 (en) *	2020-03-16	2021-09-23	Chengdu Scimount Pharmatech Co., Ltd.	5-ht3 receptor modulator, the crystalline form, methods of making, and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9816186B1 (pt) *	1997-12-31	2009-01-13		processo para preparar compostos azapolicÍclico condensados com arila.
IL137937A0 (en) *	1999-08-27	2001-10-31	Pfizer Prod Inc	A pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal

2002
- 2002-04-26 CZ CZ20032917A patent/CZ20032917A3/cs unknown
- 2002-04-26 AT AT02724553T patent/ATE303386T1/de not_active IP Right Cessation
- 2002-04-26 HU HU0304085A patent/HUP0304085A3/hu unknown
- 2002-04-26 CN CNA028099117A patent/CN1509288A/zh active Pending
- 2002-04-26 PL PL02366774A patent/PL366774A1/xx not_active Application Discontinuation
- 2002-04-26 NZ NZ528209A patent/NZ528209A/en unknown
- 2002-04-26 UA UA20031110265A patent/UA73421C2/uk unknown
- 2002-04-26 EP EP02724553A patent/EP1390366B1/de not_active Expired - Lifetime
- 2002-04-26 EE EEP200300557A patent/EE200300557A/xx unknown
- 2002-04-26 MX MXPA03010365A patent/MXPA03010365A/es active IP Right Grant
- 2002-04-26 SK SK1337-2003A patent/SK13372003A3/sk unknown
- 2002-04-26 KR KR10-2003-7014752A patent/KR20040008175A/ko not_active Ceased
- 2002-04-26 DO DO2002000390A patent/DOP2002000390A/es unknown
- 2002-04-26 JP JP2002589481A patent/JP4137645B2/ja not_active Expired - Fee Related
- 2002-04-26 DE DE60205888T patent/DE60205888T2/de not_active Expired - Fee Related
- 2002-04-26 IL IL15787402A patent/IL157874A0/xx unknown
- 2002-04-26 DZ DZ023503A patent/DZ3503A1/fr active
- 2002-04-26 WO PCT/IB2002/001450 patent/WO2002092597A1/en active IP Right Grant
- 2002-04-26 CA CA002446988A patent/CA2446988A1/en not_active Abandoned
- 2002-04-26 OA OA1200300290A patent/OA12600A/en unknown
- 2002-04-26 EA EA200301120A patent/EA005529B1/ru not_active IP Right Cessation
- 2002-04-26 ES ES02724553T patent/ES2245731T3/es not_active Expired - Lifetime
- 2002-05-06 US US10/139,449 patent/US6787549B2/en not_active Expired - Fee Related
- 2002-05-09 AP APAP/P/2002/002522A patent/AP1429A/en active
- 2002-05-09 GT GT200200081A patent/GT200200081A/es unknown
- 2002-05-10 PE PE2002000392A patent/PE20021095A1/es not_active Application Discontinuation
- 2002-05-13 UY UY27287A patent/UY27287A1/es not_active Application Discontinuation
- 2002-05-13 MY MYPI20021725A patent/MY134123A/en unknown
- 2002-05-13 AR ARP020101735A patent/AR035889A1/es unknown
- 2002-05-14 PA PA20028545001A patent/PA8545001A1/es unknown
2003
- 2003-07-08 TN TNPCT/IB2002/001450A patent/TNSN03112A1/fr unknown
- 2003-09-15 IS IS6956A patent/IS6956A/is unknown
- 2003-09-16 ZA ZA200307234A patent/ZA200307234B/en unknown
- 2003-11-10 HR HR20030911A patent/HRP20030911A2/xx not_active Application Discontinuation
- 2003-11-10 MA MA27390A patent/MA27021A1/fr unknown
- 2003-11-11 BG BG108344A patent/BG108344A/bg unknown
- 2003-11-13 NO NO20035035A patent/NO20035035L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL157874A0 (en)	2004-03-28
SK13372003A3 (sk)	2004-08-03
OA12600A (en)	2006-06-09
AP2002002522A0 (en)	2002-06-30
ES2245731T3 (es)	2006-01-16
JP2004529186A (ja)	2004-09-24
MXPA03010365A (es)	2004-03-16
BG108344A (bg)	2004-12-30
EA005529B1 (ru)	2005-04-28
DE60205888T2 (de)	2006-07-06
PE20021095A1 (es)	2002-12-14
EP1390366B1 (de)	2005-08-31
DOP2002000390A (es)	2003-03-15
UY27287A1 (es)	2003-02-28
MY134123A (en)	2007-11-30
EP1390366A1 (de)	2004-02-25
CN1509288A (zh)	2004-06-30
GT200200081A (es)	2003-04-22
DZ3503A1 (de)	2002-11-21
EA200301120A1 (ru)	2004-02-26
ZA200307234B (en)	2004-09-16
ATE303386T1 (de)	2005-09-15
EE200300557A (et)	2004-04-15
MA27021A1 (fr)	2004-12-20
UA73421C2 (en)	2005-07-15
KR20040008175A (ko)	2004-01-28
US20030149091A1 (en)	2003-08-07
CA2446988A1 (en)	2002-11-21
HUP0304085A3 (en)	2005-09-28
NO20035035D0 (no)	2003-11-13
TNSN03112A1 (fr)	2005-12-23
WO2002092597A1 (en)	2002-11-21
PL366774A1 (en)	2005-02-07
IS6956A (is)	2003-09-15
NZ528209A (en)	2004-09-24
CZ20032917A3 (cs)	2004-07-14
US6787549B2 (en)	2004-09-07
JP4137645B2 (ja)	2008-08-20
HUP0304085A2 (en)	2004-04-28
AR035889A1 (es)	2004-07-21
NO20035035L (no)	2003-11-13
AP1429A (en)	2005-06-13
HRP20030911A2 (en)	2004-02-29
PA8545001A1 (es)	2003-09-05

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