[go: up one dir, main page]

DE60204352D1 - Haut/haar-äquivalent mit rekonstruierten papillen - Google Patents

Haut/haar-äquivalent mit rekonstruierten papillen

Info

Publication number
DE60204352D1
DE60204352D1 DE60204352T DE60204352T DE60204352D1 DE 60204352 D1 DE60204352 D1 DE 60204352D1 DE 60204352 T DE60204352 T DE 60204352T DE 60204352 T DE60204352 T DE 60204352T DE 60204352 D1 DE60204352 D1 DE 60204352D1
Authority
DE
Germany
Prior art keywords
reconstructed
skin
papillas
hair equivalent
hair
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60204352T
Other languages
English (en)
Other versions
DE60204352T2 (de
Inventor
Kordula Schlotmann
Thomas Gassenmeier
Ralf Paus
Melanie Giesen
Dirk Petersohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel AG and Co KGaA
Cutech SRL
Original Assignee
Henkel AG and Co KGaA
Cutech SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7710083&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60204352(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Henkel AG and Co KGaA, Cutech SRL filed Critical Henkel AG and Co KGaA
Priority to DE60204352T priority Critical patent/DE60204352T2/de
Publication of DE60204352D1 publication Critical patent/DE60204352D1/de
Application granted granted Critical
Publication of DE60204352T2 publication Critical patent/DE60204352T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0627—Hair cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/18—Materials or treatment for tissue regeneration for hair reconstruction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60204352T 2001-12-19 2002-12-13 Haut/haar-äquivalent mit rekonstruierten papillen Expired - Lifetime DE60204352T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE60204352T DE60204352T2 (de) 2001-12-19 2002-12-13 Haut/haar-äquivalent mit rekonstruierten papillen

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10162814A DE10162814B4 (de) 2001-12-19 2001-12-19 Rekonstruiertes Haarfollikelmodell
DE10162814 2001-12-19
DE60204352T DE60204352T2 (de) 2001-12-19 2002-12-13 Haut/haar-äquivalent mit rekonstruierten papillen
PCT/EP2002/014212 WO2003051419A1 (en) 2001-12-19 2002-12-13 Skin/hair equivalent with reconstructed papillae

Publications (2)

Publication Number Publication Date
DE60204352D1 true DE60204352D1 (de) 2005-06-30
DE60204352T2 DE60204352T2 (de) 2006-01-26

Family

ID=7710083

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10162814A Expired - Fee Related DE10162814B4 (de) 2001-12-19 2001-12-19 Rekonstruiertes Haarfollikelmodell
DE60204352T Expired - Lifetime DE60204352T2 (de) 2001-12-19 2002-12-13 Haut/haar-äquivalent mit rekonstruierten papillen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE10162814A Expired - Fee Related DE10162814B4 (de) 2001-12-19 2001-12-19 Rekonstruiertes Haarfollikelmodell

Country Status (7)

Country Link
EP (1) EP1455854B1 (de)
JP (1) JP2005525088A (de)
AT (1) ATE296124T1 (de)
AU (1) AU2002366280A1 (de)
DE (2) DE10162814B4 (de)
ES (1) ES2243801T3 (de)
WO (1) WO2003051419A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101156797B1 (ko) * 2003-10-06 2012-06-18 가부시키가이샤 시세이도 재생된 모포를 담지하는 동물
WO2005120575A1 (ja) * 2004-06-14 2005-12-22 Shiseido Company, Ltd. 毛包形成抑制能を有する遺伝子の抑制又は毛包形成誘導能を有する遺伝子の活性化による毛包再生方法
KR100616752B1 (ko) 2004-11-29 2006-08-31 박정극 모낭 유도 능력이 있는 모유두 조직의 제조방법
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
GB0605450D0 (en) * 2006-03-17 2006-04-26 Intercytex Ltd Cell co-culture
FR2903702B1 (fr) 2006-07-13 2012-10-19 Oreal Equivalent d'epiderme capable de se pigmenter obtenu a partir de cellules de la matrice, procede de preparation et utilisation
DE102006043767A1 (de) 2006-09-13 2008-03-27 Henkel Kgaa Extrakt aus Apium graveleons zur Stimulierung des Haarwuchses
GB2442271B (en) * 2006-09-27 2011-06-15 Denis Eon Solomon An in vitro human skin assay protocol which directly uses the natural cellular interactions between un-manipulated autologous human epidermal and dermal cells
JP5097387B2 (ja) * 2006-11-16 2012-12-12 ライオン株式会社 人工皮膚
DE102007032393A1 (de) 2007-07-10 2009-01-29 Henkel Ag & Co. Kgaa Advanced Glycation Endproducts als Wirkstoffe
DE102007048409A1 (de) * 2007-10-09 2009-04-16 Carl Zeiss Microimaging Gmbh Verfahren zum Positionieren von biologischen Proben in einer mikroskopischen Anordnung
EP2105499A1 (de) * 2008-03-28 2009-09-30 Technische Universität Berlin Verfahren zum Herstellen von Novo Papillae und Haarmikrofollikeln und ihre Verwendung bei In-vitro-Tests und in-vivo-Implantationen
DE102009043486A1 (de) 2009-09-30 2010-07-01 Henkel Ag & Co. Kgaa Verwendung von Wirkstoffen, erhältlich aus Pflanzen, zur Verhinderung und/oder Verminderung der Auswirkungen von psychoemotionalem Stress auf das Haar
KR101859500B1 (ko) 2010-12-01 2018-05-21 (주)아모레퍼시픽 3차원 매트릭스
FR2976001B1 (fr) 2011-05-30 2014-10-31 Oreal Modele de cuir chevelu reconstruit et procede de screening de molecules actives
WO2013121427A1 (en) 2012-02-13 2013-08-22 Gamida-Cell Ltd. Mesenchymal stem cells conditioned medium and methods of generating and using the same
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
DE102012220154A1 (de) 2012-11-06 2014-05-08 Henkel Ag & Co. Kgaa Mund- und Zahnpflege- und -reinigungsmittel mit Vitamin E
JP2014204711A (ja) * 2013-03-19 2014-10-30 国立大学法人 千葉大学 三次元培養皮膚モデルの製造方法およびその利用
WO2014179559A1 (en) * 2013-05-03 2014-11-06 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Skin substitutes and methods for hair follicle neogenesis
CN103721294B (zh) * 2013-12-27 2015-05-13 太原理工大学 一种人体表皮组织的快速构建制备方法
DE102014212921A1 (de) 2014-07-03 2016-01-07 Henkel Ag & Co. Kgaa Verwendung von speziellen Oligopeptiden zur Stimulierung des natürlichen Pigmentierungsprozesses in Hautanhangsgebilden
CN104195101B (zh) * 2014-09-09 2016-04-13 武斌 一种毛囊单位保存培养液
CN104491931B (zh) * 2014-12-02 2017-04-12 清华大学深圳研究生院 含有皮脂腺的皮肤组织及其形成方法和用途
SG11201803061UA (en) 2015-10-21 2018-05-30 Univ Indiana Res & Tech Corp Methods of generating human inner ear sensory epithelia and sensory neurons
AU2016342015B2 (en) 2015-10-21 2021-07-01 Indiana University Research And Technology Corporation Derivation of human skin organoids from pluripotent stem cells
DE102015119877B4 (de) 2015-11-17 2017-09-21 Technische Universität Berlin Verfahren zur Herstellung eines Hautäquivalents sowie dessen Verwendung für in vitro Tests und in vivo Transplantate
CN109415691A (zh) * 2016-06-21 2019-03-01 株式会社器官再生工学 用于产生具有毛囊、皮脂腺和毛孔的人工皮肤的方法
CN109735486B (zh) * 2019-01-31 2022-02-22 中国疾病预防控制中心辐射防护与核安全医学所 一种用于研究uvb照射致早衰的原代黑素细胞培养方法
CN112300981A (zh) * 2020-11-14 2021-02-02 厦门思明银河整形外科门诊部有限公司 一种体外培养毛囊的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8604360D0 (en) * 1986-02-21 1986-03-26 Univ Dundee Stimulation of hair growth
FR2612938B1 (fr) * 1987-03-26 1989-06-23 Cird Procede d'obtention d'un equivalent de peau et equivalent de peau correspondant
WO1997025995A1 (en) * 1996-01-18 1997-07-24 Johnson & Johnson Consumer Products, Inc. Methods for regenerating scarless skin and compositions used therein
CA2253724A1 (en) * 1996-04-26 1997-11-06 Case Western Reserve University Skin regeneration using mesenchymal stem cells
AU8282998A (en) * 1997-07-01 1999-01-25 Jerry E. Cooley Method for producing new hair growth
WO2000029553A1 (en) * 1998-11-19 2000-05-25 Organogenesis Inc. Bioengineered tissue constructs and methods for producing and using them
EP1005873B1 (de) * 1998-11-30 2003-04-09 IsoTis N.V. Kunsthaut

Also Published As

Publication number Publication date
DE10162814A1 (de) 2003-07-10
EP1455854B1 (de) 2005-05-25
JP2005525088A (ja) 2005-08-25
EP1455854A1 (de) 2004-09-15
ATE296124T1 (de) 2005-06-15
ES2243801T3 (es) 2005-12-01
DE10162814B4 (de) 2005-06-23
AU2002366280A1 (en) 2003-06-30
WO2003051419A1 (en) 2003-06-26
DE60204352T2 (de) 2006-01-26

Similar Documents

Publication Publication Date Title
DE60204352D1 (de) Haut/haar-äquivalent mit rekonstruierten papillen
DE69204671D1 (de) Kosmetisches oder pharmazeutisches, insbesondere dermatologisches mittel enthaltend einen cyperus extrakt, zur förderung des haut oder haare pigmentierung und herstellungsverfahren.
AR028114A1 (es) DISPOSITIVO PARA LA APLICACION DE UN PRODUCTO, COSMETICO O DE TRATAMIENTO, SOBRE LAS HIERBAS QUERATíNICAS, PARTICULARMENTE LAS PESTANAS O LAS CEJAS
ATE262313T1 (de) Kosmetisches mittel enthaltend maulbeerbaumextrakt und retinoide
AR024807A1 (es) Un dispositivo aplicador para la aplicacion de un producto tal como por ejemplo un producto cosmetico, a las pestanas y cejas.
AU2001240940A1 (en) Cosmetic and dermatological composition for psoriatic skin, scalp treatment and care
BR0106967B1 (pt) dispositivo de acondicionamento e/ou de aplicação de um produto cosmético e/ou de cuidados a ser aplicado à pele, cabelo ou unhas e processo de fabricação do dispositivo.
WO2004021968A3 (en) Solution for ungual application
DE60110342T8 (de) Alpha-Interferon enthaltende Hautpflegemittel
ATE311849T1 (de) Verwendung von kosmetische und pharmazeutische zubereitungen enthaltend 2-decarboxy-2-phosphino prostaglandinderivate
ITMI20001300A0 (it) Composizioni cosmetiche per la cura del cuoio capelluto e dei capelli
ATE489999T1 (de) Kit zum schminken und/oder zur pflege zur bereitstellung eines volumeneffekts
DE50115326D1 (de) Kosmetische und dermatologische haarbehandlungsmittel
ATE259210T1 (de) Trichologische lotion für die topische anwendung
DK1290145T3 (da) Tredimensional hudmodel
ATE345160T1 (de) Topisches produkt mit visuellem indikator
AU2002347271A1 (en) Cosmetic composition for human skin and hair care
AU2003293764A8 (en) Make-up processes and processes for application of a skin care product, and devices used in the implementation of such processes
ATE369185T1 (de) Riechstoffmischungen mit gesteigerter geruchstärke
ITMO20020363A0 (it) Lozione per la cura dei capelli.
ATE326200T1 (de) Einbringen von kosmetika in die haut
ATE438376T1 (de) Haut- und haarpflegezubereitung enthaltend proteinhydrolysate
AU2001284140A1 (en) Cosmetic and/or dermatological composition with enhanced hydrating activity, comprising a crosslinked polysiloxane
DE60326536D1 (de) Aut
RU2001103881A (ru) Мидийный гидролизат для ухода за кожей лица

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: CUTECH S.R.L., PADOVA, IT

Owner name: HENKEL AG & CO. KGAA, 40589 DUESSELDORF, DE