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DE602005025202D1 - Subtilasevarianten mit veränderter immunogenität - Google Patents

Subtilasevarianten mit veränderter immunogenität

Info

Publication number
DE602005025202D1
DE602005025202D1 DE602005025202T DE602005025202T DE602005025202D1 DE 602005025202 D1 DE602005025202 D1 DE 602005025202D1 DE 602005025202 T DE602005025202 T DE 602005025202T DE 602005025202 T DE602005025202 T DE 602005025202T DE 602005025202 D1 DE602005025202 D1 DE 602005025202D1
Authority
DE
Germany
Prior art keywords
immunogenity
changed
subtilase variants
subtilases
subtilase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005025202T
Other languages
English (en)
Inventor
Stefan Minning
Henriette Draborg
Erwing Ludo Roggen
Nanna Kristensen Soni
Ninna Willestofte Berg
Stina Thulesen Lyngstrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novozymes AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes AS filed Critical Novozymes AS
Publication of DE602005025202D1 publication Critical patent/DE602005025202D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE602005025202T 2004-04-02 2005-04-01 Subtilasevarianten mit veränderter immunogenität Expired - Lifetime DE602005025202D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200400535 2004-04-02
PCT/DK2005/000225 WO2005095592A2 (en) 2004-04-02 2005-04-01 Subtilase variants having altered immunogenicity

Publications (1)

Publication Number Publication Date
DE602005025202D1 true DE602005025202D1 (de) 2011-01-20

Family

ID=35064451

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005025202T Expired - Lifetime DE602005025202D1 (de) 2004-04-02 2005-04-01 Subtilasevarianten mit veränderter immunogenität

Country Status (6)

Country Link
US (2) US7824896B2 (de)
EP (1) EP1735433B1 (de)
CN (2) CN1969042B (de)
AT (1) ATE491025T1 (de)
DE (1) DE602005025202D1 (de)
WO (1) WO2005095592A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7824896B2 (en) * 2004-04-02 2010-11-02 Novozymes A/S Subtilase variants having altered lmmunogenicity
ES2763235T3 (es) * 2014-12-15 2020-05-27 Henkel Ag & Co Kgaa Composición detergente que comprende variantes de subtilasa
US11162089B2 (en) * 2015-06-18 2021-11-02 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP3275985A1 (de) * 2016-07-26 2018-01-31 The Procter and Gamble Company Spülmittelzusammensetzung für automatisches geschirrspülen
EP3275989A1 (de) * 2016-07-26 2018-01-31 The Procter and Gamble Company Spülmittelzusammensetzung für automatisches geschirrspülen
US11798657B2 (en) * 2019-09-16 2023-10-24 Burzin Bhavnagri System and method for creating lead compounds, and compositions thereof
JP2025518489A (ja) 2022-05-14 2025-06-17 ノボザイムス アクティーゼルスカブ 植物病原体の寄生及び感染を予防、処置、抑制及び／又は排除するための組成物及び方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK6488D0 (da) * 1988-01-07 1988-01-07 Novo Industri As Enzymer
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
JP3355186B2 (ja) * 1990-12-05 2002-12-09 ノボザイムス アクティーゼルスカブ 改変したエピトープを有するタンパク質及びその製造のための方法
JP3471797B2 (ja) * 1991-05-01 2003-12-02 ノボザイムス アクティーゼルスカブ 安定化酵素及び洗剤
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
US5837517A (en) * 1995-05-05 1998-11-17 Novo Nordisk A/S Protease variants and compositions
KR100591553B1 (ko) * 1996-11-04 2006-06-19 노보자임스 에이/에스 섭틸라제 변종과 조성물
US6773907B2 (en) * 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
US6835550B1 (en) * 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
CN1323345A (zh) * 1998-10-13 2001-11-21 诺沃奇梅兹有限公司 具有降低的免疫应答的修饰多肽
US6461849B1 (en) * 1998-10-13 2002-10-08 Novozymes, A/S Modified polypeptide
US6376450B1 (en) * 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
DE69916306T2 (de) * 1998-10-30 2005-05-04 Novozymes A/S Niedrigallergene proteinvarianten
DK1141205T3 (da) * 1998-12-18 2007-06-18 Novozymes As Subtilase-enzymer fra I-S1 og I-S2 sub-grupperne, som har en yderligere aminosyrerest i en aktiv site loop region
BR0012660A (pt) * 1999-07-22 2002-04-09 Procter & Gamble Variante de protease tipo subtilisina; composição de limpeza; e composição de cuidado pessoal
WO2001044452A1 (en) * 1999-12-15 2001-06-21 Novozymes A/S Subtilase variants having an improved wash performance on egg stains
US6727085B2 (en) * 1999-12-15 2004-04-27 Fanoe Tina Sejersgaard Subtilase variants having an improved wash performance on egg stains
AU4981101A (en) * 2000-04-03 2001-10-15 Maxygen Inc Subtilisin variants
AR030462A1 (es) 2000-08-21 2003-08-20 Novozymes As Novedosas enzimas subtilasas que tienen una reducida tendencia hacia su inhibicion por las sustancias presentes en los huevos
AU2002254374A1 (en) * 2001-03-23 2002-10-08 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
DE10163883A1 (de) * 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14390) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
AU2002353178C1 (en) 2001-12-31 2011-02-03 Genencor International, Inc. Proteases producing an altered immunological response and methods of making and using the same
MXPA04006809A (es) * 2002-01-16 2004-10-11 Genencor Int Variantes de proteasa substituidas con multiplos.
AU2003239783A1 (en) * 2002-06-26 2004-01-19 Novozymes A/S Subtilases and subtilase variants having altered immunogenicity
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
US7824896B2 (en) * 2004-04-02 2010-11-02 Novozymes A/S Subtilase variants having altered lmmunogenicity

Also Published As

Publication number Publication date
ATE491025T1 (de) 2010-12-15
WO2005095592A2 (en) 2005-10-13
US20080280344A1 (en) 2008-11-13
US20110009308A1 (en) 2011-01-13
EP1735433A2 (de) 2006-12-27
US8389262B2 (en) 2013-03-05
CN1969042A (zh) 2007-05-23
CN103820423A (zh) 2014-05-28
US7824896B2 (en) 2010-11-02
WO2005095592A3 (en) 2006-12-14
CN1969042B (zh) 2014-09-24
EP1735433B1 (de) 2010-12-08

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