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DE602005007154D1 - Mikrofluidische Vorrichtung mit einem Mikrokanal mit mehreren Elektromagneten, und Verfahren zur Mischung von Proben und zur Zellyse durch die Verwendung der mikrofluidischen Vorrichtung - Google Patents

Mikrofluidische Vorrichtung mit einem Mikrokanal mit mehreren Elektromagneten, und Verfahren zur Mischung von Proben und zur Zellyse durch die Verwendung der mikrofluidischen Vorrichtung

Info

Publication number
DE602005007154D1
DE602005007154D1 DE602005007154T DE602005007154T DE602005007154D1 DE 602005007154 D1 DE602005007154 D1 DE 602005007154D1 DE 602005007154 T DE602005007154 T DE 602005007154T DE 602005007154 T DE602005007154 T DE 602005007154T DE 602005007154 D1 DE602005007154 D1 DE 602005007154D1
Authority
DE
Germany
Prior art keywords
microfluidic device
microchannel
electromagnets
methods
cell lysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005007154T
Other languages
English (en)
Inventor
Jin-Tae Kim
Kwang-Wook Oh
Yoon-Kyoung Cho
Sang-Hyun Peak
Sook-Young Kim
Chin-Sung Park
Kak Namkoong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Samsung Electronics Co Ltd
Original Assignee
Samsung Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samsung Electronics Co Ltd filed Critical Samsung Electronics Co Ltd
Publication of DE602005007154D1 publication Critical patent/DE602005007154D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C12N1/066—Lysis of microorganisms by physical methods
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/451—Magnetic mixers; Mixers with magnetically driven stirrers wherein the mixture is directly exposed to an electromagnetic field without use of a stirrer, e.g. for material comprising ferromagnetic particles or for molten metal

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
DE602005007154T 2004-11-23 2005-11-22 Mikrofluidische Vorrichtung mit einem Mikrokanal mit mehreren Elektromagneten, und Verfahren zur Mischung von Proben und zur Zellyse durch die Verwendung der mikrofluidischen Vorrichtung Active DE602005007154D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020040096152A KR100634525B1 (ko) 2004-11-23 2004-11-23 복수 개의 전자석이 배치되어 있는 마이크로채널을포함하는 미세유동 장치, 그를 이용하여 시료를 혼합하는방법 및 세포를 용해하는 방법

Publications (1)

Publication Number Publication Date
DE602005007154D1 true DE602005007154D1 (de) 2008-07-10

Family

ID=35840483

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005007154T Active DE602005007154D1 (de) 2004-11-23 2005-11-22 Mikrofluidische Vorrichtung mit einem Mikrokanal mit mehreren Elektromagneten, und Verfahren zur Mischung von Proben und zur Zellyse durch die Verwendung der mikrofluidischen Vorrichtung

Country Status (7)

Country Link
US (1) US20060140051A1 (de)
EP (1) EP1658890B1 (de)
JP (1) JP2006142294A (de)
KR (1) KR100634525B1 (de)
CN (1) CN1779430A (de)
DE (1) DE602005007154D1 (de)
TW (1) TWI276462B (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2290731A1 (en) * 1999-11-26 2001-05-26 D. Jed Harrison Apparatus and method for trapping bead based reagents within microfluidic analysis system
US6432290B1 (en) 1999-11-26 2002-08-13 The Governors Of The University Of Alberta Apparatus and method for trapping bead based reagents within microfluidic analysis systems
EP2404676A1 (de) 2002-12-30 2012-01-11 The Regents of the University of California Mikrofluidische Steuerungsstrukturen
US7799553B2 (en) 2004-06-01 2010-09-21 The Regents Of The University Of California Microfabricated integrated DNA analysis system
CN102759466A (zh) 2004-09-15 2012-10-31 英特基因有限公司 微流体装置
US7745207B2 (en) 2006-02-03 2010-06-29 IntegenX, Inc. Microfluidic devices
US7766033B2 (en) 2006-03-22 2010-08-03 The Regents Of The University Of California Multiplexed latching valves for microfluidic devices and processors
US20090186420A1 (en) * 2006-06-02 2009-07-23 Koninklijke Philips Electronics N.V. Microelectronic sensor device with washing means
KR100809866B1 (ko) * 2006-06-16 2008-03-06 연세대학교 산학협력단 미세유체채널 및 자장을 이용한 아폽토틱 세포의 검침·분리방법 및 이를 위한 장치
US8999732B2 (en) * 2006-06-21 2015-04-07 Spinomix, S.A. Method for manipulating magnetic particles in a liquid medium
AU2007274748A1 (en) * 2006-06-21 2008-01-24 Spinomix S.A. A device and method for manipulating and mixing magnetic particles in a liquid medium
US8870446B2 (en) 2006-06-21 2014-10-28 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
US8585279B2 (en) * 2006-06-21 2013-11-19 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
KR100754409B1 (ko) 2006-08-30 2007-08-31 삼성전자주식회사 원심력을 이용한 자성비드 팩킹 유닛, 이를 구비한미세유동 장치 및 상기 미세유동 장치를 이용한 면역학적검정 방법
US8841116B2 (en) 2006-10-25 2014-09-23 The Regents Of The University Of California Inline-injection microdevice and microfabricated integrated DNA analysis system using same
KR100736693B1 (ko) * 2006-11-09 2007-07-06 백성훈 믹서
GB2446204A (en) * 2007-01-12 2008-08-06 Univ Brunel A Microfluidic device
US20090050569A1 (en) * 2007-01-29 2009-02-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
US10001496B2 (en) 2007-01-29 2018-06-19 Gearbox, Llc Systems for allergen detection
KR20100028526A (ko) 2007-02-05 2010-03-12 마이크로칩 바이오테크놀로지스, 인크. 마이크로유체 및 나노유체 장치, 시스템 및 응용
DE602007013010D1 (de) * 2007-05-15 2011-04-21 Corning Inc Mikrofluidische und selbstverzögernde oszillierende Mischer sowie Vorrichtungen und Verfahren zu deren Verwendung
US8454906B2 (en) 2007-07-24 2013-06-04 The Regents Of The University Of California Microfabricated droplet generator for single molecule/cell genetic analysis in engineered monodispersed emulsions
CN101990516B (zh) * 2008-01-22 2015-09-09 英特基因有限公司 多用试样准备系统及其在集成分析系统中的使用
CN101564659B (zh) * 2008-04-25 2012-07-18 鸿富锦精密工业（深圳）有限公司 微流体混合装置
KR20110111449A (ko) * 2008-12-31 2011-10-11 인터젠엑스 인크. 미세유체 칩을 갖는 기구
US8388908B2 (en) 2009-06-02 2013-03-05 Integenx Inc. Fluidic devices with diaphragm valves
BRPI1010169A2 (pt) 2009-06-05 2016-03-29 Integenx Inc sistema que se ajusta dentro de um invólucro de não mais que 10 pés3, cartucho, artigo em forma legível por computador, método, sistema configurado para realizar um método, sistema óptico, instrumento e dispositivo.
US8584703B2 (en) 2009-12-01 2013-11-19 Integenx Inc. Device with diaphragm valve
KR101377173B1 (ko) * 2010-02-26 2014-03-26 성균관대학교산학협력단 미세 유체 장치
KR101377172B1 (ko) * 2010-02-26 2014-03-26 성균관대학교산학협력단 미세 유체 장치
US8512538B2 (en) 2010-05-28 2013-08-20 Integenx Inc. Capillary electrophoresis device
US9121058B2 (en) 2010-08-20 2015-09-01 Integenx Inc. Linear valve arrays
EP2606242A4 (de) 2010-08-20 2016-07-20 Integenx Inc Mikrofluidikvorrichtungen mit mechanisch abgedichteten membranventilen
US20120132593A1 (en) * 2010-11-30 2012-05-31 General Electric Company Systems and methods for magnetic separation of biological materials
US10865440B2 (en) 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
US20150136604A1 (en) 2011-10-21 2015-05-21 Integenx Inc. Sample preparation, processing and analysis systems
DE102012210077A1 (de) * 2012-06-15 2013-12-19 Siemens Aktiengesellschaft Verfahren und Anordnung zur Markierung von Zellen in einer Zellsuspension
DE102013006235B4 (de) * 2013-04-11 2017-07-27 Forschungszentrum Jülich GmbH Vorrichtung zum Mischen von Flüssigkeiten in einem Mikrokanal
CN105873681B (zh) 2013-11-18 2019-10-11 尹特根埃克斯有限公司 用于样本分析的卡盒和仪器
GB2544198B (en) 2014-05-21 2021-01-13 Integenx Inc Fluidic cartridge with valve mechanism
US10690627B2 (en) 2014-10-22 2020-06-23 IntegenX, Inc. Systems and methods for sample preparation, processing and analysis
CN106179544B (zh) * 2016-07-14 2018-07-06 大连海事大学 基于微流控芯片的便携式免疫磁珠三维混合装置及使用方法
GB201617388D0 (en) 2016-10-13 2016-11-30 Randox Laboratories Limited Method of extracting material from a fluid and extractor
CN107029612A (zh) * 2016-11-08 2017-08-11 华中科技大学 一种基于共平面线圈组的微流控快速混合器
CN112444438B (zh) * 2019-08-27 2023-12-05 深圳市帝迈生物技术有限公司 样本检测设备及其混匀装置
CN110823875A (zh) * 2019-11-05 2020-02-21 苏州长光华医生物医学工程有限公司 一种化学发光分析仪及其反应装置、磁力摇匀装置
KR102442341B1 (ko) 2020-04-14 2022-09-14 한국과학기술연구원 확산 챔버 및 채널을 포함하는 생체 미세환경 모사 미세유체 장치
CA3191731A1 (en) * 2020-08-14 2022-02-17 Alveo Technologies, Inc. Systems and methods of sample depositing and testing
US20230381779A1 (en) * 2020-10-20 2023-11-30 Hewlett-Packard Development Company, L.P. Cell lysis with magnetic particles and a resistor
USD1069156S1 (en) 2023-04-10 2025-04-01 Becton, Dickinson And Company Dispensing device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541072A (en) * 1994-04-18 1996-07-30 Immunivest Corporation Method for magnetic separation featuring magnetic particles in a multi-phase system
DE4243692C1 (de) * 1992-12-18 1993-11-25 Magnettech Ges Fuer Mes Und St Verfahren und Anordnung zum Aufschließen von biologischen Zellen
US5655665A (en) * 1994-12-09 1997-08-12 Georgia Tech Research Corporation Fully integrated micromachined magnetic particle manipulator and separator
FR2781500B1 (fr) * 1998-07-23 2000-09-08 Bio Merieux Dispositif perfectionne et procede de lyse de micro-organismes
US6408884B1 (en) * 1999-12-15 2002-06-25 University Of Washington Magnetically actuated fluid handling devices for microfluidic applications
WO2001089985A2 (en) * 2000-05-23 2001-11-29 Arizona Board Of Regents Novel method of creating micro-structures for micro-fluidic applications
US6467946B1 (en) * 2001-04-24 2002-10-22 Dade Microscan Inc. Method and apparatus for mixing liquid samples in a container using rotating magnetic fields
EP1331035A1 (de) * 2002-01-23 2003-07-30 F. Hoffmann-La Roche AG Apparat zum Zurückhalten von Magnetteilchen in einer von einer Flüssigkeit durchströmte Zelle
US20040018611A1 (en) * 2002-07-23 2004-01-29 Ward Michael Dennis Microfluidic devices for high gradient magnetic separation
FR2845298B1 (fr) * 2002-10-08 2004-11-12 Commissariat Energie Atomique Dispositif pour le melange de fluides

Also Published As

Publication number Publication date
US20060140051A1 (en) 2006-06-29
EP1658890A2 (de) 2006-05-24
KR20060057093A (ko) 2006-05-26
TW200626223A (en) 2006-08-01
CN1779430A (zh) 2006-05-31
EP1658890B1 (de) 2008-05-28
KR100634525B1 (ko) 2006-10-16
EP1658890A3 (de) 2006-09-06
JP2006142294A (ja) 2006-06-08
TWI276462B (en) 2007-03-21

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