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DE602005006534D1 - Piperidinyl-prostaglandin-e-analoga - Google Patents

Piperidinyl-prostaglandin-e-analoga

Info

Publication number
DE602005006534D1
DE602005006534D1 DE602005006534T DE602005006534T DE602005006534D1 DE 602005006534 D1 DE602005006534 D1 DE 602005006534D1 DE 602005006534 T DE602005006534 T DE 602005006534T DE 602005006534 T DE602005006534 T DE 602005006534T DE 602005006534 D1 DE602005006534 D1 DE 602005006534D1
Authority
DE
Germany
Prior art keywords
prostaglandin
piperidinyl
analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005006534T
Other languages
English (en)
Inventor
David W Old
Danny T Dinh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of DE602005006534D1 publication Critical patent/DE602005006534D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/45Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE602005006534T 2004-01-22 2005-01-14 Piperidinyl-prostaglandin-e-analoga Expired - Lifetime DE602005006534D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/763,702 US6977260B2 (en) 2004-01-22 2004-01-22 Piperidinyl prostaglandin E analogs
PCT/US2005/001461 WO2005072735A1 (en) 2004-01-22 2005-01-14 Piperidinyl prostaglandin e analogs

Publications (1)

Publication Number Publication Date
DE602005006534D1 true DE602005006534D1 (de) 2008-06-19

Family

ID=34795110

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005006534T Expired - Lifetime DE602005006534D1 (de) 2004-01-22 2005-01-14 Piperidinyl-prostaglandin-e-analoga

Country Status (11)

Country Link
US (1) US6977260B2 (de)
EP (1) EP1722795B1 (de)
JP (1) JP4740883B2 (de)
AR (1) AR047436A1 (de)
AT (1) ATE394101T1 (de)
AU (1) AU2005209209B2 (de)
CA (1) CA2553387C (de)
DE (1) DE602005006534D1 (de)
ES (1) ES2303672T3 (de)
TW (1) TWI348370B (de)
WO (1) WO2005072735A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7326716B2 (en) * 2003-06-06 2008-02-05 Allergan, Inc. Treatment of inflammatory bowel disease
JP2008517941A (ja) * 2004-10-21 2008-05-29 デューク・ユニバーシティー 眼科用薬剤
US20070254920A1 (en) * 2006-04-26 2007-11-01 Aerie Pharmaceuticals, Inc. Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3220156C2 (de) * 1982-05-28 1990-01-25 Heida Houston Tex. Thurlow Mit Metallgriffen, insbesondere Edelstahlgriffen, versehenes Koch- und Bratgeschirr mit Deckel
IT1225716B (it) * 1988-10-26 1990-11-22 Esacontrol Spa Dispositivo per la protezione dei rele' di binario dai disturbi elettrici
US4994274A (en) * 1989-07-27 1991-02-19 Allergan, Inc. Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using
US5028624A (en) * 1989-07-27 1991-07-02 Allergan, Inc. Intraocular pressure reducing 9,15-diacyl prostaglandins
CA2021316C (en) 1989-07-27 2000-10-24 Ming Fai Chan Intraocular pressure reducing 11-acyl prostaglandins
US5034413A (en) 1989-07-27 1991-07-23 Allergan, Inc. Intraocular pressure reducing 9,11-diacyl prostaglandins
DE4318713C1 (de) * 1993-06-07 1994-09-15 Daimler Benz Ag Zahnräderwechselgetriebe der Vorgelegebauart
DE60334905D1 (de) * 2002-06-06 2010-12-23 Merck Frosst Canada Ltd 1,5-disubstituierte pyrrolid-2-on-derivate zur verwendung als ep4 rezeptor agonisten zur behandlung von augenkrankheiten wie z.b. glaukom
US7053085B2 (en) 2003-03-26 2006-05-30 Merck & Co. Inc. EP4 receptor agonist, compositions and methods thereof
BRPI0406717A (pt) * 2003-01-10 2005-12-20 Hoffmann La Roche Composto, composição farmacêutica que compreende o mesmo, método de tratamento de uma enfermidade em um mamìfero, utilização do composto e processo para a sua produção
JP2006527189A (ja) * 2003-06-06 2006-11-30 アラーガン、インコーポレイテッド ピペリジニルプロスタグランジンe類似体
US6747037B1 (en) * 2003-06-06 2004-06-08 Allergan, Inc. Piperidinyl prostaglandin E analogs

Also Published As

Publication number Publication date
EP1722795B1 (de) 2008-05-07
EP1722795A1 (de) 2006-11-22
JP4740883B2 (ja) 2011-08-03
TW200533350A (en) 2005-10-16
AU2005209209B2 (en) 2012-03-08
AU2005209209A1 (en) 2005-08-11
CA2553387C (en) 2013-04-02
TWI348370B (en) 2011-09-11
JP2007520489A (ja) 2007-07-26
HK1099203A1 (en) 2007-08-10
US6977260B2 (en) 2005-12-20
CA2553387A1 (en) 2005-08-11
ATE394101T1 (de) 2008-05-15
ES2303672T3 (es) 2008-08-16
US20050164990A1 (en) 2005-07-28
WO2005072735A1 (en) 2005-08-11
AR047436A1 (es) 2006-01-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition