DE602004028007D1 - Interleukin-9 antagonist-muteine und ihre pharmakologischen anwendungsverfahren - Google Patents
Interleukin-9 antagonist-muteine und ihre pharmakologischen anwendungsverfahrenInfo
- Publication number
- DE602004028007D1 DE602004028007D1 DE602004028007T DE602004028007T DE602004028007D1 DE 602004028007 D1 DE602004028007 D1 DE 602004028007D1 DE 602004028007 T DE602004028007 T DE 602004028007T DE 602004028007 T DE602004028007 T DE 602004028007T DE 602004028007 D1 DE602004028007 D1 DE 602004028007D1
- Authority
- DE
- Germany
- Prior art keywords
- mutines
- interleukin
- antagonist
- muteins
- application procedures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 4
- 229940123357 Interleukin 9 antagonist Drugs 0.000 title 1
- 230000000144 pharmacologic effect Effects 0.000 title 1
- 102000000585 Interleukin-9 Human genes 0.000 abstract 6
- 108010002335 Interleukin-9 Proteins 0.000 abstract 6
- 239000000203 mixture Substances 0.000 abstract 2
- 206010006458 Bronchitis chronic Diseases 0.000 abstract 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 206010014561 Emphysema Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010025323 Lymphomas Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 208000007451 chronic bronchitis Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 206010020718 hyperplasia Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 210000003097 mucus Anatomy 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5425—IL-9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47063003P | 2003-05-14 | 2003-05-14 | |
| PCT/US2004/015168 WO2004103295A2 (en) | 2003-05-14 | 2004-05-14 | Interleukin-9 antagonist muteins and their pharmacological methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004028007D1 true DE602004028007D1 (de) | 2010-08-19 |
Family
ID=33476726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004028007T Expired - Lifetime DE602004028007D1 (de) | 2003-05-14 | 2004-05-14 | Interleukin-9 antagonist-muteine und ihre pharmakologischen anwendungsverfahren |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7423123B2 (de) |
| EP (1) | EP1622568B1 (de) |
| AT (1) | ATE473239T1 (de) |
| DE (1) | DE602004028007D1 (de) |
| WO (1) | WO2004103295A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7635754B2 (en) | 2004-09-22 | 2009-12-22 | Aerovance, Inc. | Interleukin-9 and interleukin-4 chimeric antagonist muteins and methods of using same |
| WO2015089217A2 (en) | 2013-12-10 | 2015-06-18 | Bionz, Llc | Methods of developing selective peptide antagonists |
| ES2989085T3 (es) | 2011-01-18 | 2024-11-25 | Bioniz Therapeutics Inc | Composiciones para modular la actividad de citoquinas gamma-c |
| WO2012129394A2 (en) * | 2011-03-22 | 2012-09-27 | Brigham And Women's Hospital, Inc. | Methods and compositions for the treatment of cancer |
| WO2012178137A1 (en) | 2011-06-24 | 2012-12-27 | Gillies Stephen D | Light chain immunoglobulin fusion proteins and methods of use thereof |
| ES2884357T3 (es) | 2015-10-09 | 2021-12-10 | Bioniz Llc | Modulación de la actividad de las citocinas gamma-c |
| US12030936B2 (en) | 2019-05-03 | 2024-07-09 | Bioniz Therapeutics, Inc. | Modulating the effects of gamma-c-cytokine signaling for the treatment of alopecia and alopecia associated disorders |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5587302A (en) * | 1988-09-19 | 1996-12-24 | Ludwig Institute For Cancer Research | T cell growth factor |
| US5208218A (en) * | 1988-09-19 | 1993-05-04 | Ludwig Institute For Cancer Research | T cell growth factor glycoproteins |
| US5472841A (en) | 1990-06-11 | 1995-12-05 | Nexstar Pharmaceuticals, Inc. | Methods for identifying nucleic acid ligands of human neutrophil elastase |
| ZA967182B (en) | 1995-08-24 | 1998-05-25 | Magainin Pharma | Asthma associated factors as targets for treating atopic allergies including asthma and related disorders. |
| GB9810999D0 (en) * | 1998-05-21 | 1998-07-22 | Goken Joop | Materials and methods relating to the expression of genes |
| US20040219149A1 (en) * | 2001-06-08 | 2004-11-04 | Yuhong Zhou | Methods for the modulation of il-13 |
-
2004
- 2004-05-14 EP EP04752242A patent/EP1622568B1/de not_active Expired - Lifetime
- 2004-05-14 DE DE602004028007T patent/DE602004028007D1/de not_active Expired - Lifetime
- 2004-05-14 AT AT04752242T patent/ATE473239T1/de not_active IP Right Cessation
- 2004-05-14 WO PCT/US2004/015168 patent/WO2004103295A2/en active Application Filing
- 2004-05-14 US US10/845,632 patent/US7423123B2/en not_active Expired - Fee Related
-
2008
- 2008-08-22 US US12/197,139 patent/US20090148403A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1622568A4 (de) | 2008-12-03 |
| US20090148403A1 (en) | 2009-06-11 |
| WO2004103295A2 (en) | 2004-12-02 |
| EP1622568A2 (de) | 2006-02-08 |
| US20040247566A1 (en) | 2004-12-09 |
| EP1622568B1 (de) | 2010-07-07 |
| WO2004103295A3 (en) | 2007-03-15 |
| US7423123B2 (en) | 2008-09-09 |
| ATE473239T1 (de) | 2010-07-15 |
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