DE602004017326D1 - Tetrahydrocarbazolderivate und deren pharmazeutische verwendung - Google Patents
Tetrahydrocarbazolderivate und deren pharmazeutische verwendungInfo
- Publication number
- DE602004017326D1 DE602004017326D1 DE602004017326T DE602004017326T DE602004017326D1 DE 602004017326 D1 DE602004017326 D1 DE 602004017326D1 DE 602004017326 T DE602004017326 T DE 602004017326T DE 602004017326 T DE602004017326 T DE 602004017326T DE 602004017326 D1 DE602004017326 D1 DE 602004017326D1
- Authority
- DE
- Germany
- Prior art keywords
- tetrahydrocarbazol
- derivatives
- pharmaceutical use
- compounds
- useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47725103P | 2003-06-10 | 2003-06-10 | |
| US49782303P | 2003-08-26 | 2003-08-26 | |
| PCT/US2004/017660 WO2004110999A1 (en) | 2003-06-10 | 2004-06-07 | Tetrahydrocarbazole derivatives and their pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004017326D1 true DE602004017326D1 (de) | 2008-12-04 |
Family
ID=33555453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004017326T Expired - Lifetime DE602004017326D1 (de) | 2003-06-10 | 2004-06-07 | Tetrahydrocarbazolderivate und deren pharmazeutische verwendung |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7351733B2 (de) |
| EP (1) | EP1654228B1 (de) |
| JP (1) | JP2007501284A (de) |
| KR (1) | KR20060017545A (de) |
| AT (1) | ATE411981T1 (de) |
| AU (1) | AU2004247676A1 (de) |
| BR (1) | BRPI0411085A (de) |
| CA (1) | CA2528321A1 (de) |
| CO (1) | CO5660287A2 (de) |
| DE (1) | DE602004017326D1 (de) |
| ES (1) | ES2314446T3 (de) |
| IL (1) | IL171974A0 (de) |
| MA (1) | MA27880A1 (de) |
| NO (1) | NO20055741L (de) |
| RU (1) | RU2318810C2 (de) |
| WO (1) | WO2004110999A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7622494B2 (en) | 2003-08-26 | 2009-11-24 | Smithkline Beecham Corporation | Chemical compounds |
| EP1737461B1 (de) | 2004-03-15 | 2012-12-12 | PTC Therapeutics, Inc. | Carbolin-derivate zur hemmung der angiogenese |
| US8076353B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Inhibition of VEGF translation |
| US8076352B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Administration of carboline derivatives useful in the treatment of cancer and other diseases |
| US7767689B2 (en) | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
| WO2006012310A2 (en) * | 2004-06-25 | 2006-02-02 | Genzyme Corporation | Carbazole derivatives for treating polycystic kidney disease |
| US20090156621A1 (en) * | 2004-11-22 | 2009-06-18 | Kristian Gudmundsson | Hcv inhibitors |
| JP2008520742A (ja) | 2004-11-23 | 2008-06-19 | ピーティーシー セラピューティクス， インコーポレイテッド | Ｖｅｇｆ産生の阻害に有用なカルバゾール誘導体、カルボリン誘導体およびインドール誘導体 |
| WO2007002051A1 (en) * | 2005-06-22 | 2007-01-04 | Smithkline Beecham Corporation | Carboline derivatives and their use as inhibitors of flaviviridae infections |
| WO2013139929A1 (en) * | 2012-03-22 | 2013-09-26 | Ludwig-Maximilians-Universität München | Novel means and methods for treating diseases of the central nervous system, metabolic and cardiac diseases and aging |
| EP2887804B1 (de) | 2012-05-22 | 2021-01-27 | Trustees of Dartmouth College | Cycloalkanyl[b]indolen zur verwendung als glp-1 modulatoren |
| EP2690091A1 (de) | 2012-07-25 | 2014-01-29 | Studiengesellschaft Kohle mbH | Verfahren zur Herstellung von substituierten Indolderivaten |
| KR101671484B1 (ko) | 2016-07-21 | 2016-11-01 | 김정환 | 오셀타미비르(Oseltamivir)를 포함하는 인유두종 바이러스 치료용 약학적 조성물 |
| US10882821B1 (en) | 2017-09-26 | 2021-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes |
| WO2021183980A1 (en) * | 2020-03-13 | 2021-09-16 | Fmc Corporation | Substituted pyrimidines and triazines as herbicides |
| CN113995758B (zh) * | 2021-11-04 | 2023-06-02 | 中山大学 | 咔唑-嘧啶衍生物在制备治疗抗肿瘤药物中的应用 |
| KR102907984B1 (ko) | 2022-11-22 | 2026-01-06 | 이경엽 | 알칼로이드 함유 인유두종 바이러스 감염의 예방 또는 치료용 조성물 |
| KR102907985B1 (ko) | 2022-11-22 | 2026-01-06 | 이경엽 | 인유두종 바이러스 감염에 의한 후두유두종의 예방 또는 치료용 조성물 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE507797C (de) * | 1927-05-14 | 1930-09-20 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung von 1-Aminocarbazol und seinen Derivaten |
| GB8924392D0 (en) * | 1989-10-30 | 1989-12-20 | Bayer Ag | Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides |
| GB9008108D0 (en) * | 1990-04-10 | 1990-06-06 | Bayer Ag | Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles |
| US5100891A (en) | 1991-01-18 | 1992-03-31 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds |
| CA2106642C (en) * | 1992-10-14 | 2005-08-16 | Peter Bod | Carbazolone derivatives and process for preparing the same |
| JP2950433B2 (ja) * | 1995-07-10 | 1999-09-20 | インターナシヨナル・ビジネス・マシーンズ・コーポレーシヨン | バッテリ収納装置 |
| GB0015904D0 (en) | 2000-06-28 | 2000-08-23 | Hoffmann La Roche | Inhibitors of HPV E1 helicase enzyme |
| DE10164564B4 (de) * | 2001-12-14 | 2007-05-16 | Zentaris Gmbh | Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR) |
| IL161626A0 (en) * | 2001-12-14 | 2004-09-27 | Zentaris Gmbh | Tetrahydrocarbozole derivatives as ligands for g-protein coupled receptors (gpcr) |
-
2004
- 2004-06-07 KR KR1020057023781A patent/KR20060017545A/ko not_active Withdrawn
- 2004-06-07 RU RU2005138124/04A patent/RU2318810C2/ru not_active IP Right Cessation
- 2004-06-07 JP JP2006533561A patent/JP2007501284A/ja active Pending
- 2004-06-07 WO PCT/US2004/017660 patent/WO2004110999A1/en not_active Ceased
- 2004-06-07 BR BRPI0411085-4A patent/BRPI0411085A/pt not_active IP Right Cessation
- 2004-06-07 AU AU2004247676A patent/AU2004247676A1/en not_active Abandoned
- 2004-06-07 CA CA002528321A patent/CA2528321A1/en not_active Abandoned
- 2004-06-07 ES ES04776279T patent/ES2314446T3/es not_active Expired - Lifetime
- 2004-06-07 AT AT04776279T patent/ATE411981T1/de not_active IP Right Cessation
- 2004-06-07 DE DE602004017326T patent/DE602004017326D1/de not_active Expired - Lifetime
- 2004-06-07 US US10/560,013 patent/US7351733B2/en not_active Expired - Fee Related
- 2004-06-07 EP EP04776279A patent/EP1654228B1/de not_active Expired - Lifetime
-
2005
- 2005-11-15 IL IL171974A patent/IL171974A0/en unknown
- 2005-12-05 NO NO20055741A patent/NO20055741L/no not_active Application Discontinuation
- 2005-12-09 MA MA28646A patent/MA27880A1/fr unknown
- 2005-12-15 CO CO05126713A patent/CO5660287A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE411981T1 (de) | 2008-11-15 |
| EP1654228B1 (de) | 2008-10-22 |
| US7351733B2 (en) | 2008-04-01 |
| WO2004110999A1 (en) | 2004-12-23 |
| CA2528321A1 (en) | 2004-12-23 |
| US20060161002A1 (en) | 2006-07-20 |
| ES2314446T3 (es) | 2009-03-16 |
| EP1654228A1 (de) | 2006-05-10 |
| JP2007501284A (ja) | 2007-01-25 |
| CO5660287A2 (es) | 2006-07-31 |
| KR20060017545A (ko) | 2006-02-23 |
| BRPI0411085A (pt) | 2006-07-25 |
| IL171974A0 (en) | 2006-04-10 |
| RU2005138124A (ru) | 2006-07-10 |
| NO20055741D0 (no) | 2005-12-05 |
| AU2004247676A1 (en) | 2004-12-23 |
| NO20055741L (no) | 2006-01-06 |
| RU2318810C2 (ru) | 2008-03-10 |
| MA27880A1 (fr) | 2006-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |