DE60141274D1 - Kombinationstherapie zur behandlung respiratorischer krankheiten mittels antikörper und anti-entzündungs wirkstoffe - Google Patents
Kombinationstherapie zur behandlung respiratorischer krankheiten mittels antikörper und anti-entzündungs wirkstoffeInfo
- Publication number
- DE60141274D1 DE60141274D1 DE60141274T DE60141274T DE60141274D1 DE 60141274 D1 DE60141274 D1 DE 60141274D1 DE 60141274 T DE60141274 T DE 60141274T DE 60141274 T DE60141274 T DE 60141274T DE 60141274 D1 DE60141274 D1 DE 60141274D1
- Authority
- DE
- Germany
- Prior art keywords
- antibody
- respiratory diseases
- compositions
- treatment
- active substances
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- 238000002648 combination therapy Methods 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 4
- 241000725643 Respiratory syncytial virus Species 0.000 abstract 2
- 208000023504 respiratory system disease Diseases 0.000 abstract 2
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 229960001334 corticosteroids Drugs 0.000 abstract 1
- 229940100601 interleukin-6 Drugs 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20140400P | 2000-05-03 | 2000-05-03 | |
| PCT/US2001/014193 WO2001082966A1 (en) | 2000-05-03 | 2001-05-03 | Combination therapy of respiratory diseases using antibodies and anti-inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60141274D1 true DE60141274D1 (de) | 2010-03-25 |
Family
ID=22745679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60141274T Expired - Lifetime DE60141274D1 (de) | 2000-05-03 | 2001-05-03 | Kombinationstherapie zur behandlung respiratorischer krankheiten mittels antikörper und anti-entzündungs wirkstoffe |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7208162B2 (de) |
| EP (1) | EP1278546B1 (de) |
| JP (1) | JP2003531867A (de) |
| AT (1) | ATE457177T1 (de) |
| AU (2) | AU2001261137B2 (de) |
| CA (1) | CA2407292A1 (de) |
| DE (1) | DE60141274D1 (de) |
| ES (1) | ES2338098T3 (de) |
| WO (1) | WO2001082966A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2349348T3 (es) * | 2000-01-27 | 2010-12-30 | Medimmune, Llc | Anticuerpos neutralizantes de rsv de ultra alta afinidad. |
| CA2401652A1 (en) * | 2000-03-01 | 2001-09-07 | Medimmune, Inc. | High potency recombinant antibodies and method for producing them |
| US7208162B2 (en) | 2000-05-03 | 2007-04-24 | Medimmune, Inc. | Combination therapy of respiratory diseases using antibodies and anti-inflammatory agents |
| US7179900B2 (en) * | 2000-11-28 | 2007-02-20 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| US6855493B2 (en) * | 2000-11-28 | 2005-02-15 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| GB2388194A (en) * | 2002-05-02 | 2003-11-05 | Nec Technologies | Remote medical monitor utilising a mobile telephone |
| US7132100B2 (en) * | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US7425618B2 (en) * | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| CA2494485A1 (en) * | 2002-07-25 | 2004-02-05 | Medimmune, Inc. | Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies |
| KR20110094361A (ko) | 2003-04-11 | 2011-08-23 | 메디뮨 엘엘씨 | 재조합 ｉｌ９ 항체 및 그의 용도 |
| US20060035859A1 (en) * | 2003-05-16 | 2006-02-16 | Hemispherx Biopharma | Treating severe and acute viral infections |
| WO2006041970A2 (en) * | 2004-10-08 | 2006-04-20 | Abbott Biotechnology Ltd. | Treatment of respiratory syncytial virus (rsv) infection |
| AU2005302453A1 (en) * | 2004-10-29 | 2006-05-11 | Medimmune, Llc | Methods of preventing and treating RSV infections and related conditions |
| JP2009545319A (ja) * | 2006-08-03 | 2009-12-24 | バクシネックス，インコーポレーテッド | 抗ｉｌ−６モノクローナル抗体およびその使用 |
| EP1997830A1 (de) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV-spezifische Bindemoleküle und Mittel zu ihrer Herstellung |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| US11312761B2 (en) | 2016-10-21 | 2022-04-26 | Adimab, Llc | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
| EP3529272A2 (de) | 2016-10-21 | 2019-08-28 | Adimab, LLC | Antikörper gegen das respiratorische synzytial-virus und verfahren zu deren erzeugung und verwendung |
| WO2018075974A2 (en) | 2016-10-21 | 2018-04-26 | Adimab, Llc | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69232706T2 (de) * | 1991-05-01 | 2002-11-28 | Henry M. Jackson Foundation For The Advancement Of Military Medicine, Rockville | Verfahren zur behandlung infektiöser respiratorischer erkrankungen |
| US5824307A (en) * | 1991-12-23 | 1998-10-20 | Medimmune, Inc. | Human-murine chimeric antibodies against respiratory syncytial virus |
| JP2002521334A (ja) * | 1998-07-20 | 2002-07-16 | ブリストルーマイヤーズ スクイブ カンパニー | 置換ベンズイミダゾール抗ウィルス剤 |
| US7208162B2 (en) | 2000-05-03 | 2007-04-24 | Medimmune, Inc. | Combination therapy of respiratory diseases using antibodies and anti-inflammatory agents |
-
2001
- 2001-05-03 US US09/848,377 patent/US7208162B2/en not_active Expired - Lifetime
- 2001-05-03 JP JP2001579839A patent/JP2003531867A/ja active Pending
- 2001-05-03 WO PCT/US2001/014193 patent/WO2001082966A1/en active Application Filing
- 2001-05-03 AT AT01935002T patent/ATE457177T1/de not_active IP Right Cessation
- 2001-05-03 ES ES01935002T patent/ES2338098T3/es not_active Expired - Lifetime
- 2001-05-03 AU AU2001261137A patent/AU2001261137B2/en not_active Expired
- 2001-05-03 CA CA002407292A patent/CA2407292A1/en not_active Abandoned
- 2001-05-03 DE DE60141274T patent/DE60141274D1/de not_active Expired - Lifetime
- 2001-05-03 AU AU6113701A patent/AU6113701A/xx active Pending
- 2001-05-03 EP EP01935002A patent/EP1278546B1/de not_active Expired - Lifetime
-
2007
- 2007-03-06 US US11/714,670 patent/US20070224204A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001261137C1 (en) | 2001-11-12 |
| US7208162B2 (en) | 2007-04-24 |
| JP2003531867A (ja) | 2003-10-28 |
| WO2001082966A1 (en) | 2001-11-08 |
| ATE457177T1 (de) | 2010-02-15 |
| US20070224204A1 (en) | 2007-09-27 |
| ES2338098T3 (es) | 2010-05-04 |
| US20020051787A1 (en) | 2002-05-02 |
| AU2001261137B2 (en) | 2006-05-25 |
| EP1278546B1 (de) | 2010-02-10 |
| AU6113701A (en) | 2001-11-12 |
| CA2407292A1 (en) | 2001-11-08 |
| EP1278546A1 (de) | 2003-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |