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DE60127845D1 - Benzylidenthiazolidindione und ihre verwendung als antimykotische mittel - Google Patents

Benzylidenthiazolidindione und ihre verwendung als antimykotische mittel

Info

Publication number
DE60127845D1
DE60127845D1 DE60127845T DE60127845T DE60127845D1 DE 60127845 D1 DE60127845 D1 DE 60127845D1 DE 60127845 T DE60127845 T DE 60127845T DE 60127845 T DE60127845 T DE 60127845T DE 60127845 D1 DE60127845 D1 DE 60127845D1
Authority
DE
Germany
Prior art keywords
sub
benzylidenthiazolideindione
hydrogen
antimycotic agent
specific substituents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60127845T
Other languages
English (en)
Other versions
DE60127845T2 (de
Inventor
Michael Glen Orchard
Judi Charlotte Neuss
Carl Maurice Swedler Galley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB SA
Original Assignee
UCB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB SA filed Critical UCB SA
Publication of DE60127845D1 publication Critical patent/DE60127845D1/de
Application granted granted Critical
Publication of DE60127845T2 publication Critical patent/DE60127845T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60127845T 2000-08-31 2001-08-30 Benzylidenthiazolidindione und ihre verwendung als antimykotische mittel Expired - Lifetime DE60127845T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0021421.3A GB0021421D0 (en) 2000-08-31 2000-08-31 Compounds
GB0021421 2000-08-31
PCT/GB2001/003862 WO2002017915A1 (en) 2000-08-31 2001-08-30 Benzylidene thiazolidinediones and their use as antimycotic agents

Publications (2)

Publication Number Publication Date
DE60127845D1 true DE60127845D1 (de) 2007-05-24
DE60127845T2 DE60127845T2 (de) 2007-12-20

Family

ID=9898616

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60127845T Expired - Lifetime DE60127845T2 (de) 2000-08-31 2001-08-30 Benzylidenthiazolidindione und ihre verwendung als antimykotische mittel

Country Status (9)

Country Link
US (1) US7105554B2 (de)
EP (1) EP1313471B1 (de)
JP (1) JP2004507501A (de)
AT (1) ATE359073T1 (de)
AU (1) AU2001284190A1 (de)
DE (1) DE60127845T2 (de)
ES (1) ES2282283T3 (de)
GB (1) GB0021421D0 (de)
WO (1) WO2002017915A1 (de)

Families Citing this family (23)

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GB0204252D0 (en) * 2002-02-23 2002-04-10 Oxford Glycosciences Uk Ltd Novel compounds
WO2003070238A1 (en) * 2002-02-23 2003-08-28 Oxford Glycosciences (Uk) Ltd Thiazolidine antifungal agents
AP2315A (en) 2004-03-23 2011-11-04 Pfizer Formamide derivatives useful as adrenoceptor.
AU2006316838B2 (en) 2005-11-15 2012-04-12 Glycofi, Inc Production of glycoproteins with reduced O-glycosylation
US7731106B2 (en) * 2006-01-04 2010-06-08 Nano Mist International, Llc Air driven delivery system for sprayable media
US8637435B2 (en) * 2007-11-16 2014-01-28 Merck Sharp & Dohme Corp. Eukaryotic cell display systems
JP5731827B2 (ja) * 2008-03-03 2015-06-10 グライコフィ， インコーポレイテッド 下等真核生物中での組換えタンパク質の表面ディスプレイ
AU2009249314A1 (en) 2008-05-20 2009-11-26 Merck Sharp & Dohme Corp. Efficient production of heterologous proteins using mannosyl transferase inhibitors
US8067339B2 (en) * 2008-07-09 2011-11-29 Merck Sharp & Dohme Corp. Surface display of whole antibodies in eukaryotes
JP2011530311A (ja) 2008-08-12 2011-12-22 グライコフィ， インコーポレイテッド タンパク質製造のための改良されたベクターおよび酵母株：Ｃａ２＋ＡＴＰアーゼ過剰発現
JP2014518608A (ja) 2011-02-25 2014-08-07 メルク・シャープ・アンド・ドーム・コーポレーション 修飾ｏ−グリコシル化を有するタンパク質の製造のための酵母株
AU2012291133A1 (en) * 2011-07-29 2014-02-20 Taisho Pharmaceutical Co., Ltd. Amidine compound or salt thereof
WO2014024897A1 (ja) * 2012-08-06 2014-02-13 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 チアゾリジンジオンおよびピロリジンジオン誘導体、並びにそれらを有効成分としてなる殺菌剤
US9261497B2 (en) 2012-10-16 2016-02-16 New York University Method of treating cancer with modulators of SCFSkp2
BR112015032695A2 (pt) 2013-07-04 2017-10-24 Glykos Finland Oy células de fungos filamentosos deficientes em o-manosiltransferase e métodos de uso das mesmas
CN108064266A (zh) 2014-07-21 2018-05-22 格利科斯芬兰公司 在丝状真菌中具有哺乳动物样n-聚糖的糖蛋白的制备
SG11201811093RA (en) 2016-06-14 2019-01-30 Versitech Ltd Antimicrobial compounds and methods for use thereof
WO2017223473A1 (en) * 2016-06-24 2017-12-28 Ohio University Glucose transport inhibitors and methods of using same
RU2662153C1 (ru) * 2017-04-20 2018-07-24 Общество С Ограниченной Ответственностью "Дермавитал Групп" Гибридные эфиры на основе производных тиазолидин-2,4-диона и азолов (1н-1,3-имидазола и 1н-1,3,4-триазола) и их применение
RU2690161C1 (ru) * 2018-06-28 2019-05-31 Общество С Ограниченной Ответственностью "Дермавитал Групп" 3,5-Замещенные производные тиазолидин-2,4-диона, обладающие противомикробной активностью
RU2703997C1 (ru) * 2018-12-13 2019-10-23 Общество с ограниченной ответственностью "Л-Био" Гибридные амиды на основе триазола и тиазолидина, обладающие антимикробной активностью
CN112521382A (zh) * 2020-12-14 2021-03-19 西南大学 芦荟大黄素噻唑烷二酮类化合物及其制备方法和应用
WO2024258316A1 (ru) * 2023-06-16 2024-12-19 Общество с ограниченной ответственностью "Л-Био" Новые потенциальные противогрибковые средства на основе тиазолидин-2,4-диона и триазола

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6156175A (ja) * 1984-08-24 1986-03-20 Yamanouchi Pharmaceut Co Ltd ロダニン誘導体およびその製造法
ZA936492B (en) * 1992-09-10 1995-03-02 Lilly Co Eli Compounds useful as hypoglycemic agents and for treating Alzheimer's disease.
DE4318550A1 (de) * 1993-06-04 1994-12-08 Boehringer Mannheim Gmbh Aryliden-4-oxo-2-thioxo-3- thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
JPH08109175A (ja) * 1994-10-07 1996-04-30 Torii Yakuhin Kk チアゾリジン−２−オンエステル誘導体
JPH08109174A (ja) * 1994-10-07 1996-04-30 Torii Yakuhin Kk チアゾリジン−２−オン誘導体
WO2000018746A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Thiazolidine derivatives for the treatment and prevention of metabolic bone disorders
JP2002525362A (ja) * 1998-09-30 2002-08-13 エスヴァイン、アンゲリカ 代謝性骨障害の治療および予防のためのロダニンカルボン酸誘導体
US6506755B2 (en) * 2000-02-03 2003-01-14 Hoffmann-La Roche Inc. Thiazolidinecarboxyl acids

Also Published As

Publication number Publication date
GB0021421D0 (en) 2000-10-18
EP1313471B1 (de) 2007-04-11
DE60127845T2 (de) 2007-12-20
AU2001284190A1 (en) 2002-03-13
US20040006112A1 (en) 2004-01-08
EP1313471A1 (de) 2003-05-28
WO2002017915A1 (en) 2002-03-07
JP2004507501A (ja) 2004-03-11
US7105554B2 (en) 2006-09-12
ATE359073T1 (de) 2007-05-15
ES2282283T3 (es) 2007-10-16

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