DE60121932D1 - Zusammensetzungen zur behandlung von bindegeweben, die ein eisen(ii)-ion und ascorbat enthalten - Google Patents
Zusammensetzungen zur behandlung von bindegeweben, die ein eisen(ii)-ion und ascorbat enthaltenInfo
- Publication number
- DE60121932D1 DE60121932D1 DE60121932T DE60121932T DE60121932D1 DE 60121932 D1 DE60121932 D1 DE 60121932D1 DE 60121932 T DE60121932 T DE 60121932T DE 60121932 T DE60121932 T DE 60121932T DE 60121932 D1 DE60121932 D1 DE 60121932D1
- Authority
- DE
- Germany
- Prior art keywords
- ascorbate
- treatment
- compositions
- ion
- weaves
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title abstract 7
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 229940072107 ascorbate Drugs 0.000 title abstract 4
- 235000010323 ascorbic acid Nutrition 0.000 title abstract 4
- 239000011668 ascorbic acid Substances 0.000 title abstract 4
- RFBYLSCVRUTUSB-ZZMNMWMASA-L (2r)-2-[(1s)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2h-furan-4-olate;iron(2+) Chemical compound [Fe+2].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] RFBYLSCVRUTUSB-ZZMNMWMASA-L 0.000 title 1
- 229910001448 ferrous ion Inorganic materials 0.000 abstract 3
- 201000008482 osteoarthritis Diseases 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- CBOJBBMQJBVCMW-BTVCFUMJSA-N (2r,3r,4s,5r)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride Chemical compound Cl.O=C[C@H](N)[C@@H](O)[C@H](O)[C@H](O)CO CBOJBBMQJBVCMW-BTVCFUMJSA-N 0.000 abstract 1
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 abstract 1
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 230000022159 cartilage development Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229960002442 glucosamine Drugs 0.000 abstract 1
- 150000002301 glucosamine derivatives Chemical class 0.000 abstract 1
- 229960001911 glucosamine hydrochloride Drugs 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Removal Of Specific Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20036100P | 2000-04-28 | 2000-04-28 | |
| PCT/CA2001/000564 WO2001082938A2 (en) | 2000-04-28 | 2001-04-25 | Compositions useful in the treatment of diseases of connective tissues comprising a ferrous ion and an ascorbate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60121932D1 true DE60121932D1 (de) | 2006-09-14 |
Family
ID=22741396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60121932T Expired - Lifetime DE60121932D1 (de) | 2000-04-28 | 2001-04-25 | Zusammensetzungen zur behandlung von bindegeweben, die ein eisen(ii)-ion und ascorbat enthalten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6632804B2 (de) |
| EP (1) | EP1276485B1 (de) |
| JP (1) | JP2003531858A (de) |
| AT (1) | ATE334690T1 (de) |
| AU (1) | AU2001254556A1 (de) |
| CA (1) | CA2343439C (de) |
| DE (1) | DE60121932D1 (de) |
| WO (1) | WO2001082938A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7851458B2 (en) * | 1999-06-22 | 2010-12-14 | Joint Juice, Inc. | Cartilage enhancing food supplements and methods of preparing the same |
| ES2190379B1 (es) * | 2001-12-21 | 2004-11-16 | Bioiberica,S.A | Procedimiento de preparacion de sales de glucosamina. |
| US8455458B2 (en) * | 2002-10-16 | 2013-06-04 | Arthrodynamic Technologies, Animal Health Division, Inc. | Composition and method for treating connective tissue damage |
| US20080003258A1 (en) * | 2002-10-16 | 2008-01-03 | Marcum Frank D | Composition and Method for Treating Rheumatoid Arthritis |
| US7803787B2 (en) * | 2002-10-16 | 2010-09-28 | Arthrodynamic Technologies, Animal Health Division, Inc. | Composition and method for treating connective tissue damage by transmucosal administration |
| US20040086581A1 (en) * | 2002-11-06 | 2004-05-06 | Jones Edwin B. | Bio-energetic joint and arthritis pain formula |
| CN1232256C (zh) * | 2003-03-27 | 2005-12-21 | 中国人民解放军第三军医大学 | N－乙酰氨基葡萄糖在制备治疗自身免疫反应所致的局部损伤或全身症状的药物中的应用 |
| US8633246B2 (en) * | 2003-08-11 | 2014-01-21 | Hill's Pet Nutrition, Inc. | Omega-3 fatty acids for osteoarthritis |
| US8633247B2 (en) * | 2003-08-11 | 2014-01-21 | Hill's Pet Nutrition, Inc. | Method for decreasing cartilage damage in dogs |
| ES2255829B1 (es) * | 2004-08-06 | 2007-08-16 | Bioiberica, S.A. | Nuevo uso de sales de glucosamina. |
| CA2603518C (en) * | 2005-04-13 | 2013-11-26 | Snow Brand Milk Products Co., Ltd. | Nutrient composition for promoting collagen production |
| DE102005020327A1 (de) | 2005-04-30 | 2006-11-09 | Multibind Biotec Gmbh | Dekontaminationslösungen und deren Verwendung zur Denaturierung, Modifikation, Degradation, Solubilisierung und Entfernung von Proteinen, Nukleinsäuremolekülen und Mikroorganismen von Oberflächen |
| DE102006001213A1 (de) * | 2006-01-10 | 2007-07-12 | Multibind Biotec Gmbh | Synergistische Lösung aus Ascobinsäure oder deren Derivaten und Metallionen effizienten, selektiven Abtötung pathologischer Säugerzellen |
| WO2007143660A1 (en) * | 2006-06-05 | 2007-12-13 | Stokely-Van Camp, Inc. | Reducing muscle soreness with glucosamine compositions |
| US9186375B2 (en) | 2007-06-21 | 2015-11-17 | Arthrodynamic Technologies, Animal Health Division, Inc. | Glycosaminoglycan compositions in combination with stem cells |
| BE1019135A5 (nl) * | 2010-01-08 | 2012-03-06 | Lab Smeets Nv | Voedingssupplement bevattende glucosamine. |
| US10143219B2 (en) * | 2013-03-06 | 2018-12-04 | Rutgers, The State University Of New Jersey | Nutritional supplement/feed formula and methods of use thereof to reduce development of Osteochondrosis Dissecans (OCD) lesions |
| EP2886104A1 (de) | 2013-12-11 | 2015-06-24 | Patir, Suleyman | Intraartikuläres Gel |
| CN108883056A (zh) * | 2015-12-30 | 2018-11-23 | 亚历山大·维莱诺维奇·阿萨福夫 | 用于治疗外周关节、脊柱关节和/或结缔组织的细胞外基质元件的制剂、制造方法和用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2822317A (en) * | 1955-12-12 | 1958-02-04 | Smith Kline French Lab | Aqueous iron-ascorbic acid preparation |
| IT1044707B (it) | 1968-10-26 | 1980-04-21 | Rotta Research Lab | Procedimento per la preparazione di sali di glucosanina e preparati farmaceutici comprendenti detti sali di glucosamina come agenti attivi |
| NZ194947A (en) | 1979-09-18 | 1983-06-14 | C Holland | Composition containing calcium and ferrous ions for treatment of rheumatoid arthritis |
| WO1985000033A1 (fr) * | 1983-06-18 | 1985-01-03 | Japan As Represented By Director-General Of Agency | Solution aqueuse chimiquement active et substance solide contenant des ions ferreux |
| US5405613A (en) * | 1991-12-11 | 1995-04-11 | Creative Nutrition Canada Corp. | Vitamin/mineral composition |
| US5364845C1 (en) | 1993-03-31 | 2002-09-10 | Nutramax Lab Inc | Glusosamine chondroitin and manganese composition for the protection and repair of connective tissue |
| AT408416B (de) | 1996-07-19 | 2001-11-26 | Norbert Fuchs | Pharmazeutische bzw. diätetische zusammensetzungen |
| GB2317109B (en) | 1996-08-28 | 2000-06-21 | Farmsense | A therapeutic composition for the treatment and repair of connective tissue in mammals |
| GB9621273D0 (en) | 1996-10-11 | 1996-11-27 | Cortecs Ltd | Therapeutic method |
| US6245360B1 (en) * | 1998-06-26 | 2001-06-12 | John S. Markowitz | Nutritional supplement |
| US6177476B1 (en) * | 1998-08-27 | 2001-01-23 | Clarion Pharmaceuticals Inc. | Nutritional supplements for replenishing plasmalogens |
| DE20004010U1 (de) * | 2000-03-02 | 2000-06-21 | Febena Pharma GmbH, 50825 Köln | Diätische Zusammensetzung mit einem Gehalt an Glycosaminoglycanen |
-
2001
- 2001-04-25 DE DE60121932T patent/DE60121932D1/de not_active Expired - Lifetime
- 2001-04-25 JP JP2001579812A patent/JP2003531858A/ja active Pending
- 2001-04-25 AU AU2001254556A patent/AU2001254556A1/en not_active Abandoned
- 2001-04-25 US US09/842,742 patent/US6632804B2/en not_active Expired - Fee Related
- 2001-04-25 CA CA002343439A patent/CA2343439C/en not_active Expired - Fee Related
- 2001-04-25 EP EP01927527A patent/EP1276485B1/de not_active Expired - Lifetime
- 2001-04-25 WO PCT/CA2001/000564 patent/WO2001082938A2/en active IP Right Grant
- 2001-04-25 AT AT01927527T patent/ATE334690T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE334690T1 (de) | 2006-08-15 |
| AU2001254556A1 (en) | 2001-11-12 |
| CA2343439C (en) | 2003-06-24 |
| US6632804B2 (en) | 2003-10-14 |
| EP1276485B1 (de) | 2006-08-02 |
| EP1276485A2 (de) | 2003-01-22 |
| US20010044425A1 (en) | 2001-11-22 |
| WO2001082938A3 (en) | 2002-08-08 |
| CA2343439A1 (en) | 2001-07-09 |
| JP2003531858A (ja) | 2003-10-28 |
| WO2001082938A2 (en) | 2001-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |