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DE60118956D1 - Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen - Google Patents

Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen

Info

Publication number
DE60118956D1
DE60118956D1 DE60118956T DE60118956T DE60118956D1 DE 60118956 D1 DE60118956 D1 DE 60118956D1 DE 60118956 T DE60118956 T DE 60118956T DE 60118956 T DE60118956 T DE 60118956T DE 60118956 D1 DE60118956 D1 DE 60118956D1
Authority
DE
Germany
Prior art keywords
treatment
pain
type
calcium channel
channel antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60118956T
Other languages
English (en)
Other versions
DE60118956T2 (de
Inventor
Bipinchandra Chaudhari
Marc Chapdelaine
Greg Hostetler
Lucius Kemp
John Mccauley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of DE60118956D1 publication Critical patent/DE60118956D1/de
Application granted granted Critical
Publication of DE60118956T2 publication Critical patent/DE60118956T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60118956T 2000-11-06 2001-10-31 Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen Expired - Fee Related DE60118956T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0004053 2000-11-06
SE0004053A SE0004053D0 (sv) 2000-11-06 2000-11-06 N-type calcium channel antagonists for the treatment of pain
PCT/SE2001/002388 WO2002036586A1 (en) 2000-11-06 2001-10-31 N-type calcium channel antagonists for the treatment of pain

Publications (2)

Publication Number Publication Date
DE60118956D1 true DE60118956D1 (de) 2006-05-24
DE60118956T2 DE60118956T2 (de) 2007-03-15

Family

ID=20281713

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60118956T Expired - Fee Related DE60118956T2 (de) 2000-11-06 2001-10-31 Calciumkanalantagonisten vom n-typ zur behandlung von schmerzen

Country Status (9)

Country Link
US (1) US6815447B2 (de)
EP (1) EP1339706B1 (de)
JP (1) JP2004513125A (de)
AT (1) ATE323693T1 (de)
AU (1) AU2002212894A1 (de)
DE (1) DE60118956T2 (de)
ES (1) ES2261496T3 (de)
SE (1) SE0004053D0 (de)
WO (1) WO2002036586A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040259866A1 (en) * 1998-06-30 2004-12-23 Snutch Terrance P. Calcium channel blockers comprising two benzhydril moieties
CA2486376A1 (en) 2002-05-22 2003-12-04 Amgen Inc. Amino-pyridine, -pyridine and pyridazine derivatives for use as vanilloid receptor ligands for the treatment of pain
AR041191A1 (es) 2002-08-08 2005-05-04 Amgen Inc Ligandos del receptor vanilloide y su uso en tratamientos
US7419984B2 (en) * 2002-10-17 2008-09-02 Cell Therapeutics, Inc. Pyrimidines and uses thereof
ES2375111T3 (es) 2002-11-21 2012-02-24 Novartis Ag Pirimidinas 2,4,6-trisustituidas como inhibidores de fosfotidilinositol (pi) 3-quinasa y su uso en el tratamiento de c�?ncer.
JP4691041B2 (ja) * 2003-11-20 2011-06-01 チルドレンズ ホスピタル メディカル センター Gtpアーゼ阻害剤および使用方法
US7301022B2 (en) 2005-02-15 2007-11-27 Amgen Inc. Vanilloid receptor ligands and their use in treatments
US20080300262A1 (en) * 2005-04-08 2008-12-04 Snutch Terrance P Combination Therapy for Relief of Pain
JO2660B1 (en) 2006-01-20 2012-06-17 نوفارتيس ايه جي Pi-3 inhibitors and methods of use
WO2007133481A2 (en) * 2006-05-11 2007-11-22 Neuromed Pharmaceuticals Ltd. Method for increasing the bioavailability of benzhydryl piperazine containing compounds
KR20090108124A (ko) 2007-02-06 2009-10-14 노파르티스 아게 Pi 3-키나제 억제제 및 그의 사용 방법
PT2542084T (pt) * 2010-03-04 2018-03-23 Merck Sharp & Dohme Inibidores de catecol o-metil transferase e sua utilização no tratamento de distúrbios psicóticos
EP2542076B1 (de) 2010-03-04 2021-01-13 Merck Sharp & Dohme Corp. Hemmer der catechol-o-methyl-transferase und ihre verwendung bei der behandlung psychotischer störungen
US9309199B2 (en) 2010-03-04 2016-04-12 Merck Sharp & Dohme Corp. Inhibitors of catechol O-methyl transferase and their use in the treatment of psychotic disorders
US8409560B2 (en) 2011-03-08 2013-04-02 Zalicus Pharmaceuticals Ltd. Solid dispersion formulations and methods of use thereof
KR20140011366A (ko) 2011-03-08 2014-01-28 잘리커스 파마슈티컬즈 리미티드 고체 분산체 제형 및 그의 이용방법
CU24269B1 (es) 2011-09-27 2017-08-08 Novartis Ag 3- pirimidin- 4-il- oxazolidin- 2- onas inhibidores de la idh mutante
UY34632A (es) 2012-02-24 2013-05-31 Novartis Ag Compuestos de oxazolidin- 2- ona y usos de los mismos
US9296733B2 (en) 2012-11-12 2016-03-29 Novartis Ag Oxazolidin-2-one-pyrimidine derivative and use thereof for the treatment of conditions, diseases and disorders dependent upon PI3 kinases
AP2015008707A0 (en) 2013-03-14 2015-09-30 Novartis Ag 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB794043A (en) * 1955-06-03 1958-04-30 Ici Ltd New quinoline derivatives
IL138573A0 (en) 1998-03-26 2001-10-31 Japan Tobacco Inc Amide derivatives and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
WO2002036586A1 (en) 2002-05-10
EP1339706B1 (de) 2006-04-19
US20040058945A1 (en) 2004-03-25
DE60118956T2 (de) 2007-03-15
SE0004053D0 (sv) 2000-11-06
EP1339706A1 (de) 2003-09-03
ATE323693T1 (de) 2006-05-15
AU2002212894A1 (en) 2002-05-15
JP2004513125A (ja) 2004-04-30
US6815447B2 (en) 2004-11-09
ES2261496T3 (es) 2006-11-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee