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DE60118859D1 - Pharmazeutische Zusammensetzung enthaltend Trehalose zur ophthalmischen Verwendung - Google Patents

Pharmazeutische Zusammensetzung enthaltend Trehalose zur ophthalmischen Verwendung

Info

Publication number
DE60118859D1
DE60118859D1 DE60118859T DE60118859T DE60118859D1 DE 60118859 D1 DE60118859 D1 DE 60118859D1 DE 60118859 T DE60118859 T DE 60118859T DE 60118859 T DE60118859 T DE 60118859T DE 60118859 D1 DE60118859 D1 DE 60118859D1
Authority
DE
Germany
Prior art keywords
pharmaceutical composition
composition containing
ophthalmic use
containing trehalose
trehalose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60118859T
Other languages
English (en)
Other versions
DE60118859T2 (de
Inventor
Toshihiko Matsuo
Masashi Kurimoto
Hiroshi Yamauchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hayashibara Seibutsu Kagaku Kenkyujo KK
Original Assignee
Hayashibara Seibutsu Kagaku Kenkyujo KK
Hayashibara Biochemical Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hayashibara Seibutsu Kagaku Kenkyujo KK, Hayashibara Biochemical Laboratories Co Ltd filed Critical Hayashibara Seibutsu Kagaku Kenkyujo KK
Application granted granted Critical
Publication of DE60118859D1 publication Critical patent/DE60118859D1/de
Publication of DE60118859T2 publication Critical patent/DE60118859T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE60118859T 2000-09-14 2001-08-30 Pharmazeutische Zusammensetzung enthaltend Trehalose zur ophthalmischen Verwendung Expired - Lifetime DE60118859T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000280023 2000-09-14
JP2000280023 2000-09-14

Publications (2)

Publication Number Publication Date
DE60118859D1 true DE60118859D1 (de) 2006-05-24
DE60118859T2 DE60118859T2 (de) 2006-11-23

Family

ID=18764933

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60118859T Expired - Lifetime DE60118859T2 (de) 2000-09-14 2001-08-30 Pharmazeutische Zusammensetzung enthaltend Trehalose zur ophthalmischen Verwendung
DE60138495T Expired - Lifetime DE60138495D1 (de) 2000-09-14 2001-08-30 Pharmazeutische Zusammensetzung Trehalose zur ophthalmischen Verwendung enthaltend

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60138495T Expired - Lifetime DE60138495D1 (de) 2000-09-14 2001-08-30 Pharmazeutische Zusammensetzung Trehalose zur ophthalmischen Verwendung enthaltend

Country Status (7)

Country Link
US (2) US6555526B2 (de)
EP (2) EP1649860B1 (de)
KR (1) KR100776124B1 (de)
AU (1) AU781975B2 (de)
CA (1) CA2355814C (de)
DE (2) DE60118859T2 (de)
TW (1) TWI291350B (de)

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US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
PL373780A1 (en) 2002-02-25 2005-09-19 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
JP2005008596A (ja) * 2003-06-20 2005-01-13 Kobayashi Pharmaceut Co Ltd 眼科用組成物
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US8569367B2 (en) 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
CN101123948A (zh) * 2005-02-17 2008-02-13 千寿制药株式会社 眼科用固体外用药剂
CN104840455A (zh) 2005-02-24 2015-08-19 扩散药品有限公司 反式类胡萝卜素、其合成、制剂和用途
US8288348B2 (en) * 2005-07-13 2012-10-16 Allergan, Inc. Cyclosporin compositions
WO2007047242A2 (en) * 2005-10-14 2007-04-26 Soll David B Ophthalmic surgical irrigating solutions containing hyaluronidase
US20070207116A1 (en) * 2006-03-01 2007-09-06 Brown David C Antioxidant compositions for the eye
US9539202B2 (en) * 2006-04-28 2017-01-10 Universidad Complutense De Madrid Formulation of liposomal vesicles in aqueous solutions with lachrymal film characteristics
JP4668875B2 (ja) * 2006-09-20 2011-04-13 株式会社日立製作所 番組録画再生装置、番組再生位置制御方法及び番組情報提供装置
WO2008136900A1 (en) * 2007-04-13 2008-11-13 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease
US8206751B2 (en) * 2007-10-31 2012-06-26 Diffusion Pharmaceuticals Llc Class of therapeutics that enhance small molecule diffusion
WO2010085323A1 (en) * 2009-01-20 2010-07-29 Advanced Vision Research, Inc. Methods and compositions for the treatment and prevention of infections
CN102458110A (zh) 2009-06-22 2012-05-16 扩散药品有限公司 扩散促进化合物及其单独或与溶栓药一起的应用
WO2011152869A1 (en) 2010-06-02 2011-12-08 Diffusion Pharmaceuticals Llc Oral formulations of bipolar trans carotenoids
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
DK2787968T3 (da) 2011-12-07 2020-06-02 Allergan Inc Effektiv lipidlevering til menneskelig tårefilm under anvendelse af et saltsensitivt emulsionssystem
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
EP2807177B1 (de) 2012-01-27 2019-11-13 The Regents of The University of California Stabilisierung von biomolekülen anhand von zuckerpolymeren
WO2014081969A1 (en) * 2012-11-21 2014-05-30 University Of Louisville Research Foundation, Inc Compositions and methods for reducing oxidative damage
US9084720B2 (en) 2013-05-07 2015-07-21 BioBlast Pharma Ltd. Compositions and methods for treating oculopharyngeal muscular dystrophy
MX2015015355A (es) 2013-05-07 2016-07-18 Bio Blast Pharma Ltd Tratamiento de enfermedades miopaticas y neurodegenerativas por agregacion de proteina mediante administracion parenteral.
US9180208B2 (en) * 2013-09-25 2015-11-10 i SONIC Medical Corporation Composition and methods for enhancing surface reflectance
US10350232B1 (en) * 2013-11-04 2019-07-16 Peter D. Jaillet Medicinal drops
KR101587412B1 (ko) * 2014-10-17 2016-01-21 주식회사 휴온스 사이클로스포린 및 트레할로스를 포함하는 안과용 조성물
KR102487299B1 (ko) 2014-11-25 2023-01-10 알러간, 인코포레이티드 안정화된 오메가-3 안과용 조성물
CA3014030C (en) 2015-02-09 2023-10-03 Ori Braun Ophthalmic compositions and methods for reducing oxidative damage to an eye lens
KR102489034B1 (ko) 2016-03-24 2023-01-13 디퓨젼 파마슈티컬즈 엘엘씨 암을 치료하기 위한, 화학 요법 및 방사선 요법과의 양극성 트랜스 카로티노이드의 용도
KR102268319B1 (ko) * 2016-12-29 2021-06-23 (주)휴온스 지속성 점안제 조성물
EP3996671A1 (de) 2019-07-12 2022-05-18 Pharmathen S.A. Konservierungsmittelfreie pharmazeutische zusammensetzung mit cyclosporin zur ophthalmischen verabreichung
GR1010012B (el) 2020-05-12 2021-05-27 Φαρματεν Α.Β.Ε.Ε. Φαρμακευτικο σκευασμα ελευθερο συντηρητικου για οφθαλμικη χορηγηση περιεχον κυκλοσπορινη
WO2024246753A1 (en) 2023-05-29 2024-12-05 Technophage, Investigação E Desenvolvimento Em Biotecnologia, S.A. Ophthalmic compositions

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* Cited by examiner, † Cited by third party
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JP3082094B2 (ja) 1990-11-15 2000-08-28 株式会社林原生物化学研究所 ネオトレハロースの製造方法とその用途
ES2136115T3 (es) 1992-12-28 1999-11-16 Hayashibara Biochem Lab Enzima formadora de sacaridos no reductores, y su preparacion y usos.
JP3418423B2 (ja) * 1993-03-03 2003-06-23 久光製薬株式会社 経粘膜投与用薬剤組成物
JP3559585B2 (ja) 1993-06-03 2004-09-02 株式会社林原生物化学研究所 トレハロース遊離酵素とその製造方法並びに用途
DK0674005T3 (da) 1994-02-23 1999-12-13 Hayashibara Biochem Lab Ikke-reducerende sacchariddannende enzym, DNA, som koder for det, samt fremstilling og anvendelse deraf
JP3557272B2 (ja) 1994-02-23 2004-08-25 株式会社林原生物化学研究所 組換え型酵素とその製造方法並びに用途
DE69532485T2 (de) 1994-03-07 2004-11-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung
JP3559609B2 (ja) 1994-03-07 2004-09-02 株式会社林原生物化学研究所 組換え型酵素とその製造方法並びに用途
JP3557277B2 (ja) 1994-06-25 2004-08-25 株式会社林原生物化学研究所 耐熱性トレハロース遊離酵素とその製造方法並びに用途
AU695080B2 (en) 1994-06-24 1998-08-06 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Thermostable non-reducing saccharide-forming enzyme, its production and uses
JP3557287B2 (ja) 1994-06-24 2004-08-25 株式会社林原生物化学研究所 耐熱性非還元性糖質生成酵素とその製造方法並びに用途
JP3557289B2 (ja) 1994-07-21 2004-08-25 株式会社林原生物化学研究所 非還元性糖質からトレハロースを遊離する組換え型耐熱性酵素
JP3557288B2 (ja) 1994-07-21 2004-08-25 株式会社林原生物化学研究所 還元性澱粉糖から末端にトレハロース構造を有する非還元性糖質を生成する組換え型耐熱性酵素
JP4033510B2 (ja) * 1995-12-27 2008-01-16 ロート製薬株式会社 トレハロースを含有する眼科用医薬組成物
WO1997024129A1 (en) * 1995-12-27 1997-07-10 Rohto Pharmaceutical Co., Ltd. Pharmaceutical composition containing trehalose
JPH09227385A (ja) * 1996-02-29 1997-09-02 Ofutekusu:Kk 眼手術用補助剤
JPH1072376A (ja) * 1996-09-02 1998-03-17 Ofutekusu:Kk ヒアルロン酸含有点眼水溶液
JP4203159B2 (ja) * 1997-12-09 2008-12-24 株式会社林原生物化学研究所 神経機能調節剤
AU2001253137A1 (en) * 2000-04-04 2001-10-15 Amarillo Biosciences, Inc. Composition and method for promoting oral health

Also Published As

Publication number Publication date
AU6545301A (en) 2002-03-21
CA2355814C (en) 2010-06-29
US20030186931A1 (en) 2003-10-02
DE60118859T2 (de) 2006-11-23
EP1649860A1 (de) 2006-04-26
EP1192947A1 (de) 2002-04-03
US20020055486A1 (en) 2002-05-09
KR20020021320A (ko) 2002-03-20
US6555526B2 (en) 2003-04-29
US7732425B2 (en) 2010-06-08
DE60138495D1 (de) 2009-06-04
KR100776124B1 (ko) 2007-11-15
AU781975B2 (en) 2005-06-23
TWI291350B (en) 2007-12-21
EP1192947B1 (de) 2006-04-19
CA2355814A1 (en) 2002-03-14
EP1649860B1 (de) 2009-04-22

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Legal Events

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