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DE60118743D1 - Methode zur behandlung und prävention von ansteckenden krankheiten - Google Patents

Methode zur behandlung und prävention von ansteckenden krankheiten

Info

Publication number
DE60118743D1
DE60118743D1 DE60118743T DE60118743T DE60118743D1 DE 60118743 D1 DE60118743 D1 DE 60118743D1 DE 60118743 T DE60118743 T DE 60118743T DE 60118743 T DE60118743 T DE 60118743T DE 60118743 D1 DE60118743 D1 DE 60118743D1
Authority
DE
Germany
Prior art keywords
lipid
infectious
infectious organism
present
infectious diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60118743T
Other languages
English (en)
Other versions
DE60118743T2 (de
Inventor
Bill E Cham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Lipid Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/AU2000/001603 external-priority patent/WO2001045718A1/en
Application filed by Lipid Sciences Inc filed Critical Lipid Sciences Inc
Application granted granted Critical
Publication of DE60118743D1 publication Critical patent/DE60118743D1/de
Publication of DE60118743T2 publication Critical patent/DE60118743T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088Liquid substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10161Methods of inactivation or attenuation
    • C12N2730/10163Methods of inactivation or attenuation by chemical treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361Methods of inactivation or attenuation
    • C12N2770/24363Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • AIDS & HIV (AREA)
DE60118743T 2000-06-29 2001-06-21 Methode zur behandlung und prävention von ansteckenden krankheiten Expired - Lifetime DE60118743T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AUPQ8469A AUPQ846900A0 (en) 2000-06-29 2000-06-29 A vaccine
AUPQ846900 2000-06-29
WOPCT/AU00/01603 2000-12-28
PCT/AU2000/001603 WO2001045718A1 (en) 1999-12-23 2000-12-28 A method of treating infectious diseases
PCT/IB2001/001099 WO2002000266A2 (en) 2000-06-29 2001-06-21 A method of treating and preventing infectious diseases

Publications (2)

Publication Number Publication Date
DE60118743D1 true DE60118743D1 (de) 2006-05-24
DE60118743T2 DE60118743T2 (de) 2006-10-26

Family

ID=3822536

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60118743T Expired - Lifetime DE60118743T2 (de) 2000-06-29 2001-06-21 Methode zur behandlung und prävention von ansteckenden krankheiten

Country Status (11)

Country Link
US (3) US20030133929A1 (de)
EP (1) EP1299130B1 (de)
JP (2) JP4852219B2 (de)
AT (1) ATE322914T1 (de)
AU (4) AUPQ846900A0 (de)
CA (1) CA2412503A1 (de)
DE (1) DE60118743T2 (de)
DK (1) DK1299130T3 (de)
ES (1) ES2261420T3 (de)
PT (1) PT1299130E (de)
WO (1) WO2002000266A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8197430B1 (en) * 1998-05-22 2012-06-12 Biopheresis Technologies, Inc. Method and system to remove cytokine inhibitor in patients
US6620382B1 (en) 1998-05-22 2003-09-16 Biopheresis Technologies, Llc. Method and compositions for treatment of cancers
US6379708B1 (en) * 1999-11-20 2002-04-30 Cytologic, Llc Method for enhancing immune responses in mammals
AUPQ846900A0 (en) * 2000-06-29 2000-07-27 Aruba International Pty Ltd A vaccine
US7439052B2 (en) * 2000-06-29 2008-10-21 Lipid Sciences Method of making modified immunodeficiency virus particles
US7407662B2 (en) 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content
US20090017069A1 (en) * 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
US7407663B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified immunodeficiency virus particles
EP1567188B1 (de) * 2003-06-20 2012-07-11 Eli Lilly And Company Modifizierte virusteilchen mit immunogeneneigenschaften und verringertem lipidgehalt zur behandlung und prävention von infektionskrankheiten
US7393826B2 (en) 2003-07-03 2008-07-01 Lipid Sciences, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
DE102004003572A1 (de) * 2004-01-23 2005-08-18 Bavarian Nordic A/S Monoparamunitätsinducer basierend auf attenuierten Myxomaviren des Kaninchens
AU2005240082B2 (en) * 2004-04-30 2009-07-23 Innatus Corporation Method and system to remove soluble TNFR1,TNFR2, and IL2 in patients
EP1859656B1 (de) * 2004-12-30 2013-07-17 E.I. Du Pont De Nemours And Company Organometallische komplexe
EP1917029B1 (de) * 2005-07-27 2013-01-23 Eli Lilly And Company Verfahren zur behandlung von krebszellen zur erzeugung einer modifizierten krebszelle, die eine immunogene antwort auslöst
US20070065514A1 (en) * 2005-09-22 2007-03-22 Howell Mark D Method for enhancing immune responses in mammals
US20070128693A1 (en) * 2005-12-06 2007-06-07 Advantek Serum Laboratories Limited3/F Method for the inactivation and removal of dengue virus from biological samples
US20080075690A1 (en) * 2006-09-22 2008-03-27 Mark Douglas Howell Method for enhancing immune responses in mammals
US9278999B2 (en) * 2012-01-27 2016-03-08 Newport Laboratories Influenza C virus and vaccine
EP3170509A4 (de) 2014-07-18 2017-12-27 The Chemo-Sero-Therapeutic Research Institute Impfstoff mit virusähnlichen partikeln
US9815886B2 (en) 2014-10-28 2017-11-14 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
AR107262A1 (es) 2016-01-27 2018-04-11 Lilly Co Eli Inactivación de patógenos por delipidación
US11027052B2 (en) 2017-11-22 2021-06-08 HDL Therapuetics, Inc. Systems and methods for priming fluid circuits of a plasma processing system
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
AU2018396009A1 (en) 2017-12-28 2020-07-16 Hdl Therapeutics, Inc. Methods for preserving and administering pre-beta high density lipoprotein extracted from human plasma
CN109964875B (zh) * 2019-04-04 2021-10-01 中国农业科学院北京畜牧兽医研究所 一种生产抗3型鸭甲肝病毒和屠体性能高的肉鸭配套方法

Family Cites Families (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3647624A (en) * 1969-07-24 1972-03-07 Wisconsin Alumni Res Found Treatment of blood with oleaginous substance
US3989466A (en) * 1973-08-13 1976-11-02 Pan Samuel C Liquid-liquid extraction apparatus including fibrous strand packing
JPS5328989B2 (de) * 1974-05-27 1978-08-17
US3958939A (en) * 1975-01-08 1976-05-25 Coulter Electronics, Inc. Method for clarification of lipemic serum
DE2501376A1 (de) * 1975-01-15 1976-07-22 Metallgesellschaft Ag Verfahren zur entfernung von mono- und diphenolen und dergleichen aus abwaessern
US4258010A (en) * 1975-11-19 1981-03-24 Eszakmagyarorszagi Vegyimu_ vek Solvent extraction apparatus
JPS5272379A (en) * 1975-12-15 1977-06-16 Toray Ind Inc Separation of fluid
US4103685A (en) * 1976-01-05 1978-08-01 Lupien Paul J Method and apparatus for extravascular treatment of blood
US4671909A (en) * 1978-09-21 1987-06-09 Torobin Leonard B Method for making hollow porous microspheres
US4424131A (en) * 1978-12-18 1984-01-03 Artisan Industries Inc. Liquid-liquid extraction method and apparatus
FR2455743A1 (fr) * 1979-05-02 1980-11-28 Goella Laboratoires Procede et dispositif pour le dosage des lipoproteines seriques
FR2475572A1 (fr) * 1980-02-11 1981-08-14 Pasteur Institut Procede pour l'obtention de fragments de virus a enveloppe lipidique, en particulier d'antigenes utilisables comme vaccins, produits obtenus et applications
EP0036283A3 (de) * 1980-03-19 1982-03-31 DAVY MCKEE (MINERALS & METALS) LIMITED Verfahren und Vorrichtung für die Flüssig-flüssig-Extraktion
US4350156A (en) * 1980-05-29 1982-09-21 Japan Foundation For Artificial Organs Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid
EP0074610B1 (de) * 1981-09-10 1987-05-20 Intermedicat GmbH Verfahren zur selektiven extrakorporalen Präzipitation von Low Density Lipoproteinen aus Vollserum oder Plasma
US4435289A (en) * 1981-12-23 1984-03-06 Romicon, Inc. Series ultrafiltration with pressurized permeate
JPS58155865A (ja) * 1982-03-12 1983-09-16 株式会社クラレ 血漿処理用中空糸膜
US4591505A (en) * 1982-04-14 1986-05-27 New York Blood Center, Inc. Process for inactivating hepatitis B virus
US4431633A (en) * 1982-04-27 1984-02-14 Merck & Co., Inc. Influenza vaccine
US4581231A (en) * 1982-06-10 1986-04-08 The United States Of America As Represented By The Secretary Of Health And Human Services Inactivation of viruses containing essential lipids
US4463988A (en) * 1982-09-07 1984-08-07 Cities Service Co. Horizontal heated plane process
US4643718A (en) * 1983-02-22 1987-02-17 Applied Immunesciences, Inc. Therapeutic apheresis
DE3310727A1 (de) * 1983-03-24 1984-10-04 B. Braun Melsungen Ag, 3508 Melsungen Verfahren und vorrichtung zur selektiven, extrakorporalen abtrennung pathologischer und/oder toxischer blutbestandteile
US4668398A (en) * 1983-07-21 1987-05-26 Colgate-Palmolive Company Continuous extraction apparatus and process
US4615886A (en) * 1983-08-31 1986-10-07 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Utilizing a halohydrocarbon containing dissolved water to inactivate a lipid virus
GB8334564D0 (en) * 1983-12-29 1984-02-01 Carib Agro Ind Ltd Sugar cane harvesters
JPS60231613A (ja) * 1984-04-28 1985-11-18 Terumo Corp T細胞とb細胞の分離方法およびその分離材ならびにその分離装置
DE3422494A1 (de) * 1984-06-16 1985-12-19 B. Braun Melsungen Ag, 3508 Melsungen Verfahren und vorrichtung zur spezifischen adsorption von heparin
DE3422407A1 (de) * 1984-06-16 1986-03-06 B. Braun Melsungen Ag, 3508 Melsungen Verwendung von heparinderivaten zur selektiven extrakorporalen praezipitation von low-density-lipoproteinen aus vollserum oder plasma
EP0168093B1 (de) * 1984-06-27 1988-11-23 Organon Teknika B.V. Binder für Lipoproteine niedriger Dichte
JPS61119271A (ja) * 1984-11-13 1986-06-06 鐘淵化学工業株式会社 血液成分処理回路及び血液成分処理方法
DE3568442D1 (en) * 1984-12-06 1989-04-06 Kanegafuchi Chemical Ind A method of preparation of droplets
US4613501A (en) * 1984-12-21 1986-09-23 New York Blood Center, Inc. Inactivation of viruses in labile blood derivatives
US4677057A (en) * 1985-03-11 1987-06-30 Scripps Clinic And Research Foundation Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins
US4645512A (en) * 1985-05-06 1987-02-24 The Dow Chemical Company Continuous process for removing water-soluble particles from organic liquids
US4895558A (en) * 1985-07-15 1990-01-23 University Of Queensland Autologous plasma delipidation using a continuous flow system
US4605648A (en) * 1985-08-15 1986-08-12 Price E Pendleton Treatment of Herpes Simplex viruses
CA1259915A (en) * 1985-10-09 1989-09-26 Sailen S. Mookerjea Means to reduce plasma cholesterol
EP0222974B1 (de) * 1985-11-22 1991-11-13 Schweizerisches Serum- und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten Verfahren zur Herstellung eines Tollwutimpfstoffes und nach diesem Verfahren erhaltener Impfstoff
US4966709A (en) * 1985-12-19 1990-10-30 The Cleveland Clinic Foundation Thermofiltration of plasma
US5080796A (en) * 1985-12-19 1992-01-14 The Cleveland Clinic Foundation Thermofiltration of plasma
US5354262A (en) * 1986-02-18 1994-10-11 Boehringer Laboratories Apparatus for removal of insoluble fat from blood of a patient
US5203778A (en) * 1986-02-18 1993-04-20 Boehringer Laboratories Process and apparatus for removal of insoluble fat from blood of a patient
US4841023A (en) * 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
US5126240A (en) * 1986-09-29 1992-06-30 Curtiss Linda K Hybridomas and monoclonal paratopic molecules to apolipoprotein a-i
US4832034A (en) * 1987-04-09 1989-05-23 Pizziconi Vincent B Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids
US5128318A (en) * 1987-05-20 1992-07-07 The Rogosin Institute Reconstituted HDL particles and uses thereof
US5256767A (en) * 1987-06-10 1993-10-26 The Immune Response Corporation Retroviral antigens
JPH0829316B2 (ja) * 1987-10-16 1996-03-27 田辺製薬株式会社 パイロジェンの除去方法
DE3853219T2 (de) * 1987-11-20 1995-06-29 Kanegafuchi Chemical Ind Methode zur Entfernung von Serum-Amyloid-Protein.
US5112956A (en) * 1987-12-02 1992-05-12 The Nutrasweet Company Method for extraction of lipids and cholesterol
US4909940A (en) * 1987-12-30 1990-03-20 New York Blood Center, Inc. Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons
CA1335077C (en) * 1988-02-08 1995-04-04 Henri Isliker Process for the manufacture of apolipoproteins from human blood plasma or serum
US5948441A (en) * 1988-03-07 1999-09-07 The Liposome Company, Inc. Method for size separation of particles
JPH085804B2 (ja) * 1988-04-28 1996-01-24 財団法人化学及血清療法研究所 A型及びb型肝炎混合アジュバントワクチン
US5152743A (en) * 1988-08-05 1992-10-06 Healthdyne, Inc. Apparatus and method for selective separation of blood cholesterol
US5419759A (en) * 1988-11-17 1995-05-30 Naficy; Sadeque S. Apparatus and methods for treatment of HIV infections and AIDS
US5484396A (en) * 1988-11-17 1996-01-16 Naficy; Sadeque S. Method and device for treatment of HIV infections and AIDS
US5026479A (en) * 1990-02-13 1991-06-25 Union Carbide Industrial Gases Technology Corporation Fluid separation device
US5418130A (en) * 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
DE4018778A1 (de) * 1990-06-12 1991-12-19 Braun Melsungen Ag Adsorptionsmaterial zur selektiven entfernung von ldl- oder/und vldl
US5116307A (en) * 1990-07-09 1992-05-26 Collins Harvey T Method and system for treatment of AIDS
US5258149A (en) * 1990-11-27 1993-11-02 W. R. Grace & Co.-Conn. Process of making a membrane for high efficiency removal of low density lipoprotein-cholesterol from whole blood
US5187010A (en) * 1990-11-27 1993-02-16 W. R. Grace & Co.-Conn. Membrane having high affinity for low density lipoprotein-cholesterol from whole blood
US5236644A (en) * 1990-11-27 1993-08-17 W. R. Grace & Co.-Conn. Process of making membrane for removal of low density lipoprotein-cholesterol from whole blood
US5418061A (en) * 1990-11-27 1995-05-23 W. R. Grace & Co.-Conn. Microporous polysulfone supports suitable for removal of low density lipoprotein-cholesterol
US5879685A (en) * 1991-05-08 1999-03-09 Schweiz, Serum- & Impfinstitut Bern Immunostimulating and immunopotentiating reconstituted influenza virosomes and vaccines containing them
DE69229703T2 (de) * 1991-05-08 2000-04-27 Schweiz Serum & Impfinst Wiederhergestellte Influenza-Virosomen mit immunostimulierenden und immunoverstärkenden Eigenschaften und diese enthaltende Impfstoffe
GB9110808D0 (en) * 1991-05-17 1991-07-10 Retroscreen Ltd Aids vaccine and method for its production
US5211850A (en) * 1991-07-26 1993-05-18 Research Medical, Inc. Plasma filter sorbent system for removal of components from blood
JP2576744B2 (ja) * 1991-11-05 1997-01-29 日揮株式会社 液液接触塔
US5301694A (en) * 1991-11-12 1994-04-12 Philip Morris Incorporated Process for isolating plant extract fractions
US5919369A (en) * 1992-02-06 1999-07-06 Hemocleanse, Inc. Hemofiltration and plasmafiltration devices and methods
DE69329108T2 (de) * 1992-03-02 2001-03-22 Bioeng, Inc. Verfahren zur inaktivierung von viren
US5279540A (en) * 1992-09-24 1994-01-18 Davidson Michael H Method for reducing the risk of atherosclerosis
IL104015A0 (en) * 1992-12-07 1993-05-13 Doina International Ltd P Method for immunization of mammals against atherosclerosis and pharmaceutical compositions for obtaining said immunization
US5391143A (en) * 1993-03-12 1995-02-21 Kensey Nash Corporation Method and system for effecting weight reduction of living beings
CA2156721C (en) * 1993-03-16 1999-06-01 Thomas B. Okarma Removal of selected factors from whole blood or its components
US5401466A (en) * 1993-06-01 1995-03-28 Miles Inc. Device for the direct measurement of low density lipoprotein cholesterol
US5753227A (en) * 1993-07-23 1998-05-19 Strahilevitz; Meir Extracorporeal affinity adsorption methods for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases
USRE37584E1 (en) * 1993-07-30 2002-03-19 Aruba International Pty Ltd Solvent extraction methods for delipidating plasma
US7223410B1 (en) * 1994-08-05 2007-05-29 Sanofi Pasteur Limited Inactivated respiratory syncytial viral vaccines
ATA159993A (de) * 1993-08-10 1995-09-15 Dieter Dr Falkenhagen Anordnung zur elimination von substanzen aus flüssigkeiten
US5652339A (en) * 1993-12-31 1997-07-29 Rotkreuzstiftung Zentrallaboratorium Method of producing reconstituted lipoproteins
AU690707B2 (en) * 1994-06-22 1998-04-30 Fls Miljo A/S Mass transfer method and apparatus
US5962322A (en) * 1996-11-15 1999-10-05 Massachusetts Institute Of Technology Methods for modulation of cholesterol transport
US5637224A (en) * 1994-09-14 1997-06-10 New Jersey Institute Of Technology Hollow fiber contained liquid membrane pervaporation for removal of volatile organic compounds from aqueous solutions
DE4435612A1 (de) * 1994-10-05 1996-04-11 Braun Melsungen Ag Verfahren zur simultanen Entfernung von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus einer wäßrigen Flüssigkeit
JP3451142B2 (ja) * 1994-11-18 2003-09-29 本田技研工業株式会社 温度制御機構を備えたバッテリ組立体
US5634893A (en) * 1995-04-24 1997-06-03 Haemonetics Corporation Autotransfusion apparatus
US5719194A (en) * 1995-08-22 1998-02-17 Ausimont S.P.A. Prevention and treatment of topical viral infections with perfluoropolyethers or compositions thereof
US5911698A (en) * 1995-12-22 1999-06-15 Aruba International Pty. Ltd. Treatment for cardiovascular and related diseases
JP2001524839A (ja) * 1996-03-08 2001-12-04 ジョストラ ベントレイ インコーポレイテッド 選択的膜/吸着手法による自己血液の回収
US6171373B1 (en) * 1996-04-23 2001-01-09 Applied Ceramics, Inc. Adsorptive monolith including activated carbon, method for making said monolith, and method for adsorbing chemical agents from fluid streams
EP0915906B1 (de) * 1996-07-10 2000-09-06 American National Red Cross Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten
US5834015A (en) * 1996-09-11 1998-11-10 Albany Medical College Protein-lipid vesicles and autogenous vaccine comprising the same
US5707673A (en) * 1996-10-04 1998-01-13 Prewell Industries, L.L.C. Process for extracting lipids and organics from animal and plant matter or organics-containing waste streams
JP4075100B2 (ja) * 1996-10-16 2008-04-16 チッソ株式会社 アルキニル基を側鎖として有する液晶性化合物、液晶組成物および液晶表示素子
US6008221A (en) * 1996-11-06 1999-12-28 Bristol-Myers Squibb Company Method for treating Alzheimer's disease with folic acid
US6605588B1 (en) * 1996-11-27 2003-08-12 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
AT405939B (de) * 1997-02-24 1999-12-27 Immuno Ag Verfahren zur inaktivierung von lipidumhüllten viren
US6022333A (en) * 1997-05-01 2000-02-08 S.L.I.M. Tech, Ltd. Method and system for removing materials from lymphatic and other fluids
US6337368B1 (en) * 1997-06-03 2002-01-08 Kaneka Corporation Lipoprotein adsorbent and lipoprotein adsorber made with the use of the same
US5891432A (en) * 1997-07-29 1999-04-06 The Immune Response Corporation Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same
US6037323A (en) * 1997-09-29 2000-03-14 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6046166A (en) * 1997-09-29 2000-04-04 Jean-Louis Dasseux Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders
US6369048B1 (en) * 1998-01-12 2002-04-09 V.I. Technologies, Inc. Methods and compositions for inactivating viruses
US6080778A (en) * 1998-03-23 2000-06-27 Children's Medical Center Corporation Methods for decreasing beta amyloid protein
US6472421B1 (en) * 1998-11-13 2002-10-29 Nymox Corporation Methods for treating, preventing, and reducing the risk of the onset of alzheimer's disease using an HMG CoA reductase inhibitor
US20020055529A1 (en) * 1998-12-02 2002-05-09 Bisgaier Charles Larry Method for treating alzheimer's disease
US6214221B1 (en) * 1999-02-22 2001-04-10 Henry B. Kopf Method and apparatus for purification of biological substances
US6737066B1 (en) * 1999-05-06 2004-05-18 The Immune Response Corporation HIV immunogenic compositions and methods
AUPQ486699A0 (en) * 1999-12-23 2000-02-03 Aruba International Pty Ltd A method of treating infectious diseases
WO2001056579A1 (en) * 2000-02-04 2001-08-09 Esperion Therapeutics Inc. Methods for treating alzheimer's disease
US6835717B2 (en) * 2000-03-08 2004-12-28 The Johns Hopkins University School Of Medicine β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
US20090017069A1 (en) * 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
US7407663B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified immunodeficiency virus particles
US7407662B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content
AUPQ846900A0 (en) * 2000-06-29 2000-07-27 Aruba International Pty Ltd A vaccine
BR0114617A (pt) * 2000-10-11 2005-12-13 Esperion Therapeutics Inc Composto, composição farmacêutica, métodos para tratar ou previnir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticas
BR0206775A (pt) * 2001-01-26 2006-01-17 Immune Response Corp Inc Uso de um medicamento para tratar um indivìduo infectado com hiv, por combinação de imunização com interrupção estruturada do tratamento anti-retrovirótico
US6706008B2 (en) * 2001-03-06 2004-03-16 Baxter International Inc. Automated system and method for withdrawing compounds from blood
CA2451633C (en) * 2001-06-25 2010-11-30 Lipid Sciences, Inc. Systems and methods using a solvent for the removal of lipids from fluids
US6991727B2 (en) * 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US20060060520A1 (en) * 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
AU2002322284A1 (en) * 2001-06-25 2003-01-08 Lipid Sciences, Inc. Systems and methods using multiple solvents for the removal of lipids from fluids
AU2003268190B2 (en) * 2002-08-26 2008-04-03 Eli Lilly And Company Treating Alzheimers using delipidated protein particles
EP1917029B1 (de) * 2005-07-27 2013-01-23 Eli Lilly And Company Verfahren zur behandlung von krebszellen zur erzeugung einer modifizierten krebszelle, die eine immunogene antwort auslöst

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DE60118743T2 (de) 2006-10-26
PT1299130E (pt) 2006-07-31
WO2002000266A3 (en) 2002-03-28
DK1299130T3 (da) 2006-07-31
AUPQ846900A0 (en) 2000-07-27
WO2002000266A2 (en) 2002-01-03
ATE322914T1 (de) 2006-04-15
EP1299130A2 (de) 2003-04-09
JP5231379B2 (ja) 2013-07-10
JP2010077135A (ja) 2010-04-08
JP2004507462A (ja) 2004-03-11
AU2007201876B2 (en) 2009-09-24
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US20030133929A1 (en) 2003-07-17
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CA2412503A1 (en) 2002-01-03
US20030119782A1 (en) 2003-06-26
JP4852219B2 (ja) 2012-01-11
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EP1299130B1 (de) 2006-04-12
US20070212376A1 (en) 2007-09-13

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