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DE60118739D1 - Verfahren zur isolierung eines proteins - Google Patents

Verfahren zur isolierung eines proteins

Info

Publication number
DE60118739D1
DE60118739D1 DE60118739T DE60118739T DE60118739D1 DE 60118739 D1 DE60118739 D1 DE 60118739D1 DE 60118739 T DE60118739 T DE 60118739T DE 60118739 T DE60118739 T DE 60118739T DE 60118739 D1 DE60118739 D1 DE 60118739D1
Authority
DE
Germany
Prior art keywords
protein
interest
solid support
complex medium
insulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60118739T
Other languages
English (en)
Other versions
DE60118739T2 (de
Inventor
Patrick Berna
Christelle Clement
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meristem Therapeutics SA
Warner Lambert Co LLC
Original Assignee
Meristem Therapeutics SA
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meristem Therapeutics SA, Warner Lambert Co LLC filed Critical Meristem Therapeutics SA
Application granted granted Critical
Publication of DE60118739D1 publication Critical patent/DE60118739D1/de
Publication of DE60118739T2 publication Critical patent/DE60118739T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Surgery (AREA)
  • Nutrition Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60118739T 2000-06-23 2001-06-22 Verfahren zur isolierung eines proteins Expired - Fee Related DE60118739T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0008118A FR2810667B1 (fr) 2000-06-23 2000-06-23 Procede d'isolement et de purification d'une proteine, et proteine obtenue
FR0008118 2000-06-23
PCT/FR2001/001985 WO2001098473A2 (fr) 2000-06-23 2001-06-22 Procede d'isolement et de purification d'une proteine, et proteine obtenue

Publications (2)

Publication Number Publication Date
DE60118739D1 true DE60118739D1 (de) 2006-05-24
DE60118739T2 DE60118739T2 (de) 2006-11-09

Family

ID=8851639

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60118739T Expired - Fee Related DE60118739T2 (de) 2000-06-23 2001-06-22 Verfahren zur isolierung eines proteins

Country Status (8)

Country Link
US (1) US20040102615A1 (de)
EP (1) EP1297116B1 (de)
JP (1) JP2004505615A (de)
AT (1) ATE323154T1 (de)
AU (1) AU6924501A (de)
DE (1) DE60118739T2 (de)
FR (1) FR2810667B1 (de)
WO (1) WO2001098473A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1403274A1 (de) * 2002-09-30 2004-03-31 Meristem Therapeutics Verfahren zur Reinigung von rekombinanten Proteinen aus komplexen Medien sowie die auf diese Weise erhaltenen gereinigten Proteine
WO2005005460A1 (en) * 2003-07-10 2005-01-20 Novo Nordisk A/S Method of washing and concentrating protein precipitates by means of a centrifugal field and fluidization conditions
JP4149504B2 (ja) * 2006-12-07 2008-09-10 松下電器産業株式会社 フェリチンを基板上に二次元配列させる方法
WO2008143914A1 (en) * 2007-05-16 2008-11-27 The University Of Maryland, College Park Novel methods for recovery of leaf proteins
NZ602852A (en) 2010-04-30 2014-03-28 Asahi Kasei Pharma Corp Highly-purified soluble thrombomodulin and method for producing same
WO2014099577A1 (en) * 2012-12-17 2014-06-26 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
CN103013951B (zh) * 2012-12-27 2014-03-26 江南大学 一种提取纯化小麦胚芽脂肪酶的方法
GB201318840D0 (en) * 2013-10-24 2013-12-11 Univ Leeds Method and device for protein preparation
WO2017037219A1 (en) * 2015-09-04 2017-03-09 Basf Se Process for purification of crude polyether polyols
JP7037811B2 (ja) * 2018-03-19 2022-03-17 地方独立行政法人鳥取県産業技術センター スフェロイド形成促進剤の精製方法
CN112500471B (zh) * 2020-12-22 2022-09-27 中美华世通生物医药科技(武汉)股份有限公司 一种制备高澄清度蛋白琥珀酸铁的方法
CN112827210A (zh) * 2020-12-24 2021-05-25 四川德博尔制药有限公司 一种澄清胰脏提取液的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL182575C (nl) * 1974-06-10 Gb Fermentation Ind Inc Werkwijze voor de afscheiding van een lipolytisch enzym uit het fermentatiekweekmedium van mucor miehei, alsmede het gebruik van deze werkwijze voor de bereiding van lipase-vrije rennine.
DE3342870A1 (de) * 1983-11-26 1985-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Digitalis-antikoerper, verfahren zu ihrer herstellung und ihre verwendung zur therapie von digitalis-intoxikationen
US5169936A (en) * 1989-04-14 1992-12-08 Biogen, Inc. Protein purification on immobilized metal affinity resins effected by elution using a weak ligand
EP0574050A1 (de) * 1992-05-19 1993-12-15 Gist-Brocades N.V. Trennung und Reinigung von Fermentationsprodukt in grossen Massstab
FR2699179B1 (fr) * 1992-12-16 1995-01-06 Jouveinal Inst Rech Acides nucléiques codant pour la lipase gastrique de chien et dérivés polypeptidiques, leur utilisation pour la production de ces polypeptides, et compositions pharmaceutiques à base de ces derniers.
FR2733249B1 (fr) * 1995-04-20 1997-06-06 Biocem Lipase gastrique de chien recombinante et polypeptides derives produits par les plantes, leurs procedes d'obtention et leurs utilisations
EP0828753B1 (de) * 1995-06-02 2003-03-26 Novozymes A/S BEHANDLUNG EINER PROTEINLÖSUNG MIT A1/Fe UND ANSCHLIESENDE MEMBRANKONZENTRATION

Also Published As

Publication number Publication date
AU6924501A (en) 2002-01-02
EP1297116B1 (de) 2006-04-12
DE60118739T2 (de) 2006-11-09
US20040102615A1 (en) 2004-05-27
EP1297116A2 (de) 2003-04-02
WO2001098473A2 (fr) 2001-12-27
ATE323154T1 (de) 2006-04-15
FR2810667B1 (fr) 2004-09-03
FR2810667A1 (fr) 2001-12-28
JP2004505615A (ja) 2004-02-26
WO2001098473A3 (fr) 2002-05-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee