DE60118571D1 - Pharmazeutische zusammensetzungen zur behandlung von krebs welche thalidomid und topoisomerase inhibitoren enthalten - Google Patents
Pharmazeutische zusammensetzungen zur behandlung von krebs welche thalidomid und topoisomerase inhibitoren enthaltenInfo
- Publication number
- DE60118571D1 DE60118571D1 DE60118571T DE60118571T DE60118571D1 DE 60118571 D1 DE60118571 D1 DE 60118571D1 DE 60118571 T DE60118571 T DE 60118571T DE 60118571 T DE60118571 T DE 60118571T DE 60118571 D1 DE60118571 D1 DE 60118571D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- pharmaceutical compositions
- topoisomerase inhibitors
- cancer containing
- containing thalidomide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20414300P | 2000-05-15 | 2000-05-15 | |
US204143P | 2000-05-15 | ||
PCT/US2001/015327 WO2001087307A2 (en) | 2000-05-15 | 2001-05-10 | Compositions and methods for the treatment of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60118571D1 true DE60118571D1 (de) | 2006-05-18 |
DE60118571T2 DE60118571T2 (de) | 2007-02-01 |
Family
ID=22756804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60118571T Expired - Lifetime DE60118571T2 (de) | 2000-05-15 | 2001-05-10 | Pharmazeutische zusammensetzungen zur behandlung von krebs welche thalidomid und topoisomerase inhibitoren enthalten |
Country Status (19)
Country | Link |
---|---|
US (2) | US7435726B2 (de) |
EP (1) | EP1307197B1 (de) |
JP (1) | JP5409981B2 (de) |
KR (1) | KR100790589B1 (de) |
AR (1) | AR029084A1 (de) |
AT (1) | ATE322266T1 (de) |
AU (2) | AU6147401A (de) |
BR (1) | BR0110877A (de) |
CA (1) | CA2408707C (de) |
DE (1) | DE60118571T2 (de) |
DK (1) | DK1307197T3 (de) |
ES (1) | ES2258084T3 (de) |
HK (1) | HK1054502A1 (de) |
MX (1) | MXPA02011218A (de) |
NZ (1) | NZ522767A (de) |
PT (1) | PT1307197E (de) |
TW (1) | TWI289449B (de) |
WO (1) | WO2001087307A2 (de) |
ZA (1) | ZA200209638B (de) |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050192360A1 (en) * | 1999-04-14 | 2005-09-01 | Li Chiang J. | Method of treatment of pancreatic cancer |
US7812169B2 (en) * | 2000-11-30 | 2010-10-12 | The Children's Medical Center Corporation | Method of synthesis of 4-amino-thalidomide enantiomers |
US20020128228A1 (en) * | 2000-12-01 | 2002-09-12 | Wen-Jen Hwu | Compositions and methods for the treatment of cancer |
US6440738B1 (en) * | 2001-02-08 | 2002-08-27 | Isis Pharmaceuticals, Inc. | Antisense modulation of casein kinase 2-beta expression |
AU2002249103A1 (en) * | 2001-03-29 | 2002-10-15 | Topo Target Aps | Succinimide and maleimide derivatives and their use as topoisomerase ii catalytic inhibitors |
SK1472004A3 (en) * | 2001-09-24 | 2004-10-05 | Tosk Inc | Reduced toxicity cisplatin formulations and methods for using the same |
CA2383259A1 (en) * | 2002-04-23 | 2003-10-23 | Celator Technologies Inc. | Synergistic compositions |
US20080075762A1 (en) * | 2001-10-03 | 2008-03-27 | Paul Tardi | Compositions for delivery of drug combinations |
US7850990B2 (en) * | 2001-10-03 | 2010-12-14 | Celator Pharmaceuticals, Inc. | Compositions for delivery of drug combinations |
US20080249183A1 (en) * | 2001-11-29 | 2008-10-09 | Steiner Mitchell S | Treatment of androgen-deprivation induced osteoporosis |
US20070197664A1 (en) * | 2001-11-29 | 2007-08-23 | Steiner Mitchell S | Prevention and treatment of androgen-deprivation induced osteoporosis |
RU2316326C2 (ru) * | 2001-12-03 | 2008-02-10 | Байер Фамэсьютиклс Копэрейшн | Способ и композиция для лечения ракового заболевания, тозилат и фармацевтически приемлемые соли n-(4-хлор-3-(трифторметил)фенил)-n'-(4-(2-(n-метилкарбамоил)-4-пиридилокси)фенил)мочевины |
EP1454626A4 (de) * | 2001-12-14 | 2006-07-19 | Sundory Co Ltd | Verfahren zur induktion von apoptosis und zusammensetzungen dafür |
EA008302B1 (ru) * | 2002-03-26 | 2007-04-27 | Баниу Фармасьютикал Ко., Лтд. | Комбинированное применение противоопухолевого производного индолопирролокарбазола и другого противоопухолевого агента |
CN1705439A (zh) * | 2002-04-12 | 2005-12-07 | 细胞基因公司 | 干细胞和祖细胞分化的调节、鉴定及其应用 |
US7498171B2 (en) | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
AU2003221767B2 (en) * | 2002-04-24 | 2008-07-31 | Research Development Foundation | Synergistic effects of nuclear transcription factor NF-kB inhibitors and anti-neoplastic agents |
USRE48890E1 (en) | 2002-05-17 | 2022-01-11 | Celgene Corporation | Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation |
US7393862B2 (en) | 2002-05-17 | 2008-07-01 | Celgene Corporation | Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias |
EP2258363A1 (de) * | 2002-05-17 | 2010-12-08 | Celgene Corporation | Zusammensetzungen zur Behandlung von Krebs |
US20100129363A1 (en) * | 2002-05-17 | 2010-05-27 | Zeldis Jerome B | Methods and compositions using pde4 inhibitors for the treatment and management of cancers |
WO2003097052A2 (en) * | 2002-05-17 | 2003-11-27 | Celgene Corporation | Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases |
US7968569B2 (en) | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
US7323479B2 (en) * | 2002-05-17 | 2008-01-29 | Celgene Corporation | Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline |
WO2004000229A2 (en) * | 2002-06-24 | 2003-12-31 | Research Development Foundation | Treatment of human multiple myeloma by curcumin |
US20040034099A1 (en) * | 2002-06-27 | 2004-02-19 | Ramsey Beverly J. | Pharmaceutical composition |
EP1551385A4 (de) * | 2002-10-15 | 2008-10-22 | Celgene Corp | Selektive cytokin-hemmenden arzneimittel zur behandlung von myelodysplastischem syndrom |
US7189740B2 (en) * | 2002-10-15 | 2007-03-13 | Celgene Corporation | Methods of using 3-(4-amino-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myelodysplastic syndromes |
US8404716B2 (en) | 2002-10-15 | 2013-03-26 | Celgene Corporation | Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine |
US8404717B2 (en) * | 2002-10-15 | 2013-03-26 | Celgene Corporation | Methods of treating myelodysplastic syndromes using lenalidomide |
US11116782B2 (en) | 2002-10-15 | 2021-09-14 | Celgene Corporation | Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine |
US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
CA2505003A1 (en) * | 2002-11-06 | 2004-05-27 | Celgene Corporation | Methods of using and compositions comprising selective cytokine inhibitory drugs for the treatment and management of myeloproliferative diseases |
US7354948B2 (en) * | 2002-11-06 | 2008-04-08 | Celgene Corporation | Methods for treatment of chronic uveitis using cyclopropyl-n-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindoline-4-yl}carboxamide |
WO2004087713A1 (en) * | 2003-03-31 | 2004-10-14 | Pfizer Inc. | Salts of tricyclic inhibitors of poly(adp-ribose) polymerases |
CL2004001004A1 (es) * | 2003-05-19 | 2005-03-18 | Upjohn Co | Combinacion farmaceutica que comprende irinotecan y revimid para tratar el mieloma multiple. |
WO2004113502A2 (en) * | 2003-06-20 | 2004-12-29 | Avalon Pharmaceuticals, Inc. | Identification of therapeutic agents using genetic fingerprinting |
US7264819B2 (en) * | 2003-06-23 | 2007-09-04 | Anticancer, Inc. | Lyase treatment for P. carinii |
US20050049299A1 (en) * | 2003-08-26 | 2005-03-03 | Aggarwal Bharat B. | Selective inhibitors of stat-3 activation and uses thereof |
CA2536380A1 (en) | 2003-08-26 | 2005-02-26 | Research Development Foundation | Osteoclastogenesis inhibitors and uses thereof |
UA83504C2 (en) | 2003-09-04 | 2008-07-25 | Селджин Корпорейшн | Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione |
US20050100529A1 (en) * | 2003-11-06 | 2005-05-12 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders |
BRPI0416275A (pt) * | 2003-11-06 | 2007-01-23 | Celgene Corp | métodos de tratar, controlar ou prevenir um cáncer especìfico e uma doença associada com angiogênese indesejada |
CN101966183A (zh) * | 2003-12-02 | 2011-02-09 | 细胞基因公司 | 用于治疗和控制血红蛋白病和贫血病的方法和组合物 |
ES2325506T3 (es) * | 2003-12-12 | 2009-09-07 | Quiral Quimica Do Brasil | Procedimiento para la preparacion de principios activos farmaceuticos (api) anhidros e hidratados; composiciones farmaceuticas estables preparadas a partir de los mismos y usos de dichas composiciones. |
JP2007523189A (ja) * | 2004-02-20 | 2007-08-16 | アークル・インコーポレーテツド | 結腸癌の治療のためのβ−ラパコンの使用 |
JP2007523190A (ja) * | 2004-02-20 | 2007-08-16 | アークル・インコーポレーテツド | 肺癌の治療のためのβ−ラパコンの使用 |
EP1722777A2 (de) * | 2004-02-20 | 2006-11-22 | Arqule, Inc. | Verwendung von beta-lapachone zur behandlung von pangreaskarzinomen |
EP1737493B1 (de) | 2004-02-25 | 2011-06-29 | Dana-Farber Cancer Institute, Inc. | Hemmer des insulinartigen wachstumsfaktor-rezeptors-1 zur hemmung von tumorzellwachstum |
WO2005094322A2 (en) | 2004-03-29 | 2005-10-13 | University Of South Florida | Effective treatment of tumors and cancer with triciribine and related compounds |
US20100009928A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and taxanes and methods of use thereof |
US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
US20110008327A1 (en) * | 2004-03-29 | 2011-01-13 | Cheng Jin Q | Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof |
US20100173864A1 (en) | 2004-03-29 | 2010-07-08 | Cheng Jin Q | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
US20100028339A1 (en) | 2004-03-29 | 2010-02-04 | Cheng Jin Q | Compositions including triciribine and trastuzumab and methods of use thereof |
CA2562715A1 (en) * | 2004-04-14 | 2005-11-24 | Celgene Corporation | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myelodysplastic syndromes |
US20080213213A1 (en) * | 2004-04-14 | 2008-09-04 | Zeldis Jerome B | Method For the Treatment of Myelodysplastic Syndromes Using (+)-2-[1-(3-Ethoxy-4-Methoxyphenyl)-2-Methylsulfonylethyl]-4-Acetylaminoisoindoline-1,3-Dione |
WO2005113018A2 (en) * | 2004-04-27 | 2005-12-01 | Wellstat Biologics Corporation | Cancer treatment using viruses and camptothecins |
EP1750697A4 (de) * | 2004-05-05 | 2009-08-26 | Celgene Corp | Verfahren und zusammensetzungen mit selektiven cytokin-hemmenden arzneimitteln zur behandlung und versorgung von krebs und anderen erkrankungen |
WO2005112917A1 (en) * | 2004-05-05 | 2005-12-01 | Celgene Corporation | Methods of using and compositions comprising selective cytokine inhibitory drugs for the treatment and management of myeloproliferative diseases |
US20060270707A1 (en) * | 2005-05-24 | 2006-11-30 | Zeldis Jerome B | Methods and compositions using 4-[(cyclopropanecarbonylamino)methyl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione for the treatment or prevention of cutaneous lupus |
ATE502954T1 (de) * | 2005-06-14 | 2011-04-15 | Protox Therapeutics Inc | Verfahren zur behandlung oder prävention gutartiger prostatahyperplasie unter verwendung modifizierter porenbildender proteine |
US20080138295A1 (en) * | 2005-09-12 | 2008-06-12 | Celgene Coporation | Bechet's disease using cyclopropyl-N-carboxamide |
US20070066512A1 (en) * | 2005-09-12 | 2007-03-22 | Dominique Verhelle | Methods and compositions using immunomodulatory compounds for the treatment of disorders associated with low plasma leptin levels |
CN1870631B (zh) * | 2005-11-11 | 2010-04-14 | 华为技术有限公司 | 媒体网关的门控方法 |
US20070155791A1 (en) * | 2005-12-29 | 2007-07-05 | Zeldis Jerome B | Methods for treating cutaneous lupus using aminoisoindoline compounds |
CA2640598A1 (en) * | 2006-02-03 | 2007-08-09 | Noboru Yamazaki | Liposome preparation |
JP2010500050A (ja) * | 2006-04-27 | 2010-01-07 | シェノイ,ナルマダ,アール. | 身体通路の疾病を治療又は予防する組成物及び方法 |
CL2007002218A1 (es) | 2006-08-03 | 2008-03-14 | Celgene Corp Soc Organizada Ba | Uso de 3-(4-amino-1-oxo-1,3-dihidro-isoindol-2-il)-piperidina 2,6-diona para la preparacion de un medicamento util para el tratamiento de linfoma de celula de capa. |
US20080051380A1 (en) | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods and compositions for treating cancer |
EP2014651A1 (de) * | 2007-07-12 | 2009-01-14 | Exonhit Therapeutics SA | Verbindungen und Verfahren zur Modulierung von Rho-GTPasen |
US7893045B2 (en) | 2007-08-07 | 2011-02-22 | Celgene Corporation | Methods for treating lymphomas in certain patient populations and screening patients for said therapy |
CA2742252A1 (en) * | 2007-11-01 | 2009-05-07 | Celgene Corporation | Cytidine analogs for treatment of myelodysplastic syndromes |
AU2008326251B2 (en) * | 2007-11-21 | 2014-03-06 | Mateon Therapeutics, Inc. | Method for treating hematopoietic neoplasms |
US20090137631A1 (en) * | 2007-11-22 | 2009-05-28 | National Yang-Ming University | Methods and pharmaceutical compositions for regulation of g- and/or gc-rich nucleic acid expression |
CA2751892A1 (en) | 2009-01-15 | 2010-07-22 | Rutgers, The State University Of New Jersey | Benzo [c] phenanthridines as antimicrobial agents |
CA2760526A1 (en) | 2009-04-30 | 2010-11-04 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
US8933096B2 (en) | 2010-06-09 | 2015-01-13 | Rugers, The State University of New Jersey | Antimicrobial agents |
WO2011163610A2 (en) | 2010-06-25 | 2011-12-29 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
WO2012092485A1 (en) | 2010-12-31 | 2012-07-05 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory rna molecules |
KR101369936B1 (ko) * | 2011-12-28 | 2014-03-06 | 연세대학교 산학협력단 | 탈리도마이드를 포함하는 루프스 신염 치료용 약학 조성물 |
WO2013106756A2 (en) | 2012-01-13 | 2013-07-18 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
EP2828245A1 (de) | 2012-03-21 | 2015-01-28 | Rutgers, The State University of New Jersey | Antimikrobiotika |
WO2014180882A2 (en) * | 2013-05-07 | 2014-11-13 | Universitat De Barcelona | Treatment of brain metastasis from cancer |
US20170080093A1 (en) * | 2013-10-22 | 2017-03-23 | Tyme, Inc. | Tyrosine Derivatives And Compositions Comprising Them |
US9458150B2 (en) | 2013-11-08 | 2016-10-04 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
BR112017003620A2 (pt) | 2014-08-22 | 2017-12-05 | Celgene Corp | métodos de tratamento de mieloma múltiplo com compostos imunomoduladores em combinação com anticorpos |
JP2018527302A (ja) | 2015-06-26 | 2018-09-20 | セルジーン コーポレイション | 免疫調節化合物を用いたカポジ肉腫またはkshv誘発性リンパ腫の治療方法、及びバイオマーカーの使用 |
EP3337495A4 (de) | 2015-08-18 | 2019-04-10 | Mateon Therapeutics, Inc. | Verwendung von vdas zur verbesserung von immunmodulierenden therapien gegen tumoren |
JP2019507801A (ja) | 2016-02-25 | 2019-03-22 | タクシス ファーマシューティカルズ, インコーポレイテッド | 合成プロセス及び中間体 |
WO2017188791A1 (ko) * | 2016-04-29 | 2017-11-02 | (주)나디안바이오 | 나프토퀴논계 화합물을 유효성분으로 포함하는 항암제 치료 관련 부작용으로 나타나는 피로, 악액질, 통증, 인지능력 저하 및 조혈줄기세포 감소의 예방 또는 개선용 조성물 |
CN119606966A (zh) | 2016-07-29 | 2025-03-14 | 詹森药业有限公司 | 治疗前列腺癌的方法 |
KR101851470B1 (ko) | 2016-12-19 | 2018-06-11 | 한림대학교 산학협력단 | 퀘세틴이 함유된 유방암 예방 및 치료를 위한 약제학적 조성물 |
CN110891566B (zh) | 2017-03-30 | 2023-12-19 | 塔克西斯医药股份有限公司 | 合成方法和合成中间体 |
US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
US5422344A (en) * | 1990-05-08 | 1995-06-06 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Method of treating retroviral infections in mammals |
AU1531492A (en) | 1991-02-14 | 1992-09-15 | Rockefeller University, The | Method for controlling abnormal concentration tnf alpha in human tissues |
US5629327A (en) | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
US5643915A (en) | 1995-06-06 | 1997-07-01 | Andrulis Pharmaceuticals Corp. | Treatment of ischemia/reperfusion injury with thalidomide alone or in combination with other therapies |
US5654312A (en) | 1995-06-07 | 1997-08-05 | Andrulis Pharmaceuticals | Treatment of inflammatory and/or autoimmune dermatoses with thalidomide alone or in combination with other agents |
GB9523493D0 (en) * | 1995-11-16 | 1996-01-17 | British Biotech Pharm | Preparation of allyl succinate derivatives and starting materials therefore |
-
2001
- 2001-05-10 EP EP01935373A patent/EP1307197B1/de not_active Expired - Lifetime
- 2001-05-10 DK DK01935373T patent/DK1307197T3/da active
- 2001-05-10 WO PCT/US2001/015327 patent/WO2001087307A2/en active IP Right Grant
- 2001-05-10 NZ NZ522767A patent/NZ522767A/en not_active IP Right Cessation
- 2001-05-10 JP JP2001583775A patent/JP5409981B2/ja not_active Expired - Fee Related
- 2001-05-10 PT PT01935373T patent/PT1307197E/pt unknown
- 2001-05-10 BR BR0110877-8A patent/BR0110877A/pt active Search and Examination
- 2001-05-10 AU AU6147401A patent/AU6147401A/xx active Pending
- 2001-05-10 DE DE60118571T patent/DE60118571T2/de not_active Expired - Lifetime
- 2001-05-10 CA CA2408707A patent/CA2408707C/en not_active Expired - Fee Related
- 2001-05-10 AU AU2001261474A patent/AU2001261474B2/en not_active Ceased
- 2001-05-10 MX MXPA02011218A patent/MXPA02011218A/es active IP Right Grant
- 2001-05-10 AT AT01935373T patent/ATE322266T1/de active
- 2001-05-10 KR KR1020027015443A patent/KR100790589B1/ko not_active Expired - Fee Related
- 2001-05-10 ES ES01935373T patent/ES2258084T3/es not_active Expired - Lifetime
- 2001-05-14 US US09/853,617 patent/US7435726B2/en not_active Expired - Fee Related
- 2001-05-15 AR ARP010102298A patent/AR029084A1/es unknown
- 2001-06-26 TW TW090111620A patent/TWI289449B/zh active
-
2002
- 2002-11-27 ZA ZA200209638A patent/ZA200209638B/en unknown
-
2003
- 2003-08-29 HK HK03106199A patent/HK1054502A1/xx not_active IP Right Cessation
-
2005
- 2005-03-09 US US11/074,849 patent/US20050148524A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1307197B1 (de) | 2006-04-05 |
DE60118571T2 (de) | 2007-02-01 |
KR20030025922A (ko) | 2003-03-29 |
AU2001261474B2 (en) | 2006-03-09 |
NZ522767A (en) | 2004-07-30 |
ZA200209638B (en) | 2003-11-27 |
CA2408707C (en) | 2010-04-13 |
MXPA02011218A (es) | 2004-08-19 |
BR0110877A (pt) | 2003-03-11 |
US20050148524A1 (en) | 2005-07-07 |
JP5409981B2 (ja) | 2014-02-05 |
KR100790589B1 (ko) | 2008-01-02 |
DK1307197T3 (da) | 2006-07-03 |
EP1307197A2 (de) | 2003-05-07 |
AR029084A1 (es) | 2003-06-04 |
WO2001087307A3 (en) | 2002-07-25 |
CA2408707A1 (en) | 2001-11-22 |
ES2258084T3 (es) | 2006-08-16 |
ATE322266T1 (de) | 2006-04-15 |
HK1054502A1 (en) | 2003-12-05 |
AU6147401A (en) | 2001-11-26 |
JP2003533484A (ja) | 2003-11-11 |
TWI289449B (en) | 2007-11-11 |
US7435726B2 (en) | 2008-10-14 |
US20020035090A1 (en) | 2002-03-21 |
WO2001087307A2 (en) | 2001-11-22 |
PT1307197E (pt) | 2006-08-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60118571D1 (de) | Pharmazeutische zusammensetzungen zur behandlung von krebs welche thalidomid und topoisomerase inhibitoren enthalten | |
ATE503461T1 (de) | Pharmazeutische zusammensetzungen zur behandlung von asthma | |
DE50206657D1 (de) | Pharmazeutische zusammensetzung zur behandlung von multiple sklerose | |
DE60031127D1 (de) | Nsaid und egfr kinase inhibitoren enthaltende pharmazeutische formulierung zur behandlung oder inhibierung von dickdarmpolypen und kolorektalem krebs | |
DE60035378D1 (de) | Gerät zur Behandlung von Bandscheiben | |
ATE291438T1 (de) | Pharmazeutische zusammensetzung zur behandlung von akutem schmerz, chronischem schmerz und/oder neuropathischem schmerz und migräne | |
ATE447947T1 (de) | Pharmazeutische zubereitungen zur behandlung von insulinresitenz | |
DE60105295D1 (de) | Chinazolinderivate zur behandlung von tumoren | |
DE60108080D1 (de) | Aminopyrazolderivate zur behandlung von übergewicht und anderen gesundheitsstörungen | |
DE602004022036D1 (de) | Verfahren zur behandlung von atherosklerose, dyslipidämie und verwandten erkrankungen und pharmazeutische zusammensetzungen | |
EE200100717A (et) | Indasooliühendid ja farmatseutilised kompositsioonid proteiini kinaaside inhibeerimiseks ja meetodid nende kasutamiseks | |
NO20024610D0 (no) | Synergistiske metoder og blandinger for behandling av kreft | |
DE60227095D1 (de) | Zusammensetzungen und verfahren zur behandlung von abgebundenem gips | |
DE60124302D1 (de) | Thiazolderivate zur behandlung von ppar-lierte krankheiten | |
DE60023128D1 (de) | Pyrazolecarboxamide zur behandlung von fettleibigkeit und anderen erkrankungen | |
IL171961A (en) | Dictopyrazine compounds and pharmaceutical preparations containing them for the treatment of T-mediated diseases | |
ATE265857T1 (de) | Pharmazeutische oder diätetische zusammensetzung zur prävention oder behandlung von hyperoxalurie | |
DE69802260D1 (de) | Pharmazeutische Zusammensetzungen enthaltend Lactobacillus brevis und Lactobacillus salivarius zur Behandlung von Vaginainfektionen | |
ATE293971T1 (de) | Pharmazeutische kombinationen enthaltend tegaserod und omeprazole und ihre verwendung zur behandlung gastrointestinaler krankheiten | |
DE69942680D1 (de) | Verfahren und Zusammensetzungen zur Prävention und Behandlung von Anämie | |
EP1255765A4 (de) | Pharmazeutische zusammensetzung und therapeutische behandlung von rheumatischer arthritis | |
DE60229959D1 (de) | Kombinationstherapie zur behandlung von krebs | |
DE60136477D1 (de) | Retinoide zur behandlung von emphysem | |
EP1117395A4 (de) | Verbindungen zur behandlung von östrogenabhängigen erkrankungen und deren herstellungs und verwendungsmethoden | |
DE60218375D1 (de) | Pharmazeutische Zusammensetzung zur Behandlung gynäkologischer Erkrankungen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8380 | Miscellaneous part iii |
Free format text: DIE ORTSANGABE BEIM ANMELDER WURDER GEAENDERT IN SUMMIT. |