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DE60103865D1 - Arzneizubereitungen und deren herstellungsverfahren - Google Patents

Arzneizubereitungen und deren herstellungsverfahren

Info

Publication number
DE60103865D1
DE60103865D1 DE60103865T DE60103865T DE60103865D1 DE 60103865 D1 DE60103865 D1 DE 60103865D1 DE 60103865 T DE60103865 T DE 60103865T DE 60103865 T DE60103865 T DE 60103865T DE 60103865 D1 DE60103865 D1 DE 60103865D1
Authority
DE
Germany
Prior art keywords
particles
production method
emulsion
active substance
drug preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60103865T
Other languages
English (en)
Other versions
DE60103865T2 (de
Inventor
John Nicholas Staniforth
Michael John Tobyn
Cheryl Julia Clinch
Robert Price
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vectura Ltd
Original Assignee
Vectura Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9889294&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60103865(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vectura Ltd filed Critical Vectura Ltd
Publication of DE60103865D1 publication Critical patent/DE60103865D1/de
Application granted granted Critical
Publication of DE60103865T2 publication Critical patent/DE60103865T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Colloid Chemistry (AREA)
DE60103865T 2000-04-05 2001-04-05 Arzneizubereitungen und deren herstellungsverfahren Expired - Lifetime DE60103865T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0008411.1A GB0008411D0 (en) 2000-04-05 2000-04-05 Pharmaceutical preparations and their manufacture
GB0008411 2000-04-05
PCT/GB2001/001562 WO2001074332A1 (en) 2000-04-05 2001-04-05 Pharmaceutical preparations and their manufacture

Publications (2)

Publication Number Publication Date
DE60103865D1 true DE60103865D1 (de) 2004-07-22
DE60103865T2 DE60103865T2 (de) 2004-10-28

Family

ID=9889294

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60103865T Expired - Lifetime DE60103865T2 (de) 2000-04-05 2001-04-05 Arzneizubereitungen und deren herstellungsverfahren

Country Status (22)

Country Link
US (2) US20030157182A1 (de)
EP (1) EP1267833B1 (de)
JP (1) JP2003528907A (de)
KR (1) KR20030011816A (de)
CN (1) CN1420764A (de)
AT (1) ATE269057T1 (de)
AU (1) AU4440601A (de)
BR (1) BR0109802A (de)
CA (1) CA2404367A1 (de)
DE (1) DE60103865T2 (de)
DK (1) DK1267833T3 (de)
ES (1) ES2218402T3 (de)
GB (1) GB0008411D0 (de)
HU (1) HUP0300334A3 (de)
IL (1) IL152074A0 (de)
MX (1) MXPA02009797A (de)
NO (1) NO20024737L (de)
PL (1) PL357808A1 (de)
PT (1) PT1267833E (de)
TR (1) TR200401567T4 (de)
WO (1) WO2001074332A1 (de)
ZA (1) ZA200207508B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2520841T3 (es) * 2003-02-21 2014-11-11 University Of Bath Procedimiento para la producción de partículas
GB0425758D0 (en) * 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
GB0426301D0 (en) * 2004-11-30 2004-12-29 Vectura Ltd Pharmaceutical formulations
EP1909762A2 (de) * 2005-07-28 2008-04-16 Isp Investments Inc. Amorphes efavirenz und seine herstellung
JP2007326083A (ja) * 2006-06-09 2007-12-20 Fujifilm Corp 固体微粒子及びその製造方法
US20080085315A1 (en) * 2006-10-10 2008-04-10 John Alfred Doney Amorphous ezetimibe and the production thereof
CN101541415B (zh) * 2006-11-14 2012-08-22 巴斯夫欧洲公司 生产亚微核/壳粒子的微悬浮乳液或悬浮液的方法
US20080152717A1 (en) * 2006-12-14 2008-06-26 Isp Investments, Inc. Amorphous valsartan and the production thereof
WO2008080037A2 (en) * 2006-12-21 2008-07-03 Isp Investments Inc. Carotenoids of enhanced bioavailability
EP2125938A2 (de) * 2007-01-26 2009-12-02 Isp Investments Inc. Verfahren zur herstellung einer formulierung für sprühgetrocknete produkte
WO2008092046A2 (en) * 2007-01-26 2008-07-31 Isp Investments Inc. Amorphous oxcarbazepine and the production thereof
PL220269B1 (pl) 2008-04-21 2015-09-30 Przedsiębiorstwo Produkcji Farmaceutycznej Hasco Lek Spółka Akcyjna Kompozytowy nośnik leków proszkowych, sposób wytwarzania nośnika leków oraz urządzenie do wytwarzania cząstek nośnika kompozytowego
WO2010007447A1 (en) 2008-07-18 2010-01-21 Prosonix Limited Process for improving crystallinity
CN102107127B (zh) * 2011-01-11 2015-04-22 西安蓝晓科技新材料股份有限公司 一种粉体造粒技术
JP2014520865A (ja) * 2011-07-15 2014-08-25 ユーファーマ プロプライエタリー リミテッド 制酸剤、麻酔薬、ならびに二酸化ケイ素と二酸化チタンとを含んでなる無機マトリックスを含んでなる経口用組成物
PT107433B (pt) * 2014-01-28 2018-12-04 Hovione Farm S A Processo de redução e controlo do tamanho de partícula
CN109890225B (zh) * 2016-11-10 2022-05-27 日本烟草产业株式会社 球状的粉末凝聚体及其制造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2608988B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
SE464743B (sv) * 1989-06-21 1991-06-10 Ytkemiska Inst Foerfarande foer framstaellning av laekemedelspartiklar
FR2694895B1 (fr) * 1992-08-20 1994-11-10 Coletica Procédé de fabrication de microparticules en émulsion par modification de la composition chimique de la phase dispersée après émulsification.
CA2176716C (en) * 1993-11-19 2009-04-07 Ramstack, J. Michael Preparation of biodegradable microparticles containing a biologically active agent
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
DE19617085A1 (de) * 1996-04-29 1997-10-30 Bayer Ag Verfahren zur Herstellung von feinstteiligen Kristallisationsprodukten
US5792477A (en) * 1996-05-07 1998-08-11 Alkermes Controlled Therapeutics, Inc. Ii Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent
GB9700624D0 (en) * 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
US6150505A (en) 1997-09-19 2000-11-21 Hadasit Medical Research Services & Development Ltd. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
US6565885B1 (en) * 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions

Also Published As

Publication number Publication date
PL357808A1 (en) 2004-07-26
NO20024737L (no) 2002-11-18
KR20030011816A (ko) 2003-02-11
MXPA02009797A (es) 2004-09-13
ATE269057T1 (de) 2004-07-15
EP1267833B1 (de) 2004-06-16
CA2404367A1 (en) 2001-10-11
AU4440601A (en) 2001-10-15
CN1420764A (zh) 2003-05-28
HUP0300334A2 (hu) 2003-09-29
PT1267833E (pt) 2004-11-30
GB0008411D0 (en) 2000-05-24
JP2003528907A (ja) 2003-09-30
TR200401567T4 (tr) 2004-08-23
ES2218402T3 (es) 2004-11-16
DK1267833T3 (da) 2004-07-19
ZA200207508B (en) 2003-09-19
IL152074A0 (en) 2003-05-29
BR0109802A (pt) 2003-01-21
HUP0300334A3 (en) 2005-04-28
US20100015234A1 (en) 2010-01-21
DE60103865T2 (de) 2004-10-28
NO20024737D0 (no) 2002-10-02
US20030157182A1 (en) 2003-08-21
WO2001074332A1 (en) 2001-10-11
EP1267833A1 (de) 2003-01-02

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Legal Events

Date Code Title Description
8363 Opposition against the patent