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DE60045878D1 - Pharmaceutically active isoindoline derivatives - Google Patents

Pharmaceutically active isoindoline derivatives

Info

Publication number
DE60045878D1
DE60045878D1 DE60045878T DE60045878T DE60045878D1 DE 60045878 D1 DE60045878 D1 DE 60045878D1 DE 60045878 T DE60045878 T DE 60045878T DE 60045878 T DE60045878 T DE 60045878T DE 60045878 D1 DE60045878 D1 DE 60045878D1
Authority
DE
Germany
Prior art keywords
pharmaceutically active
isoindoline derivatives
active isoindoline
derivatives
pharmaceutically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60045878T
Other languages
German (de)
Inventor
Hon-Wah Man
George Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celgene Corp
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/708,199 external-priority patent/US6667316B1/en
Application filed by Celgene Corp filed Critical Celgene Corp
Application granted granted Critical
Publication of DE60045878D1 publication Critical patent/DE60045878D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60045878T 1999-11-12 2000-11-09 Pharmaceutically active isoindoline derivatives Expired - Lifetime DE60045878D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16516899P 1999-11-12 1999-11-12
US59034400A 2000-06-08 2000-06-08
US09/708,199 US6667316B1 (en) 1999-11-12 2000-11-08 Pharmaceutically active isoindoline derivatives

Publications (1)

Publication Number Publication Date
DE60045878D1 true DE60045878D1 (en) 2011-06-01

Family

ID=29738942

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60045878T Expired - Lifetime DE60045878D1 (en) 1999-11-12 2000-11-09 Pharmaceutically active isoindoline derivatives

Country Status (3)

Country Link
CN (1) CN101074210A (en)
DE (1) DE60045878D1 (en)
TW (2) TWI276628B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105294533A (en) * 2015-12-02 2016-02-03 宋彤云 Pharmaceutical composition for treating bone diseases
CN107698484B (en) * 2017-11-13 2020-05-19 广东中科药物研究有限公司 Preparation method and application of lenalidomide derivative
CN111170925B (en) * 2020-01-09 2023-01-17 常州大学 Phthalimide compound as PDE2/4 dual inhibitor and preparation method thereof
CN114436935B (en) * 2022-02-14 2024-05-28 河南师范大学 Method for synthesizing optically active beta-amino ketone derivative by asymmetric conjugate addition

Also Published As

Publication number Publication date
CN101074210A (en) 2007-11-21
TW200502219A (en) 2005-01-16
TWI276628B (en) 2007-03-21
TWI261592B (en) 2006-09-11

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