DE60040089D1 - Menschliches homolog aus der familie der metalloproteasen - Google Patents
Menschliches homolog aus der familie der metalloproteasenInfo
- Publication number
- DE60040089D1 DE60040089D1 DE60040089T DE60040089T DE60040089D1 DE 60040089 D1 DE60040089 D1 DE 60040089D1 DE 60040089 T DE60040089 T DE 60040089T DE 60040089 T DE60040089 T DE 60040089T DE 60040089 D1 DE60040089 D1 DE 60040089D1
- Authority
- DE
- Germany
- Prior art keywords
- family
- human homolog
- polypeptides
- metal proteases
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- C—CHEMISTRY; METALLURGY
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
- C12N9/6497—Endothelin-converting enzyme (3.4.24.71)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24071—Endothelin-converting enzyme 1 (3.4.24.71)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
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- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
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- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Analytical Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pathology (AREA)
- Communicable Diseases (AREA)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1013616 | 1999-11-19 | ||
EP99203862 | 1999-11-19 | ||
NL1015356 | 2000-05-31 | ||
EP00201937 | 2000-05-31 | ||
PCT/EP2000/011532 WO2001036610A1 (en) | 1999-11-19 | 2000-11-17 | Human enzymes of the metalloprotease family |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60040089D1 true DE60040089D1 (de) | 2008-10-09 |
Family
ID=27440008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60040089T Expired - Lifetime DE60040089D1 (de) | 1999-11-19 | 2000-11-17 | Menschliches homolog aus der familie der metalloproteasen |
Country Status (13)
Country | Link |
---|---|
US (5) | US6855532B2 (de) |
EP (1) | EP1234025B1 (de) |
JP (1) | JP2003514525A (de) |
CN (1) | CN1250717C (de) |
AT (1) | ATE406438T1 (de) |
AU (1) | AU784327B2 (de) |
CA (1) | CA2392076A1 (de) |
DE (1) | DE60040089D1 (de) |
DK (1) | DK1234025T3 (de) |
ES (1) | ES2310527T3 (de) |
HK (1) | HK1052026A1 (de) |
IL (2) | IL149416A0 (de) |
WO (1) | WO2001036610A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020086405A1 (en) * | 2000-09-25 | 2002-07-04 | Inmaculada Silos-Santiago | 56638, a novel human neprilysin protease and uses thereof |
IL149416A0 (en) | 1999-11-19 | 2002-11-10 | Solvay Pharm Bv | Human enzymes of the metalloprotease family |
US6991916B2 (en) * | 2000-07-14 | 2006-01-31 | Pfizer Inc. | Compounds for the treatment of sexual dysfunction |
WO2003102544A2 (en) * | 2002-05-31 | 2003-12-11 | Cognosci, Inc. | Assays for measuring matrix metalloproteinase activities |
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2000
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- 2000-11-17 AU AU18582/01A patent/AU784327B2/en not_active Ceased
- 2000-11-17 AT AT00981279T patent/ATE406438T1/de active
- 2000-11-17 JP JP2001538489A patent/JP2003514525A/ja active Pending
- 2000-11-17 CA CA002392076A patent/CA2392076A1/en not_active Abandoned
- 2000-11-17 DE DE60040089T patent/DE60040089D1/de not_active Expired - Lifetime
- 2000-11-17 EP EP00981279A patent/EP1234025B1/de not_active Expired - Lifetime
- 2000-11-17 ES ES00981279T patent/ES2310527T3/es not_active Expired - Lifetime
- 2000-11-17 DK DK00981279T patent/DK1234025T3/da active
- 2000-11-17 WO PCT/EP2000/011532 patent/WO2001036610A1/en active IP Right Grant
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2002
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CN1399678A (zh) | 2003-02-26 |
CA2392076A1 (en) | 2001-05-25 |
US20030180877A1 (en) | 2003-09-25 |
JP2003514525A (ja) | 2003-04-22 |
IL149416A0 (en) | 2002-11-10 |
EP1234025B1 (de) | 2008-08-27 |
US20070148688A1 (en) | 2007-06-28 |
US7083965B2 (en) | 2006-08-01 |
IL149416A (en) | 2009-02-11 |
US20040224356A1 (en) | 2004-11-11 |
US7189525B2 (en) | 2007-03-13 |
ES2310527T3 (es) | 2009-01-16 |
CN1250717C (zh) | 2006-04-12 |
AU784327B2 (en) | 2006-03-09 |
ATE406438T1 (de) | 2008-09-15 |
WO2001036610A1 (en) | 2001-05-25 |
US6855532B2 (en) | 2005-02-15 |
US7312321B2 (en) | 2007-12-25 |
US20080070259A1 (en) | 2008-03-20 |
EP1234025A1 (de) | 2002-08-28 |
DK1234025T3 (da) | 2008-11-17 |
HK1052026A1 (en) | 2003-08-29 |
AU1858201A (en) | 2001-05-30 |
US20060205018A1 (en) | 2006-09-14 |
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