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DE60036723D1 - Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen - Google Patents

Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen

Info

Publication number
DE60036723D1
DE60036723D1 DE60036723T DE60036723T DE60036723D1 DE 60036723 D1 DE60036723 D1 DE 60036723D1 DE 60036723 T DE60036723 T DE 60036723T DE 60036723 T DE60036723 T DE 60036723T DE 60036723 D1 DE60036723 D1 DE 60036723D1
Authority
DE
Germany
Prior art keywords
mesoprogestines
hormone
prevention
treatment
gynecological disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60036723T
Other languages
English (en)
Other versions
DE60036723T2 (de
Inventor
Kristof Chwalisz
Walter Elger
Gerd Schubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Application granted granted Critical
Publication of DE60036723D1 publication Critical patent/DE60036723D1/de
Publication of DE60036723T2 publication Critical patent/DE60036723T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
DE60036723T 1999-08-31 2000-08-31 Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen Expired - Lifetime DE60036723T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38614199A 1999-08-31 1999-08-31
US386141 1999-08-31
PCT/US2000/023770 WO2001015679A2 (en) 1999-08-31 2000-08-31 Mesoprogestins for the treatment and prevention of benign hormone dependent gynecological disorders

Publications (2)

Publication Number Publication Date
DE60036723D1 true DE60036723D1 (de) 2007-11-22
DE60036723T2 DE60036723T2 (de) 2008-07-17

Family

ID=23524338

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60036723T Expired - Lifetime DE60036723T2 (de) 1999-08-31 2000-08-31 Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen

Country Status (34)

Country Link
EP (1) EP1229906B1 (de)
JP (1) JP2003535029A (de)
KR (3) KR20080066095A (de)
AR (1) AR025457A1 (de)
AT (1) ATE375160T1 (de)
AU (1) AU781840B2 (de)
BG (1) BG65817B1 (de)
BR (1) BR0014161A (de)
CA (1) CA2382580C (de)
CO (1) CO5200772A1 (de)
CZ (1) CZ2002704A3 (de)
DE (1) DE60036723T2 (de)
DK (1) DK1229906T3 (de)
EA (1) EA007854B1 (de)
EE (1) EE05172B1 (de)
ES (1) ES2295050T3 (de)
HR (1) HRP20020267A2 (de)
HU (1) HUP0202429A3 (de)
IL (1) IL148416A0 (de)
LT (1) LT5034B (de)
LV (1) LV12941B (de)
ME (1) MEP13808A (de)
MX (1) MXPA02002191A (de)
NO (1) NO20020999L (de)
NZ (1) NZ517471A (de)
PE (1) PE20010578A1 (de)
PL (1) PL198790B1 (de)
PT (1) PT1229906E (de)
RO (1) RO122179B1 (de)
RS (1) RS50283B (de)
SI (1) SI20852B (de)
SK (1) SK287192B6 (de)
UA (1) UA78184C2 (de)
WO (1) WO2001015679A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10236405A1 (de) 2002-08-02 2004-02-19 Schering Ag Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie
AU2003255355A1 (en) * 2002-08-02 2004-02-25 Schering Aktiengesellschaft Progesterone receptor modulators having an increased antigonadotropic activity for use in female fertility testing and hormone replacement therapy
US20040097591A1 (en) * 2002-11-18 2004-05-20 Kristof Chwalisz Use of selective progesterone receptor modulators for the treatment of androgen deficiency
DE102007011105A1 (de) 2007-03-02 2008-09-04 Bayer Schering Pharma Aktiengesellschaft Mineralcorticoid-Rezeptor-Antagonisten zur Behandlung von Endometriose
CN106890168A (zh) * 2009-06-17 2017-06-27 国立大学法人熊本大学 痛经的预防和/或治疗药
US8399432B2 (en) * 2009-10-27 2013-03-19 Lipogen Ltd. Compositions and methods of treatment for alleviating premenstrual syndrome symptoms
JP2022548314A (ja) * 2019-09-23 2022-11-17 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 妊娠を遷延させるためおよび月経または妊娠の合併症の処置の方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3633244A1 (de) 1986-09-26 1988-03-31 Schering Ag Antigestagene zur hemmung der uterinen prostaglandinsynthese
DE4332284C2 (de) 1993-09-20 1997-05-28 Jenapharm Gmbh 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4332283A1 (de) * 1993-09-20 1995-04-13 Jenapharm Gmbh Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5681817A (en) * 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
US5576310A (en) * 1994-09-20 1996-11-19 Jenapharm Gmbh 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds
WO1996019458A2 (en) * 1994-12-22 1996-06-27 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
US5693647A (en) * 1994-12-22 1997-12-02 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
KR100370908B1 (ko) 1995-02-02 2003-04-10 쉐링 악티엔게젤샤프트 기능부전성자궁출혈치료용약제의제조에유용한프로게스테론길항제
DE19604231A1 (de) * 1996-01-29 1997-07-31 Schering Ag Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen
EP0900234B1 (de) * 1996-05-01 2000-07-05 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 21-substituierte progesteron derivate als antigestagene
WO1998005679A2 (en) * 1996-08-05 1998-02-12 Duke University Mixed agonists of the progesterone receptor and assays therefor
DE19809845A1 (de) * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
WO2000042031A2 (en) * 1999-01-14 2000-07-20 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
EP1175422A2 (de) * 1999-05-04 2002-01-30 Ligand Pharmaceuticals Incorporated Tetracyclische progesteronrezeptor-modulator-verbindungen und verfahren

Also Published As

Publication number Publication date
YU14002A (sh) 2006-01-16
BG65817B1 (bg) 2010-01-29
CA2382580C (en) 2009-05-19
HUP0202429A3 (en) 2004-04-28
DE60036723T2 (de) 2008-07-17
CA2382580A1 (en) 2001-03-08
ATE375160T1 (de) 2007-10-15
JP2003535029A (ja) 2003-11-25
AR025457A1 (es) 2002-11-27
NO20020999L (no) 2002-03-14
KR100864547B1 (ko) 2008-10-20
DK1229906T3 (da) 2008-02-11
NZ517471A (en) 2004-02-27
PT1229906E (pt) 2008-01-18
CO5200772A1 (es) 2002-09-27
PL198790B1 (pl) 2008-07-31
MXPA02002191A (es) 2002-09-30
SK287192B6 (sk) 2010-02-08
KR20070058023A (ko) 2007-06-07
RS50283B (sr) 2009-09-08
RO122179B1 (ro) 2009-02-27
HRP20020267A2 (en) 2004-04-30
EA200200282A1 (ru) 2002-10-31
LT5034B (lt) 2003-07-25
BG106442A (bg) 2002-09-30
EP1229906B1 (de) 2007-10-10
KR100755109B1 (ko) 2007-09-04
PL353930A1 (en) 2003-12-15
AU6946600A (en) 2001-03-26
WO2001015679A2 (en) 2001-03-08
NO20020999D0 (no) 2002-02-28
PE20010578A1 (es) 2001-06-04
WO2001015679A3 (en) 2001-11-22
KR20020027616A (ko) 2002-04-13
ES2295050T3 (es) 2008-04-16
KR20080066095A (ko) 2008-07-15
IL148416A0 (en) 2002-09-12
SI20852A (sl) 2002-10-31
CZ2002704A3 (cs) 2003-02-12
LT2002031A (en) 2003-02-25
EE05172B1 (et) 2009-06-15
SK2992002A3 (en) 2002-07-02
EP1229906A2 (de) 2002-08-14
UA78184C2 (en) 2007-03-15
EA007854B1 (ru) 2007-02-27
HUP0202429A2 (en) 2002-10-28
LV12941B (en) 2003-06-20
AU781840B2 (en) 2005-06-16
SI20852B (sl) 2009-06-30
EE200200104A (et) 2003-04-15
BR0014161A (pt) 2002-05-21
MEP13808A (en) 2010-06-10

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: BAYER SCHERING PHARMA AKIENGESELLSCHAFT, 13353, DE

8364 No opposition during term of opposition