DE60027928D1 - MENSCHLICHES, GEBäRMUTTERKREBS-SPEZIFISCHES SUPPRESSORPROTEIN, FüR DAS PROTEIN KODIERES POLYNUKLEOTID, MIT DEM POLYNUKLEOTID TRANSFORMIERTE ZELLE UND VERFAHREN ZUR UNTERDRüCKUNG DER PROLIFERATION VON KREBSZELLEN UNTER VERWENDUNG DES EXPRESSIONSVEKTORS - Google Patents
MENSCHLICHES, GEBäRMUTTERKREBS-SPEZIFISCHES SUPPRESSORPROTEIN, FüR DAS PROTEIN KODIERES POLYNUKLEOTID, MIT DEM POLYNUKLEOTID TRANSFORMIERTE ZELLE UND VERFAHREN ZUR UNTERDRüCKUNG DER PROLIFERATION VON KREBSZELLEN UNTER VERWENDUNG DES EXPRESSIONSVEKTORSInfo
- Publication number
- DE60027928D1 DE60027928D1 DE60027928T DE60027928T DE60027928D1 DE 60027928 D1 DE60027928 D1 DE 60027928D1 DE 60027928 T DE60027928 T DE 60027928T DE 60027928 T DE60027928 T DE 60027928T DE 60027928 D1 DE60027928 D1 DE 60027928D1
- Authority
- DE
- Germany
- Prior art keywords
- polynucleotide
- expression vector
- cancer
- proliferation
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 201000011510 cancer Diseases 0.000 title abstract 5
- 102000040430 polynucleotide Human genes 0.000 title abstract 5
- 108091033319 polynucleotide Proteins 0.000 title abstract 5
- 239000002157 polynucleotide Substances 0.000 title abstract 5
- 239000013604 expression vector Substances 0.000 title abstract 4
- 230000035755 proliferation Effects 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title 2
- 108090000623 proteins and genes Proteins 0.000 title 2
- 102000001742 Tumor Suppressor Proteins Human genes 0.000 abstract 2
- 108010040002 Tumor Suppressor Proteins Proteins 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000000225 tumor suppressor protein Substances 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 210000004102 animal cell Anatomy 0.000 abstract 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2000-0021897A KR100426455B1 (ko) | 2000-04-25 | 2000-04-25 | 인간 암 억제 유전자, 이에 의해 코딩되는 단백질, 이를포함하는 발현 벡터 및 이 벡터로 형질전환된 세포 |
KR2000021897 | 2000-04-25 | ||
PCT/KR2000/001406 WO2001081387A1 (en) | 2000-04-25 | 2000-12-04 | Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide and method for suppressing proliferation of cancer cell using the expression vector |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60027928D1 true DE60027928D1 (de) | 2006-06-14 |
DE60027928T2 DE60027928T2 (de) | 2007-01-04 |
Family
ID=36251014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60027928T Expired - Fee Related DE60027928T2 (de) | 2000-04-25 | 2000-12-04 | MENSCHLICHES, ZERVIKALKREBS-SPEZIFISCHES SUPPRESSORPROTEIN, FüR DAS PROTEIN CODIERENDES POLYNUKLEOTID, MIT DEM POLYNUKLEOTID TRANSFORMIERTE ZELLE UND VERFAHREN ZUR UNTERDRÜCKUNG DER PROLIFERATION VON KREBSZELLEN UNTER VERWENDUNG DES EXPRESSIONSVEKTORS |
Country Status (11)
Country | Link |
---|---|
US (1) | US6977296B2 (de) |
EP (1) | EP1282641B1 (de) |
JP (1) | JP3749182B2 (de) |
KR (1) | KR100426455B1 (de) |
CN (1) | CN1216909C (de) |
AT (1) | ATE325812T1 (de) |
AU (1) | AU2001220255A1 (de) |
CA (1) | CA2405983A1 (de) |
DE (1) | DE60027928T2 (de) |
HK (1) | HK1060136A1 (de) |
WO (1) | WO2001081387A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100426452B1 (ko) * | 2001-01-02 | 2004-04-13 | 김진우 | 인간 원암 유전자로 형질전환된 포유동물 및 이 유전자를이용한 유방암, 신장암, 난소암 또는 위암 진단용 키트 |
EP1390518B1 (de) * | 2001-04-23 | 2004-10-06 | Amaxa GmbH | Pufferlössung für die elektroporation und verfahren umfassend die verwendung derselben |
KR100434591B1 (ko) * | 2002-04-16 | 2004-06-04 | 김진우 | 인간 암 억제 유전자, 이에 의해 코딩되는 단백질, 이를포함하는 발현 벡터 및 이 벡터로 형질전환된 세포 |
KR100664589B1 (ko) * | 2004-12-28 | 2007-01-04 | 김현기 | 인간 암 억제 유전자, 이에 의해 코딩되는 단백질, 및이를 포함하는 발현 벡터 |
WO2008060776A2 (en) * | 2006-10-03 | 2008-05-22 | University Of Medicine And Dentistry Of New Jersey | Atap peptides, nucleic acids encoding the same and associated methods of use |
KR101815322B1 (ko) * | 2010-01-12 | 2018-01-05 | 서울대학교산학협력단 | 항암 펩타이드 서열 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR960034413A (ko) * | 1995-03-24 | 1996-10-22 | 권계홍 | 아폽토시스 조절 유전자 |
AU1873097A (en) * | 1996-02-14 | 1997-09-02 | New England Deaconess Hospital Corporation | Gene therapy of entothelial cells with anti-apoptotic proteins for transplantation and inflammatory conditions |
WO1999061612A1 (en) * | 1998-05-28 | 1999-12-02 | Incyte Pharmaceuticals, Inc. | Tumor suppressor |
CA2296792A1 (en) * | 1999-02-26 | 2000-08-26 | Genset S.A. | Expressed sequence tags and encoded human proteins |
-
2000
- 2000-04-25 KR KR10-2000-0021897A patent/KR100426455B1/ko not_active IP Right Cessation
- 2000-12-04 EP EP00983508A patent/EP1282641B1/de not_active Expired - Lifetime
- 2000-12-04 AT AT00983508T patent/ATE325812T1/de not_active IP Right Cessation
- 2000-12-04 CA CA002405983A patent/CA2405983A1/en not_active Abandoned
- 2000-12-04 WO PCT/KR2000/001406 patent/WO2001081387A1/en active IP Right Grant
- 2000-12-04 DE DE60027928T patent/DE60027928T2/de not_active Expired - Fee Related
- 2000-12-04 JP JP2001578474A patent/JP3749182B2/ja not_active Expired - Fee Related
- 2000-12-04 CN CN008193843A patent/CN1216909C/zh not_active Expired - Fee Related
- 2000-12-04 US US10/257,819 patent/US6977296B2/en not_active Expired - Fee Related
- 2000-12-04 AU AU2001220255A patent/AU2001220255A1/en not_active Abandoned
-
2004
- 2004-04-21 HK HK04102793A patent/HK1060136A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR20010097640A (ko) | 2001-11-08 |
CA2405983A1 (en) | 2001-11-01 |
EP1282641A1 (de) | 2003-02-12 |
ATE325812T1 (de) | 2006-06-15 |
EP1282641A4 (de) | 2004-05-19 |
CN1216909C (zh) | 2005-08-31 |
DE60027928T2 (de) | 2007-01-04 |
EP1282641B1 (de) | 2006-05-10 |
JP2003534783A (ja) | 2003-11-25 |
US20040086974A1 (en) | 2004-05-06 |
CN1451016A (zh) | 2003-10-22 |
AU2001220255A1 (en) | 2001-11-07 |
JP3749182B2 (ja) | 2006-02-22 |
US6977296B2 (en) | 2005-12-20 |
HK1060136A1 (en) | 2004-07-30 |
WO2001081387A1 (en) | 2001-11-01 |
KR100426455B1 (ko) | 2004-04-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT87562A (pt) | Procede de expression de la proapolipoproteine a-i humaine | |
EP1548032A4 (de) | Kdr-peptide und diese enthaltende impfstoffe | |
BG109433A (en) | RET (RetL) Lead for Stimulating Nerve and Rat Growth | |
CA2461443A1 (en) | Nucleic acid and amino acid sequences encoding high-level expressor factor viii polypeptides and methods of use | |
EP2114431A4 (de) | Zusammensetzung mit arazym zur prävention und behandlung von krebs | |
BR9912279A (pt) | Uso de uteroglobina humana recombinante no tratamento de condições inflamatórias e fibróticas | |
CA2449284A1 (en) | Alpha-fetoprotein peptides and uses thereof | |
DE60027928D1 (de) | MENSCHLICHES, GEBäRMUTTERKREBS-SPEZIFISCHES SUPPRESSORPROTEIN, FüR DAS PROTEIN KODIERES POLYNUKLEOTID, MIT DEM POLYNUKLEOTID TRANSFORMIERTE ZELLE UND VERFAHREN ZUR UNTERDRüCKUNG DER PROLIFERATION VON KREBSZELLEN UNTER VERWENDUNG DES EXPRESSIONSVEKTORS | |
ATE356145T1 (de) | Polypeptide zur regenerierung des nervensystems | |
AU5327198A (en) | Nucleotide sequence coding for a flavin-containing monooxygenase, corresponding protein and their applications in the fields of diagnosis and therapy | |
AR025482A1 (es) | Secuencia de adn que codifica una proteina capaz de ligarse a traf; vector que comprende dicha secuencia; celulas huespedes transformadas con dicho vector;proteinas iren codificadas por dicha secuencia; metodo para producir dicha proteina; anticuerpos especificos para dichas proteinas; metodo para m | |
MX9806628A (es) | Gen de respuesta de diferenciacion terminal mieloide humana novedoso. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |