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DE60025494D1 - EPOTHILONE COMPOSITIONS - Google Patents

EPOTHILONE COMPOSITIONS

Info

Publication number
DE60025494D1
DE60025494D1 DE60025494T DE60025494T DE60025494D1 DE 60025494 D1 DE60025494 D1 DE 60025494D1 DE 60025494 T DE60025494 T DE 60025494T DE 60025494 T DE60025494 T DE 60025494T DE 60025494 D1 DE60025494 D1 DE 60025494D1
Authority
DE
Germany
Prior art keywords
epothilone
compositions
liposomal compositions
provides liposomal
provides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60025494T
Other languages
German (de)
Other versions
DE60025494T2 (en
Inventor
Jean-Claude Sonntag
Markus Wartmann
Karl-Heinz Altmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10858600&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60025494(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE60025494D1 publication Critical patent/DE60025494D1/en
Application granted granted Critical
Publication of DE60025494T2 publication Critical patent/DE60025494T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

This invention provides liposomal compositions comprising an epothilone.
DE60025494T 1999-08-04 2000-08-02 EPOTHILONE COMPOSITIONS Expired - Lifetime DE60025494T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9918429 1999-08-04
GBGB9918429.3A GB9918429D0 (en) 1999-08-04 1999-08-04 Organic compounds
PCT/EP2000/007488 WO2001010412A1 (en) 1999-08-04 2000-08-02 Epothilone compositions

Publications (2)

Publication Number Publication Date
DE60025494D1 true DE60025494D1 (en) 2006-04-06
DE60025494T2 DE60025494T2 (en) 2006-07-27

Family

ID=10858600

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60025494T Expired - Lifetime DE60025494T2 (en) 1999-08-04 2000-08-02 EPOTHILONE COMPOSITIONS

Country Status (8)

Country Link
EP (1) EP1198225B1 (en)
AT (1) ATE315380T1 (en)
AU (1) AU6279500A (en)
DE (1) DE60025494T2 (en)
DK (1) DK1198225T3 (en)
ES (1) ES2254203T3 (en)
GB (1) GB9918429D0 (en)
WO (1) WO2001010412A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204388B1 (en) 1996-12-03 2001-03-20 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
JP4579351B2 (en) 1996-12-03 2010-11-10 スローン−ケッタリング インスティトュート フォア キャンサー リサーチ Synthesis of epothilone and its intermediates and analogs and uses thereof
US6589968B2 (en) 2001-02-13 2003-07-08 Kosan Biosciences, Inc. Epothilone compounds and methods for making and using the same
US6893859B2 (en) 2001-02-13 2005-05-17 Kosan Biosciences, Inc. Epothilone derivatives and methods for making and using the same
TWI341728B (en) * 2002-01-14 2011-05-11 Novartis Ag Combinations comprising epothilones and anti-metabolites
CN1649585A (en) * 2002-05-01 2005-08-03 诺瓦提斯公司 Epothilone derivative for the treatment of hepatoma and other cancer diseases
DK2286795T3 (en) 2002-06-26 2017-02-06 Syncore Biotechnology Co Ltd PROCEDURE FOR PREPARING A Cationic LIPOSOMAL PREPARATION INCLUDING A LIPOPHIL COMPOUND
CA2501610C (en) * 2002-10-11 2012-01-03 Dana-Farber Cancer Institute Inc Epothilone derivatives for the treatment of multiple myeloma
EP1562941B1 (en) 2002-11-07 2009-12-23 Kosan Biosciences, Inc. Trans-9,10-dehydroepothilone c and d, analogs thereof and methos of making the same
US7691838B2 (en) 2003-05-30 2010-04-06 Kosan Biosciences Incorporated Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics
RU2007144195A (en) 2005-04-29 2009-06-10 Козан Байосайенсиз Инкорпорейтед (Us) METHOD FOR TREATING MULTIPLE MYELOMA USING 17-AAG OR 17-AG OR THE PROCEDURE OF ANY OF THEM
AU2010227549B2 (en) 2009-03-25 2014-02-27 Novartis Ag Pharmaceutical composition containing a drug and siRNA
JP5881254B2 (en) 2010-05-18 2016-03-09 セルリアン・ファーマ・インコーポレイテッド Compositions and methods for the treatment of autoimmune and other diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515016B2 (en) * 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis

Also Published As

Publication number Publication date
GB9918429D0 (en) 1999-10-06
ES2254203T3 (en) 2006-06-16
ATE315380T1 (en) 2006-02-15
EP1198225B1 (en) 2006-01-11
DK1198225T3 (en) 2006-03-27
DE60025494T2 (en) 2006-07-27
EP1198225A1 (en) 2002-04-24
AU6279500A (en) 2001-03-05
WO2001010412A1 (en) 2001-02-15

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8365 Fully valid after opposition proceedings
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN