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DE60016284D1 - NON-INVASIVE DETERMINATION OF HEART VOLUME, PULMONARY BLOOD FLOW, AND BLOOD GAS CONTENT - Google Patents

NON-INVASIVE DETERMINATION OF HEART VOLUME, PULMONARY BLOOD FLOW, AND BLOOD GAS CONTENT

Info

Publication number
DE60016284D1
DE60016284D1 DE60016284T DE60016284T DE60016284D1 DE 60016284 D1 DE60016284 D1 DE 60016284D1 DE 60016284 T DE60016284 T DE 60016284T DE 60016284 T DE60016284 T DE 60016284T DE 60016284 D1 DE60016284 D1 DE 60016284D1
Authority
DE
Germany
Prior art keywords
blood flow
blood
gas content
subject
gas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60016284T
Other languages
German (de)
Other versions
DE60016284T2 (en
Inventor
A Orr
Kai Kuck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTC Technology Inc
Original Assignee
NTC Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NTC Technology Inc filed Critical NTC Technology Inc
Publication of DE60016284D1 publication Critical patent/DE60016284D1/en
Application granted granted Critical
Publication of DE60016284T2 publication Critical patent/DE60016284T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/029—Measuring blood output from the heart, e.g. minute volume
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N2001/2244—Exhaled gas, e.g. alcohol detecting

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Emergency Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Methods for noninvasively determining a pulmonary capillary blood flow or a cardiac output of a subject include determining data of the amount of gas exchanged between blood and gas in lungs of the subject, as well as data of an indicator of the content of the gas in blood of the subject. Such a determination may be made during two or more different states of ventilation. A geometric relationship is identified between data points, with any data points outlying the geometric relationship being disregarded. The remaining data points may be used to estimate or calculate a measure of pulmonary capillary blood flow or cardiac output. Systems that include elements that are configured to effect such methods are also disclosed.
DE60016284T 2000-02-22 2000-09-01 NONINVASIVE DETERMINATION OF HEART TIME VOLUME, PULMONARY BLOOD FLOW AND BLOOD GAS CONTENT Expired - Lifetime DE60016284T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/510,702 US6540689B1 (en) 2000-02-22 2000-02-22 Methods for accurately, substantially noninvasively determining pulmonary capillary blood flow, cardiac output, and mixed venous carbon dioxide content
US510702 2000-02-22
PCT/US2000/024044 WO2001062148A1 (en) 2000-02-22 2000-09-01 Noninvasive determination of cardiac output, pulmonary blood flow, and blood gas content

Publications (2)

Publication Number Publication Date
DE60016284D1 true DE60016284D1 (en) 2004-12-30
DE60016284T2 DE60016284T2 (en) 2005-12-15

Family

ID=24031821

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60016284T Expired - Lifetime DE60016284T2 (en) 2000-02-22 2000-09-01 NONINVASIVE DETERMINATION OF HEART TIME VOLUME, PULMONARY BLOOD FLOW AND BLOOD GAS CONTENT

Country Status (8)

Country Link
US (6) US6540689B1 (en)
EP (1) EP1257201B1 (en)
JP (1) JP3761465B2 (en)
AT (1) ATE282988T1 (en)
BR (1) BR0017131B1 (en)
DE (1) DE60016284T2 (en)
ES (1) ES2232490T3 (en)
WO (1) WO2001062148A1 (en)

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Also Published As

Publication number Publication date
EP1257201B1 (en) 2004-11-24
US7074196B2 (en) 2006-07-11
BR0017131A (en) 2002-11-05
US20030181820A1 (en) 2003-09-25
US8398559B2 (en) 2013-03-19
US20020183643A1 (en) 2002-12-05
US20050177055A1 (en) 2005-08-11
US6540689B1 (en) 2003-04-01
US20060253038A1 (en) 2006-11-09
US8801625B2 (en) 2014-08-12
JP2003523248A (en) 2003-08-05
JP3761465B2 (en) 2006-03-29
ES2232490T3 (en) 2005-06-01
US6955651B2 (en) 2005-10-18
WO2001062148A1 (en) 2001-08-30
US7025731B2 (en) 2006-04-11
EP1257201A1 (en) 2002-11-20
BR0017131B1 (en) 2010-05-04
ATE282988T1 (en) 2004-12-15
US20060129055A1 (en) 2006-06-15
DE60016284T2 (en) 2005-12-15

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