[go: up one dir, main page]

DE60010662D1 - Kombinationen von formoterol und fluticasonpropionat für asthma - Google Patents

Kombinationen von formoterol und fluticasonpropionat für asthma

Info

Publication number
DE60010662D1
DE60010662D1 DE60010662T DE60010662T DE60010662D1 DE 60010662 D1 DE60010662 D1 DE 60010662D1 DE 60010662 T DE60010662 T DE 60010662T DE 60010662 T DE60010662 T DE 60010662T DE 60010662 D1 DE60010662 D1 DE 60010662D1
Authority
DE
Germany
Prior art keywords
fluticasonpropionate
formoterol
asthma
combinations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE60010662T
Other languages
English (en)
Other versions
DE60010662T2 (de
Inventor
Guy Clarke
Luke Danahay
Francis Hassan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10848051&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60010662(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of DE60010662D1 publication Critical patent/DE60010662D1/de
Publication of DE60010662T2 publication Critical patent/DE60010662T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60010662T 1999-02-18 2000-02-16 Kombinationen von formoterol und fluticasonpropionat für asthma Revoked DE60010662T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9903759 1999-02-18
GBGB9903759.0A GB9903759D0 (en) 1999-02-18 1999-02-18 Organic compounds
PCT/EP2000/001270 WO2000048587A1 (en) 1999-02-18 2000-02-16 Combinations of formoterol and fluticasone propionate for asthma

Publications (2)

Publication Number Publication Date
DE60010662D1 true DE60010662D1 (de) 2004-06-17
DE60010662T2 DE60010662T2 (de) 2005-05-19

Family

ID=10848051

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60010662T Revoked DE60010662T2 (de) 1999-02-18 2000-02-16 Kombinationen von formoterol und fluticasonpropionat für asthma

Country Status (32)

Country Link
US (4) US20020103260A1 (de)
EP (1) EP1152753B1 (de)
JP (1) JP2002537249A (de)
KR (2) KR20010102205A (de)
CN (1) CN1339965A (de)
AR (1) AR022609A1 (de)
AT (1) ATE266393T1 (de)
AU (1) AU758999B2 (de)
BR (1) BR0008276A (de)
CA (1) CA2368537A1 (de)
CO (1) CO5140098A1 (de)
CZ (1) CZ20012976A3 (de)
DE (1) DE60010662T2 (de)
DK (1) DK1152753T3 (de)
ES (1) ES2220411T3 (de)
GB (1) GB9903759D0 (de)
HK (1) HK1042429A1 (de)
HU (1) HUP0200852A3 (de)
ID (1) ID29437A (de)
IL (1) IL144061A (de)
MY (1) MY126768A (de)
NO (1) NO20013987D0 (de)
NZ (1) NZ513526A (de)
PE (1) PE20001545A1 (de)
PL (1) PL349856A1 (de)
PT (1) PT1152753E (de)
RU (1) RU2249454C2 (de)
SK (1) SK11842001A3 (de)
TR (1) TR200102110T2 (de)
TW (1) TWI229601B (de)
WO (1) WO2000048587A1 (de)
ZA (1) ZA200105391B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
GB2385596B (en) * 1999-09-11 2004-03-03 Glaxo Group Ltd Container for pharmaceutical formulation of fluticasone propionate
GB2392164B (en) * 1999-09-11 2004-04-07 Glaxo Group Ltd Pharmaceutical formulation of fluticasone propionate
IT1317904B1 (it) 1999-09-11 2003-07-15 Glaxo Group Ltd Formulazione farmaceutica di propionato di fluticasone.
WO2001078735A1 (en) * 2000-04-13 2001-10-25 Innovata Biomed Limited Medicaments for treating respiratory disorders comprising formoterol and fluticasone
GB0009591D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medical combinations
GB0012260D0 (en) 2000-05-19 2000-07-12 Astrazeneca Ab Novel composition
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
FI20002216A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
FI20002215A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
MXPA03007017A (es) * 2001-02-06 2004-09-13 Innovata Biomed Ltd Medicamentos.
GB0106031D0 (en) * 2001-03-12 2001-05-02 Glaxo Group Ltd Use
CN100496608C (zh) * 2001-03-30 2009-06-10 洁垢技术有限公司 药用气溶胶制剂
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US7931022B2 (en) 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
DE60321311D1 (de) † 2002-02-04 2008-07-10 Glaxo Group Ltd Zubereitung zur inhalation enthaltend ein glucocorticoid und einen beta 2-adrenorezeptor agonisten
EP1757281A3 (de) * 2002-02-04 2009-07-15 Glaxo Group Limited Zubereitung zur Inhalation enthaltend ein Glucocorticoid und einen Beta 2-Adrenorezeptor Agonisten
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
NZ538965A (en) * 2002-08-21 2006-11-30 Norton Healthcare Ltd Dry powder inhalation compositions
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
JP4744876B2 (ja) * 2002-08-21 2011-08-10 ノートン・ヘルスケアー リミテッド 乾燥粉末吸入組成物の製造方法
AU2003263717A1 (en) * 2002-09-25 2004-04-19 Astrazeneca Ab A COMBINATION OF A LONG-ACTING Beta2-AGONIST AND A GLUCOCORTICOSTEROID IN THE TREATMENT OF FIBROTIC DISEASES
SE526850C2 (sv) * 2003-06-19 2005-11-08 Microdrug Ag Farmaceutisk kombinerad torr pulverdos separerade på gemensam dosbädd
SE527189C2 (sv) * 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser för formaterol och ett antikolinergiskt medel
SE527069C2 (sv) * 2003-06-19 2005-12-13 Mederio Ag Förfarande och anordning för administrering av läkemedelspulver
SE527200C2 (sv) * 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser av formaterol och fluticason
SE526509C2 (sv) * 2003-06-19 2005-09-27 Microdrug Ag Kombinerade doser av formoterol och budesonid separerade på en gemensam dosbädd
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
GB0323685D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
GB0323684D0 (en) 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
GB0617171D0 (en) * 2006-08-31 2006-10-11 Generics Uk Ltd Novel compositions and methods
WO2008137446A1 (en) * 2007-05-03 2008-11-13 Trustees Of Boston University Methods and compositions for the treatment of respiratory disease
RU2751771C2 (ru) 2009-05-29 2021-07-16 Перл Терапьютикс, Инк. Композиции для респираторной доставки активных веществ и связанные с ними способы и системы
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
GB0918150D0 (en) * 2009-10-16 2009-12-02 Jagotec Ag Improved formulations
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
WO2011093811A2 (en) * 2010-01-29 2011-08-04 Mahmut Bilgic Pharmaceutical preparations comprising formoterol and fluticasone
CN103269694A (zh) * 2010-10-12 2013-08-28 西普拉有限公司 药物组合物
CA2835927A1 (en) * 2011-05-17 2012-11-22 Pearl Therapeutics, Inc. Compositions, methods & systems for respiratory delivery of two or more active agents
JP2015512929A (ja) * 2012-04-11 2015-04-30 シプラ・リミテッド 医薬組成物
JP6454323B2 (ja) 2013-03-15 2019-01-16 パール セラピューティクス，インコーポレイテッド 粒子状結晶性材料のコンディショニングのための方法及びシステム

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL95590A (en) * 1989-09-08 1996-06-18 Glaxo Group Ltd Medicinal preparations containing Salmetrol and Pluticasone Propionate
SE9302777D0 (sv) * 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
DE69232462T2 (de) * 1991-12-18 2002-10-10 Astrazeneca Ab, Soedertaelje Formoterol und budesonide enthaltende zusammensetzung
GB9426252D0 (en) * 1994-12-24 1995-02-22 Glaxo Group Ltd Pharmaceutical composition
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
ATE219355T1 (de) * 1997-02-05 2002-07-15 Jago Res Ag Medizinische aerosolformulierungen
KR100386055B1 (ko) * 1997-03-20 2003-06-09 쉐링 코포레이션 분말 응집물의 제조방법

Also Published As

Publication number Publication date
ZA200105391B (en) 2002-06-21
ID29437A (id) 2001-08-30
ES2220411T3 (es) 2004-12-16
CN1339965A (zh) 2002-03-13
NO20013987L (no) 2001-08-16
JP2002537249A (ja) 2002-11-05
SK11842001A3 (sk) 2001-12-03
DE60010662T2 (de) 2005-05-19
US20050287079A1 (en) 2005-12-29
CZ20012976A3 (cs) 2001-11-14
HK1042429A1 (en) 2002-08-16
AU2911500A (en) 2000-09-04
CO5140098A1 (es) 2002-03-22
EP1152753B1 (de) 2004-05-12
CA2368537A1 (en) 2000-08-24
TR200102110T2 (tr) 2001-10-22
IL144061A (en) 2005-12-18
GB9903759D0 (en) 1999-04-14
IL144061A0 (en) 2002-04-21
US20020103260A1 (en) 2002-08-01
NZ513526A (en) 2004-01-30
KR20010102205A (ko) 2001-11-15
DK1152753T3 (da) 2004-08-16
PE20001545A1 (es) 2001-01-29
WO2000048587A1 (en) 2000-08-24
TWI229601B (en) 2005-03-21
AR022609A1 (es) 2002-09-04
EP1152753A1 (de) 2001-11-14
BR0008276A (pt) 2001-11-06
US20040101487A1 (en) 2004-05-27
RU2249454C2 (ru) 2005-04-10
NO20013987D0 (no) 2001-08-16
AU758999B2 (en) 2003-04-03
PL349856A1 (en) 2002-09-23
US20100034890A1 (en) 2010-02-11
HUP0200852A2 (en) 2002-08-28
HUP0200852A3 (en) 2004-04-28
MY126768A (en) 2006-10-31
ATE266393T1 (de) 2004-05-15
KR20070104955A (ko) 2007-10-29
PT1152753E (pt) 2004-09-30

Similar Documents

Publication Publication Date Title
DE60010662D1 (de) Kombinationen von formoterol und fluticasonpropionat für asthma
EE04297B1 (et) Budesoniidi ja formoterooli uus kasutamine
ATE252832T1 (de) Kombinationen aus herbiziden und safenern
HUP0200142A2 (en) Combinations of formoterol and mometasone furoate for asthma
DE69908339D1 (de) Endgerät für bibliotheken und dergleichen
NO20022334L (no) Ny sammensetning og anvendelse
DE60012644D1 (de) Kombination aus Aescin und Dextran Sulphat
ATE241988T1 (de) Neue kombination von loteprednol und antihistaminika
DE59912795D1 (de) Substituierte Benzamide und ihre Verwendung als Immunmodulatoren
DE69904731D1 (de) Feinzerkleinerer und feinzerkleinerungsverfahren
DE60125985D1 (de) Austrockungungsmittel für stengel und blätter
ID30430A (id) Senyawa-senyawa dan metode-metode untuk pengobatan gangguan-gangguan asma, alergi dan inflamasi
DE69934889D1 (de) Herstellung und reinigung von diboranen
ATE227724T1 (de) Muscarinagonisten und antagonisten
DE69826008D1 (de) Mischungen aus polyimiden und elastomeren
DE69917261D1 (de) Photoinitiatoren und ihre verwendungen
ID28368A (id) Tanda-tanda mikrosatelite tumbuhan dan metode terhadap penggunaannya
DE69932653D1 (de) Dielektrisches Filter und dielektrischer Duplexer
NO996438D0 (no) Ny kombinasjon av astmamedikamenter
DE69900802D1 (de) MnMgCuZn-Ferrit und dessen Verwendung
DE60131595D1 (de) Trennwand für Aufenthaltsräume und dessen Gebrauch
DE69825320D1 (de) Wärmeisolationsmaterial für gebäude und anwendung dessselben
DE69803634D1 (de) Herstellung von Phenol und dessen Derivaten
ATA12862000A (de) Gas- und/oder flüssigkeitsdurchlässiges filtermaterial
DE60236080D1 (de) Verhinderung des verlusts von portoguthaben für frankiermaschinen und pc-frankiermaschinen

Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation