DE60008712D1 - Verfahren zur detektion von endometriosis - Google Patents
Verfahren zur detektion von endometriosisInfo
- Publication number
- DE60008712D1 DE60008712D1 DE60008712T DE60008712T DE60008712D1 DE 60008712 D1 DE60008712 D1 DE 60008712D1 DE 60008712 T DE60008712 T DE 60008712T DE 60008712 T DE60008712 T DE 60008712T DE 60008712 D1 DE60008712 D1 DE 60008712D1
- Authority
- DE
- Germany
- Prior art keywords
- detecting
- eosinophil peroxidase
- component
- treating endometriosis
- targeting molecules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 201000009273 Endometriosis Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 108010092408 Eosinophil Peroxidase Proteins 0.000 abstract 3
- 102000044708 Eosinophil peroxidases Human genes 0.000 abstract 3
- 230000008685 targeting Effects 0.000 abstract 3
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6871—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting an enzyme
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1075—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against an enzyme
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/364—Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Optics & Photonics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12747799P | 1999-04-02 | 1999-04-02 | |
PCT/US2000/008581 WO2000059547A2 (en) | 1999-04-02 | 2000-03-31 | Method of detecting endometriosis |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60008712D1 true DE60008712D1 (de) | 2004-04-08 |
Family
ID=22430337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60008712T Expired - Lifetime DE60008712D1 (de) | 1999-04-02 | 2000-03-31 | Verfahren zur detektion von endometriosis |
Country Status (8)
Country | Link |
---|---|
US (1) | US6540980B1 (de) |
EP (1) | EP1169064B1 (de) |
JP (1) | JP2002541124A (de) |
AT (1) | ATE260678T1 (de) |
AU (1) | AU4056000A (de) |
CA (1) | CA2366774A1 (de) |
DE (1) | DE60008712D1 (de) |
WO (1) | WO2000059547A2 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7833528B2 (en) * | 1998-06-22 | 2010-11-16 | Immunomedics, Inc. | Use of multispecific, non-covalent complexes for targeted delivery of therapeutics |
US7138103B2 (en) * | 1998-06-22 | 2006-11-21 | Immunomedics, Inc. | Use of bi-specific antibodies for pre-targeting diagnosis and therapy |
US6962702B2 (en) * | 1998-06-22 | 2005-11-08 | Immunomedics Inc. | Production and use of novel peptide-based agents for use with bi-specific antibodies |
EP1914244B1 (de) | 1999-04-09 | 2013-05-29 | Kyowa Hakko Kirin Co., Ltd. | Verfahren zur Modulation der Aktivität funktioneller Immunmoleküle |
US7897140B2 (en) * | 1999-12-23 | 2011-03-01 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
WO2004002476A2 (en) | 2002-06-27 | 2004-01-08 | Health Research, Inc. | Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy |
WO2004005289A2 (en) * | 2002-07-02 | 2004-01-15 | Health Research, Inc. | Efficient synthesis of pyropheophorbide a and its derivatives |
WO2004082626A2 (en) * | 2003-03-18 | 2004-09-30 | Ethicon, Inc. | Aromatase inhibitor diagnosis and therapy |
US20050155097A1 (en) * | 2004-01-12 | 2005-07-14 | Lee James J. | Eosinophil-deficient transgenic animals |
US20060008876A1 (en) | 2004-07-07 | 2006-01-12 | Shami A S E | ME-5, ME-2, and EPP2: human protein antigens reactive with autoantibodies present in the serum of women suffering from endometriosis |
JP4954709B2 (ja) * | 2004-10-28 | 2012-06-20 | 協和発酵キリン株式会社 | 子宮内膜症治療剤 |
JP2009521512A (ja) * | 2005-12-23 | 2009-06-04 | ザ バーナム インスティテュート フォー メディカル リサーチ | 子宮内膜症細胞ターゲティングペプチドおよびその使用 |
US20080305967A1 (en) * | 2007-06-11 | 2008-12-11 | Juneau Biosciences, Llc | Genetic Markers Associated with Endometriosis and Use Thereof |
US20080306034A1 (en) * | 2007-06-11 | 2008-12-11 | Juneau Biosciences, Llc | Method of Administering a Therapeutic |
US8932993B1 (en) | 2007-06-11 | 2015-01-13 | Juneau Biosciences, LLC. | Method of testing for endometriosis and treatment therefor |
WO2010124101A2 (en) * | 2009-04-22 | 2010-10-28 | Juneau Biosciences, Llc | Genetic markers associated with endometriosis and use thereof |
WO2011126984A1 (en) * | 2010-04-05 | 2011-10-13 | University Of Utah Research Foundation | Mapping in vivo eosinophil activation in eosinophilic esophagitis |
KR20140102294A (ko) | 2011-12-13 | 2014-08-21 | 엔진아이씨 몰레큘러 딜리버리 피티와이 리미티드 | 뇌 종양에 대한 치료제의 전달을 위한 박테리아 유래된, 무손상 미니세포 |
DE102012002929A1 (de) | 2012-02-14 | 2013-08-14 | Jürgen Lewald | Minimalinvasives Verfahren für die Diagnose und die Therapieverlaufskontrolle der Endometriose |
US9434991B2 (en) | 2013-03-07 | 2016-09-06 | Juneau Biosciences, LLC. | Method of testing for endometriosis and treatment therefor |
GB202202919D0 (en) | 2022-03-02 | 2022-04-13 | Serac Healthcare Ltd | Methods for imaging integrin expression |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4782840A (en) * | 1984-03-02 | 1988-11-08 | Neoprobe Corporation | Method for locating, differentiating, and removing neoplasms |
US4932412A (en) * | 1986-12-18 | 1990-06-12 | Immunomedics, Inc. | Intraoperative and endoscopic tumor detection and therapy |
US5478725A (en) * | 1992-06-12 | 1995-12-26 | University Of Pennsylvania | αv β3 integrin as a predictor of endometriosis |
US5831035A (en) * | 1994-10-25 | 1998-11-03 | Curators Of The University Of Missouri | Antibody against human endometrial stromal cell glycoprotein |
US5843673A (en) * | 1994-10-25 | 1998-12-01 | Curators Of The University Of Missouri | Method of screening for endometriosis |
US5567828A (en) | 1995-06-07 | 1996-10-22 | Eli Lilly And Company | Compounds and compositions with nitrogen-containing non-basic side |
CA2214196A1 (en) | 1996-09-26 | 1998-03-26 | Eli Lilly And Company | Benzo[b]indeno[2,1-d]thiophene compounds, intermediates, processes, compositions and methods |
-
2000
- 2000-03-31 AT AT00919954T patent/ATE260678T1/de not_active IP Right Cessation
- 2000-03-31 DE DE60008712T patent/DE60008712D1/de not_active Expired - Lifetime
- 2000-03-31 EP EP00919954A patent/EP1169064B1/de not_active Expired - Lifetime
- 2000-03-31 US US09/541,030 patent/US6540980B1/en not_active Expired - Lifetime
- 2000-03-31 JP JP2000609108A patent/JP2002541124A/ja active Pending
- 2000-03-31 AU AU40560/00A patent/AU4056000A/en not_active Abandoned
- 2000-03-31 CA CA002366774A patent/CA2366774A1/en not_active Abandoned
- 2000-03-31 WO PCT/US2000/008581 patent/WO2000059547A2/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA2366774A1 (en) | 2000-10-12 |
US6540980B1 (en) | 2003-04-01 |
EP1169064B1 (de) | 2004-03-03 |
AU4056000A (en) | 2000-10-23 |
ATE260678T1 (de) | 2004-03-15 |
WO2000059547A2 (en) | 2000-10-12 |
EP1169064A2 (de) | 2002-01-09 |
WO2000059547A3 (en) | 2001-07-26 |
JP2002541124A (ja) | 2002-12-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |