DE50006598D1 - METHOD FOR PRODUCING CYCLO- (Asp-DPhe-NMeVal-Arg-Gly) - Google Patents

METHOD FOR PRODUCING CYCLO- (Asp-DPhe-NMeVal-Arg-Gly)

Info

Publication number: DE50006598D1
Authority: DE; Germany
Prior art keywords: nmeval; dphe; gly; asp; arg
Prior art date: 1999-03-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE50006598T

Other languages

German (de)

Inventor

Alfred Jonczyk

Markus Arnold

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Patent GmbH

Original Assignee

Merck Patent GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-11

Filing date

2000-03-01

Publication date

2004-07-01

2000-03-01 Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH

2000-03-01 Priority to DE50006598T priority Critical patent/DE50006598D1/en

2004-07-01 Application granted granted Critical

2004-07-01 Publication of DE50006598D1 publication Critical patent/DE50006598D1/en

2020-03-02 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C07K5/06095—Arg-amino acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DE50006598T 1999-03-11 2000-03-01 METHOD FOR PRODUCING CYCLO- (Asp-DPhe-NMeVal-Arg-Gly) Expired - Lifetime DE50006598D1 (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DE50006598T DE50006598D1 (en)	1999-03-11	2000-03-01	METHOD FOR PRODUCING CYCLO- (Asp-DPhe-NMeVal-Arg-Gly)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19910727		1999-03-11
DE50006598T DE50006598D1 (en)	1999-03-11	2000-03-01	METHOD FOR PRODUCING CYCLO- (Asp-DPhe-NMeVal-Arg-Gly)
PCT/EP2000/001751 WO2000053627A1 (en)	1999-03-11	2000-03-01	METHOD FOR PRODUCING CYCLO-(Asp-DPhe-NMeVal-Arg-Gly)

Publications (1)

Publication Number	Publication Date
DE50006598D1 true DE50006598D1 (en)	2004-07-01

Family

ID=7900511

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE50006598T Expired - Lifetime DE50006598D1 (en)	1999-03-11	2000-03-01	METHOD FOR PRODUCING CYCLO- (Asp-DPhe-NMeVal-Arg-Gly)

Country Status (28)

Country	Link
US (1)	US6822074B1 (en)
EP (1)	EP1159296B1 (en)
JP (1)	JP4762418B2 (en)
KR (1)	KR100645002B1 (en)
CN (1)	CN1200947C (en)
AR (1)	AR022905A1 (en)
AT (1)	ATE267839T1 (en)
AU (1)	AU762540B2 (en)
BR (1)	BR0008863A (en)
CA (1)	CA2366694C (en)
CZ (1)	CZ299879B6 (en)
DE (1)	DE50006598D1 (en)
DK (1)	DK1159296T3 (en)
ES (1)	ES2221616T3 (en)
HK (1)	HK1044780B (en)
HU (1)	HUP0200369A3 (en)
ID (1)	ID30126A (en)
MY (1)	MY120083A (en)
NO (1)	NO330030B1 (en)
PL (1)	PL202996B1 (en)
PT (1)	PT1159296E (en)
RU (1)	RU2243974C2 (en)
SE (1)	SE1159296T5 (en)
SK (1)	SK285387B6 (en)
TW (1)	TWI269798B (en)
UA (1)	UA71608C2 (en)
WO (1)	WO2000053627A1 (en)
ZA (1)	ZA200108335B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0814519D0 (en)	2008-08-08	2008-09-17	Imp Innovations Ltd	Process
WO2010130030A1 (en) *	2009-05-15	2010-11-18	National Research Counsil Of Canada	Dna sequences encoding caryophyllaceae and caryophyllaceae-like cyclopeptide precursors and methods of use
WO2010133367A2 (en) *	2009-05-20	2010-11-25	Merck Patent Gmbh	Novel solid materials of {[2s, 5r,8s,11s)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid} and methods for obtaining them
PH12012500754A1 (en)	2009-12-10	2018-03-21	Merck Patent Gmbh	Pharmaceutical composition comprising oligopeptides
US10478501B2 (en)	2011-06-09	2019-11-19	Merck Patent Gmbh	Method of treating disorders using a pharmaceutical composition of oligopeptides
US11753440B2 (en) *	2018-06-05	2023-09-12	Dsm Ip Assets B.V.	Methods for the synthesis of arginine-containing peptides

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1038741B (en) *	1956-09-14	1958-09-11	Eberhard Brecklinghaus	Made of rubber or another elastic material existing edge protectors for stairs made of concrete or the like.
US3630660A (en) *	1968-10-31	1971-12-28	Burlington Industries Inc	Process for removal of moisture and/or solvents from textile materials
UA43823C2 (en) *	1992-07-06	2002-01-15	Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг	PHARMACEUTICAL COMPOSITION FOR INTEGRIN INHIBITION <font face = "Symbol"> a </font> <sub> V </sub> <font face = "Symbol"> b </font> <sub> 3 </sub> cell adhesion mammal WAY treatment and prevention of diseases associated with cell adhesion DISORDERS, METHOD FOR BINDING LOCK integrin fibrinogen, a composition for wound healing
JPH06263798A (en) *	1993-01-13	1994-09-20	Takeda Chem Ind Ltd	Cyclic pentapeptide containing beta turn and gamma turn, its production and use thereof
DE69418353T2 (en)	1993-01-13	1999-10-28	Takeda Chemical Industries, Ltd.	Cyclic pentapeptides with beta-turn and gamma-turn
DE4310643A1 (en)	1993-04-01	1994-10-06	Merck Patent Gmbh	Cyclic adhesion inhibitors
WO1995033769A1 (en) *	1994-06-02	1995-12-14	Boehringer Mannheim Gmbh	Process and intermediate products for preparing cardiodilatin fragments, and highly purified cardiodilatin fragments
DE19534177A1 (en)	1995-09-15	1997-03-20	Merck Patent Gmbh	Cyclic adhesion inhibitors
DE19538741A1 (en)	1995-10-18	1997-04-24	Merck Patent Gmbh	Cyclopeptide derivatives
DE19613933A1 (en)	1996-04-06	1997-10-09	Merck Patent Gmbh	Cyclic adhesion inhibitors
HUP9902099A3 (en) *	1996-05-31	2001-10-29	Scripps Research Inst	Methods and compositions useful for inhibition of angiogenesis
DE19728524A1 (en)	1997-07-04	1999-01-07	Merck Patent Gmbh	Cyclic azapeptides

2000
- 2000-01-03 UA UA2001106897A patent/UA71608C2/en unknown
- 2000-03-01 DE DE50006598T patent/DE50006598D1/en not_active Expired - Lifetime
- 2000-03-01 US US09/936,230 patent/US6822074B1/en not_active Expired - Fee Related
- 2000-03-01 RU RU2001126541/04A patent/RU2243974C2/en not_active IP Right Cessation
- 2000-03-01 ID IDW00200102095A patent/ID30126A/en unknown
- 2000-03-01 PT PT00920461T patent/PT1159296E/en unknown
- 2000-03-01 AU AU41034/00A patent/AU762540B2/en not_active Ceased
- 2000-03-01 EP EP00920461A patent/EP1159296B1/en not_active Expired - Lifetime
- 2000-03-01 MY MYPI20000799A patent/MY120083A/en unknown
- 2000-03-01 BR BR0008863-3A patent/BR0008863A/en active Search and Examination
- 2000-03-01 CN CNB008048746A patent/CN1200947C/en not_active Expired - Fee Related
- 2000-03-01 WO PCT/EP2000/001751 patent/WO2000053627A1/en active IP Right Grant
- 2000-03-01 CZ CZ20013214A patent/CZ299879B6/en not_active IP Right Cessation
- 2000-03-01 SK SK1255-2001A patent/SK285387B6/en not_active IP Right Cessation
- 2000-03-01 JP JP2000604062A patent/JP4762418B2/en not_active Expired - Fee Related
- 2000-03-01 HU HU0200369A patent/HUP0200369A3/en unknown
- 2000-03-01 SE SE00820481T patent/SE1159296T5/xx unknown
- 2000-03-01 ES ES00920461T patent/ES2221616T3/en not_active Expired - Lifetime
- 2000-03-01 DK DK00920461T patent/DK1159296T3/en active
- 2000-03-01 AT AT00920461T patent/ATE267839T1/en active
- 2000-03-01 CA CA2366694A patent/CA2366694C/en not_active Expired - Fee Related
- 2000-03-01 PL PL349646A patent/PL202996B1/en not_active IP Right Cessation
- 2000-03-01 KR KR1020017011291A patent/KR100645002B1/en not_active Expired - Fee Related
- 2000-03-07 TW TW089104103A patent/TWI269798B/en not_active IP Right Cessation
- 2000-03-10 AR ARP000101079A patent/AR022905A1/en active IP Right Grant
2001
- 2001-09-10 NO NO20014383A patent/NO330030B1/en not_active IP Right Cessation
- 2001-10-10 ZA ZA200108335A patent/ZA200108335B/en unknown
2002
- 2002-08-29 HK HK02106365.2A patent/HK1044780B/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2366694C (en)	2010-07-20
US6822074B1 (en)	2004-11-23
SE1159296T3 (en)	2004-08-24
UA71608C2 (en)	2004-12-15
PT1159296E (en)	2004-10-29
EP1159296B1 (en)	2004-05-26
MY120083A (en)	2005-08-30
AR022905A1 (en)	2002-09-04
HUP0200369A3 (en)	2002-09-30
ID30126A (en)	2001-11-08
NO330030B1 (en)	2011-02-07
HUP0200369A2 (en)	2002-06-29
SE1159296T5 (en)	2004-09-07
KR20010102503A (en)	2001-11-15
JP4762418B2 (en)	2011-08-31
NO20014383L (en)	2001-11-02
AU762540B2 (en)	2003-06-26
ZA200108335B (en)	2003-01-10
DK1159296T3 (en)	2004-09-27
CZ20013214A3 (en)	2001-12-12
TWI269798B (en)	2007-01-01
HK1044780B (en)	2005-08-26
SK285387B6 (en)	2006-12-07
ATE267839T1 (en)	2004-06-15
CN1200947C (en)	2005-05-11
CN1343220A (en)	2002-04-03
PL202996B1 (en)	2009-08-31
EP1159296A1 (en)	2001-12-05
JP2002539137A (en)	2002-11-19
HK1044780A1 (en)	2002-11-01
NO20014383D0 (en)	2001-09-10
WO2000053627A1 (en)	2000-09-14
CZ299879B6 (en)	2008-12-17
AU4103400A (en)	2000-09-28
SK12552001A3 (en)	2002-05-09
BR0008863A (en)	2002-01-02
ES2221616T3 (en)	2005-01-01
CA2366694A1 (en)	2000-09-14
RU2243974C2 (en)	2005-01-10
KR100645002B1 (en)	2006-11-10

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Legal Events

Date	Code	Title	Description
2005-06-23	8364	No opposition during term of opposition