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DE3887071D1 - Immunoreactive carrier material. - Google Patents

Immunoreactive carrier material.

Info

Publication number
DE3887071D1
DE3887071D1 DE88116972T DE3887071T DE3887071D1 DE 3887071 D1 DE3887071 D1 DE 3887071D1 DE 88116972 T DE88116972 T DE 88116972T DE 3887071 T DE3887071 T DE 3887071T DE 3887071 D1 DE3887071 D1 DE 3887071D1
Authority
DE
Germany
Prior art keywords
porous support
carrier material
immunoreactive
immune complexes
produced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88116972T
Other languages
German (de)
Inventor
Dieter Dr Mangold
Siegfried Dr Noetzel
Rolf Lerch
Helmut Dr Rer Nat Jering
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE88116972T priority Critical patent/DE3887071D1/en
Application granted granted Critical
Publication of DE3887071D1 publication Critical patent/DE3887071D1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Laminated Bodies (AREA)
  • Materials For Medical Uses (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The material consists of a porous support material and immune complexes precipitated thereon and is characterised in that the porous support material is treated with one or more wet strength agents and is produced as described. This markedly improves the matrix binding of immune complexes to the support materials produced in this way. <??>The immunoreactive porous support materials can be used in immunoassays. <IMAGE>
DE88116972T 1987-10-22 1988-10-13 Immunoreactive carrier material. Expired - Fee Related DE3887071D1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE88116972T DE3887071D1 (en) 1987-10-22 1988-10-13 Immunoreactive carrier material.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873735684 DE3735684A1 (en) 1987-10-22 1987-10-22 IMMUNREACTIVE CARRIER MATERIAL AND METHOD FOR THE PRODUCTION THEREOF
DE88116972T DE3887071D1 (en) 1987-10-22 1988-10-13 Immunoreactive carrier material.

Publications (1)

Publication Number Publication Date
DE3887071D1 true DE3887071D1 (en) 1994-02-24

Family

ID=6338812

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19873735684 Withdrawn DE3735684A1 (en) 1987-10-22 1987-10-22 IMMUNREACTIVE CARRIER MATERIAL AND METHOD FOR THE PRODUCTION THEREOF
DE88116972T Expired - Fee Related DE3887071D1 (en) 1987-10-22 1988-10-13 Immunoreactive carrier material.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19873735684 Withdrawn DE3735684A1 (en) 1987-10-22 1987-10-22 IMMUNREACTIVE CARRIER MATERIAL AND METHOD FOR THE PRODUCTION THEREOF

Country Status (6)

Country Link
US (1) US5177022A (en)
EP (1) EP0312907B1 (en)
JP (1) JPH01141354A (en)
AT (1) ATE100205T1 (en)
DE (2) DE3735684A1 (en)
ES (1) ES2049235T3 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69108628T2 (en) * 1990-07-26 1995-08-31 Taiho Kogyo Co Ltd Metal gasket.
DE69209009T2 (en) * 1991-11-25 1996-08-29 Taiho Kogyo Co Ltd Metal gasket
DE4212280A1 (en) * 1992-04-11 1993-10-14 Boehringer Mannheim Gmbh Asymmetrically porous membranes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA983358A (en) * 1971-09-08 1976-02-10 Kenneth D. Bagshawe Performance of chemical or biological reactions
JPS5622956A (en) * 1979-07-09 1981-03-04 Corning Glass Works Manufacture of reagenttbinding agent film
US4786606A (en) * 1981-01-23 1988-11-22 Baxter Travenol Laboratories, Inc. Solid phase system for ligand assay
DE3269567D1 (en) * 1981-04-29 1986-04-10 Ciba Geigy Ag New devices and kits for immunological analysis
US4504582A (en) * 1982-07-20 1985-03-12 Genex Corporation Vermiculite as a carrier support for immobilized biological materials
DE3425008A1 (en) * 1984-07-06 1986-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim METHOD AND DEVICE FOR CARRYING OUT ANALYTICAL PROVISIONS
DE3446636A1 (en) * 1984-12-20 1986-06-26 Boehringer Mannheim Gmbh, 6800 Mannheim METHOD FOR PRODUCING AN IMMUNREACTIVE POROUS CARRIER MATERIAL
JPS6255084A (en) * 1985-04-04 1987-03-10 ジエネツクス・コ−ポレイシヨン Method for immobilizing living body and insoluble living body composite obtained therefrom
DE3543749A1 (en) * 1985-12-11 1987-06-19 Boehringer Mannheim Gmbh METHOD FOR PRODUCING A REAGENT PAPER FOR IMMUNOLOGICAL ANALYSIS
DE3620653A1 (en) * 1986-06-20 1987-12-23 Boehringer Mannheim Gmbh METHOD FOR PRODUCING AN IMMUNREACTIVE SUPPORT MATERIAL FOR HETEROGENEOUS IMMUNOLOGICAL ANALYSIS

Also Published As

Publication number Publication date
ES2049235T3 (en) 1994-04-16
JPH01141354A (en) 1989-06-02
EP0312907A3 (en) 1990-10-10
ATE100205T1 (en) 1994-01-15
EP0312907B1 (en) 1994-01-12
US5177022A (en) 1993-01-05
DE3735684A1 (en) 1989-05-03
EP0312907A2 (en) 1989-04-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS GMBH, 68305 MANNHEIM, DE

8339 Ceased/non-payment of the annual fee