[go: up one dir, main page]

DE3869286D1 - Imidazo(1,2-b)pyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. - Google Patents

Imidazo(1,2-b)pyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.

Info

Publication number
DE3869286D1
DE3869286D1 DE8888402199T DE3869286T DE3869286D1 DE 3869286 D1 DE3869286 D1 DE 3869286D1 DE 8888402199 T DE8888402199 T DE 8888402199T DE 3869286 T DE3869286 T DE 3869286T DE 3869286 D1 DE3869286 D1 DE 3869286D1
Authority
DE
Germany
Prior art keywords
alkyl group
imidazo
pyridazine
denotes hydrogen
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888402199T
Other languages
English (en)
Inventor
Jean Jacques Bourguignon
Camille George Wermuth
Paul Worms
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Application granted granted Critical
Publication of DE3869286D1 publication Critical patent/DE3869286D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8888402199T 1987-09-01 1988-09-01 Imidazo(1,2-b)pyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. Expired - Fee Related DE3869286D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8712167A FR2619818B1 (fr) 1987-09-01 1987-09-01 Imidazo (1,2-b) pyridazines, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
DE3869286D1 true DE3869286D1 (de) 1992-04-23

Family

ID=9354553

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888402199T Expired - Fee Related DE3869286D1 (de) 1987-09-01 1988-09-01 Imidazo(1,2-b)pyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.

Country Status (8)

Country Link
US (1) US4910199A (de)
EP (1) EP0306408B1 (de)
JP (1) JPS6471877A (de)
AT (1) ATE73803T1 (de)
CA (1) CA1310318C (de)
DE (1) DE3869286D1 (de)
FR (1) FR2619818B1 (de)
PT (1) PT88373B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601011B1 (fr) * 1986-07-03 1988-10-28 Sanofi Sa Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant
FR2625201B1 (fr) * 1987-12-24 1990-06-15 Sanofi Sa Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant
AU4859596A (en) * 1995-02-15 1996-09-04 Pharmacia & Upjohn Company Imidazo{1,2-a}pyridines for the treatment of cns and cardiac diseases
US6013654A (en) * 1997-08-14 2000-01-11 Pharmacia & Upjohn Company Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases
TWI312347B (en) * 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
US7723336B2 (en) 2005-09-22 2010-05-25 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
US20070078136A1 (en) * 2005-09-22 2007-04-05 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
EP2240488B1 (de) 2008-02-06 2016-11-02 Bristol-Myers Squibb Company Als kinasehemmer geeignete substituierte imidazopyridazine
PE20091468A1 (es) * 2008-02-28 2009-10-22 Novartis Ag DERIVADOS DE 3-METIL-IMIDAZO-[1,2-b]-PIRIDAZINA
KR101601994B1 (ko) * 2008-04-15 2016-03-17 에자이 알앤드디 매니지먼트 가부시키가이샤 3-페닐피라졸로[5,1-ｂ]티아졸 화합물
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
WO2011043387A1 (ja) * 2009-10-08 2011-04-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピラゾロオキサゾール化合物
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
UA117092C2 (uk) 2011-09-06 2018-06-25 Байєр Інтеллектуал Проперті Гмбх Амінозаміщені імідазопіридазини
JP2015537017A (ja) 2012-11-19 2015-12-24 バイエル ファーマ アクチエンゲゼルシャフト アミノイミダゾピリダジン類

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489755A (en) * 1966-08-03 1970-01-13 Pfizer & Co C Imidazo (1,2-b) pyridazines
US3828041A (en) * 1971-02-24 1974-08-06 American Cyanamid Co 6-substituted 3-nitroimidazo(1,2-b)pyridazines and method of preparing same
FR2473522A1 (fr) * 1980-01-16 1981-07-17 Synthelabo Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent
US4464372A (en) * 1982-08-16 1984-08-07 Schering Corporation Imidazo[1,2-b]pyridazines
US4569934A (en) * 1984-10-09 1986-02-11 American Cyanamid Company Imidazo[1,2-b]pyridazines

Also Published As

Publication number Publication date
FR2619818A1 (fr) 1989-03-03
EP0306408B1 (de) 1992-03-18
EP0306408A1 (de) 1989-03-08
PT88373B (pt) 1992-10-30
US4910199A (en) 1990-03-20
CA1310318C (en) 1992-11-17
FR2619818B1 (fr) 1990-01-12
JPS6471877A (en) 1989-03-16
ATE73803T1 (de) 1992-04-15
PT88373A (pt) 1989-07-31

Similar Documents

Publication Publication Date Title
DE3869286D1 (de) Imidazo(1,2-b)pyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
ATE76074T1 (de) 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel.
ATE51231T1 (de) Pyrimidopyrimidinderivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zubereitungen und ihre verwendung als antiallergische mittel.
DE3380958D1 (de) Beta-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
ATE57701T1 (de) Pyridoindolderivate, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.
DK231686A (da) Oxadiazolylimidazobenzodiazepinforbindelse, farmaceutisk praeparat indeholdende samme, fremgangsmaade til fremstilling af forbindelsen og fremgangsmaade til behandling af en centralnervesystemsygdom
ATE18050T1 (de) Triazolochinazoline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
ATE11915T1 (de) Benzothiazolderivate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung.
ATE74605T1 (de) Tetracyclische chinazolinderivate, herstellung und verwendung.
DE3870167D1 (de) N-(vinblastinoyl-23)-derivate von 1-aminomethylposphonsaeure, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.
ATE70827T1 (de) Benzhydryloxyaethyl-piperidine-derivate, verfahren zur herstellung und pharmazeutische zusammenstellungen, die diese enthalten.
ES2138226T3 (es) Derivados del acido imidazo(1,2-a)indeno(1,2-e)pirazina-2-carboxilico, su preparacion y los medicamentos que les contienen.
ATE62244T1 (de) Pyrrolo(1,2-a>(4,1>benzoxazepine, verfahren zur ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen, sowie therapeutische verwendung.
ATE219082T1 (de) Verfahren zur herstellung von radioaktiv markierten benzodiazepinrezeptor-mitteln und diese enthaltende zubereitung
DK197689A (da) Pyridazinderivater
PT82175A (de) Neue 3-pyridylmethylnaphthylderivate verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE66226T1 (de) Tetrahydro-beta-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE86993T1 (de) Heterotetracyclische laktamderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
ZA891108B (en) Basic-substituted 5-halo-thienoisothiazol-3(2h)-one 1,1-dioxides,a process for the preparation thereof,and pharmaceutical preparations containing these compounds
NO164027C (no) Analogifremgangsmaate til fremstilling av terapeutiske tricykliske pyridazopyridonderivater.
ATE101610T1 (de) Indol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
ATE59035T1 (de) Basisch substituierte benzofurancarbonsaeureamide, verfahren zu ihrer herstellung und sie enthaltende therapeutische mittel.
ATE2429T1 (de) 6-imidazol-1-yl-3-hydrazino-pyridazine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
DK231586A (da) Oxadiazolylimidazobenzodiazepinforbindelse, farmaceutisk praeparat indeholdende samme, fremgangsmaade til fremstilling af forbindelsen og fremgangsmaade til behandling af en centralnervesystemsygdom
ATE111467T1 (de) 4h-pyrrolo(1,2-a>thieno(3,2- f>(1,4>diazepinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.

Legal Events

Date Code Title Description
8380 Miscellaneous part iii

Free format text: DER PATENTINHABER LAUTET RICHTIG: ELF SANOFI, PARIS, FR

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee