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DE3869135D1 - Kontrollierte freisetzung von antibiotika-salzen aus einem implantat. - Google Patents

Kontrollierte freisetzung von antibiotika-salzen aus einem implantat.

Info

Publication number
DE3869135D1
DE3869135D1 DE8888906477T DE3869135T DE3869135D1 DE 3869135 D1 DE3869135 D1 DE 3869135D1 DE 8888906477 T DE8888906477 T DE 8888906477T DE 3869135 T DE3869135 T DE 3869135T DE 3869135 D1 DE3869135 D1 DE 3869135D1
Authority
DE
Germany
Prior art keywords
antibiotic
controlled release
implant
pct
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888906477T
Other languages
English (en)
Inventor
L Putnam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DE3869135D1 publication Critical patent/DE3869135D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
DE8888906477T 1987-07-29 1988-07-01 Kontrollierte freisetzung von antibiotika-salzen aus einem implantat. Expired - Fee Related DE3869135D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7918887A 1987-07-29 1987-07-29
PCT/US1988/002180 WO1989000852A1 (en) 1987-07-29 1988-07-01 Controlled release of antibiotic salts from an implant

Publications (1)

Publication Number Publication Date
DE3869135D1 true DE3869135D1 (de) 1992-04-16

Family

ID=22148979

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888906477T Expired - Fee Related DE3869135D1 (de) 1987-07-29 1988-07-01 Kontrollierte freisetzung von antibiotika-salzen aus einem implantat.

Country Status (8)

Country Link
US (1) US5079007A (de)
EP (1) EP0386000B1 (de)
AT (1) ATE73333T1 (de)
AU (1) AU611461B2 (de)
CA (1) CA1325975C (de)
DE (1) DE3869135D1 (de)
DK (1) DK169536B1 (de)
WO (1) WO1989000852A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA941586B (en) * 1993-03-12 1995-09-07 Upjohn Co Crystalline ceftiofur free acid
US6074657A (en) * 1997-03-20 2000-06-13 Pharmacia & Upjohn Company Administration of an injectable antibiotic in the ear of an animal
US6358526B1 (en) * 2000-08-16 2002-03-19 Rexall Sundown Method of making tablets and tablet compositions produced therefrom
KR100423895B1 (ko) * 2001-02-19 2004-03-24 주식회사 엘지생명과학 셉티오퍼 하이드로클로라이드의 현탁제 조성물
DE60309447T3 (de) * 2002-03-21 2020-04-23 Zoetis Services LLC (n.d.Ges.d.Staates Delaware) Verfahren zur verabreichung von injizierbarem antibiotikum in dem ohr eines tieres
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
US8470809B2 (en) * 2005-10-12 2013-06-25 Orchid Chemicals & Pharmaceuticals Limited Crystalline sodium salt of cephalosporin antibiotic
WO2007063552A1 (en) * 2005-12-02 2007-06-07 Lupin Limited Stable taste masked formulations of cephalosporins
EP2062909A1 (de) * 2007-11-21 2009-05-27 SOLVAY (Société Anonyme) Herstellung von Peptiden und Reinigungsverfahren
EP2324034A4 (de) * 2008-08-22 2012-05-16 Orchid Chemicals & Pharm Ltd Kristallines natriumsalz eines cephalosporin-antibiotikums
RU2641962C2 (ru) * 2013-07-03 2018-01-23 С.П. Ветеринариа, С.А. Инъецируемая ветеринарная композиция

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2479229B1 (fr) * 1980-03-26 1986-01-17 Clin Midy Nouveaux derives des cephalosporines, leur procede de preparation et les medicaments utilisables comme antibiotiques qui contiennent lesdits derives
EP0050650A1 (de) * 1980-04-21 1982-05-05 University Of Southern California Arzneiformulierung mit verlängerter aktion
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
US4902683A (en) * 1984-10-25 1990-02-20 The Upjohn Company Crystalline cephalosporin hydrohalide salts
US4877782A (en) * 1988-02-16 1989-10-31 The Upjohn Company Zinc ceftiofur complexes

Also Published As

Publication number Publication date
AU1969088A (en) 1989-03-01
DK169536B1 (da) 1994-11-28
DK23490A (da) 1990-01-29
US5079007A (en) 1992-01-07
ATE73333T1 (de) 1992-03-15
AU611461B2 (en) 1991-06-13
DK23490D0 (da) 1990-01-29
WO1989000852A1 (en) 1989-02-09
CA1325975C (en) 1994-01-11
EP0386000B1 (de) 1992-03-11
EP0386000A1 (de) 1990-09-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee