DE3831254A1 - Process for the production of a composition for reviving and for stimulating and strengthening hair growth - Google Patents
Process for the production of a composition for reviving and for stimulating and strengthening hair growthInfo
- Publication number
- DE3831254A1 DE3831254A1 DE3831254A DE3831254A DE3831254A1 DE 3831254 A1 DE3831254 A1 DE 3831254A1 DE 3831254 A DE3831254 A DE 3831254A DE 3831254 A DE3831254 A DE 3831254A DE 3831254 A1 DE3831254 A1 DE 3831254A1
- Authority
- DE
- Germany
- Prior art keywords
- concentrate
- vitamin
- hair growth
- stimulating
- seeds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title claims abstract description 11
- 230000003779 hair growth Effects 0.000 title claims abstract description 8
- 230000004936 stimulating effect Effects 0.000 title claims abstract description 4
- 238000005728 strengthening Methods 0.000 title claims abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract description 4
- 239000000203 mixture Substances 0.000 title abstract 2
- WWNNZCOKKKDOPX-UHFFFAOYSA-N N-methylnicotinate Chemical compound C[N+]1=CC=CC(C([O-])=O)=C1 WWNNZCOKKKDOPX-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000012141 concentrate Substances 0.000 claims abstract description 10
- 239000002253 acid Substances 0.000 claims abstract description 9
- 244000250129 Trigonella foenum graecum Species 0.000 claims abstract description 7
- 229930013930 alkaloid Natural products 0.000 claims abstract description 6
- 150000003797 alkaloid derivatives Chemical class 0.000 claims abstract description 6
- 229940088594 vitamin Drugs 0.000 claims abstract description 6
- 235000013343 vitamin Nutrition 0.000 claims abstract description 6
- 239000011782 vitamin Substances 0.000 claims abstract description 6
- 229930003231 vitamin Natural products 0.000 claims abstract description 6
- 150000003722 vitamin derivatives Chemical class 0.000 claims abstract description 6
- 239000003755 preservative agent Substances 0.000 claims abstract description 5
- 230000002335 preservative effect Effects 0.000 claims abstract description 5
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 5
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 4
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 4
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 2
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 2
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims description 2
- 229960002079 calcium pantothenate Drugs 0.000 claims description 2
- 239000002775 capsule Substances 0.000 claims description 2
- 239000003995 emulsifying agent Substances 0.000 claims description 2
- 229960000304 folic acid Drugs 0.000 claims description 2
- 235000019152 folic acid Nutrition 0.000 claims description 2
- 239000011724 folic acid Substances 0.000 claims description 2
- 235000020344 instant tea Nutrition 0.000 claims description 2
- 229960003966 nicotinamide Drugs 0.000 claims description 2
- 235000005152 nicotinamide Nutrition 0.000 claims description 2
- 239000011570 nicotinamide Substances 0.000 claims description 2
- 229960002477 riboflavin Drugs 0.000 claims description 2
- 235000019192 riboflavin Nutrition 0.000 claims description 2
- 239000002151 riboflavin Substances 0.000 claims description 2
- 241001312519 Trigonella Species 0.000 claims 1
- 230000008020 evaporation Effects 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 235000001484 Trigonella foenum graecum Nutrition 0.000 abstract description 2
- 235000001019 trigonella foenum-graecum Nutrition 0.000 abstract description 2
- 210000003780 hair follicle Anatomy 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 210000004209 hair Anatomy 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 206010020864 Hypertrichosis Diseases 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Birds (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
Description
Die Erfindung betrifft ein Verfahren zum Herstellen eines Mittels zur Wiederbelebung und zum Anregen und Verstärken des Haarwuchses bei Lebewesen.The invention relates to a method for manufacturing a means of reviving and stimulating and Enhance hair growth in living beings.
In der Vergangenheit sind eine Vielzahl von Haarwuchs mitteln entwickelt, getestet und auf den Markt gebracht worden. Leider hat keines dieser Mittel die gewünschte Wirkung gezeigt oder es hatte erhebliche Nebenwirkungen gehabt. In the past there have been a lot of hair growth developed, tested and launched on the market been. Unfortunately, none of these remedies have the desired one Has shown effect or had significant side effects had.
Das Ausdünnen oder Zurückfliehen des Haarwuchses ist meist auf eine zu starke Straffung der Kopfhaut zurück zuführen, wodurch die Zirkulation des Blutes zu den Haarfolikeln unterbrochen oder unterbunden wird. Die zurückgehende Zufuhr von Nährstoffen und Sauerstoff zu den Haarfolikeln hat einen ungünstigen Einfluß auf die Produktion des Protein Keratin, welches wesentlich für das Haarwachstum verantwortlich ist.The thinning or fleeing of hair growth is mostly due to an excessive tightening of the scalp feed, causing the circulation of blood to the Hair follicles is interrupted or prevented. The declining supply of nutrients and oxygen too the hair follicles has an unfavorable influence on the Production of the protein keratin, which is essential for hair growth is responsible.
In der Deutschen Patentanmeldung P 36 03 601 wird von den Erfindern der vorliegenden Erfindung ein Mittel zur Wiederbelebung und zum Anregen und Verstärken des Haar wuchses beschrieben, wobei das Mittel das Alkaloid Trigonellin bzw. Trigonellinsäure enthält. Ferner wird dort beansprucht, daß dieses Mittel aus einem Extrakt der Pflanze Bockshornklee besteht.In German patent application P 36 03 601 from to the inventors of the present invention Revitalize and stimulate and strengthen the hair described growth, the agent being the alkaloid Trigonellin or trigonellic acid contains. Furthermore, there claims that this agent is from an extract of the fenugreek plant.
Aufgabe der vorliegenden Erfindung ist es nun, Ver fahren aufzuzeigen, die einfache Möglichkeiten des Her stellens dieses Mittels betreffen.The object of the present invention is now to Ver drive to demonstrate the simple possibilities of the fro of this remedy.
Zur Lösung dieser Aufgabe führt ein Verfahren, bei dem aus dem Samen der Pflanze Bockshornklee (Trigonella foenum graecum) das Alkaloid Trigonellin bzw. Trigo nellinsäure extrahiert, mit einem Vitamin sowie Konser vierungsmittel versetzt und sodann zu einem Konzentrat eingedickt wird.A method in which from the seeds of the fenugreek plant (Trigonella foenum graecum) the alkaloid trigonelline or trigo Nellic acid extracted with a vitamin as well as preservative Adding agent and then to a concentrate is thickened.
Wie bereits in der DE-OS 36 03 601 beschrieben, bewirkt die Substanz Trigonellin bzw. Trigonellinsäure eine Er weiterung der Blutgefäße, wodurch eine bessere Lieferung von Nährstoffen zu den Haarfolikeln möglich wird. As already described in DE-OS 36 03 601, causes the substance trigonellin or trigonellic acid an Er dilation of the blood vessels, creating a better Delivery of nutrients to the hair follicles possible becomes.
Die Haarfolikel werden wiederbelebt, wobei die Wieder belebung von einer Hypertrichose, d. h. Verlängerung, Verdickerung und erhöhter Pigmentierung des Haares, begleitet ist.The hair follicles are revived, with the re resuscitation from hypertrichosis, d. H. Renewal, Thickening and increased pigmentation of the hair, is accompanied.
Eine Möglichkeit des Erzielens des o. g. Stoffes aus den Samen der Pflanze Bockshornklee besteht darin, daß der Samen kalt gepreßt und der gewonnene Saft und/oder die Maische mit dem entsprechenden Vitamin bzw. dem Konservierungsmittel versetzt wird. Sowohl im Saft wie auch in der Maische ist genügend Substanz vorhanden, um die gewünschte Wirkung bezüglich des Haarwuches zu er zielen.One way of achieving the above. Fabric The seeds of the fenugreek plant consist of: the seeds are cold pressed and the juice obtained and / or the mash with the appropriate vitamin or Preservative is added. Both in juice as there is also sufficient substance in the mash to the desired effect in terms of hair growth aim.
In einem anderen, bevorzugten Verfahren wird dagegen der Samen mit einem Alkohol versetzt und adurch das Alkaloid Trigonellin bzw. Trigonellinsäure extrahiert. Alkohol hat den Vorteil, daß er leichter verdunstet und somit das Trigonellin bzw. die Trigonellinsäure leicht wieder vom Alkohol gelöst werden kann. Als wirkungsvoll hat sich hier Methanol erwiesen.In another, preferred method is against the seed is mixed with alcohol and by that Alkaloid trigonelline or trigonellic acid extracted. Alcohol has the advantage that it evaporates more easily and thus the trigonellin or trigonellic acid easily can be detached from alcohol. As effective methanol has proven here.
In jedem Fall sollte das Konzentrat, sei es der Saft, die Maische oder das durch Alkoholextraktion gewonnene Trigonellin bzw. Trigonellinsäure mit einem Emulgator, insbesondere Riboflavin und/oder Nikotinamid und/oder Calziumpantothenat und/oder Folsäure versetzt werden. In diesem Fall ist es möglich, das Konzentrat mit einer zersetzbaren Einnahmekapsel zu umhüllen und so in einen gebrauchsfähigen Zustand zu versetzen.In any case, the concentrate, be it the juice, the mash or that obtained by alcohol extraction Trigonellin or trigonellic acid with an emulsifier, in particular riboflavin and / or nicotinamide and / or Calcium pantothenate and / or folic acid are added. In this case it is possible to use a concentrate to encapsulate a decomposable taking capsule and thus into one usable condition.
Eine andere Möglichkeit besteht darin, daß das Konzen trat gesprüht und die Tropfen getrocknet werden. Another possibility is that the Konzen kicked sprayed and the drops are dried.
Diese getrockneten Tropfen werden dann als Körner eingesammelt, so daß ein Instant-Tee hergestellt wird, wobei sich diese Körner bei Zugabe von einer ent sprechenden Flüssigkeit auflösen und so in einer ein nahmefertigen Darreichungsform anbieten.These dried drops are then called grains collected so that an instant tea is made where these grains with the addition of an ent dissolving speaking liquid and so in one offer ready-to-use dosage form.
Einfach ist auch die Möglichkeit, das Konzentrat in Tropfflaschen abzufüllen, so daß der Verwender eine be stimmte Anzahl von Tropfen in eine entsprechende Flüssigkeit eingeben und diese Flüssigkeit einnehmen kann.It is also easy to put the concentrate in Bottling dropper bottles so that the user can be a agreed number of drops in a corresponding Enter liquid and take this liquid can.
Claims (6)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3831254A DE3831254A1 (en) | 1988-09-14 | 1988-09-14 | Process for the production of a composition for reviving and for stimulating and strengthening hair growth |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3831254A DE3831254A1 (en) | 1988-09-14 | 1988-09-14 | Process for the production of a composition for reviving and for stimulating and strengthening hair growth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3831254A1 true DE3831254A1 (en) | 1990-03-15 |
Family
ID=6362947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3831254A Withdrawn DE3831254A1 (en) | 1988-09-14 | 1988-09-14 | Process for the production of a composition for reviving and for stimulating and strengthening hair growth |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE3831254A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0640333A2 (en) * | 1993-08-09 | 1995-03-01 | Tsumura & Co. | Hair growth promoting aerosol formulation |
| WO1997013492A2 (en) * | 1995-10-10 | 1997-04-17 | Jutta Mai | Strengthening agent |
-
1988
- 1988-09-14 DE DE3831254A patent/DE3831254A1/en not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0640333A2 (en) * | 1993-08-09 | 1995-03-01 | Tsumura & Co. | Hair growth promoting aerosol formulation |
| EP0640333A3 (en) * | 1993-08-09 | 1997-04-02 | Tsumura & Co | Spray formulation that promotes hair growth. |
| WO1997013492A2 (en) * | 1995-10-10 | 1997-04-17 | Jutta Mai | Strengthening agent |
| WO1997013492A3 (en) * | 1995-10-10 | 2001-09-13 | Jutta Mai | Strengthening agent |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8139 | Disposal/non-payment of the annual fee |